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An innovative platform for treatment of vascular obstructions: System design and preliminary results 3
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P. Miloro ; M. Khorami Llewellyn ; S. Tognarelli ; G. Ciuti ; E. Sinibaldi ; P. Dario ; A. Menciassi
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Abstract: The quest for miniaturization of interventional devices and the integration between external surgical platforms and internal therapeutic tools are continuously fostering research in the biomedical field. Operating in the cardiovascular system poses dramatic challenges, but it also represent the elective application for highly targeted therapeutic devices. In this paper we present a robotic platform for treating vascular obstructions. It integrates a system for locomotion and navigation based on magnetic dragging and ultrasound tracking, a therapeutic module which involves mechanical attack to the obstruction by means of high intensity focused ultrasound, and a collection/retrieval module exploiting magnetic nano-particles to bind the obstruction debris and to drag them to a safe region for removal. Here we illustrate the system overview and the technical and theoretical instruments for developing the overall platform; preliminary results, together with future planned works, are reported in order to demonstrate the feasibility of the proposed approach. Published in: Biomedical Robotics and Biomechatronics (BioRob), 2012 4th IEEE RAS & EMBS International Conference on Date of Conference: 24-27 June 2012 Date Added to IEEE Xplore: 31 August 2012 ISBN Information: ISSN Information: INSPEC Accession Number: 12967923 DOI: 10.1109/BioRob.2012.6290758 Publisher: IEEE Conference Location: Rome, Italy
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I. Introduction CARDIOVASCULAR diseases are the leading cause of death worldwide; the increase in life expectancy, sedentary lifestyle and a meat-based diet has further risen the incidence of these disorders in the past few decades. The occurrence of vessels occlusions (namely atherosclerotic plaques and blood clots) which lead to pain, lasting damages to the tissues or death, are the major threats of cardiovascular disorders. Cardiovascular research resulted in the development of variety of techniques for treating occlusions; the state-of-the-art of current strategies is populated by a plethora of strategies, which runs from pharmacological approach, to percutaneous intervention (PCI) via dedicated catheters, or even to open surgery. However, all these strategies suffer from risks and limitations. Read document
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