Ayurvedic Management of Incontinence of Urine in Aged [PDF]

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Int J Ayu Pharm Chem RESEARCH ARTICLE

www.ijapc.com

e-ISSN 2350-0204 Ayurvedic Management of Incontinence of Urine in Aged Patel Manish1*, Ka. Patel Nimesh2, Kalapi B Patel3, Gupta S N4, Kulashreshtha D5, and Jain Jinesh6 1,4

Department of Kayachikitsa, J. S. Ayurveda College, Nadiad,Gujarat, India

2

Department of Svasthavritta, J S Ayurveda College, Nadiad,Gujarat, India

3

Department of Panchakarma, J. S. Ayurveda College, Nadiad,Gujarat, India

5

Government (Auto) Ayurveda College, Rewa, MP, India

6

Department of Panchakarma, Government (Auto) Ayurveda College, Rewa, MP, India

ABSTRACT Urinary incontinence is defined as the involuntary loss of urine, sufficiently severe to cause a social or hygiene problem. It becomes more prevalent in old age mainly after 60 years of age. In Ayurveda, this condition can be concluded under the heading of predominant vata disorders. In old age Vata aggravated and creates this condition. For the first time we aimed to evaluate the principle potential of the traditional Ayurvedic approach for the overall clinical outcomes in incontinence of urine in aged. The observational clinical study with 15 patients was conducted at P.D. Patel Ayurveda Hospital, Nadiad, India. Patients were treated with Bala moola kvath, Narayanaa oil orally for one month period along with narayanaa oil abhyanga, nirgundi patra baspasvedana, narayana oil matrabasti. Patients were trained for Kegel exercise and advised to do it for 15 minutes twice every day. Moreover, dietary advice was given. Total duration of the treatment was of 1 month along with 2 months of follow-up period. Assessment was done on the basis of grade score prepared for the urgency and incontinency of urine. Disturbances in daily routine activities also assessed with the help of King’s Health Questionnaire. Statistically significant improvement was noticed in incontinence of urine by 66.6% and in urine urgency by 57.14%. Affected daily activities due to incontinence were also improved. No any unwanted sign or symptom was noticed and the signs and symptoms of the disease as well as daily activities improved in the follow-up period.

KEYWORDS Urinary Incontinence, Matrabasti, Kegel Exercise, Abhyanga, Baspasvedana

Greentree Group Received 25/06/17 Accepted 01/07/17 Published 10/07/17 ________________________________________________________________________________________________________ Patel et al. 2017 Greentree Group © IJAPC Int J Ayu Pharm Chem 2017 Vol. 7 Issue 1 www.ijapc.com 311 [e ISSN 2350-0204]

Int J Ayu Pharm Chem

INTRODUCTION

estimates

Urinary incontinence is the loss of bladder

patients varying enormously (2–58%).9-12

control. This means that one can't always

The

control when urinate. Urinary incontinence

incontinence in institutionalized patients is

can range from leaking a small amount of

even higher, with many authors suggesting a

urine (such as when coughing or laughing)

prevalence of 40–60%. Despite these high

to having very strong urges to urinate that

prevalence rates, urinary incontinence is not

are difficult to control.

a static condition. Rather it is a dynamic

Aging causes a number of changes in

condition whereby significant incidence

urinary tract physiology like decreasing

rates are associated with equally significant

bladder elasticity, urethral closing pressure

remission rates, and patients move back and

and strength of the detrusor muscle, all of

forth from continence to incontinence13.

which can affect continence1. In addition,

Treatment of this condition available in

with age, the kidneys become less efficient

allopathic medicine have not satisfactory

at concentrating urine, causing an increase

role in achieving the success in addition to

in urine volume. Main causative factors for

their adverse effects. Owing to the above

incontinence of urine in old age are acute

mentioned problems of management, it is

confusional state, urinary tract infection,

imperative to explore newer efficacious

some

drugs of procedures to tackle such disease

medications,

faecal

impaction,

restricted mobility and detrusor over activity

among

lower

community

prevalence

of

dwelling

urinary

entities.

caused by damage to central inhibitory centers

or

local

detrusor

muscle

AIMS AND OBJECTIVES

abnormalities.2

The present study was aimed to establish

Millions of adults have urinary incontinence.

clinically, the effect of Ayurvedic multi-

It is most common in people over 65 years

modal

old, especially women. In aged people

medicines i.e. balamoola

urinary incontinence is mainly of urge or

narayana taila and abhyanga, baspasvedana

stress

Numerous

with narayana taila matrabasti as well as

that

specific Kegel exercise in the aged patients

or

epidemiologic

both studies

types. show

the

incidence of urinary incontinence increases

treatment

which

consist

oral

kvatha

with

of urinary incontinence.

with age3-8 with the range of prevalence ________________________________________________________________________________________________________ Patel et al. 2017 Greentree Group © IJAPC Int J Ayu Pharm Chem 2017 Vol. 7 Issue 1 www.ijapc.com 312 [e ISSN 2350-0204]

Int J Ayu Pharm Chem

Effect of this treatment on daily life style



with the help of improvement noticed in

with the pattern of micturition that defining

King’s Health Questionnaire was also an

the incontinence of the urine with the help of

objective of this study.

criteria given by the ICI (International

MATERIALS AND METHODS

consultation on incontinence’s).14

Selection of the patient



All patients meeting the criteria (see below)

also done to exclude the patient suffered

were selected from both the out-patient

from disorders like multiple sclerosis, and

department

the lumbar spine should be inspected for

(OPD)

and

the

in-patient

Each and every patient were selected

General neurological assessment was

department (IPD) of the P. D. Patel Ayurved

features of spina bifida occulta etc.

Hospital in Nadiad, India (Teaching hospital



of the J. S. Ayurved College).

prostatic enlargement in men.

Criteria for inclusion





Positive

patient’s

history

and

Rectal examination was done for

Genital examination was done in

female for cystocele or rectocele or mucosal

established diagnosis of incontinence of

atrophy of vagina.

urine due to age related changes.





examination was done for UTI or other

Patients having 60 and above 60

Urine

routine

&

microscopic

years of age.

disorders.

Criteria for exclusion

Study protocol and timelines



Patients with notable diseases like

Patients were treated in both OPD and IPD.

UTI,

prostate

cystocele,

Total 15 patients with incontinence of urine

vaginal prolapse, other neurogenic organic

were screened and all the patients’ data sets

diseases like multiple sclerosis, stroke,

were completely recorded.

motor

has

The main assessment period was 1 month.

prostatectomy done were excluded from the

Patients were advised to continue all

study.

Āyurvedic medicaments except Abhyanga,



neurone

enlargement,

diseases

etc

and

Patients having associated diseases

baspasvedana and matrabasti during the

like diabetes mellitus, cerebral vascular

follow-up period. Follow-up was done with

stroke were also excluded.

all patients for a period of next 2 months.

Criteria for diagnosis

During follow-up, patients were observed

________________________________________________________________________________________________________ Patel et al. 2017 Greentree Group © IJAPC Int J Ayu Pharm Chem 2017 Vol. 7 Issue 1 www.ijapc.com 313 [e ISSN 2350-0204]

Int J Ayu Pharm Chem

clinically for signs and symptoms every 15

two times in the morning and evening with

days.

milk.

Therapy

Diet: During main assessment period and

All patients were treated with:

follow-up period, patients were kept on rice,

A.

boiled mung, mung beans soup, boiled

Abhyanga (whole body massage)

with narayana oil followed by baspa

vegetables,

svedana (whole body steam bath) with

chapattis. Sour tasty foods, chilies, all other

nirgundi patra (leaf of vitex nigundo) one

beans except mung and other food which

time daily in the morning.

heavy to digest were restricted.

B.

Preparation of medicines

Daily matra basti (procto-colonic

khichadi,

and

wheat

flour

administration of medicated oil) of 40 ml

Āyurvedic medicines were prepared under

narayana oil15 after the dinner.

expert supervision strictly adhering to

C.

Kegel excercise16 (special exercise)

standard operating procedures (SOP) at

daily in the morning and evening at empty

Sunder Āyurved Pharmacy.

stomach.

Assessment of the results

D.



Oral medicine: Balamoola (root of

Patients’ improvement was assessed

abutilon indicum) kvath (decoction) 40 ml

based on the relief in clinical signs and

twice in the morning and evening after the

symptoms of the disease. All signs and

food. Narayana oil 20 ml twice with

symptoms were graded before and after the

Balamoola kvath. Ashvagandha (root of the

treatment. (see table 1)

withenia somnifera) churna (powder) 3 gm Table 1 Assessment criteria of signs and symptoms Signs and symptoms 0 1 Incontinence of urine No incontinence Incontinence during maximum stressful condition like coughing sneezing etc

2 Incontinence during medium stressful condition like walking

Assessment of urgency (Ability to hold the urine)

1 minutes or more but less than 2 minutes



3 minutes or more

2 minutes or more but less than 3 minutes

3 Incontinence without any stressful condition like sleeping or rest period Less than 1 minutes

Daily activities affected due to

The score of each and every question was

incontinence of urine were also assessed

recorded at before and after the treatment

according

and also analyzed using the t- test.

to

the

King’s

Health

Questionnaire for incontinence of urine.17 ________________________________________________________________________________________________________ Patel et al. 2017 Greentree Group © IJAPC Int J Ayu Pharm Chem 2017 Vol. 7 Issue 1 www.ijapc.com 314 [e ISSN 2350-0204]

Int J Ayu Pharm Chem



All

outcomes

were

statistically

> 0.05 = Insignificant result; P < 0.01 =

analyzed using a t-test. Statistical analysis –

significant result.

Mean score (X), Standard deviation (S.D.),



Standard error (S.E.), t - test were carried

and symptoms (if existent) and were

out at the level of 0.05, 0.01, 0.001 of p

performed every 15 days.

During follow-up we recorded signs

value. Then the results were interpreted as P

RESULTS AND DISCUSSION In this study 15 patients of Urinary

75% of the patients were suffered social and

incontinence

family problems due to incontinence.

completed

the

course

of

treatment. Maximum number of the patients

Table 2 and 3 show the results of the study.

(60%) was more than 69 years of age,

Improvement

female 66.66%, Hindus 81%, Muslim 2

incontinence of urine was 66.66% which is

patients and 60% were belonged in middle

statistically

class society. All the patients were married.

urgency was decreased by 57.14% which is

in

highly

the

symptom

significant.

of

Urine

also statistically highly significant. Table 2 Effect on signs and symptoms Signs and symptoms Mean value Before treatment Incontinence of urine 2.4 ± 0.63 Urine urgency 2.3 ± 0.61

After treatment 0.8 ± 0.67 1.0 ± 1.0

Improvement in percent (%)

t-value

p-value

66.66 ± 0.63 57.14 ± 0.62

9.79 8.66

< 0.001 < 0.001

Table 3 Effect on King’s Health Questionnaire of urinary incontinence King's Health Mean score Improvement in Questionnaire percent (%) Before treatment After treatment

t-value

P-value

General Health

58.3 ± 11.8

28.3 ± 11.6

51.43 ± 8.89

13.06

< 0.001

Incontinence impact

53.28 ± 16.31

17.8 ± 16.6

66.67 ± 8.31

16.56

< 0.001

Role limitations

52.17 ± 18.11

23.28 ± 8.18

55.38 ± 12.84

8.71

< 0.001

Physical limitations

53.28 ± 19.43

23.28 ± 14.66

56.31 ± 13.87

8.37

< 0.001

Social limitations

35.13 ± 16.44

16.63 ± 13.59

52.66 ± 8.53

8.4

< 0.001

Personal relationship

23.28 ± 8.18

7.75 ± 8.28

66.72 ± 4.15

14.49

< 0.001

Emotions

39.96 ± 13.32

18.87 ± 11.06

52.79 ± 9.54

8.55

< 0.001

Sleep / Energy

31.07 ± 10.32

9.96 ± 8.13

67.95 ± 7.38

11.08

< 0.001

Severity measures

31.09 ± 12.34

18.84 ± 10.74

39.41 ± 7.34

6.46

< 0.001

All the results related to the King’s Health

significant. General health and incontinence

Questionnaire

impact were decreased by 51.43% and

were

also

statistically

________________________________________________________________________________________________________ Patel et al. 2017 Greentree Group © IJAPC Int J Ayu Pharm Chem 2017 Vol. 7 Issue 1 www.ijapc.com 315 [e ISSN 2350-0204]

Int J Ayu Pharm Chem

66.67% respectively. Limitations in daily

Matrabasti is a form of Sneha Basti.

activities like role imitations, physical

Matrabasti nourishes the body, promotes the

limitations,

personal

strength, and cures Vata-related diseases.19

relationship, emotional disturbances and

Basti, through its action on Vata and Agni,

sleep / energy problems were also decreased

promotes the formation of Dhatus. The

by 52.17%, 53.28%, 35.13%, 23.28%,

colon is considered as main seat of Vata,

39.96% and 31.07% respectively. A disease

and

severity measure according to the patients’

administered through the rectocolonic route

knowledge was also decreased by 31.09%.

in Matrabasti are able to have their optimum

During follow-up period no any other signs

effect on the seat of Vata. Taila (sesame oil)

or symptoms related to the disease was

itself is a potent Vata-alleviating substance.

found. Moreover the signs and symptoms

Its Vatashamaka action is enhanced when it

also improved in the follow-up period. The

is processed with Vatashamaka drugs like

daily activities were also improved. No any

Patala (Stereospermum suaveolens DC.),

types of unwanted effect noted during the

Ashvagandha (Withania somnnifera Dunal.),

trial and follow-up period.

Agnimantha (Clerodendrum phlomidis Linn.

social

limitations,

Vata-alleviating

substances

f.), bala (Abutilon indicum Linn.), and the

DISCUSSION

like,

in

preparing

Such patients when treated with this therapy

Narayanaa

showed good response. The result obtained

through

may be attributed to the disease modifying

Balamoola and Ashvagandha are also useful

effect of trial therapy by means of their anti

for rasayana karma which helps to prevent

vata properties. Vajroli mudra would help

and cure the age related diseases.21-24 Kegel

them to remove the over activity of the

excercise helps to improve the stability and

detrusor muscles by giving the strength of

activity of detrusor and other pelvic floor

bladder and other pelvic floor muscles. No

muscles. Kegel exercise is most similar to

any unwanted features noted during the

vajroli mudra and ashvini mudra of yoga

assessment as well as follow-up period.

science.

taila

any

can

route

Narayanaa be in

Taila.

administered Vata

Roga.20

Balamoola kvatha and narayana taila have vata shamaka properties and so it lead to

CONCLUSION

cure the vata dominancy in the disease.18 ________________________________________________________________________________________________________ Patel et al. 2017 Greentree Group © IJAPC Int J Ayu Pharm Chem 2017 Vol. 7 Issue 1 www.ijapc.com 316 [e ISSN 2350-0204]

Int J Ayu Pharm Chem

On the basis of our clinical observations and the results made, it may be concluded that the Urinary incontinence found in elder people having more than 60 years of age is due to over activity of the detrusor muscle. In old age Vata is more dominant in the patients and therefore this reason is found to create this disorder. The trial therapy is an ideal drug as a safe alternative in cases of urinary incontinence in elder people. Hence symptomatic relief will get all the types of cases of the incontinence of the urine in elderly. CONFLICT OF INTEREST Nil

________________________________________________________________________________________________________ Patel et al. 2017 Greentree Group © IJAPC Int J Ayu Pharm Chem 2017 Vol. 7 Issue 1 www.ijapc.com 317 [e ISSN 2350-0204]

Int J Ayu Pharm Chem

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