Br OH O Br OH Br OH NBS, hν allylic bromination Br bromide to ... - ASU [PDF]

allylic bromination. Br bromide to alkene, E2 elimination with bulky base bulky base and 3° halide gives least substitu

0 downloads 3 Views 51KB Size

Recommend Stories


br
You miss 100% of the shots you don’t take. Wayne Gretzky

BR ITL AND BR IT BR ITL AL AND BR ITL AND L AND BR ITL BR ITL
I cannot do all the good that the world needs, but the world needs all the good that I can do. Jana

AIMS Br
Learning never exhausts the mind. Leonardo da Vinci

GGT BR
Be grateful for whoever comes, because each has been sent as a guide from beyond. Rumi

BR McConnon
How wonderful it is that nobody need wait a single moment before starting to improve the world. Anne

BR-9543A
Come let us be friends for once. Let us make life easy on us. Let us be loved ones and lovers. The earth

BR-0240
Come let us be friends for once. Let us make life easy on us. Let us be loved ones and lovers. The earth

Br. EHY3000_E_R.indd
Sorrow prepares you for joy. It violently sweeps everything out of your house, so that new joy can find

Brazil (BR)
Be grateful for whoever comes, because each has been sent as a guide from beyond. Rumi

GGT BR
Nothing in nature is unbeautiful. Alfred, Lord Tennyson

Idea Transcript


Basic Functional Group Interconversions (FGI) NBS, hν Br bromination of an alkane NBS, hν

Br

allylic bromination

+– Br K O-t-Bu

bromide to alkene, E2 elimination with bulky base

Br K+ –O-t-Bu

bulky base and 3° halide gives least substituted alkene

Br Na+ –OH

Br

simple base and 3° halide gives most substituted alkene

Na+ –OH

OH

1. Hg(OAc)2/H2O

bromide to alcohol, simple SN2

Br Br2 addition to an alkene Br

1. BH3.THF

OH

2. –OH/H2O2 HBr

Br O

MCPBA Na/NH3(l)

OH

OH

alkene to anti-Markovnikov bromide alkene to epoxide alkyne to trans-alkene

H2/Lindlar

OH

alkene to anti-Markovnikov alcohol alkene to Markovnikov bromide

Br

HBr/ROOR

OH

alkene to Markovnikov alcohol

OH

2. NaBH4/EtOH Br2

alkyne to cis-alkene Br

PBr3

alcohol to bromide

conc. H2SO4 PCC Na2Cr2O7 H2SO4

alcohol to alkene H O

alcohol to aldehyde

O OH

alcohol to carboxylic acid

Br Br 1. Excess NaNH /heat 2 CH3 C CH CH3 CH CH2 2. H2O O

NaBH4 EtOH

OH

formation of an alkyne (±)

reduction of aldehydes/ketones

Smile Life

When life gives you a hundred reasons to cry, show life that you have a thousand reasons to smile

Get in touch

© Copyright 2015 - 2024 PDFFOX.COM - All rights reserved.