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cardiomyopathy
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Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the Cardiac muscle itself. Cardiomyopathies are classified according to their predominant pathophysiological features (Dilated cardiomyopathy; Hypertrophic cardiomyopathy; Restrictive cardiomyopathy) or their etiological/pathological factors (Cardiomyopathy, Alcoholic; Endocardial fibroelastosis).
A Mouse 5/6th Nephrectomy Model That Induces Experimental Uremic Cardiomyopathy
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Xiaoliang Wang*1, Muhammad A. Chaudhry*2, Ying Nie2, Zijian Xie1, Joseph I. Shapiro2, Jiang Liu1,2 1Marshall Institute for Interdisciplinary Research (MIIR), Marshall University, 2Department of
Biomedical Sciences, Marshall University Joan C. Edwards School of Medicine
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F IL T ER BY JOURNAL SECT ION
B IOLOGY
Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients.
F IL T ER BY SCIENCE EDUCAT ION
Chiara Assunta Pilato*1,2, Ilaria Stadiotti*1, Angela Serena Maione1, Valentina Saverio1, Valentina Catto3, Fabrizio Tundo3, Antonio Dello Russo3, Claudio Tondo2,3, Giulio Pompilio1,2, Michela Casella3, Elena Sommariva1
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1Vascular Biology and Regenerative Medicine Unit, Centro Cardiologico Monzino-IRCCS, 2Department of Clinical Sciences and Community Health, Università degli Studi di Milano, 3Heart
Rhythm Center, Centro Cardiologico Monzino-IRCCS
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Isolation and Functional Characterization of Human Ventricular Cardiomyocytes from Fresh Surgical Samples Raffaele Coppini1, Cecila Ferrantini2, Alessandro Aiazzi2, Luca Mazzoni1, Laura Sartiani1, Alessandro Mugelli1, Corrado Poggesi2, Elisabetta Cerbai1 1Department NeuroFarBa, Division of Pharmacology, University of Florence, 2Department of
Clinical and Experimental Medicine, Division of Physiology, University of Florence MED IC IN E
Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix Matthew K. Stephenson1, Sean Lenihan2,3, Roman Covarrubias2,3, Ryan M. Huttinger2,3, Richard J. Gumina2,3, Douglas B. Sawyer4, Cristi L. Galindo2,3 1Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, 2Department of Medicine, Vanderbilt University Medical Center, 3Division of Cardiovascular
Medicine, Vanderbilt University Medical Center, 4Cardiovascular Institute, Maine Medical Center B IOLOGY
Generation of Induced Pluripotent Stem Cells from Muscular Dystrophy Patients: Efficient Integration-free Reprogramming of Urine Derived Cells Muhammad Z. Afzal1, Jennifer L. Strande1 1Department of Medicine, Medical College of Wisconsin
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Cardiac Exam III: Abnormal Heart Sounds Source: Suneel Dhand, MD, Attending Physician, Internal Medicine, Beth Israel Deaconess Medical Center Having a fundamental understanding of normal heart sounds is the first step toward distinguishing the normal from the abnormal. Murmurs are sounds that represent turbulent and abnormal blood flow across a heart valve. They are caused either by… PH YSIC A L EXA MIN A TION S I
Analysis of Tubular Membrane Networks in Cardiac Myocytes from Atria and Ventricles Eva Wagner*1,2,3, Sören Brandenburg*1,2, Tobias Kohl1,2, Stephan E. Lehnart1,2,3,4 1Heart Research Center Goettingen, 2Clinic of Cardiology & Pulmonology, University Medical
Center Goettingen, 3German Center for Cardiovascular Research (DZHK) partner site Goettingen, 4BioMET, Center for Biomedical Engineering & Technology, University of Maryland School of Medicine B IOEN GIN EER IN G
Measurement of Antibody Effects on Cellular Function of Isolated Cardiomyocytes Lars G. Eckerle1, Stephan B. Felix1, Lars R. Herda1 1Department of Internal Medicine B, University Medicine Greifswald
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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing Jingfeng Wang*1, Zhenning Nie*1, Haiyan Chen*2, Xianhong Shu2, Zhaohua Yang3, Ruiming Yao1, Yangang Su1, Junbo Ge1 1Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital,
Fudan University, 2Department of Echocardiography, Shanghai Institute of Medical imaging, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, 3Department of Cardiac surgery, Shanghai Institute of Cardiovascular Diseases, Zhongshan
Hospital, Fudan University B IOLOGY
Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR Lik Chuan Lee1, Zhang Zhihong1, Andrew Hinson2, Julius M. Guccione1 1Department of Surgery, UCSF/VA Medical Center, 2Clinical & Regulatory, LoneStar Heart, Inc.
MED IC IN E
Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery Laura Hocum Stone1, Christin Wright1, Erin Chappuis1, Mia Messer1, Herbert B. Ward1, Edward O. McFalls2, Rosemary F. Kelly1
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1Department of Surgery, University of Minnesota, 2Cardiology, Minneapolis VA Medical Center
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Ultrasound-guided Transthoracic Intramyocardial Injection in Mice Terence W. Prendiville1, Qing Ma1, Zhiqiang Lin1, Pingzhu Zhou1, Aibin He1, William T. Pu1,2 1Department of Cardiology, Boston Children's Hospital, 2Harvard Stem Cell Institute, Harvard
University MED IC IN E
Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle Vidhya Kumar1, Henry Chang1, David A. Reiter2, David P. Bradley3, Martha Belury4, Shana E. McCormack5, Subha V. Raman1 1Davis Heart and Lung Research Institute, The Ohio State University, 2Laboratory of Clinical
Investigation, National Institute on Aging, 3Division of Endocrinology, Diabetes and Metabolism, The Ohio State University, 4Department of Human Sciences, Human Nutrition, The Ohio State University, 5Division of Endocrinology and Diabetes, Department of Pediatrics, University of Pennsylvania MED IC IN E
Measuring Pressure Volume Loops in the Mouse DeWayne Townsend1 1Department of Integrative Biology and Physiology, University of Minnesota
B IOLOGY
Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model Antonio R. L. Teixeira1, Nadjar Nitz1, Francisco M. Bernal1, Mariana M. Hecht1 1Chagas Disease Multidisciplinary Research Laboratory, University of Brasilia
IMMU N OLOGY A N D IN FEC TION
High Fat Diet Feeding and High Throughput Triacylglyceride Assay in Drosophila Melanogaster Soda Balla Diop1, Ryan T. Birse1, Rolf Bodmer1 1Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery
Institute GEN ETIC S
Creating a Structurally Realistic Finite Element Geometric Model of a Cardiomyocyte to Study the Role of Cellular Architecture in Cardiomyocyte Systems Biology Vijay Rajagopal1,2,3, Gregory Bass2,3, Shouryadipta Ghosh1,2, Cameron G. Walker4, Eric Hanssen5, Edmund J. Crampin2,3,6,7,8, Christian Soeller9
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1Cell Structure and Mechanobiology Group, Department of Biomedical Engineering, University of
Melbourne, 2Systems Biology Laboratory, Melbourne School of Engineering, University of Melbourne, 3Department of Biomedical Engineering, University of Melbourne, 4Department of Engineering Science, University of Auckland, 5Advanced Microscopy Facility, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, 6School of Medicine, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, 7School of Mathematics and Statistics, Faculty of Science, University of Melbourne, 8ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, University of Melbourne, 9Living Systems Institute, University of Exeter J oVE IN -PR ESS
Ultrasonic Assessment of Myocardial Microstructure Pranoti Hiremath1, Michael Bauer2, Hui-Wen Cheng2, Kazumasa Unno2, Ronglih Liao2, Susan Cheng2 1Harvard Medical School, 2Cardiovascular Division, Department of Medicine, Brigham and
Women's Hospital, Harvard Medical School MED IC IN E
A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice Hao Chen1, Jessica N. Perez1, Eleni Constantopoulos1, Laurel McKee1, Jessica Regan1, Patricia B. Hoyer1, Heddwen L. Brooks1, John Konhilas1 1Department of Physiology, University of Arizona
MED IC IN E
Construction of Defined Human Engineered Cardiac Tissues to Study Mechanisms of Cardiac Cell Therapy Timothy J. Cashman1, Rebecca Josowitz2, Bruce D. Gelb2, Ronald A. Li1,3, Nicole C. Dubois2, Kevin D. Costa1 1Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, 2The Mindich Child
Health and Development Institute, Icahn School of Medicine at Mount Sinai, 3Stem Cell & Regenerative Medicine Consortium, LKS Faculty of Medicine, University of Hong Kong B IOEN GIN EER IN G
Skeletal Muscle Neurovascular Coupling, Oxidative Capacity, and Microvascular Function with 'one Stop Shop' Near-infrared Spectroscopy Ryan Rosenberry1, Susie Chung1, Michael D. Nelson1
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1Applied Physiology and Advanced Imaging Laboratory, Department of Kinesiology, University of
Texas at Arlington
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Implantation of the Syncardia Total Artificial Heart Daniel G. Tang1, Keyur B. Shah2, Micheal L. Hess2, Vigneshwar Kasirajan1 1Division of Cardiothoracic Surgery, Virginia Commonwealth University, 2Division of Cardiology,
Virginia Commonwealth University MED IC IN E
Automated Contraction Analysis of Human Engineered Heart Tissue for Cardiac Drug Safety Screening Ingra Mannhardt1, Umber Saleem 1, Anika Benzin1, Thomas Schulze1, Birgit Klampe1, Thomas Eschenhagen1, Arne Hansen1 1Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center,
University Medical Center Hamburg-Eppendorf and DZHK (German Center for Cardiovascular Research) B IOEN GIN EER IN G
Isolation and Physiological Analysis of Mouse Cardiomyocytes Gretchen M. Roth1, David M. Bader1,2, Elise R. Pfaltzgraff2 1Department of Medicine, Vanderbilt University, 2Department of Cell and Developmental Biology,
Vanderbilt University B IOLOGY
Isolation and Culture of Neonatal Mouse Cardiomyocytes Elisabeth Ehler1, Thomas Moore-Morris2, Stephan Lange2 1Randall and Cardiovascular Divisions, King’s College London, 2Division of Cardiology, School of
Medicine, University of California San Diego B IOLOGY
Simultaneous Assessment of Cardiomyocyte DNA Synthesis and Ploidy: A Method to Assist Quantification of Cardiomyocyte Regeneration and Turnover Gavin D. Richardson1 1Institute of Genetic Medicine, International Centre for Life, Newcastle University
D EVELOPMEN TA L B IOLOGY
Cardiac Pressure-Volume Loop Analysis Using Conductance Catheters in Mice Dennis Abraham 1, Lan Mao1 1Department of Medicine, Duke University Medical Center
B IOLOGY
Use of a Hanging Weight System for Coronary Artery Occlusion in Mice Tobias Eckle1, Michael Koeppen1, Holger Eltzschig1 1Department of Anesthesiology, University of Colorado Denver
MED IC IN E
Assessment of Sarcoplasmic Reticulum Calcium Reserve and Intracellular Diastolic Calcium Removal in Isolated Ventricular Cardiomyocytes Jing Gao*1, Xiaolu Shi*2, Hong He1, Juhong Zhang1, Ding Lin3, Guosheng Fu1, Dongwu Lai1 1Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 2Experimental Research Center, China Academy of Chinese Medical Sciences, 3Department of
Cardiology, The Third Hospital of Hangzhou City MED IC IN E
Fluorescent Labeling of Drosophila Heart Structures Nakissa N. Alayari1,2, Georg Vogler2, Ouarda Taghli-Lamallem 2, Karen Ocorr2, Rolf Bodmer2, Anthony Cammarato1,2 1Biology Department, San Diego State University, 2Development and Aging Program, NASCR
Center, The Sanford Burnham Institute for Medical Research B IOLOGY
Intramyocardial Cell Delivery: Observations in Murine Hearts Tommaso Poggioli1,2, Padmini Sarathchandra1,2, Nadia Rosenthal2,3, Maria P. Santini1,2 1Magdi Yacoub Institute, Imperial College London, 2National Heart and Lung Institute, Imperial
College London, 3Australian Regenerative Medicine Institute, Monash University MED IC IN E
Cardiac Catheterization in Mice to Measure the Pressure Volume Relationship: Investigating the Bowditch Effect Bo Zhang1,2, Jonathan P. Davis1, Mark T. Ziolo1 1Department of Physiology & Cell Biology, Davis Heart and Lung Research Institute, The Ohio State
University, 2Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology MED IC IN E
Generation of Human Cardiomyocytes: A Differentiation Protocol from Feederfree Human Induced Pluripotent Stem Cells Elisa Di Pasquale1,2, Belle Song1, Gianluigi Condorelli1 1Humanitas Clinical and Research Center, Italy, 2Institute of Genetic and Biomedical Research
(IRGB), National Research Council (CNR) B IOLOGY
Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure Ilayaraja Muthuramu1, Marleen Lox1, Frank Jacobs1, Bart De Geest1 1Department of Cardiovascular Sciences, Centre for Molecular and Vascular Biology, Catholic
University of Leuven MED IC IN E
Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse Chandirasegaran Massilamany*1, Vahid Khalilzad-Sharghi*2, Arunakumar Gangaplara1, David Steffen1, Shadi F. Othman2, Jay Reddy1 1School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, 2Department of Biological Systems Engineering, University of Nebraska-Lincoln
MED IC IN E
Assessing Autophagic Flux by Measuring LC3, p62, and LAMP1 Colocalization Using Multispectral Imaging Flow Cytometry Haley R. Pugsley1 1Amnis Biology Department, MilliporeSigma
B IOLOGY
Assessment of Myofilament Ca2+ Sensitivity Underlying Cardiac Excitationcontraction Coupling Zai Hao Zhao1, Chun Li Jin1, Ji Hyun Jang1, Yu Na Wu1, Sung Joon Kim 1, Hong Hua Jin2, Lan Cui2, Yin Hua Zhang1,2,3 1Department of Physiology & Biomedical Sciences, Ischemic/hypoxic Disease Institute, Seoul
National University College of Medicine, 2Yan Bian University Hospital, 3Institute of Cardiovascular Sciences, University of Manchester B IOLOGY
In Vitro Differentiation of Human Mesenchymal Stem Cells into Functional Cardiomyocyte-like Cells Peter Szaraz*1,2, Yarden S. Gratch*1, Farwah Iqbal1,2, Clifford L. Librach1,2,3,4,5 1Create Fertility Centre, 2Department of Physiology, University of Toronto, 3Department of
Obstetrics and Gynecology, University of Toronto, 4Department of Physiology, University of Toronto, 5Department of Obstetrics and Gynecology, Women's College Hospital D EVELOPMEN TA L B IOLOGY
Scalable 96-well Plate Based iPSC Culture and Production Using a Robotic Liquid Handling System Michael K. Conway1, Michael J. Gerger1, Erin E. Balay1, Rachel O'Connell1, Seth Hanson2, Neil J. Daily1, Tetsuro Wakatsuki1 1InvivoSciences, Inc., 2Gilson, Inc.
D EVELOPMEN TA L B IOLOGY
Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice Grace Casaclang-Verzosa1, Maurice Enriquez-Sarano2, Hector R. Villaraga2, Jordan D. Miller1,3 1Department of Surgery, Mayo Clinic, 2Department of Medicine, Mayo Clinic, 3Department of
Physiology & Biomedical Engineering, Mayo Clinic MED IC IN E
Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein Shubhendu Sen Roy1, Huy Cong Xuan Nguyen1, Thomas A. Angelovich2,3, Anna C. Hearps2, Diana Huynh1,4, Anthony Jaworowski2,4, Theodoros Kelesidis1 1University of California, Los Angeles, 2Centre for Biomedical Research, Burnet Institute, 3School of Health and Biomedical Sciences, RMIT University, 4Department of Infectious Diseases,
Monash University IMMU N OLOGY A N D IN FEC TION
Detecting Anastasis In Vivo by CaspaseTracker Biosensor Ho Man Tang1, Ming Chiu Fung2, Ho Lam Tang3
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1Institute for Basic Biomedical Sciences, Johns Hopkins University School of Medicine, 2School
of Life Sciences, Chinese University of Hong Kong, 3Department of Neurosurgery, Johns Hopkins University School of Medicine
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Analysis of Protein-protein Interactions and Co-localization Between Components of Gap, Tight, and Adherens Junctions in Murine Mammary Glands Elham Dianati1,2, Isabelle Plante1 1INRS, Institut Armand-Frappier, 2Biomed, UQAM
D EVELOPMEN TA L B IOLOGY
Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-Encoded Fluorogenic Sensors Elizabeth M. Corteselli1, James M. Samet2, Eugene Gibbs-Flournoy3
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1Department of Environmental Sciences and Engineering, Gillings School of Global Public Health,
University of North Carolina at Chapel Hill, 2Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, 3Oak Ridge Institute for Science and Education J oVE IN -PR ESS
MitoCeption: Transferring Isolated Human MSC Mitochondria to Glioblastoma Stem Cells Brice Nzigou Mombo1, Sabine Gerbal-Chaloin1, Aleksandra Bokus1, Martine Daujat-Chavanieu1, Christian Jorgensen1, Jean-Philippe Hugnot2, Marie-Luce Vignais1 1Institute for Regenerative Medicine and Biotherapy (IRMB), INSERM U1183, Montpellier
University, 2Institute of Neurosciences of Montpellier (INM), INSERM U1051, Montpellier University B IOLOGY
Analysis of Cardiomyocyte Development using Immunofluorescence in Embryonic Mouse Heart Lisa D. Wilsbacher1,2, Shaun R. Coughlin2 1Feinberg Cardiovascular Research Institute, Northwestern University, 2Cardiovascular Research
Institute, University of California, San Francisco D EVELOPMEN TA L B IOLOGY
Drosophila Preparation and Longitudinal Imaging of Heart Function In Vivo Using Optical Coherence Microscopy (OCM) Jing Men1,2, Jason Jerwick2,3, Penghe Wu1,2, Mingming Chen3,4, Aneesh Alex2,3, Yutao Ma4, Rudolph E. Tanzi5, Airong Li5, Chao Zhou1,2,3 1Bioengineering Program, Lehigh University, 2Center for Photonics and Nanoelectronics, Lehigh
University, 3Department of Electrical and Computer Engineering, Lehigh University, 4State Key Laboratory of Software Engineering, Wuhan University, 5Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School B IOLOGY
A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology Dominique Tremblay1, Charles M. Cuerrier1,2, Lukasz Andrzejewski1, Edward R. O'Brien3, Andrew E. Pelling1,4,5 1Centre for Interdisciplinary NanoPhysics, Department of Physics, University of Ottawa, 2University
of Ottawa Heart Institue, University of Ottawa, 3Libin Cardiovascular Institute of Alberta, University of Calgary, 4Department of Biology, University of Ottawa, 5Institute for Science, Society and Policy, University of Ottawa B IOEN GIN EER IN G
Establishing a Multidisciplinary Cavernous Carotid Injury Simulation to Train Neurosurgical, Otolaryngology, and Anesthesia Residents Brandon Lucke-Wold1, Haley E. Gillham 2, Mark Baskerville2, William E. Cameron2, Dawn Dillman2, Caleb A. Haley2, Michele Noles2, Donn Spight2, Jeremy N. Ciporen2
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1West Virginia University School of Medicine, 2Oregon Health & Science University
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In Situ Detection of Autoreactive CD4 T Cells in Brain and Heart Using Major Histocompatibility Complex Class II Dextramers Chandirasegaran Massilamany1, Arunakumar Gangaplara1, Ting Jia1, Christian Elowsky2, Qingsheng Li3, You Zhou2, Jay Reddy1 1School of Veterinary Medicine and Biomedical Sciences, University of Nebraska, Lincoln, 2Center for Biotechnology, University of Nebraska, Lincoln, 3Nebraska Center for Virology and
School of Biological Sciences, University of Nebraska, Lincoln IMMU N OLOGY A N D IN FEC TION
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