Chagas disease: Current perspectives on a forgotten disease [PDF]

Oct 19, 2016 - However, it is known that there is damage to the autonomic nervous system which results in abnormalities

3 downloads 14 Views 40KB Size

Recommend Stories


Chagas Disease
So many books, so little time. Frank Zappa

Current status and perspectives of cell therapy in Chagas disease
Never let your sense of morals prevent you from doing what is right. Isaac Asimov

Chagas disease-specific antigens
Nothing in nature is unbeautiful. Alfred, Lord Tennyson

Pathogenesis of Chagas' Disease
What we think, what we become. Buddha

Chagas Disease and Transfusion Transmission
Forget safety. Live where you fear to live. Destroy your reputation. Be notorious. Rumi

Sudden Death in Chagas' Disease
Sorrow prepares you for joy. It violently sweeps everything out of your house, so that new joy can find

Control measures for Chagas disease
It always seems impossible until it is done. Nelson Mandela

a retrospective analysis of Chagas disease com
Suffering is a gift. In it is hidden mercy. Rumi

Current Perspectives on Interoperability
The beauty of a living thing is not the atoms that go into it, but the way those atoms are put together.

American trypanosomiasis, or Chagas disease, in Panama
Your big opportunity may be right where you are now. Napoleon Hill

Idea Transcript


Journals

Download

Books

Register

Sign in

Export

Revista Médica del Hospital General de México Available online 19 October 2016 open access In Press, Corrected Proof Review article

Chagas disease: Current perspectives on a forgotten disease Enfermedad de Chagas: Perspectivas actuales sobre una enfermedad olvidada D.-A. Álvarez-Hernández a, b

, G.-A. Franyuti-Kelly a, R. Díaz-López-Silva c , A.-M. González-Chávez d, e, D. González-Hermosillo-Cornejo d, f, R. Vázquez-López g

Show more https://doi.org/10.1016/j.hgmx.2016.09.010

Get rights and content

Open Access funded by Sociedad Médica del Hospital General de México Under a Creative Commons license

Abstract Chagas disease is a parasitic zoonosis caused by Trypanosoma cruzi, a protozoan whose transmission to humans is primarily vector-borne. It is estimated that 6–8 million people worldwide are infected and that 65–100 million people are at risk of becoming infected. Its clinical spectrum is very broad. During the acute phase, non-specific manifestations develop that may go unnoticed. During the chronic phase, specific manifestations develop that are diagnosed late and increase the morbidity and mortality of those suffering from it. The drugs available to treat it are partially effective, and the efforts made to develop a vaccine remain insufficient. This article reviews the most significant aspects of Chagas disease, from the discovery of the disease to the development of a vaccine, to help train general practitioners and specialists to provide timely care to those suffering from the disease.

Resumen La enfermedad de Chagas es una zoonosis parasitaria causada por Trypanosoma cruzi, un protozoario que se transmite principalmente de manera vectorial al ser humano. Se estima que entre 6-8 millones de personas alrededor del mundo se encuentran infectadas y que entre 65-100 millones están en riesgo de infectarse. Su espectro clínico es muy amplio, pudiendo desarrollar manifestaciones inespecíficas durante la fase aguda que pueden pasar desapercibidas y manifestaciones especificas durante la fase crónica que se diagnostican tardíamente e incrementan la morbimortalidad de quienes la padecen. Los medicamentos disponibles para su tratamiento son parcialmente eficaces y los esfuerzos para crear una vacuna aún continúan siendo insuficientes. En este artículo revisamos los aspectos más relevantes de la enfermedad de Chagas desde su descubrimiento hasta la vacuna, con el objetivo de contribuir en la preparación de médicos generales y especialistas para que proporcionen atención oportuna a quienes la padezcan.

Keywords American trypanosomiasis; Chagas disease; Neglected tropical diseases; Triatomines; Trypanosoma cruzi

Palabras clave Tripanosomiasis Americana; Enfermedad de Chagas; Enfermedades tropicales desatendidas; Triatominos; Trypanosoma cruzi

Recommended articles

Citing articles (0)

© 2016 Sociedad Médica del Hospital General de México. Published by Masson Doyma México S.A.

About ScienceDirect

Remote access

Shopping cart

Contact and support

Terms and conditions

Privacy policy

Cookies are used by this site. For more information, visit the cookies page. Copyright © 2018 Elsevier B.V. or its licensors or contributors. ScienceDirect ® is a registered trademark of Elsevier B.V.

Smile Life

When life gives you a hundred reasons to cry, show life that you have a thousand reasons to smile

Get in touch

© Copyright 2015 - 2024 PDFFOX.COM - All rights reserved.