Idea Transcript
ORIGINAL ARTICLE
Clinical Profile of Extrapulmonary Tuberculosis Among TB-HIV Patients in Cipto Mangunkusumo Hospital Gurmeet Singh1, Anna Uyainah1, Evy Yunihastuti2, Darma Imran3
1
Division of Respirology and Critical Care, Department of Internal Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia. 2 Division of Clinical Allergy Immunology, Department of Internal Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia. 3 Division of Neuroinfection, Department Neurology, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
ABSTRACT
Background: In view of increase in incidence of EPTB after the epidemic of human immunodeficiency (HIV) virus infection, the clinical profile of EPTB in patients with HIV infection was studied. Objective: To obtain the profile and to assess the distribution of EPTB in TB-HIV patients. Methods: We conducted a descriptive cross-sectional study by browsing through the medical records of TB-HIV patients who received treatment in HIV referral center (POKDISUS) Cipto Mangunkusumo Hospital between July 2008-December 2010. Ethical clearance was obtained from the ethical committee of Faculty Medicine, Universitas Indonesia and written on approval letter 135/PT02.FK/ETIK2010. Results: EPTB prevalence was 32,95%. Overall, medical record of 522 HIV-positive TB patients were evaluated. The majority of the patients were males (84.3%), 18-40 years age group (91.9%), finished mid-level education (77.3%), and 31.4% belonged to Batavian ethnic group. Intravenous drug use were found to be the main transmission risk factor, representing 60.5% of the subjects. Prolonged fever (63.4%) was the most common clinical manifestation. Negative Acid Fast Baciili (AFB) smears were found in 34.9% of the subjects, while CD4+ counts of 200 cells/mm3)21. A BMI of