CT of Gastrointestinal Complications Associated with Hematopoietic [PDF]

Sternberg SS, Carter D, Oberman HA, Mills SE, Stoler MH. Sternberg's diagnostic surgical pathology, 4th ed., vol. 2New Y

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LOGIN Help Contact Alerts Home American Journal of Roentgenology Diagnostic Imaging and Related Sciences Published by Advanced Search Current Issue All Issues Collections Information For Authors Subscribers Members Reviewers Permissions About Search AJR

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Home > American Journal of Roentgenology > Volume 190, Issue 3 > CT of Gastrointestinal Complications Associated with Hematopoietic Stem Cell Transplantation

March 2008, Volume 190, Number 3 « Previous Article | Next Article »

Gastrointestinal Imaging Pictorial Essay

CT of Gastrointestinal Complications Associated with Hematopoietic Stem Cell Transplantation March 2008, VOLUME 190 NUMBER 3

Marc Schmit1 , Wolfgang Bethge2 , Robert Beck3 , Christoph Faul2 , Claus D. Claussen1 and Marius Horger1 Show less ... Show all Share + Affiliations:

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1 Department of Diagnostic Radiology, Eberhard-Karls-University, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany.

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2 Department of Internal Medicine II-Hematology/Oncology, Eberhard-Karls-University, Tübingen, Germany.

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3 Institute of Medical Virology, Eberhard-Karls-University, Tübingen, Germany.

Citation: American Journal of Roentgenology. 2008;190: 712-719. 10.2214/AJR.07.2628

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By keyword gastrointestinal complications hematopoietic stem cell ABSTRACT : transplantation OBJECTIVE. This article illustrates the characteristic CT findings of bowel damage related to drug toxicity, conditioning regimen, infections, and By author graft-versus-host disease (GVHD) in patients after hematopoietic stem cell transplantation. Marc Schmit CONCLUSION. Although some overlap exists in the CT appearances of the different causes of bowel wall inflammation, the findings are frequently Wolfgang Bethge unique enough to suggest a specific diagnosis. Awareness of the specific time of occurrence, intensity of clinical symptoms, preferred localization, and Claus D. Claussen extent of accompanying extraintestinal findings help to distinguish the different pathologic entities. Marius Horger Robert Beck Keywords: gastrointestinal complications, hematopoietic stem cell transplantation Christoph Faul Search in AJR Google Scholar Search

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Address correspondence to M. Horger ([email protected]). References

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1. Blijlevens NMA, Donnelly JP, De Pauw BE. Mucosal barrier injury: biology, pathology, clinical counterparts and consequences of intensive treatment for haematological malignancy—an overview. Bone Marrow Transplant 2000; 25:1269 –1278 [Crossref] [Medline] 2. Wagner ML, Rosenberg HS, Fernbach DJ, Singleton EB. Typhlitis: a complication of leukemia in childhood. AJR 1970; 109:341 –350 [Abstract] 3. Sternberg SS, Carter D, Oberman HA, Mills SE, Stoler MH. Sternberg's diagnostic surgical pathology, 4th ed., vol. 2New York, NY: Lippincott Williams & Wilkins,2004 : 1510–1511 4. Kirkpatrick ID, Greenberg HM. Gastrointestinal complications in the neutropenic patient: characterization and differentiation with abdominal CT. Radiology 2003; 226:668–674 [Crossref] [Medline] 5. Horton KM, Corl FM, Fishman EK. CT evaluation of the colon: inflammatory disease. Radio-Graphics 2000; 20:399 –418 6. Benya EC, Sivit CJ, Quinones RR. Abdominal complications after bone marrow transplantation in children: sonographic and CT findings. AJR 1993; 161:1023 –1027 [Abstract] 7. Levine DS, Navarro OM, Chaudry G, Doyle JJ, Blaser SI. Imaging the complications of bone marrow transplantation in children. RadioGraphics 2007; 27:307–324 [Crossref] [Medline] 8. Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL. Harrison's principles of internal medicine, 16th ed. New York, NY: McGraw Hill Medical Publishing Division, 2004:668 –673 9. Donnelly LF, Morris CL. Acute graft-vs.-host disease in children: abdominal CT findings. Radiology 1996; 198:1–9 [Crossref] [Medline] 10. Coy DL, Ormazabal A, Godwin JL, Lalani T. Imaging evaluation of pulmonary and abdominal complications following hematopoietic stem cell transplantation. RadioGraphics 2005; 25:305–317; discussion 318 [Crossref] [Medline] 11. Teixidor HA, Honig CL, Norsoph W, et al. Cytomegalovirus infection of the alimentary canal: radiologic findings with pathologic correlation. Radiology 1987; 163:317–323 [Medline]

12. Kingreen D, Nitsche A, Beyer J, Siegert W. Herpes simplex infection of the jejunum occurring in the early post-transplantation period. Bone Marrow Transplant 1997; 20:989–991 [Crossref] [Medline] 13. Symeonidis N, Jakubowski A, Pierre-Louis S, et al. Invasive adenoviral infections in T-cell-depleted allogeneic hematopoietic stem cell transplantation: high mortality in the era of cidofovir. Transpl Infect Dis 2007; 9:108 –113 [Crossref] [Medline] 14. Mohite U, Kell J, Haj MA, et al. Invasive aspergillosis localised to the colon presenting as toxic megacolon. Eur J Haematol 2007; 78:270 –273 [Crossref] [Medline] 15. Lee JH, Ha HK, Yoo E, Yang SK, Min YI, Auh YH. CT and sonographically guided biopsy in a patient with intestinal mucormycosis. AJR 2000; 175:129 –131 [Abstract]

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