final program - ECI 2015 [PDF]

FINAL PROGRAM

www.eci-vienna2015.org

Coordination ECI 2015 c/o WMA Ltd. Alser Strasse 4 • 1090 Vienna • Austria t: +43 1 405 13 83 16 f: +43 1 407 82 74 e: [email protected] www.eci-vienna2015.org Layout:

Barbara Biegl, www.biegl-grafik.at

Photo Credits:

Unless otherwise indicated all pictures © ECI – European Congress of Immunology

Copyright © 2015 ECI All rights reserved. No part of this publication may be reproduced, distributed or transmitted without the prior written permission of ECI. Some information may be subject to change.

CONGRESS INFORMATION Registration Information. . . . . . . . . . . . . . . . . . . . . . . . . . . . . Awards and Travel Grants . . . . . . . . . . . . . . . . . . . . . . . . . . . Floor Plans . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Opening Hours. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Congress Information A-Z. . . . . . . . . . . . . . . . . . . . . . . . . . . . ECI Social Media Guide. . . . . . . . . . . . . . . . . . . . . . . . . . . . . Information for Early Career Scientists . . . . . . . . . . . . . . . . . Information for Speakers and Poster Presenters. . . . . . . . . CME Accreditation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

12 13 18 20 20 24 24 25 26

SCIENTIFIC PROGRAM Program at a Glance. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 Session Type Description . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 Related Pre-Congressional Events in Vienna before the start of the 4th ECI Congress. . . . . . . . . . . . . . . . 40

SUNDAY Schedule at a Glance Sunday. . . . . . . . . . . . . . . . . . . . . . . Opening Ceremony. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Opening of Historic Exhibition “Emerging Immunology – Vienna’s Contribution” . . . . . . . Keynote Lecture of the Day . . . . . . . . . . . . . . . . . . . . . . . . . Educational Courses & Scientific Satellite Symposia . . . . . Business and Ancillary Meetings. . . . . . . . . . . . . . . . . . . . . .

42 43 43 44 44 44

MONDAY Schedule at a Glance Monday . . . . . . . . . . . . . . . . . . . . . . Keynote Lecture of the Day . . . . . . . . . . . . . . . . . . . . . . . . . Overview per Track. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Track A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Track B . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Track C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Track D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Joint-Symposia of the Day. . . . . . . . . . . . . . . . . . . . . . . . . . . Other Sessions and Meetings. . . . . . . . . . . . . . . . . . . . . . . . . Business and Ancillary Meetings. . . . . . . . . . . . . . . . . . . . . . Meet the Professor Breakfast. . . . . . . . . . . . . . . . . . . . . . . . . Posters of the Day according to Tracks A, B, C, D, E . . . . .

46 48 48 49 51 53 56 58 58 59 59 60

62 64 64 65 67 69 71 72 73 73 73 74 74

WEDNESDAY Schedule at a Glance Wednesday. . . . . . . . . . . . . . . . . . . Keynote Lecture of the Day . . . . . . . . . . . . . . . . . . . . . . . . . Overview per Track. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Track A . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Track B . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Track C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Track D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Track E . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Joint-Symposia of the Day. . . . . . . . . . . . . . . . . . . . . . . . . . . Other Sessions and Meetings. . . . . . . . . . . . . . . . . . . . . . . . . Educational Courses & Scientific Satellite Symposia . . . . . Business and Ancillary Meetings. . . . . . . . . . . . . . . . . . . . . . Meet the Professor Breakfast. . . . . . . . . . . . . . . . . . . . . . . . . Posters of the Day according to Tracks A, B, C, D, E . . . . . Closing and Award Ceremony. . . . . . . . . . . . . . . . . . . . . . .

76 78 78 79 81 84 85 87 87 88 88 88 88 89 89

Related Post Congressional Events in Vienna after 4th ECI . . . 90

INDUSTRY SPONSORED SYMPOSIA, SPONSORS AND EXHIBITORS Acknowledgements. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93 Sponsors’ Company Descriptions. . . . . . . . . . . . . . . . . . . . . 95 Industry Sponsored Symposia . . . . . . . . . . . . . . . . . . . . . . . . 97 Exhibition Information. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 Exhibition Floorplan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104

EFIS Info . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 108 Appointments with EFIS during the ECI 2015. . . . . . . . . . . 109 Upcoming Meetings (Sponsored by EFIS) . . . . . . . . . . . . . 109

NETWORKING EVENTS Networking Events. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112

THE CITY OF VIENNA The City of Vienna. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 114 Vienna City Map. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116 Vienna Public Transport Map . . . . . . . . . . . . . . . . . . . . . . . 118

www.eci-vienna2015.org

MONDAY

Addresses. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 About. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Committees. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9

Schedule at a Glance Tuesday. . . . . . . . . . . . . . . . . . . . . . Keynote Lecture of the Day . . . . . . . . . . . . . . . . . . . . . . . . . Overview per Track. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Track A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Track B . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Track C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Track D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Track E . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Joint-Symposia of the Day. . . . . . . . . . . . . . . . . . . . . . . . . . . Other Sessions and Meetings. . . . . . . . . . . . . . . . . . . . . . . . . Business and Ancillary Meetings. . . . . . . . . . . . . . . . . . . . . . Meet the Professor Breakfast. . . . . . . . . . . . . . . . . . . . . . . . . Posters of the Day according to Tracks A, B, C, D, E . . . . .

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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TUESDAY

ORGANIZATION

TUESDAY

WEDNESDAY

2 4 5 6

INDUSTRY / EXHIBITION

Welcome by the ECI Organizers. . . . . . . . . . . . . . . . . . . . . . . Welcome by the EFIS President. . . . . . . . . . . . . . . . . . . . . . . . Welcome in Austria. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Welcome in Vienna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

SUNDAY

TABLE OF CONTENTS

Welcomes

WELCOME BY THE ECI ORGANIZERS

Dear Colleagues and Friends,

with great pleasure we welcome you on behalf of the Austrian Society of Allergology and Immunology (ÖGAI) to the 4th European Congress of Immunology (ECI) in Vienna from September 6-9, 2015. After the scientifically and socially very successful congresses in Paris, Berlin and Glasgow, we are honored to host the 4th ECI, which is organized under the auspices of the European Federation of Immunological Societies (EFIS), in the heart of Europe. We have received more than 3.000 abstracts from Europe and Overseas and are especially proud and very thankful for the large international recognition of the 4th ECI, which goes far beyond the boundaries of Europe. In fact, more than 100 abstracts have been submitted by colleagues from both USA and Brazil, more than 70 abstracts have been submitted by colleagues from Australia and more than 60 abstracts have been submitted by colleagues from China. We take these record-high numbers as clear indication for the international attractiveness of European immunology research and realize that ECI congresses are receiving worldwide attention. The Scientific Program Committee has taken much effort to generate a timely and highly stimulating program consisting of four tracks covering the most recent developments in basic and clinical immunology. Exciting latest results and novel developments will be presented in 46 keynote lectures and symposia. At this point, we cordially thank all the members of the Scientific Program Committee, the Steering Committee and the Local Organizing Committee as well as the 93 reviewers for their invaluable contributions by critically evaluating all submitted abstracts. The committee members have selected 432 abstracts to be orally presented and the most excellent amongst them will be featured in specially dedicated ‘bright sparks’ workshops. In addition, more than 2.500 abstracts will be presented and discussed in 126 guided poster sessions during the fourday congress. We also express our deep gratitude to all related Societies dealing with immunology, clinical immunology, allergology and applied sciences, who have shown enormous enthusiasm in organizing additional joint symposia with EFIS, amongst them the European Academy of Allergy and Clinical Immunology (EAACI), the European Society for Immunodeficiencies (ESID), the European League Against Rheumatism (EULAR), the American Association of Immunologists (AAI), the International Union of Immunological Societies (IUIS), the World Allergy Organization (WAO), the International Society for Advancement of Cytometry (ISAC) and the Society for Mucosal Immunology (SMI). In addition to this fruitful cooperation the communication and collaboration with the related industry has been outstanding. As a result, more than 55 partners from industry will attend as exhibitors and a considerable number of company sponsored symposia and ‘progress in technology’ sessions will introduce you to the latest developments in flow cytometry, immune-adsorbers, vaccination against infectious diseases and tumors and allergy diagnosis amongst other topics. Moreover, the scientific program is framed by a considerable number of very interesting satellite symposia and meetings taking place either shortly before or directly after the main congress. On top of that, we invite you to the ‘EFIS Award Lectures’ on Monday 7th September presenting the recipients of the prestigious Ita Askonas Prize and the ACTERIA Doctoral and Early Career Research Prizes. The winners will give a short presentation about their awarded work. Finally, on Wednesday 9th September, the ‘First EFIS President’s Symposium’, convened and chaired by outgoing EFIS President Lorenzo Moretta, will explore ‘NK Cells and NK Cell-based Therapies of Leukemias’.

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Welcomes

WELCOME BY THE ECI ORGANIZERS

The support of the participation of early career scientists at events like the 4th ECI represents a cornerstone of EFIS’ mission. Accordingly, EFIS has awarded more than 240 travel bursaries to European early career scientists. Similarly, the American Association of Immunologists (AAI), the International Union of Immunological Societies (IUIS) and ÖGAI provided grants of their own (40, 10 and 10, respectively) to applicants from developing countries. Moreover, many national societies have allocated substantial support to stimulate and promote the participation of their younger members at ECI 2015. To further promote early career scientists special lectures will be provided, e.g. ‘How to publish in scientific journals’ and ‘Women in immunology’. In addition, early career scientists will have the opportunity to meet keynote lecture and symposia speakers in an interactive discussion atmosphere during breakfasts. Furthermore, guided poster sessions chaired by senior scientists and conducted at time-slots not interfering with workshops will encourage active discussion of scientific results to acknowledge the large contribution of early career scientists to this congress and to provide a stimulating feedback atmosphere for their scientific work. The best poster presenters within each session will compete for 12 poster prizes to be awarded during the closing ceremony. Outstanding immunological research has a long and strong tradition in Vienna. In fact, More than one hundred years ago, the Viennese Nobel laureate Karl Landsteiner discovered the blood groups and Clemens von Pirquet coined the term ‘Allergy’ in Vienna. Vienna’s contributions to the emerging field of immunology and allergology research at the turn of the last century will be high-lighted by a special historic exhibition, kindly curated by Johann Eibl and Othmar Förster, in the main lobby of the Austria Center Vienna. The exhibition will also be open to the lay public. We are indebted to the curators as well as the institutional and corporate sponsors of this interesting and eye-catching exhibition. After the opening keynote lecture given by the doyen of B cell biology, Klaus Rajewsky, on ‘The B cell receptor in B cell development, memory and malignancies’ we invite you to join us for the networking mixer in the Austria Center Vienna, which will take place immediately after the opening ceremony. Moreover, please consider to exchange thoughts and scientific opinions with your colleagues and friends on Tuesday, September 8, at the occasion of the Heurigen Networking Evening in Gumpoldskirchen. We express our deep gratitude to all those individuals and institutions, who made the 4th ECI possible. Many thanks to all committee members, who continuously contributed to the organization of this congress during the last years. A big thank you also to the generous support from our corporate partners, without their contributions it would have been impossible to put such a fantastic program together. Last but not least, we would like to thank the City of Vienna for kindly hosting us. Finally, we hope you will feel very comfortable in Vienna and we wish you a most memorable scientific, social and cultural stay!

Winfried F. Pickl, MD President 4th ECI

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Barbara Bohle, PhD President Scientific Program Committee 4th ECI

Rudolf Valenta, MD President Local Organizing Committee 4th ECI

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Welcomes

WELCOME BY THE EFIS PRESIDENT

Dear Friends and Delegates,

As President of the European Federation of Immunological Societies (EFIS), it is a distinct pleasure and honor for me to welcome you to the Fourth European Congress of Immunology – ECI 2015! The ECI, the venue of which is selected every three years (six years in advance) through a bidding process by the Federation’s 31 Member Societies, is the EFIS flagship event. At the 2nd ECI held in Berlin in 2009, EFIS Members overwhelmingly chose the bid submitted by the Austrian Society of Allergology and Immunology (ÖGAI) to host ECI 2015 in Vienna. And they did well to do so: I am convinced – after having worked closely with our colleagues of the ÖGAI over the past three years – that they are beyond worthy of the trust that EFIS Member Societies have placed in them! Our Austrian hosts – so admirably coordinated by Winfried Pickl, Barbara Bohle and Rudolf Valenta, respectively, Presidents of the ECI 2015 Steering Committee, Scientific Program Committee and Local Organizing Committee – have put together what is poised to be a truly meaningful event. A stellar lineup of speakers will explore over the next three days – in four Keynote addresses, more than 40 symposia and 72 workshops – the most recent advances in the fields of innate immunity, adaptive immunity, diseases of the immune system and immune interventions. And whether you have a broad-ranging interest in the multiple facets of modern immunological research, or your focus lies in a particular niche, you will surely come away from ECI 2015 satisfied by the fine balance between basic and applied/translational research contributions that the organizers have assembled. Also – in keeping with the mission of EFIS to foster young scientists – early career scientists will also take center stage in a number of specially convened sessions: “poster walks” will be conducted by leading scientists to encourage dynamic interaction with presenters, from among whom the 12 best will be selected; the “Bright Sparks Workshops” will feature the authors of the best submitted abstracts scored and selected by European experts; and the ACTERIA Doctoral and Early Career Research Prizes awarded by EFIS will be presented for the second time. In addition to these, EFIS will acknowledge the work of the third EFIS-EJI Ita Askonas Prize, awarded to a prominent European female research group leader. And beyond the wealth of science that will be explored in detail over the next three days in the halls of the Austria Center, we cannot forget the cultural and social delights that Vienna – the capital of Mitteleuropa, the City of Music, the Imperial City – has to offer. Overall, as an ECI 2015 delegate, rest assured that a scientifically, socially and culturally rewarding experience is waiting for you! In closing, I cannot help but highlight that 2015 marks the 40th anniversary of the founding of EFIS, which will be commemorated, among other occasions, with the inaugural “EFIS President’s Symposium”. On behalf of EFIS and the entirety of its membership, and together with our colleagues of the ÖGAI, I am delighted that you have chosen to take part in what is arguably “the” showcase for the European immunological community and that this year promises to be a truly memorable event. Lorenzo Moretta President, EFIS

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ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

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Welcomes

WELCOME IN AUSTRIA

Ladies and Gentlemen, Dear Participants, I would like to welcome you to Austria and the beautiful city of Vienna. Medicine has a very long tradition in Vienna. Today we have one of the world’s leading medical universities and many research institutions of international acclaim. It is a great honor that experts of immunology from all over the globe gather in Vienna for the 4th European Congress of Immunology to discuss the important issues of immunology. The huge range of symposia, workshops and poster sessions will give the experts the opportunity to discuss in-depth new forms of immune interventions, technological innovations and research results. I am convinced that the scientific progress will be for the benefit of thousands of patients who suffer from immune-mediated diseases and immunodeficiency. I wish all participants a successful conference with many fruitful discussions! Yours sincerely, Dr.in Sabine Oberhauser, MAS Minister of Health Federal Ministry of Health Austria

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Welcomes

WELCOME IN VIENNA

Dear participants of ECI 2015,

As host city of the 4th European Congress of Immunology, Vienna combines two key traditions: its traditional role as an international meeting place for outstanding scientists, and the excellent worldwide reputation of the Vienna School of Medicine. For our city, this reputation is both an honour and a mission for the future. The important fact that this year’s ECI is hosted by the Austrian Society of Allergology and Immunology serves as yet another proof of our traditionally close connection to science and research. The network of medical services available to all population groups is a good indicator for assessing a society. Vienna has an excellent international track record here, which is also due to research in immunology and allergology - two medical fields of increasing importance. The ECI is bound to provide new momentum in these fields as it provides for an exchange of experiences, expert debates, and initiatives to promote education and training. This is what matters after all. I would like to wish all participants an inspiring and interesting congress, and hope that you will also keep good memories of your stay in Vienna. Dr. Michael Häupl Mayor and Governor of Vienna

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ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

ORGANIZATION Addresses. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 About. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Committees. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9

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Organization

ADDRESSES

ECI 2015 Congress President ao. Univ. Prof. Dr. Winfried F. Pickl Institute of Immunology Medical University of Vienna Lazarettgasse 19, 1090 Vienna, Austria [p]: 0043 1 40160 33245 [m]: 0043 664 80016 65017 [e]: [email protected]

EFIS Office Thomas Wiley EFIS Coordinator Istituto Giannina Gaslini Via Gerolamo Gaslini 5, 16147 Genova, Italy [p]: 0039 010 563 6805 6554 [m]: 0039 347 197 7015 [e]: [email protected]

ECI 2015 Congress Organization and Abstract Management WMA Kongress GmbH Alser Straße 4, 1090 Vienna, Austria [p]: 0043 1 4051383 16 [e]: [email protected]

ÖGAI Office Institut für Immunologie Lazarettgasse 19, 1090 Vienna, Austria [p]: 0043 660 4977161 [e]: [email protected]

ECI 2015 Exhibition and Sponsorship Management MAW – Medizinische Ausstellungs- und Werbegesellschaft Engerthstrasse 128, 1200 Vienna, Austria City office: Freyung 6, 1010 Vienna, Austria [p]: 0043 1 53663 71 [e] [email protected]

Congress Venue Austria Center Vienna Bruno-Kreisky-Platz 1, 1220 Vienna, Austria [w]: www.acv.at

ABOUT European Federation of Immunological Societies [EFIS] The European Federation of Immunological Societies (EFIS) is a non-profit umbrella organization that represents 31 immunological societies from all across Europe, and even beyond the borders to Israel. Every active member of any of its member societies is automatically considered an EFIS member and can as such benefit from EFIS programs. Thus EFIS represents more than 14,000 individual immunologists. The main goals of EFIS are the support of immunological research and education as well as strengthening scientific interaction amongst its members. EFIS especially focuses on supporting early career scientists, e.g. through fellowships or travel grants.

European Congress of Immunology [ECI] The European Congress of Immunology - ECI - is the triennial joint meeting of all EFIS member societies. It is one of the most renowned international conferences in the field of basic and clinical immunology and attracts up to 5,000 delegates. The ECI is "the“place to build your professional network as it offers the highest standards in terms of both scientific and social programs. Each EFIS member society can submit a bid to host an ECI. The 4th European Congress of Immunology is held under the auspices of the Austrian Society for Allergology and Immunology (ÖGAI) and the European Federation of Immunological Societies (EFIS).

Austrian Society for Allergology and Immunology [ÖGAI] The ÖGAI was founded in 1971 and represents Austrian scientists and practitioners interested in the physiology and pathophysiology of the immune response as well as the phenotypic expression, diagnosis and therapy of all diseases involving the immune system. ÖGAI supports excellence in education and training in the fields of allergology and immunology and further provides and also encourages the spread of specific information on the vital importance of the immune system and its disorders, such as allergy, autoimmunity, immunodeficiencies, to the lay, legal and professional public.

Under the auspices of EFIS, European Federation of Immunological Societies www.efis.org and the Austrian Society for Allergology and Immunology, ÖGAI www.oegai.org

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ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

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Organization

COMMITTEES

STEERING COMMITTEE

FINANCE COMMITTEE

LOCAL ORGANIZING COMMITTEE

Winfried F. PICKL, President Lorenzo MORETTA, EFIS President Georg WICK, ÖGAI Barbara BOHLE, ÖGAI Fatima FERREIRA-BRIZA, ÖGAI Rudolf VALENTA, ÖGAI Peter OPENSHAW, BSI Andreas RADBRUCH, DGfI Reina MEBIUS, NVVI Anna FOGDELL-HAHN, SSI Luisa Maria VILLAR-GUMERANS, SEI Vincenzo BARNABA, SIICA Anne HOSMALIN, SFI Günnur DENIZ, TSI Hans ACHA-ORBEA, SGAI Henrique VEIGA-FERNANDES, SPI

Hannes STOCKINGER, President Carsten WATZL, DGfI Lindsay NICHOLSON, BSI René TOES, NVVI Hanna JARVA, SSI Clemens SCHEINECKER, ÖGAI Eduard PALOU, SEI Massimo LOCATI, SIICA Paul GUGLIELMI, SFI

Rudolf VALENTA, President Barbara BOHLE, ECI 2015 SPC President Kaan BOZTUG Meinrad BUSSLINGER Thomas DECKER Manfred DIERICH Adelheid ELBE-BÜRGER Martha EIBL Wilfried ELLMEIER Michelle EPSTEIN Elisabeth FÖRSTER-WALDL Alexander von GABAIN Beatrix GRUBECK-LOEBENSTEIN Franz-Xaver HEINZ Wolfgang HOLTER Sylvia KNAPP Hans LASSMANN Mathias MÜLLER Josef PENNINGER Alexander ROSENKRANZ Armin SAALMÜLLER Marcus SAEMANN Clemens SCHEINECKER Veronika SEXL Maria SIBILIA Josef SMOLEN Georg STINGL Hannes STOCKINGER Giulio SUPERTI-FURGA Peter VALENT Arne VON BONIN Thomas WECKERLE Ursula WIEDERMANN Christoph ZIELINSKI Gerhard ZLABINGER

EFIS BOARD Lorenzo MORETTA, President René A.W. VAN LIER, President elect Catherine SAUTÈS-FRIDMAN, Past President Anna ERDEI, Secretary General Hannes STOCKINGER, Treasurer

SCIENTIFIC PROGRAM COMMITTEE Barbara BOHLE, ECI 2015 SPC President Rudolf VALENTA, ECI 2015 LOC President Winfried F. PICKL, ECI 2015 President Leonie TAAMS, BSI Hans Martin JÄCK, DGfI Rene TOES, NVVI Marie WAHREN-HERLENIUS, SSI Ignacio MELERO, SEI Massimo LOCATI, SIICA Roland LIBLAU, SFI Sabina RABATIC, CIS Günnur DENIZ, TSI Christian MUENZ, SGAI Peter KOROSEC, ISS

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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2018

ECI Istanbul, Turkey

5 European Congress of th

Immunology

September 12 - 15, 2018

www.eci2018.org

Under the auspices of EFIS, European Federation of Immunological Societies www.efis.org and the Turkish Society of Immunology www.turkimmunoloji.org.tr

EFIS European Federation of Immunological Societies

CONGRESS INFORMATION Registration Information. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Awards and Travel Grants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 Floor Plans . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Opening Hours. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Congress Information A-Z. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 ECI Social Media Guide. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 Information for Early Career Scientists . . . . . . . . . . . . . . . . . . . 24 Information for Speakers and Poster Presenters. . . . . . . . . . . 25 CME Accreditation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26

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Congress Information

REGISTRATION INFORMATION

before June 30, 2015 (reduced rate)

from July 1 to August 23, 2015 (regular rate)

after August 23, 2015 and on site

Day tickets on site

EFIS Members1

EUR 420,-

EUR 480,-

EUR 540,-

EUR 270,-

Non-Members

EUR 570,-

EUR 630,-

EUR 690,-

EUR 360,-

Students2

EUR 210,-

EUR 240,-

EUR 270,-

EUR 150,-

Lunch bags standard3 (per day)

EUR 12,-

EUR 12,-

N/A

N/A

Lunch bags premium3 (per day)

EUR 19,50

EUR 19,50

N/A

N/A

Registration fees Payment received:

Networking Event – Heurigen Evening4

EUR 60,-

Abstract Book (printed)

EUR 12,-

1

List of eligible national EFIS member societies can be found online at www.ecivienna2015.org/index.php/registration

2

Applies to under- and postgraduate students. Please provide a copy of a Student’s ID or a written confirmation (in English) signed by the head of department during registration.

3

Lunch bags could only be ordered prior to the congress, no onsite orders for lunch bags are possible! For those not ordering lunch bags a couple of onsite options are, however, available.

4

Entirely at participants’ expense

What is covered by the registration fee?

Cancellations and refunds

• Admission to all scientific sessions • Admission to industry exhibition • Admission to networking mixer • Electronic abstract book on USB, printed final program and printed poster listing • Coffee/tea during breaks from Monday, September 7 to Wednesday, September 9

Notice of cancellation must be made in writing by email or fax to the congress office. Registration fees may be refunded as follows:

Payment of Registration fees may be made in cash (in Euro only) or by credit/debit card (ECI accepts Mastercard, VISA and Maestro).

The date of receipt of the email or fax ID will be the basis for considering refunds. Refunds will be made after the congress. Cancelled lunch bags and Heurigen Tickets can not be refunded.

Written cancellation received: - before June 30, 2015: 75% refund - between July 1 and August 23, 2015: 25% refund - after August 23, 2015: no refund

Please note The reduced registration fee is only applicable, if it has been credited to the congress account before the deadline. Registering before June 30 or respectively August 23, 2015 without performing the actual payment is not sufficient to benefit from the reduction.

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Abstract Book A printed abstract book can be purchased at the onsite registration desk for EUR 12,-.

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Congress Information

AWARDS AND TRAVEL GRANTS ACTERIA-PRIZES AWARDED BY EFIS On the recommendations of the ACTERIA Prizes Selection Jury and the Foundation ACTERIA, EFIS is delighted to announce the laureates of the 2015 ACTERIA Prizes awarded by EFIS: Doctoral Prize in Allergology: Sandra Pahr Medical University of Vienna Nominated by the Austrian Society for Allergology and Immunology (ÖGAI) Doctoral Prize in Immunology: Chris Schiering The Francis Crick Institute - Mill Hill Laboratory, London Nominated by the British Society for Immunology (BSI)

Early Career Research Prize in Allergology: Thomas Marichal University of Liege Nominated by the the Belgian Immunological Society (BIS) Early Career Research Prize in Immunology: Dietmar Zehn Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne Nominated by the Swiss Society for Allergology and Immunology (SGAI) The ACTERIA Prizes awarded by EFIS will be formally conferred at a specially organized Plenary Lecture Session of the 4th European Congress of Immunology on Monday, September 7 from 14:00 to 15:30 hrs, during which each of the four laureates will present her/his work. The ACTERIA Doctoral Thesis Prizes carry a cash award of EUR 15,000, while the ACTERIA Early Career Research Prizes amount to EUR 30,000 each. In addition, awardees automatically qualify for 3-year research grants of up to EUR 50,000 annually.

EFIS/EJI ITA ASKONAS AWARD Dr. Karin Tarte, Director of the Microenvironement and Cancer Unit of the University of Rennes Faculty of Medicine (U 917 INSERM), has been chosen as the 2015 Laureate of the Ita Askonas Prize, awarded by EFIS together with its Official Journal, European Journal of Immunology (EJI), in recognition of outstanding leadership by a female immunologist over the past three years. The prize was established by the European Federation of Immunological Societies (EFIS) and the European Journal of Immunology (EJI) in order to acknowledge female group leaders in immunology who have run an independent laboratory for a minimum of four and no more than eight years. The board of EFIS had decided to establish this award also in consideration of gender-specific differences of career opportunities, such as possible delays due to pregnancy and motherhood. This prize consists of a EUR 20,000 cash award plus travel support to attend the European Congress of Immunology (ECI). The laureate must be prepared to present her work at the ECI. The EFIS-EJI Ita Askonas Prize, named after the renowned scientist who over a career spanning 60 years so heavily influenced the field of immunology and who maintained that "good science gets recognition regardless of the sex of the scientist", was awarded for the first time at the ECI 2009 in Berlin. The winner was Prof. Fiona Powrie from Oxford, UK. The second prize, awarded during the ECI 2012 in Glasgow, went to Dr. Francesca Granucci of the University of Milano-Bicocca.

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

13

Congress Information

AWARDS AND TRAVEL GRANTS EFIS-IL MOST CITED PAPER AWARDS EFIS/IL Most Cited Original Paper Award Bermejo, P., Martín-Aragón, S., Benedí, J., Susín, C., Felici, E., Gil, P., Ribera, J.M., Villar, A.M. Differences of peripheral inflammatory markers between mild cognitive impairment and Alzheimer's disease Volume 117, Issue 2, 15 May 2008, Pages 198–202 Cited 72 times in its first 3 years after publication! EFIS/IL Most Cited Review Award K.S.Siveen, Girija Kuttan Role of macrophages in tumour progression Volume 123, Issue 2, 27 April 2009, Pages 97–102 Cited 131 times in its first 3 years after publication! Description: The awards were established by the European Federation of Immunological Societies (EFIS) with general support from Immunology Letters, in order to recognize the most often cited original paper and review, respectively, within the first 3 years after publication, published in Immunology Letters. They are awarded triennially in combination with the European Congress of Immunology (ECI), for the first time during ECI 2012 in Glasgow. This year we honor the Most Cited Original Article and Review which appeared in IL from January 1, 2008 to March 15, 2015. Each prize consists of a EUR 5,000 cash award plus invitation and support of the key author to attend the ECI.

TRAVEL GRANTS ECI-EFIS 2015 Travel Grants for Early Career Scientists from EFIS Affiliated National Immunological Societies The European Federation of Immunological Societies (EFIS), sponosred by the European Journal of Immunology and Immunology Letters, is awarding 245 travel grants at the value of EUR 600.- each for young post-docs and PhD-students under 35 years of age requesting financial support to attend the ECI 2015 and is pleased to announce the following EFIS travel grant awardees: Austrian Society for Allergology and Immunology (ÖGAI) Karine De Amicis Christoph Jandl Sahar Kazemi* Barbara Kronsteiner-Dobramysl Xin Li Shu-Hua Liu* Simone Mader Bharani Srinivasan* Philipp Starkl Marion Steger Helen Strandt * based in Vienna, Award value of EUR 200.-

Belgian Immunological Society (BIS) Ellen Brisse Pauline Lehebel Arnaud Machelart Valerie Martinet Barbara Polese Karen Put Catherine Sabatel British Society for Immunology (BSI) Giuseppina Arbore Dominic Boardman Marianne Burbage Joana Campos Lewis Clarke Ee Lyn Lim Anna Malecka Helen McGettrick Paul Milne Dhiren Patel Ann-Kathrin Reuschl

14

Joanne Simpson Nathalie Steinthal David Tomaz Bulgarian Society for Immunology (BuSI) Marina Alexandrova Ivaylo Balabanov Tsvetelina Batsalova Silviya Bradyanova Maya Hadzhieva Iva Ivanova Maria Kazakova-Velinova Iliyan Manoylov Croatian Immunological Society (HID) Marina Babic Cac Vedrana Jelenčić Tomislav Kelava Lovro Lamot Maja Lenartić Marko Šestan Czech Immunological Society (CIS) Viktor Bugajev Fabian Caja Viktor Černý Stepan Coufal Adela Dusilova Veronika Horková Michaela Hornová Jiri Hrdy Klara Klimesova Tomas Paulenda Lucie Potůčková Ladislav Sivak Ivan Stepanek Zuzana Zakostelska

Dutch Society for Immunology (NVVI) Anne Marit de Groot Ilse Dingjan Jennifer Hope Daniëlle Verboogen Marjolein Wentink French Society for Immunology (SFI) Alexandra Audemard-Verger Pascal Azar Sara Basbous Gaetan Blaize Lloyd Bod Laure Castan Clotilde Guyon Myriam Hayder Mathieu Ing Annaelle Jarossay Régis Joulia Clement Levin Yuting Ma Charlotte Pouchy Emilie Ronin Georgian Association of Allergology and Clinical Immunology (GAACI) Nino Nanava Yan Sepiashvili German Society for Immunology (DGfI) Fatima Ahmetlic Petra Bacher Jonas Blume Carola Bunse Lucia Campos Carrascosa Michael Delacher

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Congress Information

AWARDS AND TRAVEL GRANTS



Christiane Göpfert Lukas Heger Ann-Cathrin Hofer Isabel John Annett Kessler Elisabeth Littwitz-Salomon Anna Nowak Lucas Otto Friederike Raczkowski Annika Reinhardt Andreas Schlitzer Franziska Schmidt Kathrin Schulz Ping Shen Julia Spanier Yilang Tang Ulrike Träger Alexander Ulges Franziska Weber Anne Willing Kai Yu

Marija Stankovic Milica Vujičić Immunology Society of Slovenia (ISS) Mark Kačar Jelka Pohar Irish Society for Immunology (ISI) Laura Cahill Jennifer Corbett Maja Kristek Paul Lohan Kevin Lynch Izabela Marszalowska Ewa Oleszycka Grace O'Malley Mark Robinsdon Ralitsa Vassileva Mieszko Wilk

Hellenic Society of Immunology (HSI) Maria Semitekolou Panagiota Spantidea Eleftheria Anastasopoulou Antonios Gerofotis Ioannis Panagoulias Maria Rodi Ioanna Zerva Hungarian Society for Immunology (MIT) Zsuzsanna Bankó Beáta Szilvia Bolla Marietta Budai Judit Danis Anikó Göblös Adrienn Gyöngyösi Zoltán Kohl Mariann Kremlitzka Réka Kugyelka Adrienn Lajkó Nikolett Lupsa Anett Mázló Barbara Molnár-Érsek Kitti Linda Pázmándi Judit Pozsgay Lilla Prenek Noémi Sándor Florentina Sava Eszter Szarka Eszter Szlavicz Márta Tóth Dóra Vojkovics Immunological Society of Serbia (ISoS) Nemanja Jovicic Ilija Jeftic Jelena Demenesku Tanja Dzopalic Milan Marković Emina Milosevic Marina Ninkov Verica Paunovic Aleksandra Popov Aleksandrov Suzana Stanisavljević

Italian Society for Immunology, Clinical Immunology and Allergology (SIICA) Paolo Ambrosini Eduardo Bonavita Francesco Borriello Monica Castellucci Valerio Chiurchiù Sara Costa Daniele Croxatto Claudia De Pasquale Cinzia Garofalo Anna Kabanova Monica Loi Matteo Massara Michela Mirenda Martina Molgora Eleonora Palella Laura Pisapia Nicla Porciello Naths Grazia Sukubo Rossana Tallerico Eleonora Timperi Latvian Association of Immunologists (LAI) Aigars Dzalbs Lithuanian Society for Immunology (LSI) Dovile Dekaminaviciute Polish Society for Fundamental and Clinical Immunology (PTDiK) Dorota Iwaszkiewicz-Grzes Urszula Kozlowska Natalia Marek-Trzonkowska Katarzyna Nazimek Justyna Roszkowiak Urszula Skalska Tomasz Wypych Aneta Zegar Agata Zerka Portuguese Society for Immunology (SPI) Ana Margarida Ferreira Teixeira Liliana Oliveira Sérgio Ribeiro Ana Rita Santos

Russian Society for Immunology (RSI) Alina Alshevskaya Egor Batorov Elena Blinova Svetlana Falaleeva Nikita Mitkin Vadim Nazarov Mikhail Pogorelyy Lidia Putlyaeva Baigalmaa Sangidorj Ivan Zvyagin Scandinavian Society for Immunology (SSI) Magdalena Bosma Madelene Dahlgren Sophie Schussek Kailash Singh Slovak Immunological Society (SIS) Lucia Paulovičová Beata Gajdosechova Spanish Society for Immunology (SEI) Fernando Aranda Selene Baos Juan Antonio Calatayud Subias Aranzazu Cruz Adalia Marta Cuenca Vanessa Daza Cajigal Spanish Society for Immunology (SEI) (cont’d) Rebeca de Pablo Carlos Del Fresno Sánchez Sara Labiano Maria Martinez López Pascual Martínez-Peinado Anna Mensa-Vilaró Marta Mosquera Sáiz Miguel Muñoz Ruiz Carmen Picon Dalia Raich-Regue Swiss Society for Allergology and Immunology (SSGAI) Nicolo Brembilla Marco Fischer Samuel Philip Nobs Carsten Riether Turkish Society of Immunology (TSI) Soner Yildiz Lacin Cevhertas Ersin Gül Gurcan Gunaydin Bilgi Güngör Elif Senem Kayali Ece Canan Sayitoglu Burcu Sirin Gurcan Tunali Digdem Yoyen-Ermis Ukrainian Society of Specialists in Clinical Immunology and Allergy (UTIAI) Dmytro Butov

Grants will be paid by bank transfer after ECI 2015 has taken place. In order to claim their award, grant holders will be required to confirm their attendance during the congress to the EFIS booth in the ECI Immunology Village.

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

15

Congress Information

AWARDS AND TRAVEL GRANTS

ECI-AAI Travel Grants for Trainees from Developing Countries The European Congress of Immunology is pleased to announce the following travel grant awardees sponsored by the American Association of Immunology (AAI) with EUR 600.- as a contribution towards travel expenses: Lucas Arruda; Ribeirão Preto, Brazil Tarcio Braga; Sao Paulo, Brazil Abigael Buigut; Eldoret, Kenya Saswati Das; New Delhi, India Joao Paulo do Carmo; Porto Nacional, Brazil Yusuf Dolen; Ankara, Turkey Syed Faisal; Aligarh, India Wynand Goosen; Cape Town, South Africa Valeriia Guselnikova; St. Petersburg, Russian Federation Jaquelina Julia Guzmán Rodríguez; Morelia, Mexico Zeb Hussain; Karachi, Pakistan Sevgi Irtegun; Diyarbakır, Turkey

Léanie Kleynhans; Cape Town, South Africa Manoj Kumar; New Delhi, India Sushil Kumar; Bhopal, India Neha Lohia; Patiala, Punjab, India Andres Machicote; Buenos Aires, Argentina José Maravillas-Montero; México, Mexico Jelena Milovanovic; Kragujevac, Serbia Ricardo Mora; San José, Costa Rica Roman Moriev; Kyiv, Ukraine Shibabrata Mukherjee; Kolkata, India Anastasia Myrzakova; Moscow, Russian Federation Neema Negi; New Dlehi, India Tetiana Nikolaienko; Kyiv, Ukraine Viktoriia Nikulina; Kyiv, Ukraine

Tashnica Olivier; Cape Town, South Africa Gustavo Olvera-García; Tlalpan, Mexico Raphael Peres; Sao Paulo, Brazil Ariel Podhorzer; Buenos Aires, Argentina Susmita Roy; Kolkata, India Iti Saraav; Delhi, India Cristiane Secca da Silva; Rio de Janeiro, Brazil Ahmed Seida; Giza, Cairo, Egypt Mahima Sharma; New Delhi, India Om Singh; Varanasi, India Sukrat Sinha; Allahabad, India Shivendra Tenguria; Hyderabad, India Vipin Tyagi; Delhi, India Galyna Yeryomenko; Kharkov, Ukraine

Grants will be paid in cash onsite during registration.

IUIS Travel Grants for Early Career Scientists from IUIS Affiliated National Immunological Societies The European Congress of Immunology is pleased to announce the following travel grant awardees sponsored by the International Union of Immunological Societies (IUIS) with EUR 600.- as a contribution towards travel expenses: Chidimma Atukpawu; Imo State, Nigeria

Donald Nyangahu; Cape Town, South Africa

Yung-Sen Chang; Taipei, Taiwan

Zahra Salahi; Tehran, Iran

Jeewon Lee; Daejeon, Korea, Republic of

Alberto Salazar; Mexico City , Mexico

Pu Li; Shanghai, China

Jimena Tosello-Boari; Córdoba, Egypt

Sakshi Malik; Faridabad, India

Nuria Zurro; São Paulo, Brazil

Grants will be paid in cash onsite during registration.

ÖGAI Travel Grants for Early Career Scientist from Developing Countries The European Congress of Immunology is pleased to announce the following travel grant awardees sponsored by the Austrian Society for Allergology and Immunology (ÖGAI) with EUR 600.- as a contribution towards travel expenses: Olena Dzhus; Kyiv, Ukraine

Gaurab Sircar; Kolkata, India

Nevin Hammam; Assiut, Egypt

Roman Sydor; Kyiv, Ukraine

David Mzinza; Hannover, Germany

Maia Tsitsuashvili; Moscow, Russian Federation

Paul Ogongo; Nairobi, Kenya

Luan Vu; Sydney, Australia

Pramila Rijal; Oxford, United Kingdom

Michael Zulu ; Durban, South Africa

Grants will be paid in cash onsite during registration.

16

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Congress Information

AWARDS AND TRAVEL GRANTS EFIS-BIOLEGEND BRIGHT SPARKS AWARDS With the generous support of Biolegend, EFIS is able to sponsor 24 Bright Sparks Awards during the ECI 2015. The Scientific Committee selected the 24 best abstracts submitted by early career scientists. Those abstracts are presented in the "Bright Sparks" Workshops, taking place throughout the day on Monday (Hall F1). In addition to recognition as an ECI 2015 "Bright Spark", all speakers will also receive a EUR 500,- cash prize. Prizes will be awarded during the Closing and Award Ceremony on Wednesday, September 9, 17:45 – 18:45 hrs (Hall A).

EFIS POSTER PRESENTATION AWARDS The EFIS proposes 12 Poster Presentation Awards for the best posters presented during the ECI 2015 in Vienna. The winners will receive a EUR 300,- cash prize. Poster Chairpersons will evaluate all posters presented during the guided poster sessions. Award Candidate Posters will be moved to a designated area (on the left when entering the exhibition / poster area) by the congress staff and will be displayed during all congress days. Final decisions on winners will be made by an award jury on Wednesday. Prizes will be awarded during the Closing and Award Ceremony on Wednesday, September 9, 17:45 – 18:45 hrs (Hall A).

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

17

Congress Information

Poster

Exhibition (X2)

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Society Village Poster Award Candidates

Poster

Poster

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€

Level 18

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Congress Information

FLOOR PLANS LEVEL 2

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www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

19

Congress Information

OPENING HOURS

Opening hours

Congress Information Desk

Registration Desk

Speakers‘ Preview

Accommodation & City Desk

Poster Printing Desk

Cloakroom

Sunday, Sept 6

10:00 – 20:00 10:00 – 20:00 10:00 – 20:00

10:00 – 20:00

10:00 – 20:00 10:00 – 22:30

Monday, Sept 7

07:30 – 19:30 07:00 – 19:30 07:30 – 19:30

07:30 – 19:30

07:30 – 18:00 07:30 – 21:00

Tuesday, Sept 8

07:30 – 19:30 07:00 – 19:30 07:30 – 19:30

07:30 – 19:30

07:30 – 18:00 07:30 – 19:30

Wednesday, Sept 9

07:30 – 16:30 07:00 – 16:30 07:30 – 16:30

closed

07:30 – 11:30 07:30 – 19:30

Opening hours

Exhibition Service Desk

Exhibition

poster mounting

poster removal

Saturday, Sept 5

08:00 – 20:00

build up

no

no

Sunday, Sept 6

08:00 – 20:00

build up

no

no

Monday, Sept 7

08:00 – 18:30 09:00 – 18:00 07:30 – 08:30 18:00 – 19:30

Tuesday, Sept 8

08:00 – 18:30 09:00 – 18:00 07:30 – 08:30 18:00 – 19:30

Wednesday, Sept 9

08:00 – 22:00 09:00 – 16:30 07:30 – 08:30 16:00 – 17:45

CONGRESS INFORMATION A-Z App information

Badges

The ECI smartphone app can help you to get the best out of the ECI!

Each participant receives a name badge upon check-in at Registration. As only registered participants will be permitted to attend the scientific sessions, the exhibition and poster areas, you are required to wear your badge when entering and while remaining in the congress venue. If you have lost your badge, a new one can be purchased (with proof of your original registration) at the Onsite Registration Desk for EUR 60,-.

The app allows you to: - browse, search and personalize the entire event program - access useful information about the congress - access all abstracts - create and synchronize events with your personal calendar The app allows users to access information offline to avoid roaming costs. It can be downloaded from your app store and works with iOS and Android. Search your app store for ECI 2015. ECI thanks Abbvie for their generous sponsorship of the Congress App.

20

IMPORTANT: Please have your badge scanned daily at the Congress Information Desk in order to claim the full amount of CME credits.

Bank Services - Money Matters Banks are generally open Monday to Friday from 09:00 – 15:00. Some banks are also open until 18:00 on weekdays. Cash machines (ATMs), which accept all major international bank cards, are available throughout the city. The currency of Austria is the Euro (€). Major credit cards are widely accepted, but please always check beforehand. The nearest bank is located on the way from the subway station to the congress venue.

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Congress Information

CONGRESS INFORMATION A-Z

Business Centre

Drinking Water

The closest Business Centre is Repa Copy located on the way from the subwaystation to the congress venue (Donaucitystraße 4). Opening hours : Monday to Friday – 08:00 – 20:00, Saturday and Sunday - closed.

The tap water in Vienna is drinkable and is of very high quality (mountain spring water).

Certificate of Attendance

ECI 2015 delegates are cordially invited to visit the EFIS Booth c/o the Immunology Village for a coffee and to take part in the traditional “EFIS Passport to Prizes” raffle for a chance to win numerous prizes, including travel grants to future immunology events and subscriptions and textbooks from EFIS’ Official Journals.

Certificates of attendance will be issued at the registration desk. CME accreditation certificates can be downloaded from the congress website (www.eci-vienna2015.org) from Friday, September 11, 2015. More details will be sent to you via email after the congress. For more details, please ask at the Congress Information Desk in the main Entrance Hall.

EFIS Booth

Emergencies

Climate The average temperatures in September in Vienna are 20°C (high) and 12°C (low). The average number of rainy days is 7 with an average rainfall of 45 mm.

Please contact a member of congress staff immediately in the case of a real or suspected emergency situation. The European emergency number applies in Austria, and callers should dial: 112.

Coffee Breaks During the session breaks, refreshments (coffee, tea and water) will be served free of charge to participants wearing name badges. On Monday, Tuesday and Wednesday coffee and lunch bags (pre-ordered ) will be served in the exhibition area (Hall X1+X2).

Cloakroom A cloakroom (with luggage storage) is located in the entrance hall. Charge: EUR 2.- per item Free of charge on Wednesday, September 9 Opening Hours: Sunday, September 6 Monday, September 7 Tuesday, September 8 Wednesday, September 9

10:00 – 22:30 07:30 – 21:00 07:30 – 19:30 07:30 – 19:30

Exhibition The ECI 2015 industry exhibition will be open during the following times: Monday, September 7 Tuesday, September 8 Wednesday, September 9

09:00 – 18:00 09:00 – 18:00 09:00 – 16:30

The Publishers’ Corner and the Society Village are located in the Exhibition Hall.

Flight Check-in Flight check-in terminals will be available to delegates in the registration area for online flight check-in. A printer will be available to print boarding passes. This service will be open from Tuesday, September 8 15:00 to Wednesday, September 9 16:30.

Continuing Medical Education (CME) Credits ECI 2015 has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME), an institution of the European Union of Medical Specialists (UEMS) in cooperation with the European Board of Accreditation in Allergy and Clinical Immunology (EBAACI) to provide the following CME activity for medical specialists. The Congress is designated for up to 18 hours of European external CME credits (ECMECs). Please see page 26 for more information on how to claim your CME credits.

Currency Austria is a member of the Economic and Currency Union and the common currency is the Euro. The official currency in the Austria is the EURO (EUR). 1 EUR = 1,10 USD = 0,70 GBP = 1,42 CAD = 136,20 JPY = 1,06 CHF = 1,50 AUD as per August 1, 2015.

www.eci-vienna2015.org

Food and Beverages The main catering services (coffee and lunch bag stations) as well as a snack bar and a smoothie bar are located in the Exhibition Hall. In the entrance area you will find the Motto Café offering cold and warm snacks as well as a curry bar offering different curries each day. A traditional “Wiener Würstelstand” offering different kinds of sausages is located outside the main entrance. Coffee and tea during official coffee breaks is included in the registration fee. Lunch bags are not included in the registration fee and had to be pre-ordered. For logistical reasons lunch bags cannot be ordered onsite. Lunch bags can be picked up from 12:15 – 14:15 on Monday, Tuesday and Wednesday.

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

21

Congress Information

CONGRESS INFORMATION A-Z

Opening Hours Food Outlets

Online Program Planner

Snack Bar and Smoothie Bar Exhibition Area Monday, September 7 09:00 – 18:00 Tuesday, September 8 09:00 – 18:00 Wednesday, September 9 09:00 – 16:30 Motto Café Registration Area Saturday, September 5 Sunday, September 6 Monday, September 7 Tuesday, September 8 Wednesday, September 9

08:00 – 17:00 08:00 – 17:00 08:00 – 19:00 08:00 – 19:00 08:00 – 17:00

Entrance Level Curry Bar Sunday, September 6 Monday, September 7 Tuesday, September 8 Wednesday, September 9

11.30 – 15.00 11.30 – 15.00 11.30 – 15.00 11.30 – 15.00

Outside Coffee Bar / Würstelstand Sunday, September 6 Monday, September 7 Tuesday, September 8 Wednesday, September 9

10.00 – 15.00 08.00 – 15.00 08.00 – 15.00 08.00 – 15.00

Internet Access For WiFi access, choose the ECI 2015 network. The password is eci2015.

Job Announcements Job announcements can be displayed on a designated info wall in the exhibition area.

Language The official language of the congress is English. No simultaneous translation is provided.

Lost and Found Please contact the Congress Information Desk in the registration area for personal belongings that have been lost or found.

Message Board Message boards will be available in the exhibition area.

An online program planner to create your individual itinerary including the full information on all sessions, speakers, chairs and abstracts is available online on the Congress website: www.eci-vienna2015.org. The online planner has a search function with which you can find speakers, topics, session types and much more. You can also build your personal Congress itinerary by selecting presentations and sessions from the program, using the search tool. The itinerary can be printed, exported as csv/excel file. It can also be exported to your calendar in various systems (such as MS Outlook and Apple iCalendar). It is also possible to find single abstracts. Alternatively, why not download the Congress app for full information on the Scientific Program and more.

Parking The Austria Center Vienna provides covered, secure parking for delegates. - Disabled parking spaces in the multi-storey garage - Parking for about 40 coaches at main entrance level - Ample HGV parking at „Ladehof West“ Parking fees up to 30 minutes 1 hour: Each additional hour: Max. daily fee:

free EUR 3,EUR 1,EUR 10,-

Pharmacies Most pharmacies are generally open weekdays from 8.0012.00 and 14:00 – 18:00 hrs, Saturdays from 8.00-12.00, some until 18.00 hrs and closed on Sundays. After 18:00 you find a list of “emergency” pharmacies (open during the night and on weekends) in the surrounding.

Poster Exhibition Scientific posters are displayed in the poster area in the Exhibition Hall. Posters will be displayed for a full day either on Monday, Tuesday or Wednesday. Each day, the posters are organized in thematic groups of approx. 20 posters. During the poster sessions the presenters are required to stand by their posters to deliver a concise poster presentation of not more than 3 minutes and to answer questions from delegates. During this time, two chairpersons per group will also visit each poster and ask the presenters to briefly present their findings. Visit the Poster Information Desk for any questions you might have regarding the poster presentations.

Mobile Phone Policy Please respect the congress policy and keep mobile phones on silent in all meeting rooms, the Exhibition Hall and Poster Area.

22

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Congress Information

CONGRESS INFORMATION A-Z

Poster Removal

Insurance/Liabilities and Disclaimer

The organisers cannot assume any liability for loss or damage of posters displayed in the poster area. Posters need to be removed on the day of presentation between 18:00 – 19:30 hrs strict (16:00 – 17:45 hrs on Wednesday).

ECI will not be held liable for personal injuries or for loss of or damage to property incurred by participants at the ECI 2015. Participants are encouraged to purchase insurance to cover loss incurred in the event of cancellation, medical expenses, or damage to or loss of personal effects when travelling outside of their own countries. ECI cannot be held liable for any hindrance or disruption of the ECI Congress 2015 proceedings arising from natural, political, social or economic events or other unforeseen incidents beyond its control. Registration of a participant implies acceptance of this condition.

Access after 19:30 hrs (17:45 hrs on Wednesday) is not possible! Posters not removed until 19:30 hrs on the day of presentation (17:45 hrs on Wednesday), will be taken down by the staff of the conference center and will not be stored or sent to the authors after the meeting.

Photographing and Recording Taking photographs or making any other form of electronic recording (also with mobile phones) during the sessions in the meeting rooms is forbidden.

Safety and Welfare Vienna can be considered just as safe as other comparable cities in Europe. Use of common sense is however (always) required. Unfortunately, experience has shown that some basic precautionary measures should always be kept in mind in any city: - Do not carry important items like flight tickets, passports etc. with you when visiting the congress or strolling through the city, leave them in the hotel safe during your stay. Rather carry a Xerox copy of your passport or an identity card with you. - Try not to carry all documents, money, credit cards and other essential items and valuables in one bag. If it is lost or stolen, everything will be gone and might be difficult to replace on short notice, especially passports and visa to return to your country of residence. - Take off your name badge when leaving the congress venue. - In heavily frequented tourist zones, be aware of attemps of scam and pickpocketing. ECI / EFIS holds a very firm position against any form of discrimination or untoward behaviour by Congress participants. If any participant feels that they have been subjected to any inappropriate behaviour, please report it immediately to a senior member of Congress staff at the General Information Desk in the Registration Area and the matter will be referred to the local authorities for further investigation.

www.eci-vienna2015.org

Session Attendance Sessions may fill up quickly. Please arrive in good time for the start of the session. Due to security regulations, hosts and hostesses are instructed to restrict access once the maximum capacity of the room is reached.

Society Village The society village is located in the exhibition hall. National EFIS affiliated societies as well as international associations will provide a platform for international exchange and inform about the newest developments in their own countries.

Speaker Preview The Speaker Preview is located on level 0 in room 0.93. The opening hours are: Sunday, Sept 6 Monday, Sept 7 Tuesday, Sept 8 Wednesday, Sept 9

10:00 – 20:00 07:30 – 19:30 07:30 – 19:30 07:30 – 16:30

Staff If you should have any questions, the congress staff (recognizable by a badge and a blue t-shirt) will be pleased to help you.

Telephone Calls The country code of Austria is 43 and the area code for Vienna is 1, followed by a 7 digit number. To call abroad, dial 00 before the country code.

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Congress Information

ECI SOCIAL MEDIA GUIDE

Get the latest news! Follow us on twitter @2015ECI. For a live feed from the congress, follow @2015ECI on Twitter. We will give you full congress coverage, daily photos, news and much more. Share your thoughts – use the official hashtag But that’s only the half of it. We want your comments, ideas, thoughts, and congress experiences. Post them on your twitter, mention @2015ECI or use the official hashtag #ECI2015 in your tweets. Spread the word! Your friends back home can join us online. Your colleagues can also join you at the ECI 2015, online and live via our twitter stream. Just invite everyone to follow us @2015ECI

INFORMATION FOR EARLY CAREER SCIENTISTS HOW TO GET THE MOST OUT OF YOUR FIRST ECI CONGRESS 1. Make a plan

5. Ask Questions

Spend some time thinking about the most important sessions and talks that you would like to see. The meeting program is also available online.

Don’t be shy about asking questions at the microphone! Everyone in the audience is there to learn – and so if you have a question, there’s every chance that others will have the same question.

Familiarize yourself with the color coded session types: different types are designed for a different audience. Avoid being disappointed by a session that will be too basic or too specialized for your interests, despite an interesting title.

2. Pace Yourself The meeting has a packed schedule. You will probably find something interesting and useful from 8:30 until 19.30 hrs each day – but we would not necessarily recommend to do so! You will get saturated pretty quickly, and by Monday or Tuesday your ability to absorb useful information will be severely diminished. Again, prioritize what is the most important.

6. Get There Early! This is a principle that will serve you well on many fronts. We have literally thousands of people attending the meeting, and yet some people are surprised to find lines at the registration desk on Sunday afternoon. You will not want to miss the opening ceremony – so get there early (registration opens at 10:00 on Sunday morning) – and is open all day Sunday to Wednesday. It is similar for the queues for food at the Networking Mixer reception (Monday evening). Just think, with 3000+ people, it is IMPOSSIBLE for everyone to get served immediately.

3. Parallel Events When you attend a session you might find that not all of the session is relevant or interesting to you, or you might have spotted a talk in another parallel session room that you’d like to see. It is completely okay to leave one session and join another (but etiquette dictates that you wait for the end of a talk to leave / join the audience).

4. Interact Make the most of the opportunity to network. Most people (junior or senior) are delighted to meet new faces and to chat about their work – so don’t be afraid to approach those big names and introduce yourself, and just start chatting!

24

7. Stay cool and relax! Sounds cheesy…. But the meeting is extremely busy, and you could try and push yourself to run between every single talk that you want to see, to try and see all 2500+ posters, to go to every symposium, workshop and so on….. but you’ll be exhausted! It is far better to have come away with some new friends, have chatted with a ‘big name’ in your field, and have two or three ‘nuggets’ of information that will shape your research.

8. Business Cards Although these are becoming a dying breed, we noted that having business cards ready to exchange was helpful, especially when another meeting attendee passes you theirs, but it is a matter of personal preference.

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Congress Information

INFORMATION FOR SPEAKERS AND POSTER PRESENTERS ORAL PRESENTATIONS Speaking Time The chairpersons of your session will be strict in allowing no more than the time allotted to present your work. Remember to allow some time for chairperson's introduction, questions and discussion of your presentation as well as the changeover of speakers.

Commercial Disclosure information Due to EACCME regulations, authors are requested to disclose possible conflicts of interest on the first slide. A conflict of interest is any situation in which a speaker or immediate family members have interests, and those may cause a conflict with the current presentation. Conflicts of interest do not preclude the delivery of the talk, but should be explicitly declared. These may include financial interests (eg. owning stocks of a related company, having received honoraria, consultancy fees), research interests (research support by grants or otherwise), organizational interests and gifts. If you have nothing to disclose, please state “I have no commercial disclosure”.

Projection and Technical Setting PowerPoint is the only communication tool available in all session halls. Overhead projection, slide projection or flipcharts are not available. 1. Speakers are kindly asked to observe that, in principle, only computers provided by the congress may be used for showing presentations. All PowerPoint presentations must be handed in at the speaker preview. Please contact the technicians in the speaker preview at least 2 hours prior to your session if you absolutely have to use your own computer. 2. All presentations are loaded into a PowerPoint handling system that will store and distribute your presentation to the session hall in time for your session. 3. All PowerPoint presentations should be handed in at least 2 hours before the session starts. 4. Please check your presentation carefully on the preview room computer assigned by the staff before the final sign off. 5. The professional staff of the speaker preview will load your presentation into the system so that it will be available on the computer in your session hall when you come to speak. 6. If you are doing more than one speech during the congress, you may upload all your presentations at the same time and they will be sent to their corresponding session halls at the time of your sessions. 7. The PowerPoint handling and distribution system is optimized for MS PowerPoint 2007 (Office 2007) and “*.pdf” (Adobe Acrobat)-files. The uploading of “DVD-Movies” is not supported. 8. The supported data media are: CD, DVD (as Data-storage-medium) and USB-Memory Key. All needed files (including the movie files!) - have to be saved on the data media. Presentations can also be taken off speakers notebooks at the Preview centre. 9. The fonts that are used in the presentations should be “Latin-based fonts“. If the speaker needs special fonts, they should be stored as “embedded fonts“ with the presentation (File -> save as “name of presentation“ and under “tools“ ->save options mark the checkbox “embed True type fonts“ and select “embed all characters“). 10. When using mathematical symbols please use these which are available under Latin fonts (unicode or DOS: Western Europe). These can be shown without any problems in Office 2007. 11. As format for embedded movies “MPEG2 - movies” are preferred (but can also be *.avi, *.wmv ). If Codecs are used, the Code package DIVx in the current version should be chosen. 12. Presentations should be saved as “*.ppt“, “*.pptx” (= PowerPoint) or “*.pps“,*.ppsx“ (=PowerPoint Slideshow) file and movies as separate files on the data media. 13. The computers and projectors will be set up and optimised for 1024 x 768 resolution (ratio 4 : 3).

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Congress Information

INFORMATION FOR SPEAKERS AND POSTER PRESENTERS POSTER PRESENTATIONS Schedule for display, mounting and removal Posters will be changed every day. Your poster will be on display during one of the following days: • Monday, September 7 (08:30 – 18:00 hrs) • Tuesday, September 8 (08:30 – 18:00 hrs) • Wednesday, September 9 (08:30 – 16:00 hrs) Poster mounting on the respective days will be possible between 07:30 – 08:30 hrs strict. Posters need to be removed on the day of presentation until 19:30 hrs strict (17:45 hrs on Wednesday). Access after 19:30 hrs (17:45 hrs on Wednesday) is not possible! Posters not removed until 19:30 hrs on the day of presentation (17:45 hrs on Wednesday), will be taken down by the staff of the congress venue and will not be stored or sent to the authors after the meeting. Contact the Poster Information Desk in the exhibition area if you need any assistance with your poster.

Important Guidelines • Due to EACCME regulations, authors are requested to disclose possible conflicts of interest on the poster. • When presenting data and health information (including photos) all presenters must have informed consent compliant with human subjects and applicable regulations.

Poster Printing Service The Poster Printing Service desk is located in the registration are. Onsite orders are possible. All detailed information on the Poster Presentations can be found in the separate poster information booklet.

CME ACCREDITATION The 4th European Congress of Immunology (ECI 2015) is accredited by the European Accreditation Council for Continuing Medical Education (EACCME) to provide the following CME activity for medical specialists. The EACCME is an institution of the European Union of Medical Specialists (UEMS). The 4th European Congress of Immunology (ECI 2015) is designated for a maximum of 18 hours of European external CME credits. Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity. The EACCME credit system is based on 1 ECMEC per hour with a maximum of 3 ECMECs for half a day and 6 ECMECs for a full-day event. Through an agreement between the European Union of Medical Specialists and the American Medical Association, physicians may convert EACCME credits to an equivalent number of AMA PRA Category 1 Credits™. Live educational activities, occurring outside of Canada, recognized by the UEMS-EACCME for ECMEC credits are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of The Royal College of Physicians and Surgeons of Canada.

CME ACQUISITION PROCEDURE The ECI 2015 is happy to introduce a digital CME acquisition system. Evaluation and CME acquisition will be possible online after the congress. An according email will be sent to all participants. Each ECI delegate will be able to view and print a confirmation stating the according number of CME credits. It is possible to claim a maximum of 18 CME points for attendance of scientific sessions at the ECI 2015. IMPORTANT: Please make sure to have your badge scanned daily at the Congress Information Desk in order to gain the maximum amount of CME credits. The printout of your record should be submitted to your national jurisdiction (usually responsible for accreditation) for approval of your CME points. Please note that the record of attendance will be issued only to the participant. It will not be supplied to any accreditation agency or other organisation. Please note that the ECI 2015 does not provide printed CME certifications onsite.

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ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

SCIENTIFIC PROGRAM Program at a Glance. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 How to Read the Scientific Program . . . . . . . . . . . . . . . . . . . . 36 Related Pre-Congressional Events in Vienna before the start of the 4th ECI Congress. . . . . . . . . . . . . . . . . . 40 Sunday. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 Monday . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 Tuesday . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61 Wednesday. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Scientific Program

PROGRAM AT A GLANCE

Sunday, Sept. 6, 2015 Room

Hall A

L2

L1

L8

Meeting Room 1 (1.85-86)

Meeting Room 2 (1.61)

Level

2

1

1

1

1

1

07:30 – 07:45 07:45 – 08:00 08:00 – 08:15 08:15 – 08:30 08:30 – 08:45 08:45 – 09:00 09:00 – 09:15 09:15 – 09:30 09:30 – 09:45

BA.02

09:45 – 10:00

IUIS Executive Committee Meeting

10:00 – 10:15 10:15 – 10:30 10:30 – 10:45 10:45 – 11:00 11:00 – 11:15 11:15 – 11:30 11:30 – 11:45 11:45 – 12:00 12:00 – 12:15

Scientific Satellite Meeting

Educational Course

Immunosenescence: Hot Topics and Interventions - Day 2

Advanced Cytometry Course

12:15 – 12:30 12:30 – 12:45 12:45 – 13:00 13:00 – 13:15

BA.04

ABIRISK Steering Committee (SC) Meeting

13:15 – 13:30 13:30 – 13:45 13:45 – 14:00 14:00 – 14:15

BA.05

14:15 – 14:30

German Society for Immunology (DGfI) Board Meeting

14:30 – 14:45 14:45 – 15:00 15:00 – 15:15 15:15 – 15:30 15:30 – 15:45

Scientific Satellite Meeting ABIRISK - Immune Reactions Against Biopharmaceuticals

15:45 – 16:00 16:00 – 16:15 16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 17:00 – 17:15 17:15 – 17:30 17:30 – 17:45

Opening Ceremony

17:45 – 18:00 18:00 – 18:15

KL.A.1

18:15 – 18:30 Adaptive Immunity The B Cell Receptor in B

18:30 – 18:45 Cell Development, Memory 18:45 – 19:00 and Malignancies 19:00 – 19:15

Opening of Historic Exhibition “Emerging Immunology – Vienna’s Contribution”

19:15 – 19:30 19:30 – 19:45 19:45 – 20:00 20:00 – 20:15 20:15 – 20:30

Networking Mixer

20:30 – 20:45 20:45 – 21:00 21:00 – 22:00

28

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Scientific Program

PROGRAM AT A GLANCE

Sunday, Sept. 6, 2015 Meeting Room 5 (2.17)

Meeting Room 8 (1.62)

2

1

Room Level 07:30 – 07:45 07:45 – 08:00 08:00 – 08:15 08:15 – 08:30 08:30 – 08:45 08:45 – 09:00 09:00 – 09:15 09:15 – 09:30 09:30 – 09:45 09:45 – 10:00 10:00 – 10:15 10:15 – 10:30

BA.03

10:30 – 10:45

SysmedIBD Consortium Meeting

10:45 – 11:00 11:00 – 11:15 11:15 – 11:30 11:30 – 11:45 11:45 – 12:00 12:00 – 12:15 12:15 – 12:30 12:30 – 12:45 12:45 – 13:00 13:00 – 13:15 13:15 – 13:30 13:30 – 13:45 13:45 – 14:00 14:00 – 14:15

Scientific Satellite Meeting Get to know SysmedIBD (EU-FP7 Project Systems Medicine of Chronic Inflammatory Bowel Disease)

BA.06

14:15 – 14:30

British Society for Immunology (BSI) Programme Committee Meeting

14:30 – 14:45 14:45 – 15:00 15:00 – 15:15 15:15 – 15:30 15:30 – 15:45 15:45 – 16:00 16:00 – 16:15 16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 17:00 – 17:15 17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 18:00 – 18:15 18:15 – 18:30 18:30 – 18:45 18:45 – 19:00

Opening of Historic Exhibition

19:00 – 19:15 19:15 – 19:30 19:30 – 19:45 19:45 – 20:00

Networking Mixer

20:00 – 20:15 20:15 – 20:30 20:30 – 20:45 20:45 – 21:00 21:00 – 22:00

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Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Scientific Program

PROGRAM AT A GLANCE

Monday, Sept. 7, 2015 Room

Hall A

Hall E

Hall F1

Hall F2

Hall G

Hall K

Level

2

0

0

0

-2

-2

07:15 – 08:15 08:15 – 08:30 08:30 – 08:45 08:45 – 09:00

S.A.01

Adaptive Immunity Protection by CD8 09:15 – 09:30 T Cells 09:00 – 09:15

S.B.01

Diseases Chronic Inflammation

BS.C.1

Bright Sparks Breakthroughs in Innate Immunity

WS.D.01

Immunosuppresive Therapies and Immunomodulation

WS.C.01

WS.C.02 Leukocyte Trafficking Innate Sensors

09:30 – 09:45 09:45 – 10:00 10:00 – 10:15 10:15 – 10:30

Poster Session and Guided Poster Walks / Coffee Break

10:30 – 10:45 10:45 – 11:00 11:00 – 11:15 11:15 – 11:30 11:30 – 11:45

S.C.01

11:45 – 12:00 Innate Immunity

12:00 – 12:15 Mucosal Immunity

S.D.01

Disease Intervention Vaccines

12:15 – 12:30

BS.B.1

Bright Sparks Insights in Immunological Disease Mechanisms

WS.A.01

Molecular & Cellular Control of CD8+ T Cells (part 1)

WS.B.02

WS.B.01

Generation of Allergen Specific Immune Responses

Control of Inflammation in Autoimmune Diseases

12:30 – 12:45 12:45 – 13:00

KL.C.1

13:00 – 13:15 Innate Immunity

Intestinal

13:15 – 13:30 Homeostasis and its 13:30 – 13:45 Breakdown 13:45 – 14:00 14:00 – 14:15

JS.01

14:15 – 14:30 American

Association of Immunologists (AAI) 14:45 – 15:00 Molecular Mechanisms of the 15:00 – 15:15 Immune Response to 15:15 – 15:30 Infection 14:30 – 14:45

JS.02

European League Against Rheumatism (EULAR) Resolution of Inflammation

EF.01

EFIS Awards Lecture Symposium (Industry Sponsored)* ACTERIA Prizes and EFIS-EJI Ita Askonas Prize

IS.01

15:30 – 15:45 15:45 – 16:00 16:00 – 16:15

S.A.02

16:15 – 16:30 Adaptive Immunity

Th17 Cells in Human 16:30 – 16:45 Health and Disease

S.B.02

Diseases Allergy and Asthma

WS.C.05

BS.D.1

Bright Sparks Immunotherapy

NK and NKT Cell Activation and Mechanisms

16:45 – 17:00

WS.D.02

Drug Immunogenicity and Biomarkers of Efficacy

WS.C.06

WS.A.03

WS.B.05

Innate Cell Signaling

17:00 – 17:15

Coffee Break

17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 18:00 – 18:15

S.C.02

18:15 – 18:30 Innate Immunity Mediators of 18:30 – 18:45 Inflammation 18:45 – 19:00

S.D.02

Disease Intervention Immunological Tolerance in Organ Transplantation

BS.A.1

Bright Sparks Adaptive Immunity

WS.B.04

Lymphocyte Targeting Immune Escape by Tumors

Molecular and Cellular Control of the Subsets

Local Tissue Alteration in Autoimmunity

19:00 – 19:15 19:15 – 19:30 19:30 – 19:45 19:45 – 20:00 20:00 – 20:15

SW.01

IS.04 (Industry Sponsored Titles to Figure (Industry Sponsored)* Progress in Legends: An Insider’s Technology Session)* Guide to Publishing IS.03

Scientific Writing Session

20:15 – 20:30 20:30 – 20:45 20:45 – 21:00 21:00 – 21:15 21:15 – 21:30

* please see page 97 for details

30

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

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Scientific Program

PROGRAM AT A GLANCE

Monday, Sept. 7, 2015 Hall M

Hall N

1

1

Meeting Room Meeting Room Meeting Room Meeting Room Meeting Room 1 2 3 5 6 (1.85-86) (1.61) (2.15) (2.17) (2.12) 1

1

2

2

2

ME.01

Room Level 07:15 – 08:15

Peter Openshaw

08:15 – 08:30 08:30 – 08:45

WS.C.03

Myeloid Suppressor Cells

08:45 – 09:00

WS.C.04

Dendritic Cells & Macrophages

09:00 – 09:15 09:15 – 09:30 09:30 – 09:45 09:45 – 10:00

Poster Session and Guided Poster Walks / Coffee Break

BA.10

BA.07

European Journal DGfI Study of Immunology Groups Editorial Board and Board Meeting Alumni Meeting

BA.08

BA.09

Dutch Society for Immunology (NVVI) Board Meeting

Scandinavian Society for Immunology (SSI) Council Meeting

10:00 – 10:15 10:15 – 10:30 10:30 – 10:45 10:45 – 11:00 11:00 – 11:15

WS.A.02

Germinal Centers: Genetic and Transcriptional Control

11:15 – 11:30

WS.B.03

11:30 – 11:45

Clinics, Pathophysiology and Genetics of Primary Immunodeficiency Diseases

11:45 – 12:00 12:00 – 12:15

BA.10.1

IUIS-Frontiers Partnership Meeting

12:15 – 12:30

BA.11

Scandinavian Society for Immunology (SSI) Retreat Follow-up Meeting

12:30 – 12:45 12:45 – 13:00 13:00 – 13:15 13:15 – 13:30 13:30 – 13:45 13:45 – 14:00 14:00 – 14:15

JS.03

14:15 – 14:30

Russian-GeorgianIS.02 Austrian Sister (Industry Symposium Sponsored)* From Magic Bullets

14:30 – 14:45 14:45 – 15:00

to Targeted Therapy Approaches

15:00 – 15:15 15:15 – 15:30 15:30 – 15:45

WS.D.03

15:45 – 16:00

BA.12

WS.D.04

16:00 – 16:15

IUIS-EFIS Annual Collaboration Review Meeting

Immune Preventive & Dissection of Anti- Therapeutic Viral Vaccines Approaches

16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 17:00 – 17:15

Coffee Break

BA.12.1

Italian Society of Immunology, Clinical Immunology and Allergology (SIICA) Board Meeting

BA.13 WS.A.04

Lymphocyte Subsets (part 1)

WS.A.05

Extrinsic Factors in the Control of B Cells

Scandinavian Journal of Immunology Editorial Board Meeting

17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 18:00 – 18:15 18:15 – 18:30 18:30 – 18:45 18:45 – 19:00 19:00 – 19:15

IS.05

(Industry Sponsored)*

BA.14

Italian Society of Immunology, Clinical Immunology and Allergology (SIICA) General Assembly

19:15 – 19:30

BA.15

19:30 – 19:45

Hungarian 19:45 – 20:00 Society for Immunology (MIT) 20:00 – 20:15 Board Meeting 20:15 – 20:30 20:30 – 20:45 20:45 – 21:00 21:00 – 21:15 21:15 – 21:30

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Scientific Program

PROGRAM AT A GLANCE

Tuesday, Sept. 8, 2015 Room

Hall A

Hall E

Hall F1

Hall F2

Hall G

Hall K

Level

2

0

0

0

-2

-2

07:15 – 08:15 08:15 – 08:30 08:30 – 08:45 08:45 – 09:00

S.A.03

Adaptive Immunity Immune Cell 09:15 – 09:30 Trafficking 09:00 – 09:15

S.B.03

Diseases Immunity Against Infections

WS.D.05

T Cell Based Cancer Immunotherapy

WS.C.07

Macrophage Signaling

WS.D.06

Stem Cells and CellBased Therapy

WS.C.08

Epigenetics in Innate Immunity

09:30 – 09:45 09:45 – 10:00 10:00 – 10:15 10:15 – 10:30

Poster Session and Guided Poster Walks / Coffee Break

10:30 – 10:45 10:45 – 11:00 11:00 – 11:15 11:15 – 11:30 11:30 – 11:45

S.C.03

11:45 – 12:00 Innate Immunity

Innate Effector

12:00 – 12:15 Functions

S.D.03

Disease Intervention Antibody Therapeutics

WS.A.06

Molecular & Cellular Control of CD8+ T Cells (part 2)

WS.B.06

Cytokines and Chemokines in Tumor Immunology

WS.A.07

WS.B.07

T Cell Signalling

Skin Diseases

12:15 – 12:30 12:30 – 12:45 12:45 – 13:00 13:00 – 13:15

KL.B.1

Diseases

13:15 – 13:30 Inflammasome 13:30 – 13:45 13:45 – 14:00 14:00 – 14:15

JS.04

14:15 – 14:30 International Union 14:30 – 14:45 14:45 – 15:00 15:00 – 15:15 15:15 – 15:30

of Immunological Societies (IUIS) Vaccine Development Can Benefit from Computational Biology

JS.05

European Academy of Allergy and IS.07 Clinical Immunology (Industry Sponsored)* (EAACI) T Helper Cell Subsets in Health and Disease

JS.06

International Society for the Advancement of Cytometry (ISAC) Cytometry of the 21st Century

JS.07

Society for Mucosal Immunity (SMI) The Mucosal Microbiome in Health and Disease

15:30 – 15:45 15:45 – 16:00 16:00 – 16:15

S.A.04

16:15 – 16:30 Adaptive Immunity

Establishment of 16:30 – 16:45 B Cell Responses

S.B.04

Diseases Primary Immunodeficiencies

WS.D.07

Novel Approaches for Vaccines

WS.C.10

Macrophages in Diseases

WS.C.11

WS.B.09

WS.B.11

WS.A.11

Innate Lymphoid Cells

Optimizing Anti‑Tumor Immunity

16:45 – 17:00 17:00 – 17:15

Coffee Break

17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 18:00 – 18:15

S.C.04

18:15 – 18:30 Innate Immunity

Antigen Uptake and

18:30 – 18:45 Presentation

S.D.04

Disease Intervention Cancer Immunotherapy

WS.A.10

WS.B.10

Treg Induction / Subsets

Systemic Autoimmune Diseases

Allergens

B Cell Signaling

18:45 – 19:00 19:00 – 19:15 19:15 – 19:30 19:30 – 19:45 19:45 – 20:00 20:00 – 20:15 20:15 – 20:30

Heurigen Evening

20:30 – 20:45 20:45 – 21:00 21:00 – 21:15 21:15 – 21:30

* please see page 99 for details

32

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

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Scientific Program

PROGRAM AT A GLANCE

Tuesday, Sept. 8, 2015 Hall M

Hall N

1

1

Meeting Room Meeting Room Meeting Room Meeting Room 1 3 5 6 (1.85-86) (2.15) (2.17) (2.12) 1

ME.02

Jürgen Wienands

2

ME.03

Ron Germain

2

ME.04

Nadine Cerf-Bensussan

2

L7

Room

1

Level

ME.05

07:15 – 08:15

Luke O’Neill

08:15 – 08:30 08:30 – 08:45

WS.C.09

WS.E.01

Structural Biology and Imaging

08:45 – 09:00

Innate Cell Signalling & Function

09:00 – 09:15 09:15 – 09:30 09:30 – 09:45 09:45 – 10:00

Poster Session IS.06 BA.16 BA.17 BA.19 and Scandinavian German Society Belgian (Industry BA.18 Guided Sponsored Progress Society for for Immunology Immunological French Society of BA.19.1 Immunology (SSI) (DGfI) Society (BIS) Poster Walks / in Technology Immunology (SFI) IUIS Quality Session)* General Assembly General Assembly General Assembly Coffee Break Annual board Assessment and meeting

WS.A.08

B Cell Development & Homeostasis

WS.B.08

Standardization Committee Meeting

10:00 – 10:15 10:15 – 10:30 10:30 – 10:45 10:45 – 11:00 11:00 – 11:15 11:15 – 11:30 11:30 – 11:45

Innate Immune Mechanisms in Cancer

11:45 – 12:00 12:00 – 12:15 12:15 – 12:30 12:30 – 12:45

BA.20

12:45 – 13:00

EEIG ECI-EFIS Meeting

13:00 – 13:15 13:15 – 13:30 13:30 – 13:45 13:45 – 14:00 14:00 – 14:15

WO.00

Women in Immunology Carreer Talks

BA.21

EFIS General Assembly

WS.A.09

Molecular Control of T Cell Development

WS.D.08

Solid Organ and Bone Marrow Transplantation

Coffee Break

14:30 – 14:45 14:45 – 15:00 15:00 – 15:15 15:15 – 15:30 15:30 – 15:45 15:45 – 16:00 16:00 – 16:15 16:15 – 16:30

BA.22

Inaugural IUIS Vaccine Committee Meeting

16:30 – 16:45 16:45 – 17:00 17:00 – 17:15

BA.23

EFIS Board Meeting

17:15 – 17:30 17:30 – 17:45 17:45 – 18:00

WS.B.12

Models and Mechanisms of Primary Immunodeficiency

booked out!

14:15 – 14:30

18:00 – 18:15

WS.B.13

18:15 – 18:30

Immune Disorders

18:30 – 18:45 18:45 – 19:00 19:00 – 19:15 19:15 – 19:30 19:30 – 19:45 19:45 – 20:00

Heurigen Evening

20:00 – 20:15 20:15 – 20:30 20:30 – 20:45 20:45 – 21:00 21:00 – 21:15 21:15 – 21:30

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Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

33

Scientific Program

PROGRAM AT A GLANCE

Wednesday, Sept. 9, 2015 Room

Hall A

Hall E

Hall F1

Hall F2

Hall G

Hall K

Level

2

0

0

0

-2

-2

07:15 – 08:15 08:15 – 08:30 08:30 – 08:45 08:45 – 09:00

S.A.05

Adaptive Immunity

09:00 – 09:15 Maintenance 09:15 – 09:30 09:30 – 09:45

of Lymphocyte Memory

S.B.05

Diseases Autoimmunity

WS.D.09

WS.C.12 Cancer Dendritic Cell Immunotherapy and Differentiation and Anti-Tumor Vaccines Function

WS.D.10

WS.C.13

Intervention and Therapy of Allergy

Mast Cells

09:45 – 10:00 10:00 – 10:15

EP.01

1st EFIS President's Symposium 10:30 – 10:45 On NK Cells and NK Cell-Based Therapy 10:45 – 11:00 of Leukemias 10:15 – 10:30

Poster Session and Guided Poster Walks / Coffee Break

11:00 – 11:15 11:15 – 11:30 11:30 – 11:45

S.C.05

Innate Immunity

11:45 – 12:00 Innate Lymphocytes 12:00 – 12:15 - Backstage or 12:15 – 12:30

Centerstage

S.D.05

Disease Intervention T Cell Mediated Immunotherapy

WS.A.12

Molecular & Cellular Control of CD8+ T Cells (part 3)

WS.B.14

WS.B.15 Immune Recognition Immune Regulation and Control of at the Intestinal Infections Barrier

WS.B.16

Mediators of Airway Inflammation

12:30 – 12:45 12:45 – 13:00 13:00 – 13:15 13:15 – 13:30

JS.08

KL.D.1

World Allergy Association (WAO) Mechanisms in Allergy

Disease Intervention 13:30 – 13:45 Cancer Therapy 13:45 – 14:00 14:00 – 14:15

JS.09

European Society for Immunodeficiencies (ESID) Newborn Screening for Immunodeficiency

14:15 – 14:30 14:30 – 14:45 14:45 – 15:00 15:00 – 15:15

S.A.06

Adaptive Immunity 15:15 – 15:30 Molecular Switches 15:30 – 15:45 in Adaptive Immunity 15:45 – 16:00

S.B.06

Diseases Stroma - Immune Interactions in Cancer and Inflammation

WS.D.12

Immune Intervention in Autoimmune Diseases

WS.C.15

WS.A.15

WS.D.13

WS.A.16

WS.B.19

WS.B.20

Dendritic Cell Subsets

Treg Function / Biology

Immunotherapy of Infectious Diseases

16:00 – 16:15 16:15 – 16:30 16:30 – 16:45

S.C.06

16:45 – 17:00 Innate Immunity

S.D.06

Disease Intervention Inhibitory and Aging and the 17:00 – 17:15 Activating Receptors Immune System

WS.B.18

Tumor Biology and Immunosurveillance

Looking at the "States and Fates of T Cells"

Immune Modulation by Infectious Agents

HIV Infection and Immune Control

17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 18:00 – 18:15 18:15 – 18:30

Closing and Award Ceremony

18:30 – 18:45 18:45 – 19:00 19:00 – 19:15 19:15 – 19:30 19:30 – 19:45 19:45 – 20:00 20:00 – 20:15 20:15 – 20:30 20:30 – 20:45 20:45 – 21:00 21:00 – 21:15 21:15 – 21:30

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ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

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Scientific Program

PROGRAM AT A GLANCE

Wednesday, Sept. 9, 2015 Hall M

Hall N

Meeting Room 1 (1.85-86)

1

1

1

Meeting Room 2 (1.61)

Room

1

Level

ME.06

Mirjam Heemskerk

07:15 – 08:15 08:15 – 08:30 08:30 – 08:45

WS.C.14

NK and NKT Cell Function

08:45 – 09:00

WS.D.11

Imaging & cancer therapy

09:00 – 09:15 09:15 – 09:30 09:30 – 09:45 09:45 – 10:00 10:00 – 10:15

Poster Session and Guided Poster Walks / Coffee Break

10:15 – 10:30 10:30 – 10:45 10:45 – 11:00 11:00 – 11:15 11:15 – 11:30

WS.A.13

Lymphocyte Subsets (part 2)

WS.A.14

T Cell Mediated Control of GC Reactions

11:30 – 11:45

Scientific Satellite Meeting IUIS The Importance of Standardization for Immunology

WO.01

11:45 – 12:00 12:00 – 12:15 12:15 – 12:30 12:30 – 12:45 12:45 – 13:00 13:00 – 13:15 13:15 – 13:30

Women in Immunology She is a genius

13:30 – 13:45 13:45 – 14:00 14:00 – 14:15 14:15 – 14:30 14:30 – 14:45 14:45 – 15:00

WS.E.02

Metabolism & Immunity

15:00 – 15:15

WS.B.17

15:15 – 15:30

Immune Dysregulation

15:30 – 15:45 15:45 – 16:00 16:00 – 16:15

WS.A.17

Extrinsic and Intrinsic Control of Positive/ Negative T Cell Selection

WS.A.18

Germinal Centers: Survival & Differentiation Signals

BA.23.1

Österreichische Gesellschaft für Allergologie und Immunologie (ÖGAI) Board Meeting (Vorstandssitzung)

16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 17:00 – 17:15 17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 18:00 – 18:15 18:15 – 18:30 18:30 – 18:45 18:45 – 19:00 19:00 – 19:15

BA.24

Österreichische Gesellschaft für Allergologie und Immunologie (ÖGAI) General Assembly (Generalversammlung)

19:15 – 19:30 19:30 – 19:45 19:45 – 20:00 20:00 – 20:15 20:15 – 20:30 20:30 – 20:45 20:45 – 21:00 21:00 – 21:15 21:15 – 21:30

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Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Scientific Program

HOW TO READ THE SCIENTIFIC PROGRAM ECI 2015 CONTENT TRACKS The scientific program of the ECI 2015 has been structured into four main tracks: Track A – Adaptive Immunity Track B – Diseases of the Immune System Track C – Innate Immunity Track D – Disease Intervention Additionally a fifth track (Track E) combining topics which do not fit within the four main tracks was introduced. The 4-track program will streamline keynote lectures, symposia, workshops as well as guided poster walks in a way that will promote easy cross talk between the basic topics and types of sessions planned.

SESSION TYPE DESCRIPTION Some sessions fill up quickly. Arrive early to guarantee your entry and avoid disappointment!

Invited Program Keynote Lectures (KL.A.1 / KL.B.1 / KL.C.1 / KL.D.1) The keynote lectures are the most prestigious sessions of the congress. These are exhaustive reviews of major subjects and state of the art techniques within the field, addressed to all participants. Speakers in keynote lectures are invited and are among the most renowned in their field of expertise. Keynote lectures are scheduled at “prime time” in the program in order to achieve maximal attendance. EFIS President`s Symposium (EP.01) The EFIS President`s Symposium is a newly introduced format which will focus on the research area of the current EFIS president. EFIS Awards Lectures (EF.01) The work of the laureate of the EFIS/EJI Ita Askonas Award as well as the Acteria Prize winners (ACTERIA Doctoral Thesis Prizes and ACTERIA Early Career Research Prizes) are presented within this session. EFIS-IL Awards Poster Presentations (EFIS-IL.01-02) The awards were established by the European Federation of Immunological Societies (EFIS) with general support from Immunology Letters, in order to recognize the most often cited original paper and review, respectively, within the first 3 years after publication, published in Immunology Letters. Symposia (S.A.01-06 / S.B.01-06 / S.C.01-06 / S.D.01-06) The symposia are state-of the art educational sessions in which invited speakers share their newest results with other researchers on a given topic. The aim is to reflect and compare data with other perhaps contradictory results and to discuss new hypotheses and concepts for further research with well-established colleagues. In every concurrent symposium three 20+5-minute lectures will be presented that provide an update and understanding of new developments and innovations in a certain research area. Women in Immunology (WO.01) Gender imbalance in science (and society) is a long-standing issue that has moved into the spotlight in the European Union in recent years. This symposium highlights the historical perspective of exclusion of women in science and discusses the current situation of women in immunology. The symposium is supposed to increase visibility of women and their achievements in science and especially within the field of immunology. A round table with all speakers and chairpersons will discuss the most important points raised during the presentations, the most urgent goals and the most achievable goals as well as the means to achieve these goals. Scientific Writing Session (SW.01) This session, which is dedicated primarily for PhD or MD students/early postdocs, will provide examples and tips of good scientific writing.

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ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

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Scientific Program

HOW TO READ THE SCIENTIFIC PROGRAM

Joint Symposia (JS.01-09) Joint symposia are sessions in which the ECI joins forces with important international scientific societies to facilitate knowledge transfer and bring researchers from related disciplines and/or different continents together in order to foster exchange and networking across all borders. Joint society symposia consist of 3 speakers (30 minutes per talk) on a topic nominated by the partner society. Meet the Professor Breakfasts (ME.01-06) Informal breakfast event for early career scientists. The “Meet the Professor Breakfasts” will provide participants the opportunity to meet the most renowned senior scientists in an interactive and casual manner. Small breakfast will be provided. Registration is possible via email and onsite at a first-come-first-serve basis. Maximum amount of participants per breakfast: 30

Submitted Program Bright Sparks Workshops (BS.A.1 / BS.B.1 / BS.C.1 / BS.D.1) The most notable and exciting work from abstracts submitted to the congress by early career scientists will be honored with an oral presentation in one of the Bright Sparks Workshops. Presenters are expected to explain their work and answer questions from the audience. Workshops (WS.A.01-18 / WS:B.01-20 / WS.C.01-15 / WS.D.01-13 / WS.E.01-02) The most notable and exciting work from all abstracts submitted to the congress will be honored with an oral presentation in these sessions. Presenters are expected to explain their work and answer questions from the audience. Guided Poster Sessions (P.A.01-28 / P.B.01-42 / P.C.01-24 / P.D.01-27 / P.E.01-05) Posters are numerically the major scientific presentations of the meeting. The majority of congress attendees present a poster showing data and progress with their personal research. Posters offer an excellent opportunity for people interested in a particular topic to meet and exchange ideas and network with other researchers. Posters should NOT be used to advertise a product or service. Like a paper, a poster abstract should detail the focus of the presentation and the way(s) in which it contributes to the body of knowledge in its field. Guided Poster Sessions (Monday, Tuesday and Wednesday from 09:45 to 11:15) will be chaired by ECI faculty members and senior researchers within the respective areas and should be used for communication and interaction with the poster presenters, who are requested to be at their posters at these times. Track A Adaptive Immunity

Track B Diseases

Track C Innate Immunity

Track D Disease Intervention

Track E Other

Monday

P.A.01 - 10

P.B.01 - 14

P.C.01 - 08

P.D.01 - 10

P.E.01

Tuesday

P.A.11 - 19

P.B.15 - 28

P.C.09 - 16

P.D.11 - 18

P.E.02 - 03

Wednesday

P.A.20 - 28

P.B.29 - 42

P.C.17 - 24

P.D.19 - 27

P.E.04 - 05

The chairpersons of the guided poster sessions will also evaluate all posters and will select the candidates for the ECI 2015 Poster Awards. Based on their evaluations a designated award jury will then select the awardees to receive the ECI 2015 Poster Awards. Schedule for display, mounting and removal Posters will be changed every day. Each poster will be on display during one of the following days: Monday, September 7 08:30 – 18:00 hrs Tuesday, September 8 08:30 – 18:00 hrs Wednesday, September 9 08:30 – 16:00 hrs Poster mounting on the respective days will be possible between 07:30 – 08:30 hrs strict. Posters need to be removed on the day of presentation between 18:00 – 19:30 hrs strict (16:00 – 17:45 hrs on Wednesday). Access after 19:30 hrs (17:45 hrs on Wednesday) is not possible! Posters not removed until 19:30 hrs on the day of presentation (17:45 hrs on Wednesday), will be taken down by the staff of the congress venue and will not be stored or sent to the authors after the meeting. All detailed information on the Guided Poster Sessions can be found in the separate poster information booklet.

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Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Scientific Program

HOW TO READ THE SCIENTIFIC PROGRAM

Sponsored Program Industry Sponsored (Lunch) Symposia (IS.01-07) Sponsors are approved as reputable and relevant by the Scientific Program Committee, but the detailed content of the presentations is proposed directly by the sponsors and under their responsibility. The organizers are not endorsing the content in any way.

Other Sessions and Meetings Business and Ancillary Meetings (BA.01-24) Business Meetings of scientific associations (e.g. general assemblies, board meetings) are generally meetings open to a designated group of individuals and are mostly on invitation only. Business meetings of scientific associations in conjunction with the ECI 2015 can be held during the congress opening hours as preferred by the respective organizer(s). Please note that all participants of business meetings must also be registered participants of the ECI 2015 as there will be a centrally located access control. Educational Courses / Scientific Satellite Meetings The 4th European Congress of Immunology generally welcomes non-commercial educational courses and scientific satellites around the ECI congress. Those are “open” meetings being of interest to the general ECI audience, going from a few hours to 1-2 days, scheduled ahead or on and after the last day of the ECI congress. Satellite meetings are organized by individuals and/or scientific associations and must conform to established criteria if they are to be associated with the ECI 2015. Approval by the congress president and the president of the scientific program committee is required for a meeting to be granted satellite status.

HOW TO READ THE PRESENTATION NUMBERS How to read the presentation numbers – for example: WS.B.02.5 WS.B.02.5: BS: EF: EP: IS: JS: KL:

WS stands for one of the following session types (in alphabetical order):

Bright Sparks Workshop EFIS Award Lecture EFIS President’s Symposium Industry Sponsored Symposium Joint Symposium Keynote Lecture

ME: P: S: SW: WO: WS:

Meet the Professor Breakfast Guided Poster Walks Symposia Scientific Writing Women in Immunology Workshop

WS.B.02.5: B stands for one of the following tracks: A: B: C: D: E:

Adaptive Immunity Diseases Innate Immunity Disease Intervention Other Topics

WS.B.02.5: 02 indicates the chronological order within the session type and track WS.B.02.5:

5 indicates the chronological order of presentation within the respective session

OTHER MEETINGS: BA: Business and Ancillary Meetings ES: Educational Courses and Scientific Satellite Meetings

38

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

NEED INFORMATION ON THE ECI CONGRESS 2015 AT YOUR FINGERTIPS?

THERE`S AN APP FOR THAT

Download the ECI 2015 app today and stay up-to-date during the 2015 Congress • Regular updates to the scientific programme • Practical information about the venue • Find exhibitors easily • Download using the free WiFi in the Austria Center: search your app store for “ECI 2015”

Scientific Program

RELATED PRE-CONGRESSIONAL EVENTS IN VIENNA BEFORE THE START OF THE 4TH ECI CONGRESS September 02 - 05, 2015 September 02, 2015

September 03, 2015

September 04, 2015

September 05, 2015

LUPUS 2015 September 02-06,2015 HOFBURG Vienna Congress Center Heldenplatz, Vienna, Austria

European Veterinary Immunology Workshop September 02-04, 2015 University of Veterinary Medicine (Vetmeduni Vienna), Veterinaerplatz 1, 1210 Vienna

 

 

 

7. Wiener Komponentenschule September 04-05, 2015 (Meeting Language = German) Hotel Nestroy Wien, Rotensterngasse 10, 1020 Vienna

 

 

 

Scientific Satellite Meeting Immunosenescence: Hot Topics and Interventions September 05-06, 2015 L2, Austria Center Vienna

 

 

 

BA.01 13:00 – 16:30 ABIRISK EPMT Meeting Meeting Room 2 (1.61), ACV

CONGRESSES September 02 - 06, 2015 LUPUS 2015 (Pre - Registration required) HOFBURG Vienna Congress Center, Heldenplatz, Vienna

EDUCATIONAL COURSES & SCIENTIFIC SATELLITE SYMPOSIA September 02 - 04, 2015 European Veterinary Immunology Workshop (Pre - Registration required) University of Veterinary Medicine (Vetmeduni Vienna), Veterinaerplatz 1, 1210 Vienna

BUSINESS AND ANCILLARY MEETINGS September 05, 2015 nnBA.01

ABIRISK EPMT Meeting

closed*

Meeting Room 2 (1.61) 13:00 – 16:30

* on invitation only

September 04 - 05, 2015 7. Wiener Komponentenschule / 7th Vienna School on Allgergy – Components (Meeting Language = German) (Pre - Registration required) Hotel Nestroy Wien, Rotensterngasse 10, 1020 Vienna September 05 - 06, 2015 Immunosenescence: Hot Topics and Interventions (Pre - Registration required) L2, Austria Center Vienna

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ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

SUNDAY

SUNDAY Schedule at a Glance Sunday. . . . . . . . . . . . . . . . . . . . . . . . . 42 Opening Ceremony. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43 Keynote Lecture of the Day . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 Opening of Historic Exhibition “Emerging Immunology – Vienna’s Contribution” . . . . . . . . . 43 Educational Courses & Scientific Satellite Symposia . . . . . . . 44 Business and Ancillary Meetings. . . . . . . . . . . . . . . . . . . . . . . . 44

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Program per Day

SUNDAY, SEPT. 6, 2015 SCHEDULE AT A GLANCE SUNDAY

SUNDAY

Sunday, Sept. 6, 2015 Room

Hall A

L2

L1

L8

Meeting Room 1 (1.85-86)

Meeting Room 2 (1.61)

Level

2

1

1

1

1

1

07:30 – 07:45 07:45 – 08:00 08:00 – 08:15 08:15 – 08:30 08:30 – 08:45 08:45 – 09:00 09:00 – 09:15 09:15 – 09:30 09:30 – 09:45

BA.02

09:45 – 10:00

IUIS Executive Committee Meeting

10:00 – 10:15 10:15 – 10:30 10:30 – 10:45 10:45 – 11:00 11:00 – 11:15 11:15 – 11:30 11:30 – 11:45 11:45 – 12:00 12:00 – 12:15

Scientific Satellite Meeting

Educational Course

Immunosenescence: Hot Topics and Interventions - Day 2

Advanced Cytometry Course

12:15 – 12:30 12:30 – 12:45 12:45 – 13:00 13:00 – 13:15

BA.04

ABIRISK Steering Committee (SC) Meeting

13:15 – 13:30 13:30 – 13:45 13:45 – 14:00 14:00 – 14:15

BA.05

14:15 – 14:30

German Society for Immunology (DGfI) Board Meeting

14:30 – 14:45 14:45 – 15:00 15:00 – 15:15 15:15 – 15:30 15:30 – 15:45

Scientific Satellite Meeting ABIRISK - Immune Reactions Against Biopharmaceuticals

15:45 – 16:00 16:00 – 16:15 16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 17:00 – 17:15 17:15 – 17:30 17:30 – 17:45

Opening Ceremony

17:45 – 18:00 18:00 – 18:15

KL.A.1

18:15 – 18:30 Adaptive Immunity The B Cell Receptor in B

18:30 – 18:45 Cell Development, Memory 18:45 – 19:00 and Malignancies 19:00 – 19:15

Opening of Historic Exhibition “Emerging Immunology – Vienna’s Contribution”

19:15 – 19:30 19:30 – 19:45 19:45 – 20:00 20:00 – 20:15 20:15 – 20:30

Networking Mixer

20:30 – 20:45 20:45 – 21:00 21:00 – 22:00

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ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

SUNDAY, SEPT. 6, 2015 SCHEDULE AT A GLANCE SUNDAY OPENING CEREMONY

Meeting Room 5 (2.17)

Meeting Room 8 (1.62)

2

1

Room Level 07:30 – 07:45 07:45 – 08:00 08:00 – 08:15 08:15 – 08:30 08:30 – 08:45 08:45 – 09:00 09:00 – 09:15 09:15 – 09:30 09:30 – 09:45 09:45 – 10:00 10:00 – 10:15 10:15 – 10:30

BA.03

10:30 – 10:45

SysmedIBD Consortium Meeting

10:45 – 11:00 11:00 – 11:15 11:15 – 11:30 11:30 – 11:45 11:45 – 12:00 12:00 – 12:15 12:15 – 12:30 12:30 – 12:45 12:45 – 13:00 13:00 – 13:15 13:15 – 13:30 13:30 – 13:45 13:45 – 14:00 14:00 – 14:15

Scientific Satellite Meeting Get to know SysmedIBD (EU-FP7 Project Systems Medicine of Chronic Inflammatory Bowel Disease)

BA.06

14:15 – 14:30

British Society for Immunology (BSI) Programme Committee Meeting

14:30 – 14:45 14:45 – 15:00

Ludwig van Beethoven (1770-1827) Tempo di Menuetto quasi allegretto WoO 3 "Gratulations-Menuett" Welcome message by the 4th ECI Congress President Winfried F. Pickl Franz Schubert (1797-1828) Polonaise für Violine und Orchester D 580 Welcome message by the EFIS President Lorenzo Moretta Wolfgang Amadeus Mozart (1756-1791) Sinfonie in D KV 385 "Haffner-Sinfonie" I. Allegro con spirito II. Andante III. Menuetto IV. Presto Keynote Lecture Klaus Rajewsky The B cell receptor in B cell development, memory and malignancies Johann Strauß Vater (1804-1849) Jubel-Quadrille op. 130 Music: Klangvereinigung Wien Orchestra Conductor: Michael Zlabinger After his studies in Vienna and Lucerne, the young Austrian conductor Michael Zlabinger has been working at the Salzburg Festival, Wiener Staatsoper, Opernhaus Zürich, Teatro alla Scala di Milano and Grand Théatre de Genève. He has conducted opera, ballet and symphonic repertoire from baroque to the 21st century.

15:15 – 15:30 15:30 – 15:45 15:45 – 16:00 16:00 – 16:15

OPENING OF HISTORIC EXHIBITION “EMERGING IMMUNOLOGY – VIENNA’S CONTRIBUTION”

16:30 – 16:45

19:00

16:45 – 17:00

Opening by: Lorenzo Moretta

17:00 – 17:15

In the presence of the curators: Johann Eibl, Othmar Förster

17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 18:00 – 18:15 18:15 – 18:30 18:30 – 18:45 18:45 – 19:00 19:00 – 19:15 19:15 – 19:30 19:30 – 19:45 19:45 – 20:00

Networking Mixer

Hall A

15:00 – 15:15

16:15 – 16:30

Opening of Historic Exhibition

17:00 – 18:00

SUNDAY

Sunday, Sept. 6, 2015

20:00 – 20:15 20:15 – 20:30

Level 0 / Main Foyer

Come and join us for the opening of the exhibition “Emerging Immunology – Vienna’s Contribution”. Vienna has been a cradle of immunology research at the end of the 19th beginning of the 20th century. Some of the outstanding Austrian immunologists - from Karl Landsteiner to Clemens von Pirquet including their colleagues and contemporaries - will be commemorated in this exhibition, which has been curated by Johann Eibl, Othmar Förster and Winfried F. Pickl. Moreover, a short outlook describing major immunology research centers in the Vienna area in the 21st century will be provided.

20:30 – 20:45 20:45 – 21:00 21:00 – 22:00

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Program per Day

SUNDAY, SEPT. 6, 2015

Keynote Lecture of the Day - KL.A.1 – Innate Immunity 18:00 – 19:00 Chairperson:

Hall A Winfried Pickl; Vienna, Austria

The B cell receptor in B cell development, memory and malignancies

SUNDAY

Klaus Rajewsky Max-Delbrück-Center for Molecular Medicine Immune Regulation and Cancer; Berlin, Germany Klaus Rajewsky and collaborators developed a general method of targeted mutagenesis in mouse embryonic stem cells by introducing bacteriophage- and yeast-derived recombination systems, which opened the way for conditional gene targeting. Using this and other methods in their immunological work, they developed, together with N. A. Mitchison and N. K. Jerne, the antigen-bridge model of T-B cell cooperation, identified germinal centers as the sites of antibody somatic hypermutation, the B cell antigen receptor as a survival determinant of B cells, and the germinal center as a major site of human B cell lymphomagenesis, including Hodgkin lymphoma. Over the last years the work of his group has focused on mechanisms of microRNA control and the development of mouse models of human B cell lymphomas. Klaus Rajewsky obtained his degree in medicine (MD) at the University of Frankfurt in 1962. After postdoctoral work at the Institut Pasteur in Paris he built an immunology department at the Institute for Genetics at the University of Cologne where he stayed for 38 years, was the founding Program Coordinator of the EMBL Mouse Biology Program at Monterotondo near Rome, worked for 10 years at Harvard Medical School in Boston, and is since 2012 at the Max-Delbrück-Center for Molecular Medicine in Berlin. Klaus Rajewsky won numerous scientific awards and is a member of several learned societies including the National Academy of Sciences of the USA and the American Academy of Arts and Sciences.

EDUCATIONAL COURSES & SCIENTIFIC SATELLITE SYMPOSIA

BUSINESS AND ANCILLARY MEETINGS nnBA.02

nnImmunosenescence: Hot Topics and Interventions (Registration required)

L2

08:30 – 16:00 (Day 2)

nnABIRISK - Immune Reactions against Biopharmaceuticals

L1

closed* nnBA.03

Attendance is free of charge – no registration required!

15:30 – 16:30

closed*

nnAdvanced Cytometry Course

L8

nnBA.04

09.00 – 16.00

closed*

(Registration required) nnGet to know SysmedIBD Attendance is free of charge – no registration required!

Meeting Room 5 (2.17) 13:30 – 17:00

IUIS Executive Committee Meeting

nnBA.05

Meeting Room 2 (1.61) 07:30 – 12:30 SysmedIBD Consortium Meeting Meeting Room 5 (2.17) 08:00 – 13:30 ABIRISK Steering Committee (SC) Meeting Meeting Room 1 (1.85-86) 09:00 – 15:30 German Society for Immunology (DGfI)

closed* Board Meeting nnBA.06

Meeting Room 2 (1.61) 13:00 – 16:00

British Society for Immunology (BSI)

closed* Programme Committee Meeting

Meeting Room 8 (1.62) 13:00 – 16:30

* on invitation only

44

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

MONDAY

MONDAY Schedule at a Glance Monday . . . . . . . . . . . . . . . . . . . . . . . . 46 Keynote Lecture of the Day . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 Overview per Track. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 Track A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 Track B . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 Track C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53 Track D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56 Joint-Symposia of the Day. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 Other Sessions and Meetings. . . . . . . . . . . . . . . . . . . . . . . . . . . 58 Business and Ancillary Meetings. . . . . . . . . . . . . . . . . . . . . . . . 59 Meet the Professor Breakfast. . . . . . . . . . . . . . . . . . . . . . . . . . . 59 Posters of the Day according to Tracks A, B, C, D, E . . . . . . . 60

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

45

Program per Day

MONDAY, SEPT. 7, 2015 SCHEDULE AT A GLANCE MONDAY

Monday, Sept. 7, 2015 Room

Hall A

Hall E

Hall F1

Hall F2

Hall G

Hall K

Level

2

0

0

0

-2

-2

07:15 – 08:15 08:15 – 08:30 08:30 – 08:45 08:45 – 09:00

S.A.01

Adaptive Immunity Protection by CD8 09:15 – 09:30 T Cells 09:00 – 09:15

S.B.01

Diseases Chronic Inflammation

BS.C.1

Bright Sparks Breakthroughs in Innate Immunity

WS.D.01

Immunosuppresive Therapies and Immunomodulation

WS.C.01

WS.C.02 Leukocyte Trafficking Innate Sensors

09:30 – 09:45 09:45 – 10:00

MONDAY

10:00 – 10:15 10:15 – 10:30

Poster Session and Guided Poster Walks / Coffee Break

10:30 – 10:45 10:45 – 11:00 11:00 – 11:15 11:15 – 11:30 11:30 – 11:45

S.C.01

11:45 – 12:00 Innate Immunity

12:00 – 12:15 Mucosal Immunity

S.D.01

Disease Intervention Vaccines

12:15 – 12:30

BS.B.1

Bright Sparks Insights in Immunological Disease Mechanisms

WS.A.01

Molecular & Cellular Control of CD8+ T Cells (part 1)

WS.B.02

WS.B.01

Generation of Allergen Specific Immune Responses

Control of Inflammation in Autoimmune Diseases

12:30 – 12:45 12:45 – 13:00

KL.C.1

13:00 – 13:15 Innate Immunity

Intestinal

13:15 – 13:30 Homeostasis and its 13:30 – 13:45 Breakdown 13:45 – 14:00 14:00 – 14:15

JS.01

14:15 – 14:30 American

Association of Immunologists (AAI) 14:45 – 15:00 Molecular Mechanisms of the 15:00 – 15:15 Immune Response to 15:15 – 15:30 Infection 14:30 – 14:45

JS.02

European League Against Rheumatism (EULAR) Resolution of Inflammation

EF.01

EFIS Awards Lecture Symposium (Industry Sponsored)* ACTERIA Prizes and EFIS-EJI Ita Askonas Prize

IS.01

15:30 – 15:45 15:45 – 16:00 16:00 – 16:15

S.A.02

16:15 – 16:30 Adaptive Immunity

Th17 Cells in Human 16:30 – 16:45 Health and Disease

S.B.02

Diseases Allergy and Asthma

WS.C.05

BS.D.1

Bright Sparks Immunotherapy

NK and NKT Cell Activation and Mechanisms

16:45 – 17:00

WS.D.02

Drug Immunogenicity and Biomarkers of Efficacy

WS.C.06

WS.A.03

WS.B.05

Innate Cell Signaling

17:00 – 17:15

Coffee Break

17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 18:00 – 18:15

S.C.02

18:15 – 18:30 Innate Immunity Mediators of 18:30 – 18:45 Inflammation 18:45 – 19:00

S.D.02

Disease Intervention Immunological Tolerance in Organ Transplantation

BS.A.1

Bright Sparks Adaptive Immunity

WS.B.04

Lymphocyte Targeting Immune Escape by Tumors

Molecular and Cellular Control of the Subsets

Local Tissue Alteration in Autoimmunity

19:00 – 19:15 19:15 – 19:30 19:30 – 19:45 19:45 – 20:00 20:00 – 20:15

SW.01

IS.04 (Industry Sponsored Titles to Figure (Industry Sponsored)* Progress in Legends: An Insider’s Technology Session)* Guide to Publishing IS.03

Scientific Writing Session

20:15 – 20:30 20:30 – 20:45 20:45 – 21:00 21:00 – 21:15 21:15 – 21:30

* please see page 97 for details

46

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

MONDAY, SEPT. 7, 2015 SCHEDULE AT A GLANCE MONDAY

Monday, Sept. 7, 2015 Hall M

Hall N

1

1

Meeting Room Meeting Room Meeting Room Meeting Room Meeting Room 1 2 3 5 6 (1.85-86) (1.61) (2.15) (2.17) (2.12) 1

1

2

2

2

ME.01

Room Level 07:15 – 08:15

Peter Openshaw

08:15 – 08:30 08:30 – 08:45

WS.C.03

Myeloid Suppressor Cells

08:45 – 09:00

WS.C.04

Dendritic Cells & Macrophages

09:00 – 09:15 09:15 – 09:30 09:30 – 09:45 09:45 – 10:00

BA.07

European Journal DGfI Study of Immunology Groups Editorial Board and Board Meeting Alumni Meeting

BA.08

BA.09

Dutch Society for Immunology (NVVI) Board Meeting

Scandinavian Society for Immunology (SSI) Council Meeting

10:00 – 10:15 10:15 – 10:30 10:30 – 10:45 10:45 – 11:00 11:00 – 11:15

WS.A.02

Germinal Centers: Genetic and Transcriptional Control

11:15 – 11:30

WS.B.03

11:30 – 11:45

Clinics, Pathophysiology and Genetics of Primary Immunodeficiency Diseases

11:45 – 12:00 12:00 – 12:15

BA.10.1

IUIS-Frontiers Partnership Meeting

12:15 – 12:30

BA.11

Scandinavian Society for Immunology (SSI) Retreat Follow-up Meeting

12:30 – 12:45 12:45 – 13:00 13:00 – 13:15 13:15 – 13:30 13:30 – 13:45 13:45 – 14:00 14:00 – 14:15

JS.03

14:15 – 14:30

Russian-GeorgianIS.02 Austrian Sister (Industry Symposium Sponsored)* From Magic Bullets

14:30 – 14:45 14:45 – 15:00

to Targeted Therapy Approaches

15:00 – 15:15 15:15 – 15:30 15:30 – 15:45

WS.D.03

15:45 – 16:00

BA.12

WS.D.04

16:00 – 16:15

IUIS-EFIS Annual Collaboration Review Meeting

Immune Preventive & Dissection of Anti- Therapeutic Viral Vaccines Approaches

16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 17:00 – 17:15

Coffee Break

BA.12.1

Italian Society of Immunology, Clinical Immunology and Allergology (SIICA) Board Meeting

BA.13 WS.A.04

Lymphocyte Subsets (part 1)

WS.A.05

Extrinsic Factors in the Control of B Cells

Scandinavian Journal of Immunology Editorial Board Meeting

17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 18:00 – 18:15 18:15 – 18:30 18:30 – 18:45 18:45 – 19:00 19:00 – 19:15

IS.05

(Industry Sponsored)*

BA.14

Italian Society of Immunology, Clinical Immunology and Allergology (SIICA) General Assembly

19:15 – 19:30

BA.15

19:30 – 19:45

Hungarian 19:45 – 20:00 Society for Immunology (MIT) 20:00 – 20:15 Board Meeting 20:15 – 20:30 20:30 – 20:45 20:45 – 21:00 21:00 – 21:15 21:15 – 21:30

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

47

MONDAY

Poster Session and Guided Poster Walks / Coffee Break

BA.10

Program per Day

MONDAY, SEPT. 7, 2015 OVERVIEW PER TRACK

Keynote Lecture of the Day - KL.C.1 – Innate Immunity 12:45 – 13:45 Chairperson:

Hall A Lorenzo Moretta; Rome, Italy

Intestinal Homeostasis and its Breakdown Fiona Powrie Oxford, United Kingdom

MONDAY

Fiona Powrie is the Director of the Kennedy Institute of Rheumatology and Principal Investigator in the Translational Gastroenterology Unit, University of Oxford. Her research interests include characterisation of the interaction between the intestinal microbiota and the host immune system and how this mutualistic relationship breaks down in inflammatory bowel disease. Her work has identified the functional role of regulatory T cells in intestinal homeostasis and shed light on their development and mechanism of action. She has also shown that both adaptive and innate immune mechanisms contribute to intestinal inflammation and identified the IL-23 pathway as a pivotal player in the pathogenesis of chronic intestinal inflammation. Her current work seeks to translate findings from model systems into the clinic in inflammatory bowel disease patients. Fiona Powrie received the Ita Askonas Award from the European Federation of Immunological Societies for her contribution to immunology in Europe and the Louis Jeantet Prize for Medicine 2012. She was elected a Fellow of the Royal Society in 2011, EMBO in 2013 and the Academy of Medical Sciences in 2014.

OVERVIEW PER TRACK TRACK A – ADAPTIVE IMMUNITY

TRACK C – INNATE IMMUNITY

Symposia S.A.01 Protection by CD8 T Cells S.A.02 Th17 Cells in Human Health and Disease

Symposia S.C.01 Mucosal Immunity S.C.02 Mediators of Inflammation

Bright Sparks Workshop BS.A.1 Bright Sparks Adaptive Immunity

Bright Sparks Workshop BS.C.1 Bright Sparks - Breakthroughs in Innate Immunity

Workshops WS.A.01 WS.A.02 WS.A.03 WS.A.04 WS.A.05

Workshops WS.C.01 WS.C.02 WS.C.03 WS.C.04 WS.C.05 WS.C.06

Molecular & Cellular Control of CD8+ T Cells - Part 1 Germinal Centers: Genetic and Transcriptional Control Molecular and Cellular Control of T Helper Cell Subsets Lymphocyte subsets (part 1) Extrinsic Factors in the Control of B Cells

TRACK B – DISEASES

Leukocyte Trafficking Innate Sensors Myeloid Suppressor Cells Dendritic Cells & Macrophages NK and NKT Cell Activation and Mechanisms Innate Cell Signaling

TRACK D – DISEASE INTERVENTION

Symposia S.B.01 Chronic Inflammation S.B.02 Allergy and Asthma

Symposia S.D.01 Vaccines S.D.02 Immunological Tolerance in Organ Transplantation

Bright Sparks Workshop BS.B.1 Bright Sparks - Insights in Immunological Disease Mechanisms

Bright Sparks Workshop BS.D.1 Bright Sparks – Immunotherapy

Workshops WS.B.01 Generation of Allergen Specific Immune Responses WS.B.02 Control of Inflammation in Autoimmune Diseases WS.B.03 Clinics, Pathophysiology and Genetics of Primary Immunodeficiency Diseases WS.B.04 Lymphocyte Targeting Immune Escape by Tumors WS.B.05 Local Tissue Alteration in Autoimmunity

48

Workshops WS.D.01 WS.D.02 WS.D.03 WS.D.04

Immunosuppresive Therapies and Immunomodulation Drug Immunogenicity and Biomarkers of Efficacy Immune Dissection of Anti-Viral Vaccines Preventive & Therapeutic Approaches

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

MONDAY, SEPT. 7, 2015 Track A TRACK A

BS.A.1.6

The discovery of intra‑sensory signalling in human T lymphocytes Alessio Lanna, A. Akbar; London, United Kingdom

Symposia Workshops Protection by CD8 T Cells

Hall A 08:30 -09:45

nnWS.A.01

Chairpersons: Vincenco Barnaba; Rome, Italy Dietmar Zehn; Lausanne, Switzerland Disparate individual CD8 T cell fates determine robust immune protection Dirk H. Busch; Munich, Germany

S.A.01.2

What T cells see on human cancer Ton N. Schumacher; Amsterdam, Netherlands

S.A.01.3

The impact of macroautophagy on CD8 T cell‑mediated antiviral immunity Matthew Albert; Paris, France

Th17 Cells in Human Health and Disease

Hall A 15:45 – 17:00

Chairpersons: Michael Lohoff; Marburg, Germany Maha Ayyoub; Villejuif, France High‑salt diet and Th17 responses David Hafler; New Haven, United States

S.A.02.2

Pathogen‑driven Th17 cells Federica Sallusto; Bellinzona, Switzerland

S.A.02.3

Regulation of IL‑17 producing T cells in human inflammatory disease Leonie S. Taams; London, United Kingdom

Bright Sparks - Adaptive Immunity

Hall F1

17:45 – 19:00 Chairpersons: Rita Carsetti; Rome, Italy Ari Waisman; Mainz, Germany

BS.A.1.2

BS.A.1.3

WS.A.01.1 A dominant role for Suv39h1 in heterochromatin organization and gene expression programs of short‑lived effector CD8+ T cells Luigia Pace, J. Quivy, C. Goudot, E. Zueva, M. San Roman, M. Maurin, G. Almouzni, S. Amigorena; Paris, France WS.A.01.2 CD8 T cell exhaustion is regulated by Dnmt3a mediated de novo DNA methylation programming Benjamin A. Youngblood, S. Hale, E. Ahn, H. Ghoniem, H. Abdelsamed, S. Im, R. Ahmed; Memphis, United States

WS.A.01.4 Tuning the functional avidity of virus‑specific CD8+ T cells Jovana Cupovic, L. Staerck, V. Nindl, T. Luzyanina, W. Uckert, G. Bocharov, B. Ludewig; St. Gallen, Switzerland

Bright Sparks Workshop

BS.A.1.1

Chairpersons: Yvonne Samstag; Heidelberg, Germany Matthew Albert; Paris, France

WS.A.01.3 T cell specific deletion of STAT1 mediates a protective effect against Listeria monocytogenes infection Roland Tschismarov, M. Aichinger, P. Shukla, C. Vogl, M. Müller, T. Decker; Vienna, Austria

S.A.02.1

nnBS.A.1

Hall F2 11:15 – 12:30

S.A.01.1

nnS.A.02

Molecular & Cellular Control of CD8+ T Cells - Part 1

T cell lipid peroxidation induces ferroptosis and prevents immunity to infection Mai Matsushita, S.B. Freigang, C. Schneider, M. Conrad, G.W. Bornkamm, M. Kopf; Zurich, Switzerland Impact of a gain‑of‑function mutation of CXCR4 on the germinal centre reaction and humoral immunity V. Biajoux, J. Natt, C. Freitas, A. Sacquin, P. Hémon, F. Gaudin, N. Fazilleau, Marion Espeli, K. Balabanian; Clamart, France Liver‑resident regulatory T cells Ann‑Cathrin Hofer, A. Menevse, A. Schnell, M. Delacher, D. Richards, A. Breiling, P. Angel, M. Essers, U. Klingmüller, M. Feuerer; Heidelberg, Germany

WS.A.01.5 Human CD8+ lung resident memory T‑cells: different populations with unique identities exhibit a controlled state of alert Pleun Hombrink, R.A. Backer, B. Piet, D. Amsen, P.D. Moerland, R.A. van Lier; Amsterdam, Netherlands WS.A.01.6 Novel targets of CTLA‑4‑mediated signaling in differentiating CD8+ T lymphocytes Holger Lingel, J. Wissing, A. Arra, F. Klawonn, M. Pierau, L. Jänsch, M. Brunner‑Weinzierl; Magdeburg, Germany

nnWS.A.02

Germinal Centers: Genetic and Transcriptional Control

Hall M

11:15 – 12:30 Chairpersons: Marta Rizzi; Freiburg, Germany Thomas Grundström; Umea, Sweden WS.A.02.1 Regulation of immunoglobulin diversification by checkpoint signalling S. Frankenberger, K. Davari, K. Braunschmidt, K. Böttcher, Berit Jungnickel; Jena, Germany

BS.A.1.4

miR‑148a controls plasma cell differentiation and survival Katharina Pracht, J. Schmid, J. Côrte‑Real, P. Daum, M. Porstner, J. Wittmann, H. Jäck; Erlangen, Germany

WS.A.02.2 Mediator facilitates transcriptional activation and dynamic long‑range contacts at the IgH locus during class switch recombination Anne‑Sophie Thomas‑Claudepierre, E. Schiavo, P.P. Rocha, R. Raviram, L. Gaudot, V. Heyer, J.K. Reddy, T. Borggrefe, J.A. Skok, B. Reina‑San‑Martin; Illkirch, France

BS.A.1.5

Role of the TCR in the development and function of antigen‑specific Tregs Ellen Hilgenberg, E. Kieback, U. Stervbo, V. Lampropoulou, W. Uckert, S. Fillatreau; Berlin, Germany

WS.A.02.3 Regulated localisation of a mutagenic protein complex at the Igh locus during antibody diversification J. Hauser, C. Grundström, R. Kumar, A. Kumar, T. Ahmed, Thomas Grundström; Umeå, Sweden

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

49

MONDAY

nnS.A.01

Program per Day

MONDAY, SEPT. 7, 2015 Track A WS.A.02.4 Ig genes somatic mutation is spatially controlled by IgH Eµ‑matrix attachment regions Sandrine Le Noir, M. Marquet, A. Garot, S. Bender, O. Martin, P. Rouaud, C. Carrion, J. Aldigier, Y. Denizot, M. Cogné, C. Francastel, E. Pinaud; Limoges, France WS.A.02.5 The role of KLF2 and KLF4 in generation, homing and survival of plasma cells in vitro and in vivo A. Wallrapp, R. Winkelmann, H. Jäck, Wolfgang Schuh; Erlangen, Germany

WS.A.04.4 Myeloid derived suppressor cells inhibit cytotoxic T cell immune responses during acute retroviral infection. Malgorzata Drabczyk, T. Werner, U. Dittmer, G. Zelinskyy; Essen, Germany

WS.A.02.6 The ontogeny of human IgE‑expressing B cells and plasma cells Faruk Ramdani, H. Bowen, N. Upton, B. Sutton, D. Fear, H. Gould; London, United Kingdom

WS.A.04.5 Thalidomide analogs implicate a novel pathway of immune regulation P.K. Epling‑Burnette, M.S. Beatty, Rebecca L. Swearingen; Tampa, United States

nnWS.A.03

Molecular and Cellular Control of T Helper Cell Subsets

Hall G 17:45 – 19:00

MONDAY

WS.A.04.3 Regulation of virus‑specific CD8 T cell responses by galectin‑3 Sharvan Sehrawat, H. Ploegh, G. Fink; Mohali Punjab, India

Chairpersons: Jochen Huehn; Braunschweig, Germany Lucy S. Walker; London, United Kingdom WS.A.03.1 Foxo1 is a T‑cell intrinsic inhibitor of the RORgt‑Th17 program Alexandra Lainé, B. Martin, M. Luka, L. Mir, C. Auffray, B. Lucas, G. Bismuth, C. Charvet; Paris, France WS.A.03.2 Role of CD43 in mediating T helper type 17 cell recruitment in inflammation and autoimmunity. Francisco E. Velázquez, A. Grodecki, A. Salvador, A. Knapp, T. Nevers, P. Alcaide; Boston, United States WS.A.03.3 Klf4 expression in conventional dendritic cells is required for T helper 2 cell responses R. Tussiwand, Bart Everts, G.E. Grajales‑Reyes, E.J. Pearce, K.M. Murphy; Basel, Switzerland WS.A.03.4 RNA‑binding protein HuR regulates CD4+ Th2 differentiation and IL‑2 homeostasis and is required for allergic airway inflammation Ulus Atasoy, P. Techasintana, J. Magee, M. Gubin, J. Glascock; Columbia, United States WS.A.03.5 Liver sinusoidal endothelial cells induce immunosuppressive IL‑10‑producing Th1 cells via the Notch pathway Katrin Neumann, C. Rudolph, C. Neumann, M. Janke, D. Amsen, A. Scheffold; Hamburg, Germany WS.A.03.6 The activating receptor NKG2D regulates IL‑10 expression in Th1 cells Marina Babic Cac, Q. Hammer, B. Polic, A. Radbruch, C. Romagnani; Berlin, Germany

nnWS.A.04

Lymphocyte Subsets - Part 1

Hall M 17:45 – 19:00

Chairpersons: Sylvain Cardinaud; Creteil, France Guy Gorochov; Paris, France WS.A.04.1 Functional characterization of different IgG glycosylation variants Daniela Kao, F. Nimmerjahn; Erlangen, Germany

WS.A.04.6 HIV‑1 antisense protein (ASP) is a novel CD8+ T cell target Anne Bet, E. Maze, A. Bansal, S. Graff‑Dubois, I. Theodorou, J. Mesnard, A. Moris, P. Goepfert, S. Cardinaud; Paris, France

nnWS.A.05

Extrinsic Factors in the Control of B Cells

Hall N 17:45 – 19:00

Chairpersons: Marta E. Alarcon‑Riquelme; Granada, Spain Lars Nitschke; Erlangen, Germany WS.A.05.1 BANK1 controls TLR7 signaling in B cells Y. Wu, R. Kumar, I. Georg, R. Iida, H. Bagavant, M. Morell‑Hita, Marta E. Alarcon‑Riquelme; Granada, Spain WS.A.05.2 Bacterial suspension activates B cell differentiation and IL‑10 production via Toll‑Like Receptor‑2 recognition Alberto Salazar, A. Castillo‑Albarran, J. Nieto, J. Galicia‑Carreon, M.C. Jimenez‑Martinez; Mexico City, Mexico WS.A.05.3 Regulation of B cell immunity by interferons Barbara C. Mindt, C.U. Dürr, J.H. Fritz; Montreal, Canada WS.A.05.4 Optimal T cell activation and B cell antibody responses in vivo require the interaction between LFA‑1 and kindlin‑3 V.L. Morrison, Liisa M. Uotila, M. Llort Asens, T. Savinko, S.C. Fagerholm; Helsinki, Finland WS.A.05.5 TLR4‑ and IFNγR‑signaling drive hematopoietic stem cell expansion and common lymphoid progenitor depletion in a model of chronic endotoxemia A. Liu, Y. Wang, N. Scharping, Y. Ding, I. Baez, K. Payne, Lisa Borghesi; Pittsburgh, United States WS.A.05.6 Impact of intestinal immune induction on compartmentalized IgA production in submandibular/ sublingual salivary glands Per Brandtzaeg, A. Aase, H. Sommerfelt, M. Bolstad, R.J. Cox, N. Langeland, A.B. Guttormsen, H. Steinsland, S. Skrede, L.B. Petersen; Oslo, Norway

WS.A.04.2 Cbl‑interacting protein of 85 kDa (CIN85) controls B cell activation by multimerization of intracellular signaling proteins Julius Kühn, S. Pirkuliyeva, L. Wong, S. Becker, C. Griesinger, J. Wienands; Göttingen, Germany

50

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

MONDAY, SEPT. 7, 2015 Track B TRACK B

BS.B.1.5

Exostosin‑like glycosyl transferase 3 (EXTL3) gene mutation causes a novel form of immuno‑osseous dysplasia and unveils a critical role of heparan sulfate in thymopoiesis Stefano Volpi, D. Likun, E. Van Rooijen, A. Hayashaida, k. Felgentreff, K. Capuder, A. Ohno, M. Di Rocco, S. Giliani, E. Hagedorn, P. Poliani, L. Imberti, K. Dobbs, F. Poulain, P. Park, L. Zon, A. Superti‑Furga, L. Notarangelo; Boston, United States

BS.B.1.6

Neutrophils regulate Th2 inflammation by controlling monocyte and dendritic cell development in a murine model of allergic airway disease Dhiren F. Patel, S. Akthar, T. Peiró, S.A. Walker, L.G. Gregory, C.M. Lloyd, R.J. Snelgrove; London, United Kingdom

Symposia Chronic Inflammation

Hall E 08:30 – 09:45

Chairpersons: Anna Erdei; Budapest, Hungary Hans Lassmann; Vienna, Austria S.B.01.1

The many faces of multiple sclerosis Hans Lassmann; Vienna, Austria

S.B.01.2

Chronic gut inflammation Nadine Cerf‑Bensussan; Paris, France

S.B.01.3

Postranslational modifications of autoantigens Lars Klareskog; Stockholm, Sweden

nnS.B.02

Allergy and Asthma

Workshops Hall E

15:45 – 17:00 Chairpersons: Peter Korosec; Golnik, Slovenia Revaz Sepiashvili; Moscow, Russian Federation S.B.02.1

Environmental factors for the development of the allergic immune response early in life Erika von Mutius; Munich, Germany

S.B.02.2

How viruses trigger asthma Peter Openshaw; London, United Kingdom

S.B.02.3

Novel allergy vaccines Rudolf Valenta; Vienna, Austria

Bright Sparks Workshop nnBS.B.1

Bright Sparks - Insights in Immunological Disease Mechanisms Hall F1 11:15 – 12:30

Chairpersons: Georges Coukos; Lausanne, Switzerland Reinhold Schmidt; Hannover, Germany BS.B.1.1

Apics deficiency reveals a role for lncRNA in dendritic cell function and autoimmune disease Edward P. Chu, M.P. Ashton, C.M. Elso, L. Mackin, S.L. Ford, N.L. Payne, M.A. Alsayb, H.E. Thomas, S.I. Mannering, T.W. Kay, A.T. Papenfuss, R.A. Kitching, C.C. Bernard, G. Morahan, K. Shortman, M. O’Keeffe, T.C. Brodnicki; Fitzroy, Victoria, Australia

BS.B.1.2

Accumulation of tolerogenic human 6‑sulfo LacNAc+ dendritic cells in renal cell carcinoma is associated with poor prognosis Rebekka Wehner, M. Toma, A. Kloß, S. Füssel, B. Seliger, E. Noessner, K. Schäkel, M. Wirth, G. Baretton, M. Schmitz; Dresden University of Technology, Dresden, Germany

BS.B.1.3

The DH/PH domain of BCR‑ABL mediates iNKT cells immunosubversion in chronic myeloid leukemia by downregulating CD1d cell‑surface expression in myeloid dendritic cells Sara BASBOUS, A. Levescot, N. Piccirilli, C. Giraud, L. Roy, F. Guilhot, N. Bourmeyster, A. Herbelin, J. Gombert; Poitiers, France

BS.B.1.4

Concomitant Ezh1/2 inactivation, but not Ezh2 alone, impairs growth of c‑MYC driven B‑cell lymphomas Valentina Petrocelli, G. Varano, J. Jin, S. Casola; Milan, Italy

www.eci-vienna2015.org

nnWS.B.01

Generation of Allergen Specific Immune Responses

Hall G 11:15 – 12:30

Chairpersons: Barbara Bohle; Vienna, Austria Philippe Moingeon; Antony, France WS.B.01.1 Massively expanded Foxp3+ regulatory T cells directed against airborne antigens display non‑overlapping target specificity with Th2 cells Petra Bacher, O. Kniemeyer, A. Schönbrunn, N. Koester‑Eiserfunke, B. Sawitzki, M. Assenmacher, E. Rietschel, A. Steinbach, O. Cornely, C. Schwarz, M. Worm, A. Brakhage, A. Thiel, A. Scheffold; Berlin, Germany WS.B.01.2 Tolerogenic dendritic cells generated by activin‑A‑induced regulatory T cells protect against allergic asthma through the instruction of Foxp3+ regulatory T cells Maria Semitekolou, I. Morianos, T. Sparwasser, G. Xanthou; Athens, Greece WS.B.01.3 T cell‑derived exosomes suppress casein‑induced delayed‑type hypersensitivity reaction in mice Krzysztof Bryniarski, M. Santocki, K. Nazimek, M. Ptak, W. Ptak; Krakow, Poland WS.B.01.4 Perinatal exposure to galactooligosaccharides/inulin prebiotics prevent food allergy by protecting intestine and promoting tolerance. Laure Castan, G. Bouchaud, J. Chabauty, P. Aubert, M. Neunlist, A. Magnan, M. Bodinier; Nantes, France WS.B.01.5 The effect of early postnatal colonisation of newborns by probiotic vaccine Colinfant New Born on allergy incidence and Tregs Jiri Hrdy, O. Novotna, K. Vlachynska, L. Prokesova; Prague, Czech Republic WS.B.01.6 The environment alters allergenicity of ragweed pollen Shu‑Hua Liu, M. Debiasi, C.B. Anea, G. Karrer, A. Bellaire, P. Chaturvedi, W. Weckwerth, M.M. Epstein; Vienna, Austria

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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MONDAY

nnS.B.01

Program per Day

MONDAY, SEPT. 7, 2015 Track B nnWS.B.02

Control of Inflammation in Autoimmune Diseases

Hall K 11:15 – 12:30

Chairpersons: Clemens Scheinecker; Vienna, Austria Vivianne Malmström; Stockholm, Sweden

MONDAY

WS.B.02.1 Transient ablation of Foxp3+ regulatory T cells unleashes overt diabetes in the NOD model of human type 1 diabetes Deepika Watts, M. Janßen, A. Hommel, T. Sparwasser, S. Schallenberg, E. Bonifacio, K. Kretschmer; Dresden, Germany WS.B.02.2 Novel B cell‑derived peptide regulation of homeostatic T‑cell trafficking is subverted in rheumatoid arthritis. Helen M. McGettrick, M. Chimen, A. Martin, F. Barone, L. Walker, A. Filer, K. Raza, C.D. Buckley, P. Narendran, G. Rainger; Birmingham, United Kingdom WS.B.02.3 Cutaneous 4‑1BB/4‑1BBL signaling is crucially involved in the induction of itch and inflammation Kristian Holz, V. Kupas, C. Baumann, L. Klenner, N. Sucker, M. Schneeweiß, M. Maurer, S. Beissert, T. Luger, S. Ständer, K. Loser; Muenster, Germany WS.B.02.4 Regulatory CD19+CD24hiCD38hi B cells are decreased in patients with atherosclerosis and have impaired interleukin‑10 production Ingrid E. Dumitriu, P. Baruah, S. Dinkla, J.C. Kaski; London, United Kingdom WS.B.02.5 Relevance of the aryl hydrocarbon receptor in the disease progression of murine and human systemic lupus erythematosus Christoph Baumann, E. Hesse, K. Holz, L. Klenner, N. Sucker, M. Schneeweiß, A. Jacobi, C. Esser, T.A. Luger, K. Loser; Münster, Germany WS.B.02.6 Multiple sclerosis‑associated genetic variants of CD226 impair regulatory T cell function Anne Willing, M. Piédavent‑Salomon, J.B. Engler, K. Steinbach, S. Bauer, B. Eggert, F. Ufer, N. Kursawe, S. Wehrmann, J. Jäger, S. Reinhardt, M.A. Friese; Hamburg, Germany

nnWS.B.03

Clinics, Pathophysiology and Genetics of Primary Immunodeficiency Diseases Hall N 11:15 – 12:30

Chairpersons: Ellen Renner; Munich, Germany Mirjam van der Burg; Rotterdam, Netherlands WS.B.03.1 Cytidine triphosphate synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation Emmanuel Martin, N. Palmic, S. Sanquer, C. Lenoir, F. Hauck, C. Mongellaz, S. Fabrega, P. Nitschké, C. Picard, A. Fischer, P. Arkwright, S. Latour; Paris, France WS.B.03.2 A novel primary immunodeficiency disorder with multiple defects of the lymphoid system caused by biallelic loss‑of‑function mutation in the NF‑κB inducing kinase NIK Katharina L. Willmann, S. Klaver, F. Doğu, E. Santos‑Valente, W. Garncarz, I. Bilic, E. Mace, E. Salzer, C. Domínguez Conde, H. Sic, P. Májek, P.P. Banerjee, G.I. Vladimer, S. Haskoloğlu, M.G. Bolkent, A. Küpesiz, A. Condino‑Neto, J. Colinge, G. Superti‑Furga, W.F. Pickl, M.C. van Zelm, H. Eibel, J.S. Orange, A. Ikincioğulları, K. Boztuğ; Vienna, Austria

52

WS.B.03.3 Human DOCK2 mutations underlie a novel, pleiotropic immunodeficiency syndrome with early onset, invasive infections Cecilia Domínguez Conde*, K. Dobbs*, S. Zhang*, S. Parolini*, M. Audry, J. Chou, E. Haapaniemi, S. Keles, I. Bilic, M.J. Massaad, S. Rounioja, N.K. Serwas, C. Bock, T. Chatila, A. Comeau, R.S. Geha, L. Abel, R.H. Buckley, A. Ikincioğullari, W. Al‑Herz, M. Helminen, F. Doğu, J. Casanova, L.D. Notarangelo, K. Boztug; Vienna, Austria WS.B.03.4 Different STAT1 gain‑of‑function mutations give rise to different clinical presentations: from isolated chronic mucocutaneos candidiasis to a complex combined immunodeficiency Laura Martinez‑Martinez, M. Lozano‑Rabella, M. Rubiales, M. Barnadas, I. Badell, C. Rodriguez‑Gallego, O. de la Calle‑Martin; Barcelona, Spain WS.B.03.5 Investigation of ASXL1 mutations in GATA2 deficient individuals Rachel E. Dickinson, Y. Li, S. Pagan, V. Bigley, M. Collin; Newcastle upon Tyne, United Kingdom WS.B.03.6 CD21 and CD19 deficiency: two defects in the same complex leading to different disease modalities Marjolein W. Wentink, L.J. Annechien, M.C. van Zelm, E. Simons, J.J. van Dongen, H. IJspeert, E.H. Schölvinck, M. van der Burg; Rotterdam, Netherlands

nnWS.B.04

Lymphocyte Targeting Immune Escape by Tumors

Hall F2 17:45 – 19:00

Chairpersons: Ignacio J. Melero; Pamplona, Spain Mirjam H.M. Heemskerk; Utrecht, Netherlands WS.B.04.1 Tumor‑associated B cells induce therapy resistance of melanoma Stephan N. Wagner, R. Somasundaram, G. Zhang, M. Perego, M. Fukunaga‑Kalabris, K. Garg, M. Maurer, M. Herlyn; Vienna, Austria WS.B.04.2 Intra‑tumor CD4+CD8+ double positive T cells: a new target for IL‑9 Tiphaine Parrot, M. Allard, R. Oger, H. Benlalam, D. Raingeard de la Blétière, L. Pressier, J. Desfrançois, A. Khammari, B. Dréno, N. Labarrière, Y. Delneste, P. Guardiola, N. Gervois; Nantes, France WS.B.04.3 The impact of secondary iTreg clones in the TCR repertoire of tumor patients. Maria Xydia, E. Ruggiero, S. Mastitskaya, N. Halama, M. Schmidt, C. von Kalle, P. Beckhove; Heidelberg, Germany WS.B.04.4 Multiple co‑inhibitory pathways contribute to dysfunctionality of intra‑tumoral T cells in liver cancer Guoying Zhou, D. Sprengers, P.P. Boor, W. Polak, J. de Jonge, J.N. IJzermans, D. Grünhagen, C. Verhoef, M. Doukas, M.J. Bruno, J. Kwekkeboom; Rotterdam, Netherlands WS.B.04.5 Dissecting early mechanisms of melanoma cell resistance to cytotoxic T lymphocyte attack Roxana Khazen, S. Muller, M. Puisségur, S. Valitutti; Toulouse, France

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

MONDAY, SEPT. 7, 2015 Track C

nnWS.B.05

Local Tissue Alteration in Autoimmunity

Hall K

TRACK C Symposia nnS.C.01

Mucosal Immunity

Hall A 11:15 – 12:30

Chairpersons: Andrea Cerutti; Barcelona, Spain Per Brandtzaeg; Oslo, Norway S.C.01.1

Microbiota and gut immunity Andrew J. MacPherson; Bern, Switzerland

Chairpersons: Thomas Weichhart; Vienna, Austria Albert Zlotnik; Irvine, United States

S.C.01.2

Adaptive humoral immunity repertoire Oliver Pabst; Aachen, Germany

WS.B.05.1 Islet‑intrinsic susceptibility to apoptosis and senescence in non‑obese diabetic mice Susann Schonefeldt, L. Tian, J. Dooley, E.J. Carr, J.E. Garcia‑Perez, J. Vandenbussche, J. Allemeersch, D. Franckaert, V. Delghingaro‑Augusto, K. Gevaert, P.A. Jeggo, C. Mathieu, A.M. Jetten, M.A. Linterman, C.C. Goodnow, C.J. Nolan, S. Lesage, S.M. Schlenner, A. Liston; Leuven, Belgium

S.C.01.3

Mucosal dendritic cells in immunity and inflammation Maria Rescigno; Milan, Italy

WS.B.05.2 S100A8 and S100A9 proteins are expressed but dispensable in the pathogenesis of experimental epidermolysis bullosa acquisita and bullous pemphigoid Reza Akbarzadeh, X. Yu, T. Vogl, R.J. Ludwig, D. Zillikens, F. Petersen; Borstel, Germany

S.C.02.1

Cytokine regulation of humoral innate immunity Alberto Mantovani; Rozzano, Italy

S.C.02.2

TIR domains in mediation of MyD88‑dependent signaling in innate immunity Roman Jerala, M. Avbelj, M. Benčina, O. Fekonja, G. Panter; Ljubljana, Slovenia

S.C.02.3

Complement Claudia Kemper; London, United Kingdom

17:45 – 19:00

WS.B.05.3 Inflammasome activity is essential for one kidney/ deoxycorticosterone acetate/salt‑induced hypertension in mice Shalini M. Krishnan, J.K. Dowling, Y.H. Ling, H. Diep, C.T. Chan, D. Ferens, M.K. Kett, A. Pinar, C.S. Samuel, A. Vinh, T. Arumugam, T.D. Hewitson, B.K. Kemp‑Harper, A.B. Robertson, M. Cooper, E. Latz, A. Mansell, C.G. Sobey, G.R. Drummond; Clayton, Australia WS.B.05.4 The chemokine platelet factor‑4 variant (PF‑4var)/ CXCL4L1 antagonizes vascular endothelial growth factor functions and inhibits diabetes‑induced blood‑retinal barrier breakdown Sofie Struyf, G. Mohammad, M.I. Nawaz, K. Van Raemdonck, G. De Hertogh, J. Van Damme, A.M. El‑Asrar; Leuven, Belgium WS.B.05.5 Identification of CXCR8, the new chemokine receptor for the critical macrophage chemotactic factor CXCL17 Amanda Burkhardt, J. Maravillas‑Montero, P. Hevezi, C. Carnevale, M.J. Smit, A. Zlotnik; Irvine, United States

nnS.C.02

Hall A 17:45 – 19:00

Chairpersons: Thomas Decker; Vienna, Austria Christian Bogdan; Erlangen, Germany

Bright Sparks Workshop nnBS.C.1

Bright Sparks Breakthroughs in Innate Immunity

Hall F1

08:30 – 09:45 Chairpersons: Luke O’Neill; Dublin, Ireland Angela Santoni; Rome, Italy BS.C.1.1

Tick salivary Sialostatin L represses the initiation of immune responses by targeting IRF4‑dependent transcription in murine mast cells Till‑Julius Brühl, M. Klein, S. Reuter, T. Bohn, N. Stergiou, S. Dietzen, A. Ulges, M. Hoffmann, V. Staudt, T. Hain, M. Kotsyfakis, E. Schmitt, T. Bopp; Mainz, Germany

BS.C.1.2

Identification of subset‑specific dendritic cell progenitors reveals early lineage‑priming in the bone marrow Andreas Schlitzer, S. V, J. Chen, H. Rizal Bin Sumatoh, J. Schreuder, J. Lum, B. Malleret, S. Zhang, A. Larbi, F. Zolezzi, L. Renia, M. Poidinger, S. Naik, E. Newell, P. Robson, F. Ginhoux; Bonn, Germany

BS.C.1.3

PTX3 is an extrinsic oncosuppressor regulating complement‑dependent inflammation in cancer Eduardo Bonavita, E. Magrini, S. Gentile, M. Rubino, V. Maina, R. Papait, P. Kunderfranco, C. Greco, F. Feruglio, M. Molgora, I. Laface, S. Tartari, A. Doni, F. Pasqualini, E. Barbati, M.R. Galdiero, G. Basso, M. Nebuloni, M. Roncalli, P. Colombo, L. Laghi, J.D. Lambris, S. Jaillon, C. Garlanda, A. Mantovani; Rozzano, Italy

WS.B.05.6 Effect of maternal AQP4‑IgG antibody transfer in neuromyelitis optica pregnancies Simone Mader, L. Brimberg, J.M. Crawford, A. Bonnin, J.L. Bennett, P. Huerta, B.T. Volpe, B. Diamond; Manhasset, United States

www.eci-vienna2015.org

Mediators of Inflammation

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

53

MONDAY

WS.B.04.6 Hypoxia‑induced soluble CD137 in malignant cells blocks CD137L‑costimulation as an immune escape mechanism Sara Labiano, A. Palazon, E. Bolaños, A. Azpilikueta, A. Morales‑Kastresana, A.R. Sanchez‑Paulete, J.I. Quetglas, J.L. Perez‑Gracia, A. Gurpide, M. Rodriguez‑Ruiz, M.A. Aznar, M. Jure‑Kunkel, P. Berraondo, I. Melero; Pamplona, Spain

Program per Day

MONDAY, SEPT. 7, 2015 Track C BS.C.1.4

Humanized mouse model of mast cell‑mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis Laurie L. Kenney, P.J. Bryce, R. Falahati, C. Bebbington, N. Tomasevic, L.D. Shultz, D.L. Greiner, M.A. Brehm; Worcester, United States

BS.C.1.5

The role of Interleukin‑27 in regulation of type 2 innate lymphoid cells Tamar Mchedlidze, M. Kindermann, D. Voehringer, M. Neurath, S. Wirtz; Erlangen, Germany

BS.C.1.6

Regulation of MHC class I endocytosis by the macroautophagy machinery Monica Loi, M. Gannagé, A. Lippmann, A. Becker, J. Dengjel, C. Münz; Zurich, Switzerland

MONDAY

Workshops nnWS.C.01

Leukocyte Trafficking

Hall G 08:30 – 09:45

Chairpersons: Ronen Alon; Rehovot, Israel Johannes Huppa; Vienna, Austria WS.C.01.1 Novel regulation of dendritic cell trafficking to lymph nodes by the hyaluronan receptor LYVE‑1 Louise A. Johnson, W. Lawrance, Y. Roshorm, T. Hanke, S. Banerji, D.G. Jackson; Oxford, United Kingdom WS.C.01.2 CXCR8 is the receptor of the mucosal chemokine CXCL17 José L. Maravillas‑Montero, A.M. Burkhardt, P.A. Hevezi, C. Carnevale, M.J. Smit, A. Zlotnik; México DF, Mexico WS.C.01.3 Platelets and neutrophils require different kindlin‑3 copy numbers to control integrin‑mediated functions in vivo Sarah Klapproth, F. Moretti, M. Zeiler, R. Ruppert, U. Breithaupt, R. Haas, M. Mann, M. Sperandio, R. Fässler, M. Moser; Martinsried, Germany WS.C.01.4 The positively charged glycosaminoglycan‑binding CXCL9‑derived peptide, CXCL9(74‑103), inhibits CXCL8‑induced neutrophil extravasation and monosodium urate crystal‑induced gout in mice. Anneleen Mortier, V. Vanheule, R. Janssens, D. Boff, N. Berghmans, I. Ronsse, F.A. Amaral, M.M. Teixeira, J. Van Damme, P. Proost; Leuven, Belgium WS.C.01.5 The endothelial protein PLVAP in lymphatics controls the entry of leukocytes into lymph nodes Pia Rantakari, N. Jäppinen, K. Auvinen, M. Kapraali, M. Miyasaka, S. Jalkanen, M. Salmi; Turku, Finland WS.C.01.6 Role of CD99 in leukocyte transendothelial migration Debashree Goswami, D. Jing, S. Yan, K. Schaefer, M. Araki, K. Araki, K. Yamamura, D. Vestweber; Muenster, Germany

nnWS.C.02

Innate Sensors

Hall K 08:30 – 09:45

Chairpersons: Sergei A. Nedospasov; Moscow, Russian Federation Ihsan Gursel; Ankara, Turkey WS.C.02.1 AIM2 suppresses colon tumorigenesis by interfering with DNA‑PK‑dependent Akt activation Justin E. Wilson, A. Petrucelli, L. Chen, A. Koblanski, A. Truax, Y. Wang, M. Muehlbauer, B. Davis, J.P. Ting; Chapel Hill, United States

54

WS.C.02.2 Identification of the lipid‑modifying enzyme SMPDL3B as novel regulator of innate immune responses Leonhard X. Heinz, C.L. Baumann, M.S. Köberlin, B. Snijder, M. Bruckner, R. Gawish, O. Sharif, R.K. Kandasamy, J. Colinges, K.L. Bennett, A. Fauster, G. Shui, M.R. Wenk, S. Knapp, G. Superti‑Furga; Vienna, Austria WS.C.02.3 Novel mouse models reveal in vivo functions of the NAIP/NLRC4 inflammasomes in non‑hematopoietic cells Isabella Rauch, C. Kang, J. von Moltke, L.E. Sanman, M. Bogyo; Berkeley, United States WS.C.02.4 Fungal recognition mediated by C‑type lectin receptors Dectin‑1 and Dectin‑2 is regulated by E3 ubiquitin ligase Cbl‑b Jian Zhang, Y. Xiao, H. Guo; Columbus, United States WS.C.02.5 SHIP‑1 couples to activated Dectin‑1 selectively adjusting ROS production in response to C. albicans in dendritic cells Carlos Del Fresno Sánchez, N. Blanco‑Menéndez, S.R. Fernandes, E. Calvo, R. Conde‑Garrosa, W.G. Kerr, D. Sancho; Madrid, Spain WS.C.02.6 Complement‑regulated NLRP3 inflammasome activation controls CD4+ Th1 responses Giuseppina Arbore, E. West, A.A. Robertson, A. Klos, T.M. Woodruff, R.C. Coll, L.A. O’Neill, W.J. Leonard, P.N. Monk, M.A. Cooper, H.J. Lachmann, A. Cope, K.D. Mayer‑Barber, C. Kemper; London, United Kingdom

nnWS.C.03

Myeloid Suppressor Cells

Hall M 08:30 – 09:45

Chairpersons: Vincenzo Bronte; Verona, Italy Reinhold Förster; Hannover, Germany WS.C.03.1 Controversial effect of atRA in treatment of Non‑Responders in therapeutic vaccination Bastian Höchst; München, Germany WS.C.03.2 Monocytes polarize in two steps into myeloid‑derived suppressor cells requiring IRF‑1 and mTOR signals E. Ribechini, J. Hutchinson, S. Walter, J. Lucas, U. Schleicher, A. Jordán Garrote, S.J. Potter, N. Müller, H. Raifer, I. Berberich, M. Huber, H. Hermanns, A. Beilhack, M. Lohoff, C. Bogdan, E.K. Geissler, Manfred B. Lutz; Würzburg, Germany WS.C.03.3 Myeloid‑derived suppressor cells contribute to lysosomal acid lipase deficiency‑induced endothelial cell dysfunctions Hong Du, T. Zhao, X. Ding, C. Yan; Indianapolis, United States WS.C.03.4 Generation and function of CCR7‑expressing regulatory macrophages Kai Yu, M. Galla, A. Janssen, R. Förster; Hannover, Germany WS.C.03.5 Establishment of lal‑/‑ myeloid lineage cell line that resembles myeloid‑derived suppressive cells Cong Yan, X. Ding, L. Wu, H. Du; Indianapolis, United States WS.C.03.6 Adipose‑derived mesenchymal stromal cells modulate the lipid metabolism in regulatory macrophage Luciana Souza‑Moreira, V. Cardoso‑Soares, E. Gonzalez‑rey, M. Delgado, P. Bozza; Rio de Janeiro, Brazil

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

MONDAY, SEPT. 7, 2015 Track C Dendritic Cells & Macrophages

Hall N 08:30 – 09:45

Chairpersons: Adelheid Elbe‑Bürger; Vienna, Austria Greta Guarda; Lausanne, Switzerland WS.C.04.1 Human BDCA2+CD123+CD56+ dendritic cells (DCs) related to blastic plasmacytoid dendritic cell neoplasm represent a unique myeloid DC subset H. Yu, P. Zhang, X. Yin, Z. Yin, Q. Shi, Y. Cui, G. Liu, S. Wang, P. Piccaluga, T. Jiang, Liguo Zhang; Beijing, China WS.C.04.2 Anti‑TNF promotes type I interferon‑driven psoriasis‑like skin inflammation C. Conrad, J. Di Domizio, Alessio Mylonas, C. Belkhouja, O. Demaria, A. Lapointe, M. Vernez, A. Navarini, L. French, M. Gilliet; Lausanne, Switzerland WS.C.04.3 Endogenous glucocorticoids suppress dendritic cell‑derived IL‑12 and prevent death in LPS‑induced sepsis Ivana Munitic, C.C. Li, P.R. Mittelstadt, E. Castro, J.D. Ashwell; Rijeka, Croatia WS.C.04.4 Polysialylation of CCR7 controls dendritic cell trafficking by releasing CCL21 from an auto‑inhibited state Eva Kiermaier, C. Moussion, C. Veldkamp, R. Gerardy‑Schahn, L. Williams, G. Chaffee, A. Phillips, F. Freiberger, R. Imre, K. Mechtler, M. Mühlenhoff, B. Volkman, M. Sixt; Klosterneuburg, Austria WS.C.04.5 Kupffer cells regulate the onset of immune response against Listeria monocytogenes infection Chloé Abels, D. Torres, A. Kohler, M. Guilliams, P. De Baetselier, V. Flamand, A. Beschin; Brussels, Belgium

nnWS.C.05

NK and NKT Cell Activation and Mechanisms

Hall F2 15:45 – 17:00

Chairpersons: Rosa Molfetta; Rome, Italy Carsten Watzl; Dortmund, Germany WS.C.05.1 Identification of phenotypically and functionally heterogeneous mouse Mucosal Associated Invariant T cells using MR1 tetramers Hui‑Fern F. Koay, A. Rahimpour, A. Enders, R. Clanchy, S.B. Eckle, B. Meehan, Z. Chen, B. Whittle, L. Liu, D.P. Fairlie, C.C. Goodnow, J. McCluskey, J. Rossjohn, A.P. Uldrich, D.G. Pellicci, D.I. Godfrey; Parkville VIC, Australia WS.C.05.2 Ly49A and NKG2D co‑localise upon synapse formation providing a molecular mechanism for NK cell signal integration David Tomaz, P. Pereira, R. Henriques, N. Guerra, J. Dyson, K. Gould; London, United Kingdom

WS.C.05.5 CXCR6 marks a novel subset of human liver NK cells with a T‑bet(lo)Eomes(hi) transcriptional profile Kerstin A. Stegmann, F. Robertson, C. Pallant, T. Christophides, G. Fusai, B.R. Davidson, L.J. Pallett, D. Peppa, N. Hansi, P. Kennedy, V. Male, C. Dunn, M.K. Maini; London, United Kingdom WS.C.05.6 STAT5‑ the molecular switch from tumor surveillance to tumor promotion Dagmar Gotthardt, E.M. Putz, E. Grundschober, V. Sexl; Vienna, Austria

nnWS.C.06

Innate Cell Signaling

Hall K 15:45 – 17:00

Chairpersons: Birgit Strobl; Vienna, Austria Toby Lawrence; Marseille, France WS.C.06.1 STAT1 isoforms in transcriptional control ‑ distinct traits Matthias Parrini, C. Semper, N. Leitner, C. Lassnig, C. Vogl, S. Wienerroither, T. Decker, M. Müller, B. Strobl; Vienna, Austria WS.C.06.2 Protein tyrosine phosphatase receptor type γ is a JAK phosphatase and negatively regulates leukocyte integrin activation Michela Mirenda, L. Toffali, A. Montresor, G. Scardoni, C. Sorio, C. Laudanna; Verona, Italy WS.C.06.3 The non‑canonical MAPK p38gamma controls inflammatory response of airway epithelial cells and promotes allergic airway inflammation Michael Mihlan, A. Godel, F. Daubeuf, N. Frossard, R. Ricci; Illkirch‑Grafenstaden, France WS.C.06.4 p38‑MK2/3 is the key signaling module for IL‑33‑induced effector functions in BMDCs Christiane Göpfert, F. Weber, T. Kamradt, S. Drube; Jena, Germany WS.C.06.5 A novel Tsc2‑mTORC1‑CDK4 axis controls tissue homeostasis by regulating polarization, proliferation, and metabolism in macrophages Monika Linke, H. Pham, T. Schnöller, A. Miller, M. Schöller, K. Katholnig, M. Hirtl, F. Demel, S. Üstün, A. Preitschopf, B. Niederreiter, S. Blüml, M. Mikula, M. Müller, M. Hengstschläger, A. Haschemi, M. Susani, W. Weckwerth, T. Weichhart; Vienna, Austria WS.C.06.6 Myeloid dendritic cell‑specific mTORC2 deficiency enhances Th1 and Th17 cell responses and inhibits B16 melanoma growth Dalia Raich‑Regue, B.R. Rosborough, K.L. Fabian, W.J. Storkus, A.W. Thomson; Pittsburgh, United States

WS.C.05.3 Modulation of NK cell function by interactions between 2B4 and CD48 in cis and in trans M. Claus, S. Wingert, Carsten Watzl; Dortmund, Germany WS.C.05.4 The TLR 2/6 agonist MALP‑2 mediates increased NK cell cytotoxicity when PGE2 production by monocytes is inhibited by COX‑2 blockade D.M. Tufa, C. Müller, D. Chatterjee, P.F. Mühlradt, R.E. Schmidt, Roland Jacobs; Hannover, Germany

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

55

MONDAY

nnWS.C.04

Program per Day

MONDAY, SEPT. 7, 2015 Track D TRACK D

BS.D.1.5

Analysis of NK cells immune response in Ipilimumab treated Melanoma patients Rossana Tallerico, C.M. Cristiani, M. Capone, G. Madonna, C. Garofalo, E. Staaf, E. Palella, D. Mallardo, R. Sottile, E. Simeone, A.M. Grimaldi, G. Ciliberto, E. Gulletta, F. Colucci, K. Kärre, P.A. Ascierto, E. Carbone; Catanzaro, Italy

BS.D.1.6

PD‑L1 blockade impacts regulatory T‑cells in HIV‑infection in a disease stage dependent manner Cristina Peligero, J. Argilaguet, R. Güerri‑Fernandez, B. Torres, C. Ligero, P. Colomer, M. Plana, H. Knobel, F. García, A. Meyerhans; Barcelona, Spain

Symposia nnS.D.01

Vaccines

Hall E 11:15 – 12:30

MONDAY

Chairpersons: Franz X. Heinz; Vienna, Austria Riitta Lahesmaa; Turku, Finland S.D.01.1

Influenza vaccines for the 21st century Ethan Settembre; Cambridge, United States

S.D.01.2

Protective CD8 T cell immunity to malaria and Ebola Adrian Hill; Oxford, United Kingdom

S.D.01.3

Current and future status of HIV vaccination Brigitte Autran; Paris, France

nnS.D.02

Immunological Tolerance in Organ Transplantation

nnWS.D.01

Hall E

Chairpersons: Thomas Wekerle; Vienna, Austria Eva M Martínez‑Cáceres; Badalona, Spain S.D.02.1

Deciphering the mechanism of operational tolerance in transplantation Sophie Brouard; Nantes, France

S.D.02.2

Regulatory cell therapy for tolerance in organ transplantation Kathryn Wood; Oxford, United Kingdom

S.D.02.3

Transplantation tolerance through mixed chimerism Thomas Wekerle; Vienna, Austria

Bright Sparks Workshop Bright Sparks – Immunotherapy

Hall F1 15:45 – 17:00

Chairpersons: Lucienne Chatenoud; Paris, France Christina Mingari; Genoa, Italy BS.D.1.1

BS.D.1.2

Interleukin‑2/anti‑interleukin‑2 antibody complexes expand T regulatory cells which protect against allergen‑induced airway hyperreactivity Alina Neunkirchner, D. Wojta‑Stremayr, K.G. Schmetterer, L. Mager, V. Reichl, E. Rosloniec, R. Naumann, G. Dekan, B. Jahn‑Schmid, B. Jahn‑Schmid, B. Bohle, W.F. Pickl; Vienna, Austria CD8+CD45RClow T regulatory cells: a promising cell‑based therapy to induce immune tolerance Séverine Bézie, L. Boucault, V. Daguin, I. Anegon, C. Guillonneau; Nantes, France

BS.D.1.3

Flexible antigen‑specific redirection of human regulatory T cells via a novel universal chimeric antigen receptor‑based system Stefanie Koristka, M. Cartellieri, C. Arndt, A. Feldmann, S. Loff, S. Albert, M. Bornhäuser, A. Ehninger, G. Ehninger, M. Bachmann; Dresden, Germany

BS.D.1.4

A germinal center immunomodulator: The CTA1‑DD adjuvant acts on follicular dendritic cells and potentiates follicular T helper cell functions Sophie Schussek, J. Mattsson, K. Schön, N. Lycke; Göteborg, Sweden

56

Immunosuppresive Therapies and Immunomodulation

Hall F2

08:30 – 09:45

17:45 – 19:00

nnBS.D.1

Workshops

Chairpersons: Thomas Kamradt; Jena, Germany Güher Saruhan‑Direskeneli; Istanbul, Turkey WS.D.01.1 Regulatory T cell identifies optimal responders to fingolimod therapy in multiple sclerosis patients Carmen Picon, S. Sainz de la Maza, E. Rodriguez, M. Espiño, A. Bermejo, C. de Andrés, Y. Aladro, J. Alvarez‑Cermeño, L. Villar; Madrid, Spain WS.D.01.2 Generation of MHC class I allospecific regulatory T cells using chimeric antigen receptors to elicit targeted transplant tolerance Dominic Boardman, M. Ibrahim, G. Fruhwirth, R. Lechler, J. Maher, L. Smyth, G. Lombardi; London, United Kingdom WS.D.01.3 Hepatic expression of an allogeneic MHC I molecule induces specific regulatory CD8 T cells and prolongs fully allogeneic graft survival in mice Valentin Le Guen, J. Judor, F. Boeffard, V. Gauttier, N. Ferry, S. Brouard, S. Conchon; Nantes, France WS.D.01.4 The Jak1/3 inhibitor tofacitinib drives human plasmacytoid dendritic cells into apoptosis and inhibits IFN‑alpha production Patrick P. Boor, P.E. de Ruiter, H.J. Metselaar, L.J. van der Laan, J. Kwekkeboom, Gastroenterology and Hepatology, Surgery; Rotterdam, Netherlands WS.D.01.5 17‑phenyl trinor (pt)‑PGE2 counteracts LPS‑induced acute pulmonary inflammation in mice and promotes endothelial barrier function Anna Theiler, V. Konya, I. Lanz, W. Platzer, R. Schuligoi, A. Heinemann; Graz, Austria WS.D.01.6 Selective blockade of the CD28/B7/CTLA4 pathway with monovalent anti‑CD28 antibody versus targeting of B7 with Belatacept, in non‑human primate kidney allograft Nicolas Poirier, S. Ville, J. Hervouet, D. Minault, B. Vanhove, G. Blancho; Nantes, France

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

MONDAY, SEPT. 7, 2015 Track D Drug Immunogenicity and Biomarkers of Efficacy

Hall G 15:45 – 17:00

Chairpersons: Sylvie Bertholet-Girardin; Siena, Italy Anna Fogdell‑Hahn; Stockholm, Sweden WS.D.02.1 Detection of cell sensitization to infliximab in treated patients without anti‑drug antibodies Alessandra Vultaggio, F. Nencini, S. Pratesi, A. Matucci, E. Maggi; Florence, Italy WS.D.02.2 Identification of T cell response to inflliximab peptides in treated patients. Sara Pratesi, F. Nencini, E. Maggi, A. Matucci, A. Vultaggio; Florence, Italy WS.D.02.3 Complement C3 facilitates endocytosis of therapeutic factor VIII by antigen‑presenting cells in hemophilia A Mathieu Ing, J. Rayès, I. Peyron, S. Delignat, C. Vogel, D. Fritzinger, V. Frémeaux‑Bacchi, S. Kaveri, L. Roumenina, S. Lacroix‑Desmazes; Paris, France WS.D.02.4 Why do some PEGylated biotherapeutics induce antibodies against PEG? Christian Lubich, M. Weiller, J. Siekmann, F.M. Horling, M. de la Rosa, F. Scheiflinger, B.M. Reipert; Vienna, Austria WS.D.02.5 T‑cell subsets with T follicular helper features are predictive of late antibody responses F. Spensieri, E. Siena, E. Borgogni, L. Zedda, R. Cantisani, N. Chiappini, D. Rosa, F. Schiavetti, F. Castellino, E. Montomoli, D. Lewis, Sylvie Bertholet, G. del Giudice; Siena, Italy

Immune Dissection of Anti-Viral Vaccines

WS.D.03.6 A vaccine strategy that fully protects against congenital CMV has to include the viral pentameric glycoprotein complex in addition to other neutralizing glycoprotein target antigens but does not require the pp65 T cell target antigen Alistair McGregor, D. Horvat, Y. Choi; College Station, United States

nnWS.D.04

Preventive & Therapeutic Approaches

Hall N 15:45 – 17:00

Chairpersons: Francesca Granucci; Milan, Italy Beatrix Grubeck‑Loebenstein; Innsbruck, Austria WS.D.04.1 Immunogenicity and efficacy of self‑amplifying RNA vaccines expressing multiple conserved Influenza antigens Diletta Magini, S. Buccato, S. Mangiavacchi, C. Giovani, E. Montomoli, D. Maione, L. Brito, A. Geall, M. Brazzoli, S. Bertholet; Siena, Italy WS.D.04.2 Single shot booster vaccinations against diphtheria do not induce sufficient long‑term protection in a large proportion of elderly people Marco Grasse, B. Weinberger, A. Meryk, B. Grubeck‑Loebenstein; Innsbruck, Austria WS.D.04.3 Targeted therapeutic approached to rheumatoid arthritis Ahuva Nissim; London, United Kingdom

WS.D.02.6 Systems biology approach to dissecting meningococcal vaccine responses O’Connor Daniel, E.A. Clutterbuck, D.F. Kelly, A.J. Pollard; Oxford, United Kingdom

nnWS.D.03

WS.D.03.5 RNA‑ and protein‑based vaccines induce CD8+ T cells with different gene expression profiles Trine Meldgaard, F. Blengio, C. Sammicheli, S. Tavarini, F. Corrente, S. Mangiavacchi, M. Brazzoli, E. de Gregorio, R. Rappuoli, A. Geall, E. Siena, S. Nuti, R. Kratzer, S. Bertholet; Siena, Italy

Hall M 15:45 – 17:00

Chairpersons: Christian Muenz; Zurich, Switzerland Ursula Wiedermann; Vienna, Austria WS.D.03.1 Local skin reactions as potential indicators of vaccine‑specific memory CD8+ T‑cell immune responses to influenza vaccination Helene Perrin, A. Soria, P. Loulergue, A. Rousseau, O. Bonduelle, M. Cachanado, L. Ben Slama, M. Dufossee, A. Vogt, S. Van Der Werf, S. Behillil, T. Simon, O. Launay, B. Combadiere, B. Combadiere; Paris, France

WS.D.04.4 IL‑37: therapeutic potential of a natural inhibitor of innate immunity during acute and chronic joint inflammation Marije I. Koenders, G. Cavalli, P.M. van der Kraan, W.B. van den Berg, L.A. Joosten, C.A. Dinarello; Nijmegen, Netherlands WS.D.04.5 NFATc1α is a key target to prevent acute rejection after cardiac transplantation J. Baur, U. Steger, T. Pusch, K. Murti, R. Busch, C. Germer, E. Serfling, C. Otto, Andris Avots; Wuerzburg, Germany WS.D.04.6 Role of NFATc activation in innate immune cells in acute transplant rejection Clara Cigni, F. Mingozzi, R. Marzi, I. Zanoni, F. Granucci; Milano, Italy

WS.D.03.2 Prime‑boost vaccination with viral vectors via heterologous route maximizes both tissue‑resident and circulating CD8+ T cell memory responses Nicolas Çuburu; Bethesda, United States WS.D.03.3 The kinetic of type I interferon responses regulates induction of adaptive immunity and antiviral memory Julia Spanier, P. Staeheli, U. Kalinke; Hannover, Germany WS.D.03.4 rVSV vaccine expressing Zaire ebola virus glycoprotein: Data from the phase I trial in Germany Christine Dahlke, M. Zinser, R. Kasonta, V. Krähling, A. Nolting, H.C. Stubbe, N. Biedenkopf, M. Eickmann, S.K. Fehling, T. Strecker, S. Borregard, A. Jambrecina, F.R. Stahl, S. Becker, A.W. Lohse, S. Schmiedel, M.M. Addo; Hamburg, Germany

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

57

MONDAY

nnWS.D.02

Program per Day

MONDAY, SEPT. 7, 2015 Joint-Symposia of the Day JOINT-SYMPOSIA OF THE DAY nnJS.01

OTHER SESSIONS AND MEETINGS

Molecular Mechanisms of the Immune Response to Infection (jointly with AAI) Hall A 14:00 – 15:30

EFIS Awards Lecture Symposium nnEF.01

MONDAY

Chairpersons: Jenny Ting; Chapel Hill, United States Georg Stingl; Vienna, Austria

ACTERIA Prizes and EFIS-EJI Ita Askonas Prize

Hall F2 14:00 – 15:30

JS.01.1

NLR family of innate immune sensors: impact on immunity and beyond Jenny Ting; Chapel Hill, United States

Chairpersons: Anne Hosmalin; Paris, France Catherine Sautès‑Fridman; Paris, France Lorenzo Moretta; Rome, Italy

JS.01.2

TCR signal strength regulates antiviral T cell responses via graded expression of IRF4 Leslie Berg; Worcester, United States

JS.01.3

Immunity to tuberculosis: a balancing act Shabaana Khader; St.Louis, United States

The EFIS-IL Most Cited Article and Review Prizes - Sagrario Martín-Aragón; Madrid, Spain / EFIS-IL Most Cited original Article - Girija Kuttan and K.S. Siveen; Kerala, India / EFIS-IL Most Cited Review

nnJS.02

Resolution of Inflammation (jointly with EULAR)

Hall E 14:00 – 15:30

Chairpersons: Christopher Buckley; Birmingham, United Kingdom Clemens Scheinecker; Vienna, Austria JS.02.1

Lack of resolution of inflammation: Explaining chronicity of human immune‑inflammatory diseases Christopher Buckley; Birmingham, United Kingdom

The EFIS/EJI Ita Askonas Prize EF.01.1 Follicular lymphoma cell niche: a criminal conspiracy of T cells and stromal cells Karin Tarte; Rennes, France The ACTERIA Prizes Awarded by EFIS EF.01.2 Characterization of allergens involved in IgE mediated wheat allergy Sandra Pahr; Vienna, Austria ACTERIA Doctoral Prize in Allergology EF.01.3

Too much, too little, or just enough: feedback control of aryl hydrocarbon receptor signalling in intestinal immunity Chris Schiering; London, United Kingdom ACTERIA Doctoral Prize in Immunology

JS.02.2

Resolution of inflammation by neutrophil NETosis ‑ a clue for understanding gout Martin Herrmann; Erlangen, Germany

JS.02.3

Fosterin anti‑inflammatory mechanisms to stop arthritis Fons van de Loo; Nijmegen, Netherlands

EF.01.4

From Magic Bullets to Targeted Therapy Approaches (Russian-Georgian-Austrian Sister Symposium) Hall M

Immunoglobulin E enhances host resistance to venom Thomas Marichal; Liege, Belgium ACTERIA Early Career Research Prize in Allergology

EF.01.5

Enhanced understanding of CD8 T cell differentiation and tolerance Dietmar Zehn; Lausanne, Switzerland ACTERIA Early Career Research Prize in Immunology

nnJS.03

14:00 – 15:30 Chairpersons: Revaz Sepiashvili; Moscow, Russian Federation Heimo Bereiteneder; Vienna, Austria JS.03.1

Modern ImmunoPharmacology: Magic bullets & combinatorial approaches Alexander G. Gabibov; Moscow, Russian Federation

JS.03.2

A new concept of tumor targeted delivery of visualizing and cytotoxic agents Deyev Sergey; Moscow, Russian Federation

JS.03.3

Camel single domain antibody‑based technological innovations for research, diagnostics and therapy Sergey Tillib; Moscow, Russian Federation

Scientific Writing Session nnSW.01

Hall F2 19:15 – 20:15

A paper that is well-written and that presents and discusses the data in a clear and structured manner makes the life of an editor (and reviewers) much easier. Precise writing doesn’t guarantee that your paper will be accepted – that depends on the significance and validity of the results – but it does create a good first impression. Importantly, clear writing prevents potential misunderstandings that could, in the worst case scenario, result in your paper being rejected. This session, which is aimed primarily at PhD students/early postdocs, will provide examples and tips of good scientific writing. Speaker:

58

Titles to Figure Legends: An Insider's Guide to Publishing

Dr. Karen Chu, Associate Editor, European Journal of Immunology

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

MONDAY, SEPT. 7, 2015 Business and Ancillary Meetings BUSINESS AND ANCILLARY MEETINGS nnBA.07

DGfI Study Groups Board Meeting

closed* nnBA.08

Meeting Room 2 (1.61) 09:45 – 11:15 Dutch Society for Immunology (NVVI)

closed* Board Meeting nnBA.09

Meeting Room 3 (2.15) 09:45 – 11:15

Scandinavian Society for Immunology (SSI)

closed* nnBA.10

Meeting Room 6 (2.12) 09:45 – 11:15

MEET THE PROFESSOR BREAKFAST Informal breakfast event for early career scientists. The “Meet the Professor Sessions” will provide participants the opportunity to meet the most renowned senior scientists in an interactive and casual manner. Small breakfast will be provided. Registration is possible via email and onsite at a first-come-first-serve basis. Maximum amount of participants per breakfast: 30

nnME.01

Peter Openshaw

Meeting Room 1 (1.85-86) 07:15 – 08:15

European Journal of Immunology

nnBA.10.1

IUIS-Frontiers Partnership Meeting

closed* nnBA.11

Meeting Room 5 (2.17) 10:00 – 15:30 Scandinavian Society for Immunology (SSI)

closed* Retreat Follow-up Meeting

Meeting Room 6 (2.12) 12:30 – 13:30

nnBA.12

IUIS-EFIS Annual Collaboration Review Meeting

closed*

Meeting Room 2 (1.61) 15:30 – 17:00

nnBA.12.1

SIICA Board Meeting

closed* nnBA.13

Meeting Room 6 (2.12) 17:00 – 19:00 Scandinavian Journal of Immunology

Editorial Board Meeting (open to members of the respective society only) nnBA.14

Meeting Room 1 (1.85-86) 17:30 – 18:45

Italian Society of Immunology, Clinical Immunology and Allergology

(SIICA) General Assembly (open to members of the respective society only) nnBA.15

MONDAY

closed* Meeting Room 1 (1.85-86) Editorial Board and Alumni Meeting 10:00 – 11:00

Meeting Room 3 (2.15) 19:15 – 20:45

Hungarian Society for Immunology (MIT)

Board Meeting Meeting Room 6 (2.12) (open for all Hungarian participants) 19:15 – 20:45 * on invitation only

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

59

Program per Day

MONDAY, SEPT. 7, 2015 Posters of the Day according to Tracks A, B, C, D, E

MONDAY

POSTERS OF THE DAY ACCORDING TO TRACKS A, B, C, D, E

Track C – Innate Immunity nnP.C.01

Granulocytes

nnP.C.02

NK and NKT Cells - Part 1

Track A – Adaptive Immunity

nnP.C.03

Innate Lymphocytes

nnP.A.01

Lineage Commitment

nnP.C.04

Immune Suppression

nnP.A.02

Lymphocyte Tolerance and Memory

nnP.C.05

Dendritic Cell Biology - Part 1

nnP.A.03

Antigen Processing and Presentation - Part 1

nnP.C.06

Pattern Recognition Receptors - Part 1

nnP.A.04

Th1 and Th2 Cells - Part 1

nnP.C.07

Cytosolic Sensing and Inflammasome

nnP.A.05

Th17 Cells - Part 1

nnP.C.08

Cell Signaling - Part 1

nnP.A.06

Regulatory T Cells - Part 1

nnP.A.07

CD8+ T Cells - Part 1

nnP.A.08

γδ T Cells

nnP.A.09

Germinal Centre Reaction - Part 1

nnP.A.10

B Cells in Autoimmunity and Tolerance

Track B – Diseases nnP.B.01

Immunity to Bacterial Infection - Part 1

nnP.B.02

Immunity to Bacterial Infection - Part 2

nnP.B.03

Immunity to Fungi, Helminths and Malaria

nnP.B.04

Primary Immunodeficiencies - Part 1

nnP.B.05

Autoinflammatory Diseases

nnP.B.06

Diseases - Inflammation - Part 1

nnP.B.07

Neuroimmunology

nnP.B.08

Diabetes and (chronic) Inflammatory Joint Diseases

nnP.B.09

(Chronic) Inflammatory Joint Diseases - Part 1

nnP.B.10

Inflammatory Skin and Joint Diseases

nnP.B.11

Allergen Specific Immune Responses - Part 1

nnP.B.12

Allergic Disorders - Part 1

nnP.B.13

Tumor Immunity - Part 1

nnP.B.14

Tumorantigens and Tumorstroma

60

Track D – Disease Intervention nnP.D.01

Bone Marrow Transplantation and GVHD Part 1

nnP.D.02

Vaccines - Part 1

nnP.D.03

Vaccines & Veterinary Immunology - Part 1

nnP.D.04

Immune Interventions in Autoimmunity - Part 1

nnP.D.05

Intervention & Therapy of Allergy - Part 1

nnP.D.06

Cancer Immunotherapy - Part 1

nnP.D.07

Stem Cells & Cell Based Therapies - Part 1

nnP.D.08

Biomarkers of Human Immune Responses & Immunogenicity against Biopharmaceuticals Part 1

nnP.D.09

Bone Marrow Transplantation and GVHD Part 2

nnP.D.10

Immunomodulation by Nutrients & Vitamines

Track E – Other nnP.E.01

Structural Biology & Imaging of the Immune System

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

TUESDAY Schedule at a Glance Tuesday. . . . . . . . . . . . . . . . . . . . . . . . . 62 Keynote Lecture of the Day . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 Overview per Track. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 TUESDAY

Track A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65 Track B . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 Track C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 Track D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 Track E . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72 Joint-Symposia of the Day. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 Other Sessions and Meetings. . . . . . . . . . . . . . . . . . . . . . . . . . . 73 Business and Ancillary Meetings. . . . . . . . . . . . . . . . . . . . . . . . 73 Meet the Professor Breakfasts. . . . . . . . . . . . . . . . . . . . . . . . . . 74 Posters of the Day according to Tracks A, B, C, D, E . . . . . . . 74

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

61

Program per Day

TUESDAY, SEPT. 8, 2015 SCHEDULE AT A GLANCE TUESDAY

Tuesday, Sept. 8, 2015 Room

Hall A

Hall E

Hall F1

Hall F2

Hall G

Hall K

Level

2

0

0

0

-2

-2

07:15 – 08:15 08:15 – 08:30 08:30 – 08:45 08:45 – 09:00

S.A.03

Adaptive Immunity Immune Cell 09:15 – 09:30 Trafficking 09:00 – 09:15

S.B.03

Diseases Immunity Against Infections

WS.D.05

T Cell Based Cancer Immunotherapy

WS.C.07

Macrophage Signaling

WS.D.06

Stem Cells and CellBased Therapy

WS.C.08

Epigenetics in Innate Immunity

09:30 – 09:45 09:45 – 10:00 10:00 – 10:15 10:15 – 10:30

Poster Session and Guided Poster Walks / Coffee Break

10:30 – 10:45 10:45 – 11:00 11:00 – 11:15 11:15 – 11:30 11:30 – 11:45

S.C.03

11:45 – 12:00 Innate Immunity

Innate Effector

12:00 – 12:15 Functions

S.D.03

Disease Intervention Antibody Therapeutics

WS.A.06

Molecular & Cellular Control of CD8+ T Cells (part 2)

WS.B.06

Cytokines and Chemokines in Tumor Immunology

WS.A.07

WS.B.07

T Cell Signalling

Skin Diseases

12:15 – 12:30

TUESDAY

12:30 – 12:45 12:45 – 13:00 13:00 – 13:15

KL.B.1

Diseases

13:15 – 13:30 Inflammasome 13:30 – 13:45 13:45 – 14:00 14:00 – 14:15

JS.04

14:15 – 14:30 International Union 14:30 – 14:45 14:45 – 15:00 15:00 – 15:15 15:15 – 15:30

of Immunological Societies (IUIS) Vaccine Development Can Benefit from Computational Biology

JS.05

European Academy of Allergy and IS.07 Clinical Immunology (Industry Sponsored)* (EAACI) T Helper Cell Subsets in Health and Disease

JS.06

International Society for the Advancement of Cytometry (ISAC) Cytometry of the 21st Century

JS.07

Society for Mucosal Immunity (SMI) The Mucosal Microbiome in Health and Disease

15:30 – 15:45 15:45 – 16:00 16:00 – 16:15

S.A.04

16:15 – 16:30 Adaptive Immunity

Establishment of 16:30 – 16:45 B Cell Responses

S.B.04

Diseases Primary Immunodeficiencies

WS.D.07

Novel Approaches for Vaccines

WS.C.10

Macrophages in Diseases

WS.C.11

WS.B.09

WS.B.11

WS.A.11

Innate Lymphoid Cells

Optimizing Anti‑Tumor Immunity

16:45 – 17:00 17:00 – 17:15

Coffee Break

17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 18:00 – 18:15

S.C.04

18:15 – 18:30 Innate Immunity

Antigen Uptake and

18:30 – 18:45 Presentation

S.D.04

Disease Intervention Cancer Immunotherapy

WS.A.10

WS.B.10

Treg Induction / Subsets

Systemic Autoimmune Diseases

Allergens

B Cell Signaling

18:45 – 19:00 19:00 – 19:15 19:15 – 19:30 19:30 – 19:45 19:45 – 20:00 20:00 – 20:15 20:15 – 20:30

Heurigen Evening

20:30 – 20:45 20:45 – 21:00 21:00 – 21:15 21:15 – 21:30

* please see page 99 for details

62

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

TUESDAY, SEPT. 8, 2015 SCHEDULE AT A GLANCE TUESDAY

Tuesday, Sept. 8, 2015 Hall M

Hall N

1

1

Meeting Room Meeting Room Meeting Room Meeting Room 1 3 5 6 (1.85-86) (2.15) (2.17) (2.12) 1

ME.02

Jürgen Wienands

2

ME.03

Ron Germain

2

ME.04

Nadine Cerf-Bensussan

2

L7

Room

1

Level

ME.05

07:15 – 08:15

Luke O’Neill

08:15 – 08:30 08:30 – 08:45

WS.C.09

WS.E.01

Structural Biology and Imaging

08:45 – 09:00

Innate Cell Signalling & Function

09:00 – 09:15 09:15 – 09:30 09:30 – 09:45 09:45 – 10:00

Poster Session IS.06 BA.16 BA.17 BA.19 and Scandinavian German Society Belgian (Industry BA.18 Guided Sponsored Progress Society for for Immunology Immunological French Society of BA.19.1 Immunology (SSI) (DGfI) Society (BIS) Poster Walks / in Technology Immunology (SFI) IUIS Quality Session)* General Assembly General Assembly General Assembly Coffee Break Annual board Assessment and meeting

WS.A.08

B Cell Development & Homeostasis

WS.B.08

Standardization Committee Meeting

10:00 – 10:15 10:15 – 10:30 10:30 – 10:45 10:45 – 11:00 11:00 – 11:15 11:15 – 11:30 11:30 – 11:45

Innate Immune Mechanisms in Cancer

11:45 – 12:00 12:00 – 12:15 12:15 – 12:30

12:45 – 13:00

EEIG ECI-EFIS Meeting

13:00 – 13:15 13:15 – 13:30 13:30 – 13:45 13:45 – 14:00 14:00 – 14:15

WO.00

Women in Immunology Carreer Talks

BA.21

EFIS General Assembly

WS.A.09

Molecular Control of T Cell Development

WS.D.08

Solid Organ and Bone Marrow Transplantation

Coffee Break

14:30 – 14:45 14:45 – 15:00 15:00 – 15:15 15:15 – 15:30 15:30 – 15:45 15:45 – 16:00 16:00 – 16:15 16:15 – 16:30

BA.22

Inaugural IUIS Vaccine Committee Meeting

16:30 – 16:45 16:45 – 17:00 17:00 – 17:15

BA.23

EFIS Board Meeting

17:15 – 17:30 17:30 – 17:45 17:45 – 18:00

WS.B.12

Models and Mechanisms of Primary Immunodeficiency

booked out!

14:15 – 14:30

18:00 – 18:15

WS.B.13

18:15 – 18:30

Immune Disorders

18:30 – 18:45 18:45 – 19:00 19:00 – 19:15 19:15 – 19:30 19:30 – 19:45 19:45 – 20:00

Heurigen Evening

20:00 – 20:15 20:15 – 20:30 20:30 – 20:45 20:45 – 21:00 21:00 – 21:15 21:15 – 21:30

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

63

TUESDAY

12:30 – 12:45

BA.20

Program per Day

TUESDAY, SEPT. 8, 2015 OVERVIEW PER TRACK

Keynote Lecture of the Day - KL.B.1 – Diseases 12:45 – 13:45 Chairperson:

Hall A Fiona Powrie; Oxford, United Kingdom

Inflammasome Luke O’Neill Trinity College Dublin, Department of Biochemistry and Immunology; Dublin, Ireland Professor Luke O’Neill was appointed to the Chair of Biochemistry at Trinity College Dublin in 2008, where he leads the Inflammation Research Group. He has a PhD in Pharmacology from the University of London and carried out Post-Doctoral research at Cambridge, U.K., on the pro-inflammatory cytokine IL-1 and innate immune signaling. His research is in the area of the molecular basis to inflammatory diseases. He has won numerous awards for his research, notably the Royal Irish Academy Medal for Biochemistry, The Irish Society for Immunology medal, the Royal Dublin Society/ Irish Times Boyle medal for Scientific Excellence, the Science Foundation Ireland Researcher of the Year Award and in 2014 the European Federation of Immunology Societies Medal. He was elected a member of EMBO in 2005. In 2014 he was named by Thompson Reuters as one of the world’s most influential scientists, being in the top 1% in both Immunology and Pharmacology/Toxicology. He is a co-founder and director of Opsona Therapeutics, a drug development company working in the area of Toll-like receptors.

TUESDAY

OVERVIEW PER TRACK TRACK A – ADAPTIVE IMMUNITY

TRACK C – INNATE IMMUNITY

Symposia S.A.03 Immune Cell Trafficking S.A.04 Establishment of B Cell Responses

Symposia S.C.03 Innate Effector Functions S.C.04 Antigen Uptake and Presentation

Workshops WS.A.06 WS.A.07 WS.A.08 WS.A.09 WS.A.10 WS.A.11

Workshops WS.C.07 WS.C.08 WS.C.09 WS.C.10 WS.C.11

Molecular & Cellular Control of CD8+ T Cells - Part 2 T Cell Signalling B Cell Development & Homeostasis Molecular Control of T Cell Development Treg Induction / Subsets B Cell Signaling

TRACK B – DISEASES Symposia S.B.03 Immunity Against Infections S.B.04 Primary Immunodeficiencies Workshops WS.B.06 Cytokines and Chemokines in Tumor Immunology WS.B.07 Skin Diseases WS.B.08 Innate Immune Mechanisms in Cancer WS.B.09 Optimizing Anti-Tumor Immunity WS.B.10 Systemic Autoimmune Diseases WS.B.11 Allergens WS.B.12 Models and Mechanisms of Primary Immunodeficiency WS.B.13 Immune Disorders

64

Macrophage Signaling Epigenetics in Innate Immunity Innate Cell Signalling & Function Macrophages in Diseases Innate Lymphoid Cells

TRACK D – DISEASE INTERVENTION Symposia S.D.03 Antibody Therapeutics S.D.04 Cancer Immunotherapy Workshops WS.D.05 WS.D.06 WS.D.07 WS.D.08

T Cell Based Cancer Immunotherapy Stem Cells and Cell-based Therapy Novel Approaches for Vaccines Solid Organ and Bone Marrow Transplantation

TRACK E – OTHER Workshop WS.E.01 Structural Biology and Imaging

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

TUESDAY, SEPT. 8, 2015 Track A

Symposia nnS.A.03

Immune Cell Trafficking

Hall A 08:30 – 09:45

Chairpersons: Ronen Alon; Rehovot, Israel Britta Engelhardt; Bern, Switzerland S.A.03.1

DC and B cell trafficking Reinhold Förster; Hannover, Germany

S.A.03.2

T cell trafficking Ronald N. Germain, T. Laemmermann, P. Torabi‑Parizi, T. Honda, J. Egen, Z. Liu, A.Y. Rudensky, A. Levine, W. Li, M.Y. Gerner; Bethesda, United States

S.A.03.3

Immune cell‑to‑cell communication: Mechanisms of microRNA and proteins sorting into exosomes Francisco Sánchez‑Madrid; Madrid, Spain

nnS.A.04

Establishment of B Cell Responses

Hall A

15:45 – 17:00 Chairpersons: Rita Carsetti; Rome, Italy Simon Fillatreau; Berlin, Germany S.A.04.1

Control of plasma cell differentiation by the transcription factor Blimp1 M. Minnich, H. Tagoh, P. Bönelt, E. Axelsson, M. Fischer, M. Jaritz, Meinrad Busslinger; Vienna, Austria

S.A.04.2

Human Marginal Zone B Cells Jean C. Weill; Paris, France

S.A.04.3

Germinal center formation Balbino Alarcon; Madrid, Spain

Molecular & Cellular Control of CD8+ T Cells - Part 2

Hall F1 11:15 – 12:30

Chairpersons: Axel Kallies; Parkville, Australia Thomas Schüler; Magdeburg, Germany WS.A.06.1 Mitochondrial biogenesis in naive CD8+ T cells occurs early after activation and before the first division Marco Fischer, G.R. Bantug, L. Razik, R. Belle, S. Dimeloe, J. Graehlert, U. Sauders, C. Hess; Basel, Switzerland WS.A.06.2 T cell cross‑reactivity between a highly immunogenic Epstein‑Barr virus epitope and a self‑peptide naturally presented by HLA‑B*18:01+ cells Scott R. Burrows, M.J. Rist, K.M. Hibbert, N.P. Croft, A.W. Purcell, J. Rossjohn; Brisbane, Australia WS.A.06.3 The MAZR/Runx3 complex is integrated into the transcriptional network controlling effector CD8+ T cell differentiation Shinya Sakaguchi, C. Tizian, D. Hainberger, K. Khamina, T. Penz, C. Bock, I. Taniuchi, A. Bergthaler, W. Ellmeier; Vienna, Austria WS.A.06.4 Immunosurveillance of the liver by intravascular effector CD8+ T cells Matteo Iannacone; Milan, Italy

www.eci-vienna2015.org

WS.A.06.6 CD11b+ dermal dendritic cells are competent to induce protective skin homing CD8+ T Cells Tobias Hain, S. Muth, F. Melchior, H. Schild, H. Probst; Mainz, Germany

nnWS.A.07

T Cell Signalling

Hall G 11:15 – 12:30

Chairpersons: Burkhart Schraven; Magdeburg, Germany Nicole Boucheron; Vienna, Austria WS.A.07.1 Lipid in T‑cell receptor transmembrane signaling H. Li, X. Guo, C. Yan, X. Shi, C. Wong, J. Chou, Y. Cao, Chenqi Xu; Shanghai, China WS.A.07.2 PTPN22: a sticking point during integrin signalling in T lymphocytes Garth L. Burn, G. Cornish, L. Svensson, D. Owen, A.P. Cope; London, United Kingdom WS.A.07.3 Phosphatidylinositol 4‑phosphate 5‑kinase (PIP5Kα) and Vav1: critical regulators of CD28‑mediated signaling functions Nicla Porciello, M. Muscolini, C. Camperio, S. Caristi, C. Capuano, A. Viola, R. Galandrini, L. Tuosto; Rome, Italy WS.A.07.4 Proteomic analysis revealed Vav1 as a key effector of CD226 signaling in CD4 T cells Guillaume Gaud, R. Roncagalli, J. Familiades, A. Gonzalez de Peredo, K. Chaoui, C. Colacios, B. Malissen, A. Saoudi; Toulouse, France

Workshops nnWS.A.06

WS.A.06.5 Hobit and Blimp‑1 mediate a unified transcriptional program of tissue‑residency in lymphocytes L. Mackay, M. Minnich, C. Seillet, B. Nota, W. Shi, J. Liao, A. Braun, T. Gebhardt, S. Preston, M. Pellegrini, D. Pellicci, D. Godfrey, G. Belz, M. Busslinger, F. Carbone, R. van Lier, N. Kragten, A. Kallies, Klaas van Gisbergen; Amsterdam, Netherlands

WS.A.07.5 The deubiquination of SMAD7 by CYLD is required for T cell homeostasis and canonical TGF‑β signaling Yilang Tang, S. Reißig, A. Waisman; Mainz, Germany WS.A.07.6 Neuroserpin expressed by human T cells regulates the proteolytic balance controlling homotypic T cell interactions. Evert J. Loef, N. Lorenz, A.E. Brooks, R. Dunbar, N.P. Birch; Auckland, New Zealand

nnWS.A.08

B Cell Development & Homeostasis

Hall M

11:15 – 12:30 Chairpersons: Andreas Radbruch; Berlin, Germany Klaus Rajewsky; Berlin, Germany WS.A.08.1 Mapping the human liver B cell compartment in health and disease Sudha Purswani, G. Reynolds, J. Harris, R. Smith, S. Davies, E. Triantafyllou, K. Petrovic, B. Wiggins, G. Webb, E. Liaskou, D. Adams, Z. Stamataki; Birmingham, United Kingdom WS.A.08.2 IL4I1 slows‑down BCR crosslinking and regulates B cell homeostasis Lloyd Bod, R. Lengagne, L. Douguet, V. Molinier‑Frenkel, F. Castellano, Y. Richard, A. Prévost‑Blondel; Paris, France

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

65

TUESDAY

TRACK A

Program per Day

TUESDAY, SEPT. 8, 2015 Track A WS.A.08.3 B‑cell survival is controlled by tetraspanin CD37; implications for lymphomagenesis C. de Winde, S. Veenbergen, K. Young, M. van den Brand, A. van der Schaaf, N. Muthusamy, D. Tarlinton, H. van Krieken, M. Wright, C. Figdor, Annemiek van Spriel; Nijmegen, Netherlands WS.A.08.4 Testing Bim as a functional target of miR‑17‑92 in B cells Verena Labi, F. Klironomos, S. Peng, T. Chakraborty, M. Munschauer, A. Villunger, M. Landthaler, N. Rajewsky, K. Rajewsky; Innsbruck, Austria WS.A.08.5 Microprocessor component DGCR8 is essential for early B cell development W. Schuh, A. Brandl, S. Brenner, Patrick Daum, M. Bösl, J. Wittmann, H. Jäck; Erlangen, Germany WS.A.08.6 Early B cell development requires balanced expression of miR‑191 Jonas Blume, M. Lyszkiewicz, K. Witzlau, A. Krueger; Hannover, Germany

nnWS.A.09

Molecular Control of T Cell Development

Hall M 15:45 – 17:00

TUESDAY

Chairpersons: Thorsten Buch; Zurich, Switzerland Adrian Hayday; London, United Kingdom WS.A.09.1 The actin remodeling protein cofilin is crucial for early T‑cell development Isabel John, D. Deibel, S. Prokosch, G. Küblbeck, B. Arnold, Y. Samstag; Heidelberg, Germany

WS.A.10.2 IL‑1R1 is expressed on both Helios+ and Helios‑ FOXP3+ CD4+ T cells in the rheumatic joint M. Müller, J. Herrath, Vivianne Malmström; Stockholm, Sweden WS.A.10.3 Ex‑Th17 Foxp3+ T cells ‑ a novel subset of Foxp3+ T cells in sterile inflammation Natasa Obermajer, S. Downs‑Canner, R. Ravindranathan, F.C. Popp, Y. Soeder, J. Haarer, E.K. Geissler, H.J. Schlitt, R.P. Edwards, K. Odunsi, P. Kalinski, M.H. Dahlke, D.L. Bartlett; Pittsburgh, United States WS.A.10.4 Generation and maintenance of tissue regulatory T cells D.F. Pinheiro, S.K. Kitzmueller, M.M. Maurano, M.M. Klicznik, R. Holly, G. Achatz‑Straussberger, A.K. Abbas, Iris K. Gratz; Salzburg, Austria WS.A.10.5 IL‑2/Blimp‑1/mir9 axis regulates IL‑10 expression in CD39+ Tregs Chansavath Phetsouphanh, D.D. Murray, D.C. Hsu, Y. Xu, L. Cook, J. Zaunders, A. Kelleher, N. Seddiki; Kensington, Australia WS.A.10.6 Cholera toxin mediates cAMP‑dependent CTLA‑2 secretion by dendritic cells to enhance regulatory T cell conversion C. Silva Vilches, T. Müller, J. Bodem, Manfred B. Lutz; Würzburg, Germany

nnWS.A.11

B Cell Signaling

Hall K 17:45 – 19:00

Chairpersons: Lars Nitschke; Erlangen, Germany Gertrude Achatz‑Straussberger; Salzburg, Austria

WS.A.09.2 Characterizing the functional role of WWOX in thymocyte development Tsung Hao Chang, L. Hsu; Tainan, Taiwan WS.A.09.3 MAZR and Runx factors synergistically repress ThPOK during CD8+ T cell lineage development S. Sakaguchi, Daniela Hainberger, C. Tizian, H. Tanaka, T. Okuda, I. Taniuchi, W. Ellmeier; Vienna, Austria

WS.A.11.1 New roles of MALT1 proteolysis in B cell function deciphered using multiplexed N‑terminal proteomics using TAILS Theo Klein, S.Y. Fung, F. Renner, M.A. Blank, R.I. Viner, C.H. Regnier, S.E. Turvey, C.M. Overall; Vancouver, Canada

WS.A.09.4 TCR/CD3 signaling requirements for thymic γδ T cell effector differentiation Miguel Muñoz‑Ruiz, J. Ribot, D.J. Pennington, J.R. Regueiro, E. Fernández Malavé, B. Silva Santos; Madrid, Spain

WS.A.11.2 Ly9 (CD229) functions as a regulator controlling innate B cell homeostasis and antibody responses Marta Cuenca, X. Romero, J. Sintes, P. Engel; Barcelona, Spain

WS.A.09.5 Does CXCL8 production define a stage in human T cell development? A. Das, G. Lavender, C. Furness, T. Hayday, M. Greaves, A.C. Hayday, Deena L. Gibbons; London, United Kingdom

WS.A.11.3 Cdc42 is an essential regulator of antiviral humoral immunity. Marianne Burbage, S.J. Keppler, F. Gasparrini, N. Martínez‑Martín, M. Gaya, C. Feest, M. Domart, L. Collinson, A. Bruckbauer, F.D. Batista; London, United Kingdom

WS.A.09.6 TECs are a non‑redundant source of Wnt ligands in the thymus Fabian Brunk, I. Augustin, M. Meister, M. Boutros, B. Kyewski; Heidelberg, Germany

nnWS.A.10

Treg Induction / Subsets

Hall F1 17:45 – 19:00

Chairpersons: Petra Hoffmann; Regensburg, Germany Pascale Plence; Montpellier, France WS.A.10.1 ILT‑3 expressing regulatory T cells, steered by Protein Kinase CK2, fail to control vigorous Th2 responses in vivo Alexander Ulges, T. Bopp; Mainz, Germany

66

WS.A.11.4 DEC1 as a master regulator of B lymphocyte activation and apoptosis Laura Todi, C. Lazzeri, C. Cristofoletti, A. Camponeschi, R. Marrapodi, M. Del Padre, M. Mitrevski, M. Fiorilli, M. Visentini; Rome, Italy WS.A.11.5 HAX1 deletion affects BCR‑internalization by leading to delayed BCR‑mediated apoptosis Gertrude Achatz‑Straussberger, I.K. Gratz; Salzburg, Austria WS.A.11.6 Enhanced Bruton’s tyrosine kinase expression in B cells drives autoimmunity by disrupting T cell homeostasis O. Corneth, M.J. De Bruijn, M. Lukkes, J. Rip, P. Asmawidjaja, E. Lubberts, G.M. Verstappen, H. Bootsma, F.G. Kroese, L.P. Kil, Rudi W. Hendriks; Rotterdam, Netherlands

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

TUESDAY, SEPT. 8, 2015 Track B TRACK B

WS.B.06.6 TH9 cells drive IL‑9 mediated colitis‑associated colorectal cancer (CAC) Katharina Gerlach, S. Wirtz, A. McKenzie, M.F. Neurath, B. Weigmann; Erlangen, Germany

Symposia nnS.B.03

Immunity Against Infections

Hall E

nnWS.B.07

Skin Diseases

Hall K 11:15 – 12:30

08:30 – 09:45 Chairpersons: Brigitte Autran; Paris, France George Kassiotis; London, United Kingdom

Chairpersons: Karin Loser; Münster, Germany Georg Stary; Vienna, Austria

S.B.03.1

HCMV‑specific immunity Rene van Lier; Amsterdam, Netherlands

S.B.03.2

HIV‑specific immunity Philip Goulder; Oxford, United Kingdom

WS.B.07.1 Hair follicle epithelial cells are responsible for chronic inflammation in acne inversa Michele Boniotto, C. Hotz, A. Guguin, M. Surenaud, F. Jean‑Louis, P. Tisserand, P. Wolkenstein, H. Hocini, Y. Lévy, S. Hüe; Créteil, France

S.B.03.3

Inflammation in tuberculosis Stefan H.E. Kaufmann; Berlin, Germany

Primary Immunodeficiencies

Hall E 15:45 – 17:00

Chairpersons: Genevieve de Saint Basile; Paris, France Martha Eibl; Vienna, Austria S.B.04.1

Antibody deficiencies in man Bodo Grimbacher; Freiburg, Germany

S.B.04.2

Immune disorder and enteropathy resulting from TTC7A‑deficiency R. Lemoine, A.E. Bigorgne, M. El‑Daher, C. Leveau, H.F. Farin, F.E. Sepulveda, A. Fischer, Genevieve de Saint‑Basile; Paris, France

S.B.04.3

Neutrophil defects in man Kaan Boztug; Vienna, Austria

Cytokines and Chemokines in Tumor Immunology

WS.B.07.4 The role of basophils and dendritic cells in atopic dermatitis C. Schwartz, Jörg U. Eberle, T. Hoyler, A. Diefenbach, M. Lechmann, D. Voehringer; Erlangen, Germany WS.B.07.5 Functional beta2‑integrins restrict skin inflammation in vivo Terhi S. Savinko, V.L. Morrison, L.M. Uotila, C.J. Wolff, H.T. Alenius, S.C. Fagerholm; Helsinki, Finland

Workshops nnWS.B.06

WS.B.07.3 Tight interplay of actin cytoskeleton and filaggrin control epidermal differentiation and cornification as revealed by quantitative nanoscopy Danuta Gutowska‑Owsiak, J.B. de la Serna, M. Fritzsche, C. Eggeling, G.S. Ogg; Oxford, United Kingdom

Hall F2 11:15 – 12:30

WS.B.07.6 IgE autoreactivity in bullous pemphigoid Patricia C. Freire, P. Heil, G. Stingl; Vienna, Austria

Chairpersons: Vito Pistoia; Genoa, Italy Maria Sibilia; Vienna, Austria

nnWS.B.08

WS.B.06.1 The atypical chemokine receptor 2 promotes breast cancer lung metastatization through modulation of the metastatic niche Matteo Massara, B. Savino, N. Caronni, O. Bonavita, C. Recordati, A. Mantovani, M. Locati, R. Bonecchi; Rozzano, Italy

Chairpersons: Sophie Ugolini; Marseille, France Mathias Müller; Vienna, Austria

WS.B.06.2 TNF and IFN‑γ‑dependent signaling pathways in cytokine‑induced cancer cell senescence Heidi Braumueller, N. Simon, M. Rentschler, T. Wieder, E. Brenner, M. Röcken; Tuebingen, Germany WS.B.06.3 Notch1 and IL‑7R interplay in the pathogenesis of T‑cell acute lymphoblastic leukemia Marta Mosquera‑Sáiz, S. González‑García, J. Alcain, P. Fuentes, M. García‑Peydró, B. De Andrés, M.L. Gaspar, A. Corcoran, M.L. Toribio; Madrid, Spain WS.B.06.4 The IL‑25/IL‑25R axis in B cell lymphomas of germinal centre origin E. Ferretti, E. Di Carlo, C. Tripodo, M. Ponzoni, Vito Pistoia; Genova, Italy WS.B.06.5 Extracellular HSP110 from colorectal cancer cells skew macrophages polarization Kevin Berthenet, C. Garrido, G. Jego; Dijon, France

www.eci-vienna2015.org

TUESDAY

nnS.B.04

WS.B.07.2 Lesional skin of psoriatic patients is characterized by an overexpression of IL‑17E producing keratinocytes and IL‑17E positive dermal macrophages Nicolo C. Brembilla, R. Stalder, M. Fernandez, B. Shafaeddin Schreve, D. Alvarez Martinez, L. Fontao, G. Kaya, C. Chizzolini, W. Boehncke; Geneva, Switzerland

Innate Immune Mechanisms in Cancer

Hall N 11:15 – 12:30

WS.B.08.1 Treatment with BRAF inhibitor impacts on melanoma cell immunogenicity to NK cells Marina Colombo, E. Neves, A. Frazao, M. Messaoudene, F. Bouquet, A. Savina, M. Avril, A. Caignard; Paris, France WS.B.08.2 In vivo tumour surveillance by NK cells requires Tyk2 but not its kinase activity Agnieszka Witalisz‑Siepracka, M. Prchal‑Murphy, K.T. Bednarik, E.M. Putz, D. Gotthardt, K. Meissl, V. Sexl, M. Müller, B. Strobl; Vienna, Austria WS.B.08.3 A genome‑wide shRNA screening identifies novel potential ligands for activating NK cell receptors Paolo Romania, L. Cifaldi, E. Giorda, D. Fruci, F. Locatelli; Rome, Italy WS.B.08.4 TLR7 promotes tumor progression, chemotherapy resistance, and poor clinical outcomes in non‑small cell lung cancer M. Dajon, K. Iribarren, D. Damotte, C. Sautès‑Fridman, H. Fridman, Isabelle Cremer; Paris, France

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Program per Day

TUESDAY, SEPT. 8, 2015 Track B WS.B.08.6 IL‑27 induces the expression of immune‑regulatory molecules in ovarian cancer Silvano Ferrini, G. Carbotti, D. Mezzanzanica, I. Airoldi, M. Fabbi; Genova, Italy

nnWS.B.09

Optimizing Anti-Tumor Immunity

Hall K

15:45 – 17:00 Chairpersons: Christine S. Falk; Hannover, Germany Annemiek von Spriel; Nijmegen, Netherlands WS.B.09.1 Cytotoxic T‑cell transfer in combination with programd cell death 1 blockade eradicates chronic myelogenous leukemia stem cells Carsten Riether, T. Gschwend, A. Huguenin, C.M. Schuerch, A.F. Ochsenbein; Bern, Switzerland WS.B.09.2 The cold shock protein YB‑1 (Y‑box binding protein 1) regulates resistance against apoptosis in T‑lymphocytes Stefan Meltendorf, S. Gieseler, J. Handschuh, M. Pierau, P.R. Mertens, U. Thomas, M.C. Brunner‑Weinzierl; Magdeburg, Germany

TUESDAY

WS.B.09.3 CXCR4 inhibition in tumor microenvironment facilitates anti‑PD‑1 immunotherapy in sorafenib‑treated hepatocellular carcinoma in mice Rakesh R. Ramjiawan, T. Reiberger, Y. Chen, M.R. Ng, T. Hato, H. Ochiai, S. Kitahara, E.C. Unan, T.P. Reddy, C. Fan, P. Huang, N. Bardeesy, A.X. Zhu, R.K. Jain, D.G. Duda; Amsterdam, Netherlands WS.B.09.4 Exchange of cytosolic content between T cells and tumor cells activates CD4 T cells and impedes cancer growth Thorsten Lieke, M. Hardtke‑Wolenski, L. Kraus, C. Schmetz, B. Trautewig, F. Noyan, H. Bektas, F. Vondran, E. Jäckel; Hannover, Germany WS.B.09.5 Breadth of melanoma antigen expression determines clinical outcome following immunotherapy Antonia L. Pritchard, J. Burel, M. Neller, N. Hayward, M. Fatho, V. Lennerz, T. Wolfel, C. Schmidt; Brisbane, Australia

nnWS.B.10

Systemic Autoimmune Disease

Hall F2 17:45 – 19:00

Chairpersons: Wlodzimierz Maslinski; Warsaw, Poland Andrey I. Tchorbanov; Sofia, Bulgaria WS.B.10.1 Crosstalk between isoaspartyl modification and phosphorylation in ZAP70‑mediated lupus T cell autoimmunity Mei‑Ling Yang, M.J. Mamula; New Haven, United States WS.B.10.2 Defective autophagy in lymphocytes from patients with SLE causes accelerated apoptosis, impaired efferocytosis, and reduced induction of an anti‑inflammatory immune response. Joanne E. Simpson, K. Phadwal, M. Gray; Edinburgh, United Kingdom WS.B.10.3 Suppression of autoreactive cells by antibody therapy in MRL/lpr murine model of systemic lupus erythematosus N. Mihaylova, S. Bradyanova, P. Chipinski, S. Chausheva, M. Herbáth, F. D’Acquisto, J. Prechl, Andrey I. Tchorbanov; Sofia, Bulgaria

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WS.B.10.4 IL‑3 contributes to development of lupus nephritis in MRL/lpr mice Kerstin Renner, F. Hermann, K. Schmidbauer, Y. Talke, M. Rodriguez Gomez, G. Schiechl, J. Schlossmann, H. Brühl, H. Anders, M. Mack; Regensburg, Germany WS.B.10.5 Altered micro‑RNA‑21 expression contributes to the inflammatory environment observed in patients with primary Sjögren‘s syndrome Joan N. Gabhann, Q. Pilson, C.C. Murphy, C.A. Jefferies; Dublin, Ireland WS.B.10.6 A critical involvement of regulatory B cells in the pathogenesis of experimental Sjogren’s syndrome Liwei Lu; Hong Kong, Hong Kong

nnWS.B.11

Allergens

Hall G 17:45 – 19:00

Chairpersons: Heimo Breiteneder; Vienna, Austria Hans Grönlund; Stockholm, Sweden WS.B.11.1 A new fungal aspartic protease allergen Rhi o 1 and its IgE epitopes: the first major allergen from Rhizopus oryzae Gaurab Sircar, S. Gupta Bhattacharya; Kolkata, India WS.B.11.2 Heme‑induced polyreactivity of IgE antibodies Maya Hadzhieva, T. Vassilev, L. Roumenina, S. Lacroix‑Desmazes, J. Dimitrov; Sofia, Bulgaria WS.B.11.3 Characterization of the allergic T cell response to Dau c 1, the Bet v 1 homolog in carrot Nora Zulehner, B. Nagl, G. Zlabinger, B. Bohle; Vienna, Austria WS.B.11.4 Biochemical and biophysical characterization of recombinant CD23 in the trimeric complex with IgE and allergen Regina Selb, T. Twaroch, A. Teufelberger, C. Lupinek, B. Linhart, J. Eckl‑Dorna, W. Keller, A. Ellinger, K.H. Roux, V. Niederberger, R. Valenta; Vienna, Austria WS.B.11.5 The sensitization pattern and cross‑reactivity profiles of allergenic pectate lyases U. Pichler, M. Hauser, M. Wolf, M. Bernardi, G. Gadermaier, R. Weiss, C. Ebner, H. Yokoi, T. Takai, A. Didierlaurent, C. Rafaiani, P. Briza, A. Mari, H. Behrendt, F. Ferreira, Michael Wallner; Salzburg, Austria WS.B.11.6 Towards the characterization of the allergenic activity of carbohydrate‑reactive IgE Pia Gattinger, I. Mittermann, S. Pahr, W. Keller, B. Linhart, R. Valenta; Vienna, Austria

nnWS.B.12

Models and Mechanisms of Primary Immunodeficiency

Hall M 17:45 – 19:00

Chairpersons: Kaan Boztug; Vienna, Austria Géraldine Schlecht‑Louf; Clamart, France WS.B.12.1 EVER2 deficiency leads to altered T cell differentiation Myriam Hayder, B. Pignolet, A. Barbaria, E. Mauré, M. Vocanson, J. Nicolas, R.S. Liblau; Toulouse, France WS.B.12.2 Selective deficiency of WASP in Treg cells is sufficient to cause autoimmunity in mice Stefano Volpi, F. Beca, M. Mizui, K. Capuder, E. Santori, E. Csizmadia, A. Thrasher, F. Candotti, L. Notarangelo; Epalinges, Switzerland

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

TUESDAY, SEPT. 8, 2015 Track C

WS.B.12.4 IFNγ drives disease in TLR9‑mediated secondary hemophagocytic lymphohistiocytosis (sHLH) in mice Vanessa Buatois, L. Chatel, L. Cons, F. Richard, C. Bracaglia, F. De Benedetti, C. de Min, M. Kosco‑Vilbois, W. Ferlin; Geneva, Switzerland WS.B.12.5 Mouse cytomegalovirus infection in BALB/c mice resembles virus‑associated secondary hemophagocytic lymphohistiocytosis (HLH) and shows a pathogenesis distinct from primary HLH Ellen Brisse, M. Imbrechts, K. Put, A. Avau, T. Mitera, C.H. Wouters, G. Andrei, P. Matthys; Leuven, Belgium WS.B.12.6 STIM1 controls T cell‑mediated immune regulation and inflammation in chronic infection Carl Weidinger, L. Desvignes, P. Shaw, M. Vaeth, T. Ribierre, M. Lui, T. Ferrgus, L. Kozhaya, L. McVoy, D. Unutmaz, J. Ernst, S. Feske; Berlin, Germany

nnWS.B.13

Immune Disorders

Hall N 17:45 – 19:00

Chairpersons: Josef Penninger; Vienna, Austria Gerhard Zlabinger; Vienna, Austria WS.B.13.1 Characterization of novel PI3Kd inhibitors as potential therapeutics for SLE and lupus nephritis Philipp Haselmayer, M. Camps, M. Muzerelle, R. Grenningloh, H. Ji; Darmstadt, Germany WS.B.13.2 Persistent expression and function of P‑glycoprotein on peripheral blood lymphocytes identifies corticosteroid resistance in corticosteroid naïve patients with systemic lupus erythematosus Mohit K. Rai; Lucknow, India WS.B.13.3 A pore ring mutation in the protein‑conducting Sec61 channel is causing plasma cell deficiency in humans. Desirée Schubert, J. Kemming, S. Hassdenteufel, M. Klein, J. Kühn, M. Fliegauf, S. Winzer, A. Schäffer, J. Puck, R. Hostoffer, A. Köttgen, M. Rizzi, H. Eibel, R. Zimmermann, B. Grimbacher; Freiburg, Germany WS.B.13.4 Dual functionality of Mer in experimental arthritis: anti‑inflammatory signaling and efferocytosis Claire E.J. Waterborg, S. Beermann, M.B. Bennink, G. Lemke, F.A. van de Loo; Nijmegen, Netherlands WS.B.13.5 The tumor suppressor Hace1 controls intestinal homeostasis by mediating TNF‑driven cell fate Luigi Tortola, R. Nitsch, I. Kozieradzki, I. Uribesalgo, M. Floderer, M.J. Bertrand, M. Daugaard, H. Klug, Y. Redouane, G. Wirnsberger, N. Takahashi, G. Superti‑Furga, A. Pichler, G. Kroemer, P. Vandenabeele, P.H. Sorensen, J.M. Penninger; Vienna, Austria WS.B.13.6 Angiotensin II promotes regulatory B cells in the presence of BAFF and reduces experimental atherosclerosis Padmapriya Ponnuswamy, J. Joffre, Y. Quang, B. Esposito, M. Dalloz, T. Tedder, A. Tedgui, C. Binder, Z. Mallat, H. Ait‑Oufella; Paris, France

www.eci-vienna2015.org

TRACK C Symposia nnS.C.03

Innate Effector Functions

Hall A 11:15 – 12:30

Chairpersons: Francesca Granucci; Milan, Italy James Philip Di Santo; Paris, France S.C.03.1

Macrophage function in parasitic infection Judith Allen; Edinburgh, United Kingdom

S.C.03.2

Mast cells and basophils Massimo Triggiani; Salerno, Italy

S.C.03.3

Effector functions of neutrophils Arturo Zychlinsky; Berlin, Germany

nnS.C.04

Antigen Uptake and Presentation

Hall A

17:45 – 19:00 Chairpersons: Thomas Brocker; Munich, Germany Sebastian Amigorena; Paris, France S.C.04.1 Cross‑presentation Christian Kurts; Bonn, Germany S.C.04.2

Antigen presentation via C-type lectins to design DC targeting vaccines Yvette van Kooyk; Amsterdam, Netherlands

S.C.04.3

How B cells capture, process and present antigens: a crucial role for cell polarity Anna Maria Lennon Dumenil; Paris, France

TUESDAY

WS.B.12.3 CXCR4 desensitization exerts subset‑specific control of dendritic cell homeostasis and function in vivo M. Roriz, J. Calmette, N. Pionnier, M. Aknin, M. Evrard, P. Hémon, F. Gaudin, K. Balabanian, L. Ng, F. Bachelerie, Géraldine Schlecht‑Louf; Clamart, France

Workshops nnWS.C.07

Macrophage Signaling

Hall F2 08:30 – 09:45

Chairpersons: Thomas Decker; Vienna, Austria Holger Heine; Borstel, Germany WS.C.07.1 Lysophosphatidylcholine acyltransferase (LPCAT) 2 regulates macrophage inflammatory gene expression in response to Toll‑like receptor stimulation Wondwossen Abate, M. Thanabalasingam, S. Jackson; Plymouth, United Kingdom WS.C.07.2 The embryonic journey toward tissue‑resident macrophage development Guillaume Hoeffel, J. Chen, Y. Lavin, D. Low, F.F. Almeida, P. See, A.E. Beaudin, E.C. Forsberg, M. Poidinger, F. Zolezzi, A. Larbi, L.G. Ng, J.K. Chan, M. Greter, B. Becher, I.M. Samokhvalov, M. Merad, F. Ginhoux; Singapore, Singapore WS.C.07.3 FLT1 signaling in metastasis‑associated macrophages activates an inflammatory signature that promotes breast cancer distal metastasis Bin‑Zhi Z. Qian, H. Zhang, J. Li, T. He, E. Yeo, R.A. Lang, J.W. Pollard; Edinburgh, United Kingdom WS.C.07.4 Early life antigen and adjuvant trafficking Floriane Auderset, B. Mastelic Gavillet, P. Lambert, C. Siegrist; Geneva, Switzerland

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Program per Day

TUESDAY, SEPT. 8, 2015 Track C WS.C.07.5 DNA polymerase µ protects macrophages from double‑strand DNA breaks produced during pro‑inflammatory activation Juan A. Calatayud‑Subias, C. Sebastian, S. Pereira‑Lopes, M. Serra, L. Valverde‑Estrella, A. Bernad, J. Lloberas, A. Celada; Barcelona, Spain WS.C.07.6 mTORC2 regulates macrophage polarization and the cellular energy metabolism Karl Katholnig, M. Hirtl, M. Hengstschläger, T. Weichhart; Vienna, Austria

nnWS.C.08

Epigenetics in Innate Immunity

Hall K 08:30 – 09:45

WS.C.08.1 Roquin regulates microRNA homeostasis in T lymphocytes Monika Srivastava; Canberra, Australia WS.C.08.2 MicroRNA‑146a controls the functional plasticity of gamma‑delta T cells N. Schmolka, T. Amado, B. Silva‑Santos, Anita Gomes; Lisbon, Portugal WS.C.08.3 microRNA‑135b: the pivot of macrophage polarization balance Naths Grazia Sukubo, M. Pesant, M. Locati; Rozzano (MI), Italy

TUESDAY

WS.C.09.5 Lamellipodia and filopodia promote environmental exploration but are dispensable for locomotion of leukocytes A. Eichner, Alexander Leithner, J. Mueller, A. Reversat, M. Brown, J. Schwarz, J. Merrin, D.J. de Gorter, F. Schur, J. Bayerl, I. de Vries, S. Wieser, R. Hauschild, F.P. Lai, M. Moser, D. Kerjaschki, K. Rottner, J.V. Small, T.E. Stradal, M. Sixt; Klosterneuburg, Austria WS.C.09.6 Histone methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extra‑nuclear protein, talin L. Jia Tong, M. Gunawan, N. Venkatesan, J. Wong, H. Berger, S. Yamazak, A. Gingras, F. Ginhoux, I‑hsin Su; Singapore, Singapore

Chairpersons: Anita Gomes; Lisboa, Portugal Herbert Strobl; Graz, Austria

WS.C.08.4 Altered miR‑125a expression in monocytes contributes to dysregulated IL‑16 levels in SLE. Siobhan Smith, J. Ní Gabhann, E. McCarthy, G. Kearns, C. Jefferies; Dublin, Ireland WS.C.08.5 Tracking myeloid cell development using methylation patterns Ulrike Träger, G. Raddatz, R. Schulz, A. Breiling, M. Feuerer; Heidelberg, Germany WS.C.08.6 Histone deacetylase 2 couples Interleukin‑10 anti‑inflammatory activity with Interleukin‑8 transcriptional repression: implication for Chronic obstructive pulmonary disease patients Monica Castellucci, M. Rossato, N. Tamassia, S. Gasperini, B. Mariotti, M.A. Cassatella, F. Bazzoni; Verona, Italy

nnWS.C.09

WS.C.09.4 Calcineurin‑NFAT signaling control of the innate response Jan Fric, T. Zelante, A. Wong, A. Mencarelli, B. Lee, M. Poindinger, P. Ricciardi‑Castagnoli; Brno, Czech Republic

Innate Cell Signalling & Function

Hall N

08:30 – 09:45 Chairpersons: Pavel Kovarik; Vienna, Austria Elke Scandella; St. Gallen, Switzerland WS.C.09.1 DNAM‑1 expression marks an alternative program of NK cell maturation Ludovic Martinet, L. Ferrari De Andrade, C. Guillerey, J. Lee, N. Huntington, M.J. Smyth; Toulouse, France WS.C.09.2 NK cells in human glioma tumor control: evidence of a distinct immune microenvironment in tumor vs non tumor infiltrated brain Elena Ciaglia, M. Abate, F. Montella, V. Seneca, G. Di Nuzzo, S. Pisanti, C. Laezza, G. Torelli, G. Catapano, M. Bifulco; Fisciano, Italy

nnWS.C.10

Macrophages in Diseases

Hall F2 15:45 – 17:00

Chairpersons: Judith Allen; Edinburgh, United Kingdom Chiara Porta; Rozzano, Italy WS.C.10.1 Alveolar macrophages modulate innate immune responses to respiratory syncytial virus (RSV) infection through MAVS signalling and type I interferons M. Goritzka, S. Makris, F. Kausar, S. Akira, Cecilia Johansson; London, United Kingdom WS.C.10.2 Autophagy as a key regulator of parasite survival in macrophages and dendritic cells P. Crauwels, L. Roßmann, R. Bohn, L. Miller, Z. Waibler, C. van Kooten, Ger van Zandbergen; Langen, Germany WS.C.10.3 Modulation of monocytes by bioactive lipid anandamide in multiple sclerosis involve distinct Toll‑like receptors Valerio Chiurchiu, M. Cencioni, M. De Bardi, A. Leuti, D. Centonze, L. Battistini, M. Maccarrone; Rome, Italy WS.C.10.4 Modulation of influenza virus‑induced macrophage activation by decoy receptor 3 (DcR3) M. Huang, S. Chen, H. Wu, Y. Chen, T. Chou, Shie‑Liang Hsieh; Taipei, Taiwan WS.C.10.5 Efferocytosis of CD8 T cells induces parasite‑permissive M2 macrophages in mice infected with Trypanosoma cruzi M.C. Piccin, L.C. Guillermo, N.S. Vellozo, S.P. Marques, T.S. Rigoni, G.A. DosReis, Marcela F. Lopes; Rio de Janeiro, Brazil WS.C.10.6 Ly6C+ monocytes and neutrophils promote renal kidney injury in a mouse model of shiga toxin‑induced hemolytic uremic syndrome Judith M. Pohl, J. Volke, S. Thiebes, F. Kerstin, B.J. Pichler, D.R. Engel; Essen, Germany

WS.C.09.3 The innate immune sensor IFI16 moves along dsDNA to distinguish self from nonself. Sarah A. Stratmann, S. Morrone, J. Sohn, A.M. van Oijen; Groningen, Netherlands

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ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

TUESDAY, SEPT. 8, 2015 Track D Innate Lymphoid Cells

Hall G 15:45 – 17:00

Chairpersons: Chiara Romagnani; Berlin, Germany Marcel B. Teunissen; Amsterdam, Netherlands WS.C.11.1 Human RORgt+ CD34+ cells are lineage‑specified progenitors of group 3 RORgt+ innate lymphoid cells Elisa Montaldo, K. Juelke, C. Romagnani; Genova, Italy WS.C.11.2 Regulation of group 2 innate lymphoid cells in the lung Claudia U. Duerr, C.D. McCarthy, B.C. Mindt, J.H. Fritz; Montreal, Canada WS.C.11.3 Notch signaling controls innate lymphoid cells balance S. Chea, N. Serafini, S. Schmutz, O. Burlen‑defranoux, D. Guy‑Grand, A. Cumano, J. Di Santo, Rachel Golub; Paris, France WS.C.11.4 TGF‑β is required for the development of intestinal CD103+CD11b+ dendritic cells which control group 3 innate lymphoid cell homeostasis Yasmina Laouar; Ann Arbor, United States WS.C.11.5 Id2 expression in human thymic progenitor cells drives commitment of innate lymphoid cell development Maho Nagasawa, B. Blom, H. Spits; Amsterdam, Netherlands WS.C.11.6 PLZF expression maps the early stages of ILC1 lineage development Michael G. Constantinides, H. Gudjonson, B.D. McDonald, I.E. Ishizuka, P.A. Verhoef, A.R. Dinner, A. Bendelac; Bethesda, United States

TRACK D Symposia nnS.D.03

Antibody Therapeutics

Hall E 11:15 – 12:30

Chairpersons: Lucienne Chatenoud; Paris, France John McCafferty; Cambridge, United Kingdom S.D.03.1

From broadly neutralizing antibodies to a new mechanism of diversification Antonio Lanzavecchia; Bellinzona, Switzerland Treatment of Autoimmune disease with antibodies Falk Nimmerjahn; Erlangen, Germany

S.D.03.3

Antibody effector function‑modulation through glycosylation Roy Jefferis; Birmingham, United Kingdom

Cancer Immunotherapy

Hall E 17:45 -19:00

Chairpersons: Christoph Zielinski; Vienna, Austria Paul Parren; Utrecht, Netherlands S.D.04.1

Making the most of CD137 (4‑1BB) in cancer immunotherapy Ignacio Melero; Pamplona, Spain

S.D.04.2

Cancer immunotherapy by PD‑1 blockade Tasuku Honjo; Kyoto, Japan

S.D.04.3

New concepts on cancer immunotherapy Laurence Zitvogel; Villejuif, France

www.eci-vienna2015.org

nnWS.D.05

T Cell Based Cancer Immunotherapy Hall F1 08:30 – 09:45

Chairpersons: Mirjam H.M. Heemskerk; Leiden, Netherlands Tim D. Sparwasser; Munich, Germany WS.D.05.1 PD‑1 expression conditions T‑cell avidity within an antigen‑specific repertoire Sylvain Simon, V. Vignard, L. Florenceau, B. Dréno, A. Khammari, F. Lang, N. Labarriere; Nantes, France WS.D.05.2 The microenvironment at the invasive margin between metastatic colorectal cancer tissue and adjacent liver represents a T cell trap and supports tumor survival ‑ an option for therapeutic intervention for metastatic colorectal cancer patients Christine S. Falk, N. Halama, I. Zörnig, A. Spille, C. Kahlert, C. Brandt, J. Krauss, T. Lerchl, M. Koch, N. Grabe, D. Jäger; Hannover, Germany WS.D.05.3 Adenosine receptor 2A blockade increases the efficacy of anti‑PD‑1 through enhanced anti‑tumor T cell responses Paul A. Beavis; Melbourne, Australia WS.D.05.4 T cell receptor sequencing indicates its potential use as predictive biomarker for dendritic cell‑based cancer immunotherapy in glioblastoma patients I. Sloma, S. Klingenbrunner, K. Fischhuber, R. Reitermaier, S. Efroni, T. Felzmann, Carmen Visus; Vienna, Austria WS.D.05.5 CAR T cells inflict sequential killing of multiple tumour target cells Alexander J. Davenport, M.R. Jenkins, R.S. Cross, C.S. Yong, D.S. Ritchie, J.A. Trapani, M.H. Kershaw, P.K. Darcy, P.J. Neeson; Melbourne, Australia WS.D.05.6 How do PI3K inhibitors affect the CD8 cytotoxic immune response? Ee Lyn Lim, D.R. Soond, K. Okkenhaug; Cambridge, United Kingdom

nnWS.D.06

Stem Cells and Cell-Based Therapy

Hall G

08:30 – 09:45 Chairpersons: Silke Appel; Bergen, Norway Idit Shachar; Rehovot, Israel

S.D.03.2

nnS.D.04

Workshops

WS.D.06.1 Pluripotent stem cells varying in a single antigen from recipients elicit upon transplantation cellular and humoral immune responses that can mediate graft rejection Sebastian Monecke, C. Hamann, L. Elsner, J. Nolte, W. Engel, G. Hasenfuß, A. Mansouri, K. Guan, R. Dressel; Göttingen, Germany WS.D.06.2 Human induced pluripotent stem cells are targets for allogeneic and autologous natural killer (NK) cells and killing is partly mediated by the activating NK receptor DNAM‑1 Carina Hamann, V. Kruse, S. Monecke, L. Cyganek, L. Elsner, D. Hübscher, L. Walter, K. Streckfuss‑Bömeke, K. Guan, R. Dressel; Göttingen, Germany WS.D.06.3 Modulation of microglia responses via mesenchymal stromal cells derived‑ microvesicles Yarúa Jaimes, Y. Naaldijk, K. Wenk, F. Emmrich; Leipzig, Germany

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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TUESDAY

nnWS.C.11

Program per Day

TUESDAY, SEPT. 8, 2015 Track E WS.D.06.4 Mesenchymal stem cells modulate experimental arthritis by inducing an early regulatory adaptive T response M. Lopez‑Santalla, P. Mancheño‑Corvo, R. Menta, J. Lopez‑Belmonte, O. DelaRosa, W. Dalemans, E. Lombardo, J.A. Bueren, Marina Garin; Madrid, Spain

WS.D.08.3 The involvement of the homing receptors CCR7 and CD62L in the pathogenesis of graft‑versus‑host disease Federico Herrera, V. Gomez Garcia De Soria, I. Portero Sainz, C. Fernandez Arandojo, A. Marcos Jimenez, A. Kreutzman, C. Muñoz Calleja; Madrid, Spain

WS.D.06.5 alloCELL: established procedure for donor selection and GMP‑compliant manufacturing of cellular products for therapeutic purpose S. Tischer, C. Priesner, L. Arseniev, J. Martens, L. Goudeva, H. Heuft, M. Hallersleben, C. Figueiredo, S. Immenschuh, U. Köhl, R. Blasczyk, B. Maecker‑Kolhoff, Bitta Eiz‑Vesper; Hannover, Germany

WS.D.08.4 In vitro‑generated myeloid‑derived suppressor cells (MDSCs) prevent murine graft‑versus‑host disease (GVHD) by inducing type 2 T cells without disabling anti‑tumor cytotoxicity J.J. Messmann, T. Reisser, F. Leithäuser, S. Muche, M. Lutz, K. Debatin, Gudrun Strauss; Ulm, Germany

WS.D.06.6 Isolation of antigen‑specific TCRs for immunotherapy using an MHC cell library and next generation sequencing Felix K. Lorenz, C. Ellinger, E. Kieback, S. Wilde, D.J. Schendel, W. Uckert; Berlin, Germany

nnWS.D.07

Novel Approaches for Vaccines

Hall F1

15:45 – 17:00 Chairpersons: África González‑Fernández; Vigo, Spain Richard Lo‑Man; Paris, France

TUESDAY

WS.D.07.1 Polyethylenimine‑based polyplex delivery of self‑replicating RNA vaccines Thomas Démoulins, P. Milona, P. Englezou, R. Suter, C. Pichon, N. Ruggli, K.C. McCullough; Mittelhäusern, Switzerland WS.D.07.2 Novel combined antigen M2e‑NP‑HAs is a potential candidate for research and development of universal influenza vaccines Wenling Wang, B. Huang, X. Wang, Y. Deng, W. Tan, L. Ruan; Beijing, China WS.D.07.3 Selected TLR agonists improve vaccination outcome in nicotine exposed mice Mahyar Nouri‑Shirazi, M. Zeng, B. Bible, S. Tamjidi; Boca Raton, United States WS.D.07.4 Nanoparticulation of a STING pathway ligand, cyclic di‑GMP, enhances cancer immunotherapy against metastatic melanoma Takashi Nakamura, H. Miyabe, M. Hyodo, Y. Sato, Y. Hayakawa, H. Harashima; Sapporo, Japan

WS.D.08.5 IL‑6 dysregulation and graft‑versus‑host disease: A new therapeutic target Antiopi Varelias, G.A. Kennedy, S. Vuckovic, L. Le Texier, P. Zhang, K.H. Gartlan, G. Thomas, G. Boyle, N. Cloonan, S.D. Olver, R.D. Kuns, M. Koyama, J. Leach, E. Sturgeon, J. Avery, P. Reddy, G.A. Yanik, A.D. Clouston, K.P. MacDonald, B.R. Blazar, K.R. Cooke, S. Tey, G.R. Hill; Brisbane, Australia WS.D.08.6 Interplay between donor PD‑L1 and recipient PD‑1 regulates acute graft rejection after liver transplantation X. Shi, S. Mancham, B. Hansen, J. de Jonge, L.J. van der Laan, F. Rivadeneira, H.J. Metselaar, Jaap Kwekkeboom; Rotterdam, Netherlands

TRACK E Workshop nnWS.E.01

Structural Biology and Imaging

Hall M 08:30 – 09:45

Chairpersons: Walter Keller; Graz, Austria Hans Brandstetter; Salzburg, Austria WS.E.01.1 An emerging approach for parallel quantification of intracellular protozoan parasites and host cell characterization using TissueFAXS cytometry M. Schmid, B. Dufner, J. Dürk, J. Dürk, R. Ecker, Uwe Ritter; Regensburg, Germany

WS.D.07.5 Dectin‑1 activation unlocks IL12A expression and reveals the Th1 potency of neonatal dendritic cells S. Lemoine, B. Jaron, S. Tabka, L. Majlessi, P. Tissieres, C. Leclerc, Richard Lo‑Man; Paris, France

WS.E.01.2 A bioinformatic framework for immune repertoire diversity profiling enables detection of immunological status Victor Greiff, P. Bhat, S. Cook, U. Menzel, W. Kang, S.T. Reddy; Basel, Switzerland

WS.D.07.6 Mucosal vaccination strategies against Mycobacterium tuberculosis infection Carolina Perdomo, A. Vogelzang, A. Kupz, S.H. Kaufmann; Berlin, Germany

WS.E.01.3 Visualization of T cell dynamics in the liver by multispectral optoacoustic tomography (MSOT) Michael J. Dudek; Munich, Germany

nnWS.D.08

Solid Organ and Bone Marrow Transplantation

Hall N 15:45 – 17:00

Chairpersons: Michel Braun; Gosselies, Belgium Gianpietro Semenzato; Padua, Italy WS.D.08.1 Xenotransplantation combined with bio‑signatures ‑ a milestone towards personalized medicine Michaela Prchal‑Murphy, S. Fajmann, A. Schumich, V. Sexl, M.N. Dworzak; Vienna, Austria WS.D.08.2 Human monocyte‑derived suppressor cells as an innovative immunotherapy for graft‑versus‑host disease Nona Janikashvili, M. Samson, A. Gautheron, M. Trad, M. Thébault, M. Ciudad, S. Audia, B. Bonnotte; Dijon, France 72

WS.E.01.4 A new reporter system for dissecting the interplay between pathogen physiology and the immune system by intravital 2‑photon imaging P. Formaglio, S. Heyde, R. Olekhnovitch, P. Bousso, Andreas J. Müller; Magdeburg, Germany WS.E.01.5 A chimeric protein derived from the major birch pollen allergen Bet v 1 and its homolog Api g 1 exhibits a domain‑swapped dimeric arrangement and a fold distinct from its parent structures Judith Wortmann, B. Gepp, H. Breiteneder, W. Keller; Graz, Austria WS.E.01.6 Mechanism of antibody recognition of neuronal intrinsically disordered protein tau O Cehlar, R. Skrabana, M. Novak; Bratislava, Slovakia

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

TUESDAY, SEPT. 8, 2015 Joint-Symposia of the Day JOINT-SYMPOSIA OF THE DAY Vaccine Development can Benefit from Computational Biology (jointly with IUIS) Hall A 14:00 – 15:30

Women in Immunology nnWO.00

Chairpersons: Jorge Kalil; São Paulo, Brazil Ursula Wiedermann; Vienna, Austria

Informal lunch event for members of the German Society for Immunology (DGfI), organized by the ,,Commission on Equality and Career Support“. Meet senior immunologists and talk about challenges and solutions in balancing career and family.

Systems biology analysis of influenza vaccines Bali Pulendran; Atlanta, United States

JS.04.2

Tuberculosis Vaccines and Biomarkers Stefan H.E. Kaufmann; Berlin, Germany

JS.04.3

Future approaches towards malaria vaccination I. Bujila, Marita Troye‑Blomberg, M. Cherif, G.S. Sanou, A. Lennartsson, I. Nebié, A. Östlund Farrants; Stockholm, Sweden

T Helper Cell Subsets in Health and Disease (jointly with EAACI)

Hall E

14:00 – 15:30 Chairpersons: Carsten Schmidt‑Weber; Munich, Germany Barbara Bohle; Vienna, Austria JS.05.1

Free Lunch bags will be provided. Fully booked, registration is no more possible!

BUSINESS AND ANCILLARY MEETINGS nnBA.16

JS.05.3

Th2 cells regulate epithelial immunity Carsten Schmidt‑Weber; Munich, Germany

nnBA.18

German Society for Immunology (DGfI)

Hall F2

Chairpersons: Rene Van Lier; Amsterdam, Netherlands Andreas Radbruch; Berlin, Germany JS.06.1

Towards 40‑color flow cytometry Pratip Chattopadhyay; Elkridge, United States

JS.06.2

T cell landscapes Tim Mosmann; Rochester, United States

nnBA.20

T cell therapies Dirk Busch; Munich, Germany

closed*

14:00 – 15:30 Chairpersons: Peter Openshaw; London, United Kingdom Verena Niederberger; Vienna, Austria

French Society of Immunology (SFI)

Belgian Immunological Society (BIS) Meeting Room 6 (2.12) 09:45 – 11:15

IUIS Quality Assessment and Standardization Committee Meeting

closed* L7 10:00 – 12:00

nnBA.21

EEIG ECI-EFIS Meeting Meeting Room 1 (1.85-86) 12:15 – 13:45 EFIS General Assembly

closed* nnBA.22

Meeting Room 5 (2.17) 14:00 – 17:00 Inaugural IUIS Vaccine Committee Meeting

closed*

Meeting Room 1 (1.85-86) 16:00 -17:30

JS.07.1

Impact of intestinal microbiota in shaping innate immunity Kathy McCoy; Bern, Switzerland

JS.07.2

The role of the transcription factor T‑bet in gut mucosal responses Graham M. Lord; London, United Kingdom

closed*

JS.07.3

Role of the microbiota in regulation of immunity in the respiratory tract Ben Marsland; Epalinges, Switzerland

* on invitation only

www.eci-vienna2015.org

Meeting Room 5 (2.17) 09:45 – 11:45

General Assembly (open to members of the respective society only) nnBA.19.1

The Mucosal Microbiome in Health and Disease (jointly with SMI) Hall G

Meeting Room 3 (2.15) 09:45 – 11:15

Annual board meeting (open to members of the respective society only) nnBA.19

Cytometry of the 21st Century (jointly with ISAC)

14:00 – 15:30

nnJS.07

Meeting Room 1 (1.85-86) 09:45 – 11:15

(open to members of the respective society only)

Retention of effector T cells in inflamed tissues Valerie Julia, D. Dombrowicz, D. Staumont‑Sallé; IPMC‑ Valbonne, France

JS.06.3

Scandinavian Society for Immunology (SSI)

General Assembly (open to members of the respective society only) nnBA.17

Stability of human Th17 cells in chronic inflammatory disorders Francesco Annunziato; Florence, Italy

JS.05.2

nnJS.06

L7 14:00 – 15:30

JS.04.1

nnJS.05

Career Lunch for Early Career Immunologists

nnBA.23

EFIS Board Meeting Meeting Room 5 (2.17) 17:00 -18:00

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

73

TUESDAY

nnJS.04

OTHER SESSIONS AND MEETINGS

Program per Day

TUESDAY, SEPT. 8, 2015 Meet the Professor Breakfast MEET THE PROFESSOR BREAKFAST Informal breakfast event for early career scientists. The “Meet the Professor Sessions” will provide participants the opportunity to meet the most renowned senior scientists in an interactive and casual manner. Small breakfast will be provided. Registration is possible via email and onsite at a first-come-first-serve basis. Maximum amount of participants: 30

nnME.02

Jürgen Wienands

Meeting Room 1 (1.85-86)



07:15 – 08:15

nnME.03

Ron Germain

Meeting Room 3 (2.15)

Luke O’Neill

nnP.B.24

Mediators of (Neuro) Immune Regulation

nnP.B.25

Allergen Specific Immune Response - Part 2

nnP.B.26

Allergic Disorders - Part 2

nnP.B.27

Tumor Immunity - Part 2

nnP.B.28

Tumormarkers

Track C – Innate Immunity

NK and NKT Cells - Part 2

nnP.C.11

Macrophages - Part 1

07:15 – 08:15

nnP.C.12

Macrophages - Part 2

Meeting Room 6 (2.12)

nnP.C.13

Dendritic Cell Biology - Part 2

07:15 – 08:15

nnP.C.14

Pattern Recognition Receptors - Part 2

nnP.C.15

Cytokines - Part 1

nnP.C.16

Cell Signaling - Part 2



TUESDAY

Animal Models of Autoimmunity

nnP.C.10

Meeting Room 5 (2.17)

nnME.05

nnP.B.23

Innate Immunity - Inflammation - Part 1

07:15 – 08:15 Nadine Cerf-Bensussan

(Chronic) Inflammatory Joint Disease - Part 2

nnP.C.09

nnME.04

nnP.B.22

POSTERS OF THE DAY ACCORDING TO TRACKS A, B, C, D, E

Track D – Disease Intervention Track A – Adaptive Immunity nnP.A.11

Lymphocyte Development - Part 1

nnP.A.12

Antigen Receptor Signalling

nnP.A.13

Antigen Processing and Presentation - Part 2

nnP.A.14

Th1 and Th2 Cells - Part 2

nnP.A.15

Regulatory T Cells - Part 2

nnP.A.16

Regulatory T Cells - Part 3

nnP.A.17

CD8+ T Cells - Part 2

nnP.A.18

Germinal Centre Reaction - Part 2

nnP.A.19

Antibody Engineering and B Cell Effector Molecules

Track B – Diseases nnP.B.15

Immunity to Virus Infection - Part 1

nnP.B.16

Immunity to Bacterial Infection and Parasites

nnP.B.17

Immunity to Parasite Infection

nnP.B.18

Primary Immunodeficiencies - Part 2

nnP.B.19

Diseases - Inflammation - Part 2

nnP.B.20

Inflammatory Bowel Disease

nnP.B.21

Neuroimmunology and Multiple Sclerosis

74

nnP.D.11

Vaccines - Part 2

nnP.D.12

Vaccines & Veterinary Immunology - Part 2

nnP.D.13

Immune Interventions in Autoimmunity - Part 2

nnP.D.14

Cancer Immunotherapy - Part 2

nnP.D.15

Cancer Immunotherapy - Part 3

nnP.D.16

Immunotherapy for Infectious Diseases

nnP.D.17

Biomarkers of Human Immune Responses & Immunogenicity against Biopharmaceuticals - Part 2

nnP.D.18

Immunopharmacology

Track E – Other nnP.E.02

Immune Response in Aging & Systems Biology - Part 1

nnP.E.03

Metabolism & Immunity

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

WEDNESDAY Schedule at a Glance Wednesday. . . . . . . . . . . . . . . . . . . . . 76 Keynote Lecture of the Day . . . . . . . . . . . . . . . . . . . . . . . . . . . 78 Overview per Track. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78 Track A . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 Track B . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81 Track C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84 Track D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 Track E . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 Joint-Symposia of the Day. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 WEDNESDAY

Other Sessions and Meetings. . . . . . . . . . . . . . . . . . . . . . . . . . . 88 Educational Courses & Scientific Satellite Symposia . . . . . . . 88 Business and Ancillary Meetings. . . . . . . . . . . . . . . . . . . . . . . . 88 Meet the Professor Breakfast. . . . . . . . . . . . . . . . . . . . . . . . . . . 88 Posters of the Day according to Tracks A, B, C, D, E . . . . . . . 89 Closing and Award Ceremony. . . . . . . . . . . . . . . . . . . . . . . . . 89 Related Post Congressional Events in Vienna after the 4th ECI Congress. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

75

Program per Day

WEDNESDAY, SEPT. 9, 2015 SCHEDULE AT A GLANCE WEDNESDAY

Wednesday, Sept. 9, 2015 Room

Hall A

Hall E

Hall F1

Hall F2

Hall G

Hall K

Level

2

0

0

0

-2

-2

07:15 – 08:15 08:15 – 08:30 08:30 – 08:45 08:45 – 09:00

S.A.05

Adaptive Immunity

09:00 – 09:15 Maintenance 09:15 – 09:30 09:30 – 09:45

of Lymphocyte Memory

S.B.05

Diseases Autoimmunity

WS.D.09

WS.C.12 Cancer Dendritic Cell Immunotherapy and Differentiation and Anti-Tumor Vaccines Function

WS.D.10

WS.C.13

Intervention and Therapy of Allergy

Mast Cells

09:45 – 10:00 10:00 – 10:15

EP.01

1st EFIS President's Symposium 10:30 – 10:45 On NK Cells and NK Cell-Based Therapy 10:45 – 11:00 of Leukemias 10:15 – 10:30

Poster Session and Guided Poster Walks / Coffee Break

11:00 – 11:15 11:15 – 11:30 11:30 – 11:45

S.C.05

Innate Immunity

11:45 – 12:00 Innate Lymphocytes 12:00 – 12:15 - Backstage or 12:15 – 12:30

Centerstage

S.D.05

Disease Intervention T Cell Mediated Immunotherapy

WS.A.12

Molecular & Cellular Control of CD8+ T Cells (part 3)

WS.B.14

WS.B.15 Immune Recognition Immune Regulation and Control of at the Intestinal Infections Barrier

WS.B.16

Mediators of Airway Inflammation

12:30 – 12:45 12:45 – 13:00 13:00 – 13:15 13:15 – 13:30

JS.08

KL.D.1

World Allergy Association (WAO) Mechanisms in Allergy

Disease Intervention 13:30 – 13:45 Cancer Therapy 13:45 – 14:00 14:00 – 14:15

JS.09

European Society for Immunodeficiencies (ESID) Newborn Screening for Immunodeficiency

14:15 – 14:30 14:30 – 14:45 14:45 – 15:00

WEDNESDAY

15:00 – 15:15

S.A.06

Adaptive Immunity 15:15 – 15:30 Molecular Switches 15:30 – 15:45 in Adaptive Immunity 15:45 – 16:00

S.B.06

Diseases Stroma - Immune Interactions in Cancer and Inflammation

WS.D.12

Immune Intervention in Autoimmune Diseases

WS.C.15

WS.A.15

WS.D.13

WS.A.16

WS.B.19

WS.B.20

Dendritic Cell Subsets

Treg Function / Biology

Immunotherapy of Infectious Diseases

16:00 – 16:15 16:15 – 16:30 16:30 – 16:45

S.C.06

16:45 – 17:00 Innate Immunity

S.D.06

Disease Intervention Inhibitory and Aging and the 17:00 – 17:15 Activating Receptors Immune System

WS.B.18

Tumor Biology and Immunosurveillance

Looking at the "States and Fates of T Cells"

Immune Modulation by Infectious Agents

HIV Infection and Immune Control

17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 18:00 – 18:15 18:15 – 18:30

Closing and Award Ceremony

18:30 – 18:45 18:45 – 19:00 19:00 – 19:15 19:15 – 19:30 19:30 – 19:45 19:45 – 20:00 20:00 – 20:15 20:15 – 20:30 20:30 – 20:45 20:45 – 21:00 21:00 – 21:15 21:15 – 21:30

76

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

WEDNESDAY, SEPT. 9, 2015 SCHEDULE AT A GLANCE WEDNESDAY

Wednesday, Sept. 9, 2015 Hall M

Hall N

Meeting Room 1 (1.85-86)

1

1

1

Meeting Room 2 (1.61)

Room

1

Level

ME.06

Mirjam Heemskerk

07:15 – 08:15 08:15 – 08:30 08:30 – 08:45

WS.C.14

NK and NKT Cell Function

08:45 – 09:00

WS.D.11

Imaging & cancer therapy

09:00 – 09:15 09:15 – 09:30 09:30 – 09:45 09:45 – 10:00 10:00 – 10:15

Poster Session and Guided Poster Walks / Coffee Break

10:15 – 10:30 10:30 – 10:45 10:45 – 11:00 11:00 – 11:15 11:15 – 11:30

WS.A.13

Lymphocyte Subsets (part 2)

WS.A.14

T Cell Mediated Control of GC Reactions

11:30 – 11:45

Scientific Satellite Meeting IUIS The Importance of Standardization for Immunology

WO.01

11:45 – 12:00 12:00 – 12:15 12:15 – 12:30 12:30 – 12:45 12:45 – 13:00 13:00 – 13:15 13:15 – 13:30

Women in Immunology She is a genius

13:30 – 13:45 13:45 – 14:00 14:00 – 14:15 14:15 – 14:30 14:30 – 14:45 14:45 – 15:00

Metabolism & Immunity

15:00 – 15:15

WS.B.17

WEDNESDAY

WS.E.02

15:15 – 15:30

Immune Dysregulation

15:30 – 15:45 15:45 – 16:00 16:00 – 16:15

WS.A.17

Extrinsic and Intrinsic Control of Positive/ Negative T Cell Selection

WS.A.18

Germinal Centers: Survival & Differentiation Signals

BA.23.1

Österreichische Gesellschaft für Allergologie und Immunologie (ÖGAI) Board Meeting (Vorstandssitzung)

16:15 – 16:30 16:30 – 16:45 16:45 – 17:00 17:00 – 17:15 17:15 – 17:30 17:30 – 17:45 17:45 – 18:00 18:00 – 18:15 18:15 – 18:30 18:30 – 18:45 18:45 – 19:00 19:00 – 19:15

BA.24

Österreichische Gesellschaft für Allergologie und Immunologie (ÖGAI) General Assembly (Generalversammlung)

19:15 – 19:30 19:30 – 19:45 19:45 – 20:00 20:00 – 20:15 20:15 – 20:30 20:30 – 20:45 20:45 – 21:00 21:00 – 21:15 21:15 – 21:30

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

77

Program per Day

WEDNESDAY, SEPT. 9, 2015 OVERVIEW PER TRACK

Keynote Lecture of the Day - KL.D.1 – Disease Intervention 13:00 – 14:00 Chairperson:

Hall A Anne Hosmalin; Paris, France

Cancer Therapy Michael Milone University of Pennsylvania, Department of Pathology & Laboralory Medicine; Philadelphia, United States Dr. Milone received his M.D. and Ph.D. in experimental pathology in 1999 from Rutgers-New Jersey Medical School (formerly the University of Medicine and Dentistry of New Jersey). After an Internship in Internal Medicine at the Hospital of the University of Pennsylvania, he completed post-graduate medical training in Clinical Pathology, Transfusion Medicine and Laboratory Toxicology. Following clinical training, Dr. Milone pursued post-doctoral research training in cancer immunology and adoptive immunotherapy with Dr. Carl June at the University of Pennsylvania where he performed basic research to develop CTL019, a genetically modified T cell therapy for B-cell leukemia and lymphoma that has been licensed by Novartis and undergoing early phase clinical testing. He is currently an Assistant Professor of Pathology and Laboratory Medicine at the University of Pennsylvania School of Medicine. At present, Dr. Milone’s laboratory is focused on T cell biology and the development of new techniques for culturing and genetically modifying T lymphocytes for adoptive immunotherapy of cancer.

OVERVIEW PER TRACK

WEDNESDAY

TRACK A – ADAPTIVE IMMUNITY

TRACK C – INNATE IMMUNITY

Symposia S.A.05 Maintenance of Lymphocyte Memory S.A.06 Molecular Switches in Adaptive Immunity

Symposia S.C.05 Innate Lymphocytes - Backstage or Centerstage S.C.06 Inhibitory and Activating Receptors

Workshops WS.A.12 WS.A.13 WS.A.14 WS.A.15 WS.A.16 WS.A.17

Workshops WS.C.12 WS.C.13 WS.C.14 WS.C.15

WS.A.18

Molecular & Cellular Control of CD8+ T Cells - Part 3 Lymphocyte subsets - Part 2 T Cell Mediated Control of GC Reactions Treg Function / Biology Looking at the "States and Fates of T Cells" Extrinsic and Intrinsic Control of Positive/Negative T Cell Selection Germinal Centers: Survival & Differentiation Signals

TRACK B – DISEASES Symposia S.B.05 Autoimmunity S.B.06 Stroma - Immune Interactions in Cancer and Inflammation Workshops WS.B.14 WS.B.15 WS.B.16 WS.B.17 WS.B.18 WS.B.19 WS.B.20

78

Immune Recognition and Control of Infections Immune Regulation at the Intestinal Barrier Mediators of Airway Inflammation Immune Dysregulation Tumor Biology and Immunosurveillance Immune Modulation by Infectious Agents HIV Infection and Immune Control

Dendritic Cell Differentiation and Function Mast Cells NK and NKT Cell Function Dendritic Cell Subsets

TRACK D – DISEASE INTERVENTION Symposia S.D.05 T Cell Mediated Immunotherapy S.D.06 Aging and the Immune System Workshops WS.D.09 WS.D.10 WS.D.11 WS.D.12 WS.D.13

Cancer Immunotherapy and Anti-Tumor Vaccines Intervention and Therapy of Allergy Imaging & Cancer Therapy Immune Intervention in Autoimmune Disease Immunotherapy of Infectious Diseases

TRACK E – OTHER Workshop WS.E.02 Metabolism & Immunity

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

WEDNESDAY, SEPT. 9, 2015 Track A TRACK A

WS.A.12.4 MicroRNA‑155 overexpression augments acute anti‑viral and anti‑tumor CD8+ T cell responses Jennifer L. Hope, E. Stelekati, A. Fike, C. Stairiker, D.T. Gracias, A.J. Carey, J.A. Fraietta, Y.M. Mueller, P.D. Katsikis; Rotterdam, Netherlands

Symposia Maintenance of Lymphocyte Memory Hall A 08:30 – 09:45 Chairpersons: Hans‑Martin Jäck; Erlangen, Germany Matteo Iannacone; Milan, Italy S.A.05.1

Shortterm versus Longterm Memory Andreas Radbruch, C. Cendon, A. Okhrimenko, H. Chang, H. Mei, T. Dörner, R. Riedel, J. Dong; Berlin, Germany

S.A.05.2

A systemic B‑cell memory response in non‑immunized mice S. Le Gallou, R. Fritzen, J. Weill, Claude‑Agnès Reynaud; Paris, France

S.A.05.3

Hall A

Chairpersons: Michael L. Dustin; New York, United States Hannes Stockinger; Vienna, Austria S.A.06.1

The PI3K signalling switch in adaptive immunity: don’t forget to turn it off! Klaus Okkenhaug; Cambridge, United Kingdom

S.A.06.2

Molecular switches in memory B cell formation Jürgen Wienands; Göttingen, Germany

S.A.06.3

T cell signaling threshold switches and cancer therapeutic implications N. Hermann‑Kleiter, V. Klepsch, Gottfried Baier; Innsbruck, Austria

WS.A.13.1 Establishment of a novel mouse model to study IL‑7‑driven immune deviation in vivo Maria Schreiber, A. Hommel, K. Anastassiadis, E. Bonifacio, K. Kretschmer; Dresden, Germany WS.A.13.2 CD28 expression is required after T cell priming for helper T cell responses and protective immunity to infection Michelle A. Linterman, A.E. Denton, D. Diverkar, S. Clare, G. Dougan, M. Espeli, K.G. Smith; Cambridge, United Kingdom WS.A.13.3 Direct and indirect induction of T helper cell differentiation by Notch Christina Helbig, D. Amsen; Amsterdam, Netherlands WS.A.13.4 Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive Foxp3high regulatory T cells in humans M. Miyara, N. Warner, R. Kannagi, S. Sakaguchi, Guy Gorochov; Paris, France

Workshops Hall F1 11:15 – 12:30 Chairpersons: Shinya Sakaguchi; Vienna, Austria Klaas van Gisbergen; Amsterdam, Netherlands WS.A.12.1 Therapeutic deletion of IL‑17 producing CD8+ T cells (Tc17) attenuates graft‑versus‑host disease without impairing anti‑leukemic immunity Kate H. Gartlan, K.A. Markey, A. Varelias, M. Bunting, M. Koyama, K. Lineburg, G. Boyle, M. Cheong, S. Lane, S. Olver, N. Raffelt, R. Kuns, B. Teal, K. MacDonald, G.R. Hill; Brisbane, Australia WS.A.12.2 ADAP and SKAP55 regulate PD‑1 expression in CD8+ cytotoxic T lymphocytes and the efficacy of anti‑tumor immunotherapy C. Li, W. Li, J. Xiao, Q. Leng, C.E. Rudd, BIN WEI, H. Wang; Wuhan, China WS.A.12.3 Non‑lytic degranulation of cytotoxic T lymphocytes as a mechanism of immune regulation Anna Kabanova, M. Bocchia, C.T. Baldari; Siena, Italy

www.eci-vienna2015.org

Hall M 11:15 – 12:30

14:45 – 16:00

Molecular & Cellular Control of CD8+ T Cells - Part 3

Lymphocyte Subsets - Part 2

Chairpersons: Christophe Paget; Lille, France Winfried Pickl; Vienna, Austria

Molecular Switches in Adaptive Immunity

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WS.A.12.6 The immune adaptor ADAP regulates reciprocal TGF‑beta1‑integrin crosstalk to protect from influenza virus infection C. Li, S. Jiao, G. Wang, Y. Gao, C. Liu, X. He, B. Wei, B. Wei, H. Chen, Hongyan Wang; Shanghai, China

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Interdependence of B and T cell memory David Gray; Edinburgh, United Kindom

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WS.A.12.5 Interferon‑γ regulates CD8+ memory T cell differentiation and survival in response to weak but not strong TCR signals D. Stoycheva, Thomas Schüler; Magdeburg, Germany

WEDNESDAY

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WS.A.13.5 A critical neutrophil‑γδT cell axis in host response to respiratory bacterial infection M. Hassane, J. Fontaine, E. Patin, R. Porte, I. Prinz, B. Ryffel, J. Sirard, C. Faveeuw, F. Trottein, Christophe Paget; Lille, France WS.A.13.6 How many TCR clonotypes does a body maintain? Grant Lythe, C. Molina Paris, R. Callard, R. Hoare; Leeds, United Kingdom

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T Cell Mediated Control of GC Reactions

Hall N 11:15 – 12:30

Chairpersons: Denis Thieffry; Paris, France Michelle A. Linterman; Cambridge, United Kingdom WS.A.14.1 T follicular helper cell‑independent generation of bone marrow‑resident resting memory T helper cells Shintaro Hojyo, J. Sarkander, K. Tokoyoda; Berlin, Germany WS.A.14.2 Distinct T helper cell dependence of memory B cell proliferation versus plasma cell differentiation Franziska Zabel, A. Fettelschoss, P. Johansen, T.M. Kündig, M.F. Bachmann; Schlieren/Zurich, Switzerland

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Program per Day

WEDNESDAY, SEPT. 9, 2015 Track A WS.A.14.3 TSLP‑activated dendritic cells induce T follicular helper cell differentiation through OX40‑ligand Coline Trichot, L. Pattarini, S. Bogiatzi, M. Grandclaudon, M. Durand, T. Hori, V. Soumelis; Paris, France WS.A.14.4 Uncovering the mechanism of IL‑21 signalling in the germinal centre response to T‑dependent antigen Christoph Jandl, S.M. Liu, C. Loetsch, J. Warren, C. King; Darlinghurst, Australia WS.A.14.5 ICOS maintains the T follicular helper cell phenotype by downregulating Krüppel‑like factor 2 Annette Lahmann, J.P. Weber, F. Fuhrmann, R.K. Feist, M.S. Al Baz, L. Gentz, D. Vu Van, H.W. Mages, C. Haftmann, R. Riedel, W. Schuh, R.A. Kroczek, A. Radbruch, M. Mashregi, A. Hutloff; Berlin, Germany WS.A.14.6 Follicular regulatory T cells control humoral autoimmunity when NFAT2 overcomes Blimp1‑mediated CXCR5 suppression M. Vaeth, A. Koenig, G. Müller, D. Stauss, L. Dietz, S. Klein‑Hessling, E. Serfling, M. Lipp, I. Berberich, Friederike Berberich‑Siebelt; Wuerzburg, Germany

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Treg Function / Biology

Hall G 14:45 – 16:00

Chairpersons: Iris K. Gratz; Salzburg, Austria Friederike Berberich‑Siebelt; Wuerzburg, Germany WS.A.15.1 Deciphering the epigenetic and transcription‑factor based control of the Foxp3 gene promoter Michael Delacher, M.M. Barra, A. Kazakov, D. Kägebein, A. Breiling, K. Eichelbaum, Y. Herzig, M. Czeh, F. Rosenbauer, F. Lyko, J. Krijgsveld, J. Abramson, M. Feuerer; Heidelberg, Germany

WEDNESDAY

WS.A.15.2 Enhanced Foxo‑1 and Foxp3 mRNA expression in poly(ADP‑ribose)polymerase‑1 (PARP‑1) deficient mice F. Novelli, Claudio Pioli; Rome, Italy WS.A.15.3 Role of NF‑kB in the biology of FoxP3+ regulatory T cells at steady state and during inflammation Emilie Ronin, A. Rouers, C. Pouchy, S. Grégoire, B. Zaragoza, A. Burlion, F. Weih, A. Baeyens, B. Salomon; Paris, France WS.A.15.4 An unexpected inhibitory role of a Parkinson’s disease gene DJ‑1 in CD4+ regulatory T Cells E. Danileviciute, M. Gillespie, R. Balling, Feng Q. He; Esch‑sur‑Alzette, Luxembourg WS.A.15.5 Activation of TGF‑beta by integrin alpha v beta 8 is essential for effector regulatory T‑cell‑mediated suppression of T‑cell‑mediated inflammation J.J. Worthington, A. Kelly, C. Smedley, D. Bauché, S. Campbell, J. Marie, Mark Travis; Manchester, United Kingdom WS.A.15.6 In vivo TNFR2‑mediated expansion of host regulatory T cells to protect from acute graft‑versus‑host disease Andreas Beilhack, M. Chopra, M. Biehl, A. Brandl, J. Amich, M. Vaeth, J. Findeis, R. Holtappels, J. Podlech, A. Mottok, S. Kraus, A. Jordán Garrote, C. Bäuerlein, E. Ribechini, A. Fick, A. Seher, J. Polz, S. Krappmann, H. Einsele, T.D. Müller, M. Reddehase, M.B. Lutz, D.N. Männel, F. Berberich‑Siebelt, H. Wajant; Wuerzburg, Germany

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Looking at the “States and Fates of T Cells”

Hall F2 16:15 – 17:30

Chairpersons: Johannes Huppa; Vienna, Austria Maria L. Toribio; Madrid, Spain WS.A.16.1 Label‑free identification of T cell subpopulations Maria Danner, V.C. Hirschfeld‑Warneken, J.P. Spatz; Heidelberg, Germany WS.A.16.2 Intravital imaging of physical interactions between regulatory and effector T‑cells in a murine retrovirus model Lucas Otto, M. Gunzer, K. Dietze, U. Dittmer; Essen, Germany WS.A.16.3 Synchronizing transcriptional control of T cell metabolism, differentiation and function K. Man, A. Vasanthakumar, Axel Kallies; Parkville, Australia WS.A.16.4 The soluble cytoplasmic tail of CD45 (ct‑CD45) is an inhibitory factor in human serum and induces an anergy‑like state in T cells Alexander Puck, M. Seyerl, S. Hopf, R. Aigner, P. Cejka, O. Majdic, S. Blüml, E. Thell, G. Zlabinger, J. Leitner, P. Steinberger, J. Stöckl; Vienna, Austria WS.A.16.5 The contained self‑reactive peripheral T cell repertoire: size, diversity and cellular composition David M. Richards, E. Ruggiero, A. Hofer, J.P. Sefrin, M. Schmidt, C. von Kalle, M. Feuerer; Heidelberg, Germany WS.A.16.6 THEMIS controls the fate of beneficial and pathogenic self‑reactive T cells Leen Baudewijn, F. Lambolez, R. Spiering, K. Kakugawa, H. Cheroutre; La Jolla, United States

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Extrinsic and Intrinsic Control of Positive/ Negative T Cell Selection Hall M 16:15 – 17:30

Chairpersons: Ludger Klein; Munich, Germany Wilfried Ellmeier; Vienna, Austria WS.A.17.1 Identifying and tracking autoimmune‑inducing T cell clones in Aire‑/‑Cblb‑/‑ mice Mandeep Singh, C. Teh, A. Enders, C. Goodnow; Canberra, Australia WS.A.17.2 Mice with thymic epithelial von Hippel‑Lindau deletion are lacking a functional thymus A. Hollenbeck, S. Weber, M. Necke, K. Händschke, K. Dietze, U. Dittmer, K.S. Lang, J.W. Fischer, B. Opalka, U. Dührsen, Joachim R. Göthert; Essen, Germany WS.A.17.3 Aire‑dependent transcripts have shortened 3’UTRs and show greater stability by evading microRNA‑mediated repression. Clotilde Guyon, N. Jmari, Y. Li, J. Denoyel, N. Fujikado, C. Blanchet, D. Root, M. Giraud; Paris, France WS.A.17.4 Characterization of a unique model of APECED‑like Aire deficient rat with strong auto‑immune symptoms Jason Ossart, S. Menoret, E. Autrusseau, C. Usal, A. Moreau, F. Hubert, I. Anegon, R. Josien, C. Guillonneau; Nantes, France

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

WEDNESDAY, SEPT. 9, 2015 Track B

WS.A.17.6 RRas2 (TC21) sets the threshold for negative selection in the thymus Ana Martínez‑Riaño, B. Alarcón; Madrid, Spain

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Germinal Centers: Survival & Differentiation Signals

Hall N 16:15 – 17:30

Chairpersons: Rushad Pavri; Vienna, Austria Simon Fillatreau; Berlin, Germany WS.A.18.1 A novel role for CD248 in controlling the differentiation of follicular dendritic cells (FDCs) following immune challenge Nathalie Steinthal, S. Nayar, A.J. Naylor, G.E. Desanti, J.L. Marshall, Y. Zhang, K.M. Toellner, J.H. Caamaño, D.R. Withers, C.D. Buckley, F. Barone; Birmingham, United Kingdom WS.A.18.2 FAS inactivation releases rogue Germinal Center B cells that escape antigen control and drive IgE and autoantibody production Danyal Butt, T. Chan, K. Bourne, J. Hermes, L. O’Reilly, A. Strasser, S. Tangye, T. Phan, V. Rao, R. Brink; Sydney, Australia WS.A.18.3 RRas2 plays a fundamental non‑redundant role in germinal center formation by activating the PI3K and non‑canonical NFkB pathways in B cells Pilar Mendoza, N. Martínez‑Martín, B. Cubelos, X.R. Bustelo, T. Kurosaki, B. Alarcón; Madrid, Spain WS.A.18.4 Antigen‑affinity mediates B cell survival through differential BAFF receptor signaling via the PI3K/Mcl‑1 cascade Felix M. Wensveen, A. Kater, R. Brink, E. Eldering; Amsterdam, Netherlands WS.A.18.5 Treatment with tofacitinib inhibits human naïve B lymphocyte development and function Jens D. Thiel, K. Fischer, R.E. Voll, R. Lorenzetti, N. Venhoff, M. Rizzi; Freiburg, Germany WS.A.18.6 IL‑35‑producing B cells regulate immunity during autoimmune and infectious diseases Ping Shen, T. Roch, E. Hilgenberg, S. Ries, V. Dang, I. Sakwa, S.M. Anderton, S. Fillatreau; Berlin, Germany

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Autoimmunity

Hall E 08:30 – 09:45

Chairpersons: Reinhold Schmidt; Hannover, Germany Marie Wahren‑Herlenius; Stockholm, Sweden S.B.05.1

Rheumatoid athritis Reinhold Schmidt; Hannover, Germany

S.B.05.2

T cell responses against neurons Roland Liblau; Toulouse, France

S.B.05.3

Behcet’s Disease: From autoimmunity to autoinflammation Ahmet Gül; Istanbul, Turkey

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Stroma - Immune Interactions in Cancer and Inflammation

Hall E 14:45 – 16:00

Chairpersons: Wlodzimierz Maslinski; Warsaw, Poland Catherine Sautès‑Fridman; Paris, France S.B.06.1

Stromal immune cell interaction Jasper Koning; Amsterdam, Netherlands

S.B.06.2

The interplay between L‑arginine metabolism and adoptive immunity in cancer Vincenzo Bronte; Verona, Italy

S.B.06.3

Immune sensing of fat tissue Bojan Polic; Rijeka, Croatia

Workshops nnWS.B.14

Immune Recognition and Control of Infections

Hall F2 11:15 – 12:30

Chairpersons: Michael Lohoff; Marburg, Germany Anca Dorhoi; Berlin, Germany WS.B.14.1 Autoimmune associated gene Ptpn22 negatively regulates Dectin‑1 signalling in dendritic cells and controls the development of pathogenic IL‑17+IFNy+ CD4+ T‑cells Harriet A. Purvis, F. Clarke, C. Sanchez Blanco, R. Zamoyska, G.H. Cornish, A.P. Cope; London, United Kingdom WS.B.14.2 Role of CD64+CX3CR1+ mononuclear phagocytes during Helicobacter pylori infection Barbara Kronsteiner‑Dobramysl, M. Viladomiu, J. Bassaganya‑Riera, C. Phillipson, R. Hontecillas; Blacksburg, United States WS.B.14.3 Lung‑residing myeloid‑derived suppressor cells control susceptibility to disease in murine pulmonary tuberculosis J. Knaul, L. Scheuermann, V. Brinkmann, H. Mollenkopf, V. Yeremeev, S.H. Kaufmann, Anca Dorhoi; Berlin, Germany

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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WEDNESDAY

WS.A.17.5 T cell receptor upregulation creates a feedback loop during negative selection R. Sapkota, S. Hemmers, B. Polic, O. Gorka, R. Mejias‑Luque, M. Gerhard, J. Ruland, K. Rajewsky, A. Waisman, B. Becher, Thorsten Buch; Zurich, Switzerland

Program per Day

WEDNESDAY, SEPT. 9, 2015 Track B WS.B.14.4 Chronic lung inflammation enhances humoral immunity to Streptococcus pneumonia via the pIgR/ sIg axis Andreas Jeron, J. Boehme, S. Stegemann‑Koniszewski, J. Wissing, L. Jänsch, D. Bruder, Infection Immunology Group; Magdeburg, Germany WS.B.14.5 EphA2 promotes the development of experimental cerebral malaria T.P. King, P.N. Mimche, C.F. Bray, L.M. Brady, M. Galinski, Tracey J. Lamb; Atlanta, United States WS.B.14.6 Enhancement of pathogen‑specific natural killer cell ‘memory’ by removal of a viral innate immune signalling inhibitor Hongwei Ren, C.T. Benfield, R.P. Sumner, B.J. Ferguson, C. Huber, F. Colucci, G.L. Smith; Cambridge, United Kingdom

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Immune Regulation at the Intestinal Barrier

Hall G 11:15 – 12:30

Chairpersons: Maria Rescigno; Milan, Italy Helena Tlaskalova‑Hogenova, Prague, Czech Republic WS.B.15.1 Impact of microbiota on intestinal immune cell composition and intestinal barrier function Franziska Schmidt, T. Kruis, A. Batra, G. Loh, M. Schumann, A.A. Kühl, M. Blaut, B. Siegmund; Berlin, Germany

WEDNESDAY

WS.B.15.2 Microbes isolated from inflammatory bowel disease patients disrupt the gut epithelial barrier Adela Dusilova, J. Malkova, M. Hornova, H. Tlaskalova‑Hogenova, M. Kverka; Prague, Czech Republic WS.B.15.3 The effect of long‑term probiotic intervention in fast‑aging Ercc1‑/Δ7 mice Adriaan A. van Beek, B. Sovran, F. Hugenholtz, M. Boekschoten, P. de Vos, J.M. Wells, J.J. Hoeijmakers, P.J. Leenen, R.W. Hendriks, H.F. Savelkoul; Wageningen, Netherlands WS.B.15.4 Plasmacytoid and conventional cDC1 DCs in the secretory IgA response towards rotavirus Katharina Lahl, A. Sen, N. Feng, H. Greenberg, E. Butcher; Frederiksberg, Denmark WS.B.15.5 TGF‑β signaling in ILC3 prevents spontaneous microbiota‑induced colorectal cancer D. Bauché, I. Treilleux, M. Veldhoen, Julien C. Marie; Lyon, France WS.B.15.6 The crucial role of the transcription factor GATA‑3 in the development of TH2‑cell mediated ulcerative colitis Vanessa Popp, I. Ho, B. Weigmann; Erlangen, Germany

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Mediators of Airway Inflammation

Hall K

11:15 – 12:30 Chairpersons: Ronald van Ree; Amsterdam, Netherlands Peter Openshaw; London, United Kingdom WS.B.16.1 RelB‑deficient dendritic cells promote the development of spontaneous allergic airway inflammation in mice P.M. Nair, Malcolm R. Starkey, T.J. Haw, R. Ruscher, M.R. Maradana, R. Thomas, B. O’Sullivan, P.M. Hansbro; New Lambton Heights, Australia

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WS.B.16.2 The dual role of Leukotriene A4 hydrolase in allergic airway disease Dhiren F. Patel, S. Akthar, T. Peiró, S.A. Walker, L.G. Gregory, C.M. Lloyd, R.J. Snelgrove; London, United Kingdom WS.B.16.3 The danger receptor FPR2 controls the initiation of allergic immune responses Ursula Smole, J. Phelan, N. Yao, Z. Lijie, S. Lajoie, M. Wills‑Karp; Baltimore, United States WS.B.16.4 IFN‑γ‑STAT1‑IRF1‑axis restricts IL‑9 in Th9 cells by opposing IRF4 functions and is dysregulated in asthma Lucia Campos Carrascosa, M. Klein, C. Lückel, L. Thomas, S. Hagner‑Benes, A. König, D. Riedel, T. Decker, A. Bock, M. Lohoff, H. Garn, B. Schaub, F. Berberich‑Siebelt, T. Bopp, M. Huber; Marburg, Germany WS.B.16.5 IFN‑γ and IL‑17A drive distinct airway changes in a murine model of steroid‑unresponsive severe asthma Mahesh Raundhal, C. Morse, A. Khare, T.B. Oriss, J. Kolls, S. Wenzel, A. Ray, P. Ray; Pittsburgh, United States WS.B.16.6 Compound A modulates steroid insensitive chemokines in airway smooth muscle cells via IRF‑1 dependent and independent pathways Adelina Gavrila, L. Chachi, O. Tliba, Y. Amrani, C. Brightling; Leicester, United Kingdom

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Immune Dysregulation

Hall N 14:45 – 16:00

Chairpersons: Hendrik Poeck; Munich, Germany Ludovic Martinet; Toulouse, France WS.B.17.1 Ultraviolet light converts propranolol, a non‑selective β‑blocker and potential lupus‑inducing drug, into a pro‑inflammatory AhR ligand K. Dorgham, A. Mathian, Z. Amoura, Hans Yssel, G. Gorochov; Paris, France WS.B.17.2 Modulatory capacities of soluble Fc‑epsilon RI in the IgE‑mediated immune response Sherezade Moñino Romero, C. Bannert, K. Schmidthaler, T. Eiwegger, E. Dehlink, A. Fiocchi, A.S. Amoah, M. Yazdanbakhsh, B. Bohle, E. Fiebiger, Z. Szépfalusi; Vienna, Austria WS.B.17.3 RIG‑I‑induced type I IFNs promote regeneration of the intestinal stem cell compartment during acute tissue damage J.C. Fischer, M. Bscheider, G. Eisenkolb, C. Lin, A. Wintges, V. Otten, C. Lindemans, S. Heidegger, M. Rudelius, S. Monette, K.A. Porosnicu Rodriguez, S. Liebermann, C. Liu, S. Lienenklaus, U. Kalinke, J. Ruland, C. Peschel, M. Docampo, E. Velardi, R. Jenq, A.M. Hanash, J.A. Dudakov, T. Haas, M.R. van den Brink, Hendrik Poeck; Munich, Germany WS.B.17.4 Immunosurveillance and therapy of multiple myeloma is CD226‑dependent C. Guillerey, L. Ferrari de Andrade, S. Vuckovic, M. Chesi, L. Bergsagel, G.R. Hill, M.J. Smyth, Ludovic Martinet; Toulouse, France WS.B.17.5 NFATc1 proteins are critical survival factors in Burkitt lymphomagenesis K. Murti, H. Fender, R. Busch, V. Wild, E. Serfling, Andris Avots; Wuerzburg, Germany

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

WEDNESDAY, SEPT. 9, 2015 Track B

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Tumor Biology and Immunosurveillance

Hall F1 16:15 – 17:30

Chairpersons: Bojan Polic; Rijeka, Croatia Günes Esendağlı; Ankara, Turkey WS.B.18.1 Identification and characterization of putative neoplastic stem cells in human mast cell leukemia Gregor Eisenwort, B. Peter, I. Sadovnik, K. Blatt, G. Stefanzl, S. Cerny‑Reiterer, G. Hoermann, T. Rülicke, M. Willmann, M. Bilban, C. Mannhalter, J. Schwaab, W.R. Sperr, M. Arock, A. Reiter, P. Valent; Vienna, Austria WS.B.18.2 The telomeric protein TRF2 overexpression in cancer cells induces immune escape through MDSC recruitment and activation Julien Cherfils‑Vicini, L. Cervera, C. Iltis, F. Allain, A. Biroccio, E. Vivier, E. Gilson; Nice, France

WS.B.19.4 AP‑1 transcription factor serves as a molecular switch between Chlamydia pneumoniae replication and persistence S. Krämer, P. Crauwels, R. Bohn, C. Radzimski, M. Szaszák, M. Klinger, J. Rupp, Ger van Zandbergen; Langen, Germany WS.B.19.5 Helminths protect against autoimmunity through IL‑5 and IL‑33‑induced eosinophils Conor M. Finlay; Dublin, Ireland WS.B.19.6 Host genetic polymorphisms affect p24 Gag epitope presentation and T‑cell engagement in HIV‑1 infection Tracy M. Josephs, J.E. McLaren, K. Ladell, C. Geldmacher, J. Rossjohn, D.A. Price, S. Gras; Melbourne, Australia

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HIV Infection and Immune Control

Hall K

16:15 – 17:30 Chairpersons: Ana Sousa; Lisboa, Portugal Florence Niedergang; Paris, France

WS.B.18.3 Necroptotic effector molecules regulate tumor immunogenicity Yuting MA, H. YANG, G. Kroemer; Paris, France

WS.B.20.1 CD40L‑inducible tunneling nanotube networks facilitate HIV‑1 transmission to CD4+ T cells by pro‑inflammatory dendritic cells Colleen R. Zaccard, R.B. Mailliard, G. Rappocciolo, V. Ayyavoo, S.C. Watkins, C.R. Rinaldo; Pittsburgh, United States

WS.B.18.4 sCYLD expression causes B‑CLL development in mice and men M. Hahn, J. Bürckert, C. Pallasch, A. Waisman, T. Wunderlich, Nadine Hövelmeyer; Mainz, Germany

WS.B.20.2 HIV‑1 infection increases S1P‑R1 expression in the human thymus Rachel S. Resop, J.F. Craft, D.N. Vatakis, B. Blom, C.H. Uittenbogaart; Los Angeles, United States

WS.B.18.5 The effect of NF‑κB on tumour‑stromal interactions in colorectal cancer Grace A. O’Malley, P. Lohan, S. Rani, K. Lynch, S. Naicker, G. Shaw, T. Ritter, L.J. Egan, A.E. Ryan; Galway, Ireland

WS.B.20.3 Impaired clearance activity in HIV‑1 infected macrophages and development of opportunistic bacteria A. Dumas, G. Lê‑Bury, C. Deschamps, F. Herit, P. Bourdoncle, S. Benichou, D. Russell, M. Gordon, Florence Niedergang; Paris, France

WS.B.18.6 Effects of PKC412 and its metabolites CGP52421 and CGP62221 on proliferation of neoplastic mast cells and IgE‑mediated histamine release Barbara Peter, G.E. Winter, K. Blatt, U. Rix, K.L. Bennett, G. Stefanzl, E. Hadzijusufovic, C. Dutreix, J. Roesel, P.W. Manley, G. Superti‑Furga, P. Valent; Vienna, Austria

nnWS.B.19

Immune Modulation by Infectious Agents

Hall G 16:15 – 17:30

Chairpersons: Sebastian Lang; Essen, Germany Irma Schabussova; Vienna, Austria WS.B.19.1 Microbiota transfer to non‑obese diabetic mice ‑ impact of Akkermansia muciniphila on the delay of diabetes Arno Hänninen, R. Toivonen, C. Belzer, J. Ouwerkerk, S. Pietilä, R. Emani, A. Rintala, W.M. de Vos; Turku, Finland WS.B.19.2 Mechanisms of disease tolerance to gram‑negative sepsis Riem Gawish, B. Maier, K. Lakovits, A. Hladik, A. Korosec, M. Ildiko, F. Oakley, B. John, I. Lang, S. Knapp; Vienna, Austria

WS.B.20.4 Impairment of CCR6+ and CXCR3+ T‑helper cell migration in HIV‑1 infection is rescued by modulating actin polymerization Valentina Cecchinato, E. Bernasconi, R.F. Speck, M. Proietti, U. Sauermann, G. Danelon, T. Rezzonico Jost, F. Grassi, L. Raeli, F. Schöni‑Affolter, C. Stahl‑Hennig, M. Uguccioni, Swiss HIV Cohort Study (SHCS); Bellinzona, Switzerland WS.B.20.5 Sex‑dependent functional impact of TLR7 c.32A>T polymorphism on type I IFN‑production by plasmacytoid dendritic cells: implication in the susceptibility to HIV‑1 infection Pascal Azar, J. Méjia, C. Cénac, S. Laffont, M. Requena, M. Cazabat, R. Carcénac, J. Izopet, P. Delobel, J. Guéry, ANRS EP53 X‑LIBRIS Study Group; Toulouse, France WS.B.20.6 Central memory CD4 T cells gene expression signature in HIV infection shows G2/M arrest, but reduced apoptosis Gustavo Olvera‑García, T. Aguilar‑García, I. Imaz‑Rosshandler, C. Rangel‑Escareño, L. Orozco, J. Zúñiga, J. Vazquez‑Pérez, I. Aguilar‑Delfín, S. Pérez‑Patrigeon, E. Espinosa; Tlalpan, Mexico

WS.B.19.3 Lung resident memory CD4+ T cells (Trm) play a critical role in protective immunity to Bordetella pertussis Mieszko M. Wilk, R.M. McManus, A. Misiak, M.A. Lynch, K.H. Mills; Dublin, Ireland

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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WEDNESDAY

WS.B.17.6 Plasmacytoid dendritic cells promote HIV‑1‑induced group‑3 innate lymphoid cell depletion Zheng Zhang, J. Zhao, L. Cheng, F. Wang, L. Su; Beijing, China

Program per Day

WEDNESDAY, SEPT. 9, 2015 Track C TRACK C

WS.C.12.5 Innate‑to‑innate cell communication privileges mast cells with dendritic cell key features Jan Dudeck, A. Medyukhina, A. Hoppe, A. Karutz, M. Gerlach, C. Svensson, S. Speier, M. Figge, A. Dudeck; Dresden, Germany

Symposia nnS.C.05

Innate Lymphocytes Backstage or Centerstage

Hall A 11:15 – 12:30

Chairpersons: Bruno Silva‑Santos; Lisbon, Portugal Vladka Curin Šerbec; Ljubljana, Slovenia S.C.05.1

NK cells Lorenzo Moretta; Rome, Italy

nnWS.C.13

S.C.05.2

The Biology of Human ILC Populations Hergen Spits, J. Bernink, S. Bal, X. Romero; Amsterdam, Netherlands

Chairpersons: Massimo Triggiani; Salerno, Italy Peter Valent; Vienna, Austria

S.C.05.3

Gamma/Delta T cells Adrian Hayday; London, United Kingdom

nnS.C.06

Inhibitory and Activating Receptors

Hall A

16:15 – 17:30

S.C.06.1

Role of the CD94/NKG2C activating receptor in the adaptive-like human NK-cell response to cytomegalovirus Miguel Lopez Botet; Barcelona, Spain

S.C.06.2

Prevention of collateral damage by immune inhibitory receptors Linde Meyaard; Utrecht, Netherlands

S.C.06.3

Sensing intracellular nucleic acids Veith Hornung; Bonn, Germany

Workshops nnWS.C.12

Dendritic Cell Differentiation and Function

Hall F2 08:30 – 09:45

Chairpersons: Maria Carla Bosco; Genova, Italy Diana Dudziak; Erlangen, Germany WS.C.12.1 Lipid peroxidation causes antigen release from endosomes for cross‑presentation Ilse Dingjan, D.R. Verboogen, L.M. Paardekooper, L.J. Visser, G. Fisher von Mollard, S.S. Henriet, C.G. Figdor, M. ter Beest, G. van den Bogaart; Nijmegen, Netherlands WS.C.12.2 Regulation of IL‑6 secretion by dendritic cells Daniëlle Verboogen, M. ter Beest, G. van den Bogaart; Nijmegen, Netherlands WS.C.12.3 Modulation of dendritic cells function by dermal fibroblasts. Anna Malecka, Q. Wang, S. Shah, A. Saalbach, M.J. Gough, P.M. Patel, A.M. Jackson; Nottingham, United Kingdom WS.C.12.4 Estrogen receptor α expression in human plasmacytoid dendritic cells is required to promote optimal production of type I interferons and pro‑inflammatory cytokines in response to TLR‑7 stimulation Pascal Azar, S. Laffont, C. Cénac, J. Plumas, C. Aspord, J. Guéry; Toulouse, France

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Mast Cells

Hall G 08:30 – 09:45

Chairpersons: Stipan Jonjic; Rijeka, Croatia Gunnur Deniz; Istanbul, Turkey

WEDNESDAY

WS.C.12.6 MAPK‑activated kinase MK2 exerts immune regulatory functions in dendritic cells involving JAK1 signaling Klara Soukup, A. Halfmann, F. Poyer, E. Sahin, G. Schabbauer, T. Felzmann, A.M. Dohnal; Vienna, Austria

WS.C.13.1 The yin and yang function of IL‑33‑ST2 axis in murine mast cells: A systems immunological approach Peter Natesan Pushparaj, A. Chaudhary, A. Abuzenadah, M.H. Al‑Qahtani; Jeddah, Saudi Arabia WS.C.13.2 Real‑time imaging of mast cell interactions with Foxp3+ regulatory T cells and dendritic cells in skin inflammation R. Msallam, G. Gautier, U. Blank, B. Malissen, P. Launay, Jean Davoust; Paris, France WS.C.13.3 Mast cells rapidly control resident macrophage phagocytosis decreasing survival in severe sepsis Gregory Gautier, A. Dahdah, T. Attout, F. Fiore, E. Lebourdais, J. Davoust, U. blank, B. Malissen, P. Launay; Paris, France WS.C.13.4 Evaluation of effects of various targeted drugs on IgE receptor‑dependent signal transduction and activation of mast cells and basophils Dubravka Smiljkovic, K. Blatt, G. Wedeh, G. Stefanzl, M. Arock, P. Valent; Vienna, Austria WS.C.13.5 Role of IL‑17A and mast cells in intestinal reperfusion injury Mayya Geha, M. Tsokos, G. Tsokos; Boston, United States WS.C.13.6 Interleukin‑33 promotes the proliferation of mouse mast cells through ST2/MyD88 and p38 MAPK‑dependent and Kit‑independent pathways. Rohit Saluja, T. Hawro, J. Eberle, M.K. Church, M. Maurer; Bhopal, India

nnWS.C.14

NK and NKT Cell Function

Hall M 08:30 – 09:45

Chairpersons: Adelheid Cerwenka; Heidelberg, Germany Veronika Sexl; Vienna, Austria WS.C.14.1 iNKT cells control cancer progression by restraining pro‑angiogenic tumor infiltrating macrophages Filippo Cortesi, G. Delfanti, A. Calcinotto, F. Gorini, F. Pucci, M. Grioni, M. De Palma, M. Bellone, G. Casorati, P. Dellabona; Milan, Italy WS.C.14.2 Innate iNKT cell recognition of HIV‑1 infected dendritic cells is an early detection mechanism targeted by viral immune evasion D. Paquin‑Proulx, A. Gibbs, S. Bächle, A. Checa, A. Introini, E. Leeansyah, C.E. Wheelock, D.F. Nixon, K. Broliden, A. Tjernlund, M. Moll, Johan K. Sandberg; Stockholm, Sweden

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

WEDNESDAY, SEPT. 9, 2015 Track D

WS.C.14.4 Ex vivo generation of therapeutically relevant numbers of activated natural killers with potent anti tumor activity in vitro and in vivo Markus Granzin, M. Miller, M. Berg, R. Childs, V. Huppert, A. Cerwenka; Bergisch Gladbach, Germany WS.C.14.5 Decidual stromal cells display a strong inhibitory effect on NK cell function and dendritic cell differentiation. Daniele Croxatto, P. Vacca, F. Canegallo, R. Conte, P. Venturini, L. Moretta, M. Mingari; Genoa, Italy WS.C.14.6 Regulatory T cells suppress effector NK cell responses during an acute retroviral infection by consumption of IL‑2 Elisabeth Littwitz‑Salomon, U. Dittmer, K. Gibbert; Essen, Germany

nnWS.C.15

Dendritic Cell Subsets

Hall F2 14:45 – 16:00

Chairpersons: Muzlifah Haniffa; Newcastle, United Kingdom Martin Zenke; Aachen, Germany WS.C.15.1 CyTOF analysis reveals proinflammatory and antiinflammatory DC subsets in newborn blood with distinct reactivity to pathogens S. Lemoine, X. Zhang, A. Abbas, B. Beitz, M. Velpaux‑Lefevre, M. Burlandy, F. Porcheray, C. Leclerc, Richard Lo‑Man; Paris, France WS.C.15.2 PI3Kγ has a distinct and essential role in regulating lung‑specific dendritic cell development downstream of Flt3 Samuel P. Nobs, C. Schneider, M.G. Dietrich, T. Brocker, A. Rolink, E. Hirsch, M. Kopf; Zürich, Switzerland WS.C.15.3 IL‑12p40 and IL‑10 producing preCD8α/Clec9A+ dendritic cells are induced in neonates upon Listeria monocytogenes infection. Arnaud Köhler, D. Torres, S. Delbauve, I. Caminschi, M. Lahoud, K. Shortman, V. Flamand; Gosselies, Belgium WS.C.15.4 Specialization of human myeloid Dendritic Cells type 1 for extracellular pathogens Lukas Heger, G.F. Heidkamp, N. Eissing, A. Hartmann, K. Rogler, C. Alexiou, J. Zenk, B. Spriewald, A. Mackensen, G. Schuler, A. Purbojo, R. Cesnjevar, F. Nimmerjahn, D. Dudziak; Erlangen, Germany WS.C.15.5 Bone Morphogenic Protein 7 (BMP7) promotes in vitro generation of high numbers of inflammatory type Langerhans‑like dendritic cells Izabela Borek, R. Köffel, I. Fedorenko, N. Yasmin, C. Krump, H. Strobl; Graz, Austria WS.C.15.6 Identification of the triggering receptor expressed on myeloid cells‑1 (TREM‑1) as a novel regulator of Langerhans cells functions in a hypoxic environment F. Raggi, D. Pierobon, I. Cambieri, S. Occhipinti, P. Cappello, F. Novelli, T. Musso, C. Castagnoli, L. Varesio, M. Giovarelli, Maria Carla C. Bosco; Genova, Italy

www.eci-vienna2015.org

TRACK D Symposia nnS.D.05

T Cell Mediated Immunotherapy

Hall E

11:15 – 12:30 Chairpersons: Wilfried Ellmeier; Vienna, Austria Piotr Trzonkowski; Gdańsk, Poland S.D.05.1

When transgenes shape immunity Chiara Bonini; Milan, Italy

S.D.05.2

TCR engineered virus‑specific T cells for treatment of high risk leukemia Mirjam H.M. Heemskerk; Leiden, Netherlands

S.D.05.3

Regulatory T cells in allogeineic stem cell transplantation Matthias Edinger; Regensburg, Germany

nnS.D.06

Aging and the Immune System

Hall E 16:15 – 17:30

Chairpersons: Beatrix Grubeck‑Loebenstein; Innsbruck, Austria Rafael Solana; Cordoba, Spain S.D.06.1

Causes and Consequences of Cellular Immune Aging Victor Appay; Paris, France

S.D.06.2

The immune system from childhood to old age Martina Prelog; Würzburg, Germany

S.D.06.3

Functional immunosenescence of NK and T cells: relative impact of age and CMV infection. Rafael Solana, A. Pera, C. Campos, S. Cantisan, R. Tarazona; Cordoba, Spain

Workshops nnWS.D.09

Cancer Immunotherapy and Anti-Tumor Vaccines

Hall F1 08:30 – 09:45

Chairpersons: Stephan Wagner; Vienna, Austria Laurence Zitvogel; Villejuif, France WS.D.09.1 A novel systemically applied TLR‑agonist with potent anti‑tumoral effects Jutta Petschenka, F. Vascotto, K. Reuter, M. Vormehr, R. Roth, A. König, C. Worm, M. Brkic, N. Krause, U. Schmitt, M. Diken, S. Kreiter, S. Hamm, S. Strobl, Ö. Türeci, U. Sahin; Mainz, Germany WS.D.09.2 Glyco‑engineering of monoclonal antibodies enhances potential to promote adaptive immunity Aniekan Etuk, C. Klein, C. Gerdes, A. Passioukov, F. Farzaneh, L.D. Barber; London, United Kingdom WS.D.09.3 Virotherapy with a Semliki Forest virus‑based vector encoding IL‑12 synergizes with PD‑1/PD‑L1 blockade J.I. Quetglas, S. Labiano, M.Á. Aznar, E. Bolaños, A. Azpilicueta, I. Rodríguez, E. Casales, A.R. Sánchez‑Paulete, V. Segura, C. Smerdou, Ignacio Melero; Pamplona, Spain WS.D.09.4 Vdelta1 T cells expressing natural cytotoxicity receptors for adoptive cell therapy of leukemia D.V. Correia*, A. Almeida*, D.R. Anjos, Bruno Silva‑Santos; Lisbon, Portugal

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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WEDNESDAY

WS.C.14.3 Interleukin‑1 receptor 8 (IL‑1R8) plays a crucial role in Natural Killer (NK) cell differentiation and function Martina Molgora, E. Bonavita, A. Ponzetta, M. Barbagallo, G. Benigni, G. Bernardini, F. Riva, A. Santoni, A. Mantovani, C. Garlanda; Rozzano, Italy

Program per Day

WEDNESDAY, SEPT. 9, 2015 Track D WS.D.09.5 A TLR7 agonist enhances the anti‑tumour efficacy of obinutuzumab through an NK cell/CD4 dependent mechanism in murine lymphoma models Eleanor J. Cheadle, G. Lipowska‑Bhalla, C. Klein, S.J. Dovedi, J. Honeychurch, T.M. Illidge; Manchester, United Kingdom WS.D.09.6 Preclinical analysis of novel targeted therapies against Notch‑dependent human T‑ALL M. García‑Peydró, S. González‑García, M. Mosquera, Maria L. Toribio; Madrid, Spain

nnWS.D.10

Intervention and Therapy of Allergy

Hall K

08:30 – 09:45 Chairpersons: Peter Korosec; Golnik, Slovenia Barbara Bohle; Vienna, Austria WS.D.10.1 Melatonin supplement for children with atopic dermatitis and sleep disturbance ‑ A randomized, double‑blind, placebo‑controlled crossover study Yung‑Sen Chang, M. Lin, J. Lee, P. Lee, Y. Dai, K. Chu, C. Chen, K. Wan, B. Chiang; Taipei, Taiwan WS.D.10.2 Improved lung function and reduced asthmatic phenotype by adenoviral vaccines encoding for Dec‑targeted antigen Andre Maaske, T. Niezold, F. Devos, J. Vanoirbeek, M. Peters, M. Tenbusch; Bochum, Germany WS.D.10.3 Changes in markers associated with regulatory and pro‑allergic dendritic cell in peripheral blood correlate with clinical efficacy Laurent Mascarell, C. Gueguen, H. Moussu, J. Bouley, M. le Mignon, E. Nony, V. Bodo, P. Moingeon; Antony, France

WEDNESDAY

WS.D.10.4 Monitoring the epitope recognition profiles of IgE, IgG1 and IgG4 during birch pollen immunotherapy Barbara Gepp, N. Lengger, C. Möbs, W. Pfützner, C. Radauer, B. Bohle, H. Breiteneder; Vienna, Austria WS.D.10.5 Safety, dose finding and clinical effects of BM32, a recombinant B cell epitope‑based grass pollen vaccine, evaluated in the Vienna Challenge Chamber (VCC) in patients with grass pollen‑induced allergic Rhinitis Petra Zieglmayer, P. Lemell, R. Zieglmayer, F. Horak, A. Neubauer, R. Henning, R. Valenta; Vienna, Austria WS.D.10.6 Efficient IgE‑depletion by IgEnio, a novel IgE‑adsorber, shows beneficial effects on allergy symptoms Christian Lupinek, K. Derfler, S. Lee, T. Prikoszovich, O. Movadat, E. Wollmann, V. Petkov, V. Schoder, R. Cervenka, T. Plaichner, G. Stegfellner, H. Huber, R. Henning, J. Kozik‑Jaromin, A. Gauly, H. Leinenbach, I. Uhlenbusch‑Koerwer, R. Valenta; Vienna, Austria

nnWS.D.11

Imaging & Cancer Therapy

Hall N 08:30 – 09:45

Chairpersons: Patrizio Giacomini; Rome, Italy Jeanette Leusen; Utrecht, Netherlands WS.D.11.1 S100A8/A9 as an imaging target for in vivo visualisation of tumor‑mediated immune remodelling in pre‑metastatic tissue Fabian Flores‑Borja, M. Eisenblaetter, J.J. Lee, C. Wefers, H. Smith, R. Hueting, M. Cooper, P. Blower, T. Vogl, J. Roth, A. Tutt, T. Schaeffter, T. Ng; London, United Kingdom

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WS.D.11.2 Single molecule microscopy of T‑cell signaling components in live cells Florian Baumgart, A. Arnold, G. Schütz; Vienna, Austria WS.D.11.3 Interplay between chemokine driven actin flow and substrate adhesion in migratory T cells Miroslav Hons, V. Bierbaum, M. Foelser, J. Abe, T. Bollenbach, G. Schuetz, M. Sixt, J.V. Stein; Klosterneuburg, Austria WS.D.11.4 Sub‑apoptotic dosages of pro‑oxidant vitamin cocktails sensitize human melanoma cells to NK cell lysis E. Tremante, L. Santarelli, E. Lo Monaco, C. Sampaoli, T. Ingegnere, R. Guerrieri, M. Tomasetti, Patrizio Giacomini; Rome, Italy WS.D.11.5 Phase I and Phase II clinical trials of MVA‑EBNA1/ LMP2, a therapeutic cancer vaccine designed to treat Epstein‑Barr Virus (EBV) positive malignancies Graham S. Taylor, H. Jia, K. Harrington, L. Wai Lee, C. Roberts, A. Hartley, C. Edwards, L. McGuigan, E.P. Hui, A.T. Chan, A. Rickinson, N. Steven; Birmingham, United Kingdom WS.D.11.6 Improved in vivo anti‑tumor effects of IgA‑Her2 antibodies through half‑life extension and serum exposure enhancement by FcRn targeting Saskia Meyer, M. Nederend, J.H. Jansen, S.R. Jacobino, J. Meeldijk, N. Bovenschen, T. Valerius, R. Ubink, P. Boross, G. Rouwendal, J.H. Leusen; Utrecht, Netherlands

nnWS.D.12

Immune Intervention in Autoimmune Disease

Hall F1 14:45 – 16:00

Chairpersons: Thomas Wekerle; Vienna, Austria Gabriella Sármay; Budapest, Hungary WS.D.12.1 Inorganic‑organic hybrid nanoparticles in the treatment of CNS autoimmune responses with glucocorticoids Elena Montes Cobos, S. Ring, J. Heck, C. Feldmann, F. Lühder, H.M. Reichardt; Göttingen, Germany WS.D.12.2 A vascular targeting IL‑4 immunocytokine synergizes with dexamethasone to support tolerogenic macrophages and expand functional regulatory T cells in a murine model of arthritis Joanna Z. Kawalkowska, T. Hemmerle, F. Doll, F. Pretto, M. Matasci, D. Neri, R.O. Williams; Oxford, United Kingdom WS.D.12.3 Selective depletion of citrullinated protein specific B cells in rheumatoid arthritis by an auto‑epitope peptide and a killing peptide coupled together to the surface of biodegradable nanobeads Judit Pozsgay, A. Magyar, G. Gyulai, F. Babos, K. Uray, B. Rojkovich, F. Hudecz, G. Nagy, É. Kiss, G. Sármay; Budapest, Hungary WS.D.12.4 IL‑35 maintains regulatory T cells phenotype to suppress autoimmune disease Kailash Singh, J. Lindroos, E. Kadesjö, M. Hjört, M. Lundberg, D. Espes, P. Carlsson, S. Sandler, L. Thorvaldsson; Uppsala, Sweden WS.D.12.5 Selective suppression of autoreactive B and T cells by chimeric molecules in a humanized mouse model of Autoimmune Diabetes Iliyan Manoylov, N. Delcheva, I. Atanassova, A. Tchorbanov; Sofia, Bulgaria

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

Program per Day

WEDNESDAY, SEPT. 9, 2015 Track E

nnWS.D.13

Immunotherapy of Infectious Diseases

Hall K 14:45 – 16:00

Chairpersons: Sylvia Knapp; Vienna, Austria Jacek Rolinski; Lublin, Poland WS.D.13.1 Activation of circulating platelets lead to the release of potent antiviral IgG A. Assinger, A. Tuiskunen Bäck, A. Luik, M. Salzmann, S. Badrnya, J. Kral, W. Schrottmeier, M. Karlsson, M N. Forsell; Stockholm, Sweden WS.D.13.2 Evaluation of a novel passive immunotherapy approach targeting HMGB1 in the treatment of sepsis Natalie E. Stevens, C.K. Fraser, M.J. Chapman, T.R. Kuchel, K.R. Diener, J.D. Hayball; Adelaide, Australia WS.D.13.3 Identification of novel CD8+ T‑cell epitopes from the human adenovirus to improve immunomonitoring and recruitment of antiviral T cells for adoptive immunotherapy Sabine Tischer, C. Bunse, J. Lahrberg, J. Kwoczek, A. Heim, R. Geyeregger, R. Blasczyk, B. Maecker‑Kolhoff, B. Eiz‑Vesper; Hannover, Germany

TRACK E Workshop nnWS.E.02

Metabolism & Immunity

Hall M 14:45 – 16:00

Chairpersons: Klaus G. Schmetterer; Vienna, Austria Valery Chereshnev; Perm, Russian Federation WS.E.02.1 Superoxide dismutase 1 protects from type I interferon‑driven oxidative damage in viral hepatitis Anannya Bhattacharya, A.N. Hegazy, N. Deigendesch, L. Kosack, J. Cupovic, R.K. Kandasamy, A. Hildebrandt, D. Merkler, A.A. Kühl, B. Vilagos, C. Schliehe, I. Panse, K. Khamina, H. Baazim, I. Arnold, L. Flatz, H.C. Xu, P.A. Lang, A. Aderem, A. Takaoka, G. Superti‑Furga, J. Colinge, B. Ludewig, M. Löhning , A. Bergthaler; Vienna, Austria WS.E.02.2 Metabolic requirements for γδ cell development Stefania Martin, N. Sumaria, D.J. Pennington; London, United Kingdom WS.E.02.3 Immunological recognition of dietary proteins are required for intestinal development and barrier function S. Hartmann, A. Visekruna, H. Mollenkopf, K. Rajalingam, Ulrich Steinhoff; Marburg, Germany

WS.D.13.4 Adoptive T cell therapy for treatment of chronic hepatitis B Nina Böttinger, K. Wisskirchen, P. Knolle, U. Protzer; Munich, Germany

WS.E.02.4 Macrophages rearrange the mitochondrial electron transport chain upon sensing live bacteria J. Garaude, R. Acín‑Pérez, S. Martínez‑Cano, M. Ugolini, E. Nistal‑Villán, S. Hervás‑Stubbs, L.E. Sander, J.A. Enríquez, David Sancho; Madrid, Spain

WS.D.13.5 G‑CSF directly affects CD8+ cytotoxic T‑cell characteristics resulting in impaired T cell functionality in hematopoietic stem cell donors Carola E. Bunse, S. Tischer, J. Lahrberg, J. Kwoczek, M. Oelke, C. Figueiredo, S. Thomas, R. Blasczyk, B. Eiz‑Vesper; Hannover, Germany

WS.E.02.5 Placental heme oxigenase 1 expression promotes immune adaptation to pregnancy and fetal growth in mice Maria E. Solano, M.K. Kowal, G.E. O’Rourke, R. Barikbin, K. Karimi, P.C. Arck; Hamburg, Germany

WS.D.13.6 First‑in‑man treatment with polypeptide generated adenovirus‑specific T cell lines René Geyeregger, C. Freimueller, J. Stemberger, M. Artwohl, V. Witt, T. Lion, G. Fischer, A. Lawitschka, J. Ritter, M. Hummel, W. Holter, G. Fritsch, S. Matthes‑Leodolter; Vienna, Austria

WS.E.02.6 Immunometabolic phenotype of prototypical Th1‑ and Th2‑type mouse strains Nada Pejnovic, N. Jovicic, I. Jeftic, I. Jovanovic, G. Radosavljevic, N. Arsenijevic, M.L. Lukic; Kragujevac, Serbia

JOINT-SYMPOSIA OF THE DAY nnJS.08

Mechanisms in Allergy (jointly with WAO)

Hall F1 12:45 – 14:15

Chairpersons: Ruby Pawankar; Tokyo, Japan Rudolf Valenta; Vienna, Austria

www.eci-vienna2015.org

JS.08.1

The epithelium as a key regulator of barrier defense and immune regulation in allergic airway disease Ruby Pawankar; Tokyo, Japan

JS.08.2

Innate immunity and Omics in allergy Lanny Rosenwasser; Kansas City, United States

JS.08.3

The role of oxidative stress in allergic sensitization Ronald van Ree; Amsterdam, Netherlands

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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WEDNESDAY

WS.D.12.6 Antigen‑specific T cell deletion by erythrocyte‑targeted antigens: memory of tolerance and induction of regulatory T cells Alizée J. Grimm, J.A. Hubbell; Lausanne, Switzerland

Program per Day

WEDNESDAY, SEPT. 9, 2015 Other Sessions and Meetings nnJS.09

EDUCATIONAL COURSES & SCIENTIFIC SATELLITE SYMPOSIA

Newborn Screening for Immunodeficiency (jointly with ESID) Hall F2 12:45 – 14:15

Chairpersons: Bobby Gaspar; London, United Kingdom Elisabeth Förster‑Waldl; Vienna, Austria JS.09.1

nnIUIS - The Importance of Standardization for Immunology Attendance is free of charge – no registration required!

NBS for SCID ‑ Why is it so important Bobby Gaspar; London, United Kingdom

JS.09.2

NBS for primary immunodeficiencies ‑ not only SCID Stephan Borte; Stockholm, Sweden

JS.09.3

The European experience with NBS for SCID so far Marie Audrain; Nantes, France

On NK Cells and NK Cell-Based Therapy of Leukemias

Hall A 09:45 – 11:15

Chairpersons: Lorenzo Moretta; Rome, Italy Franco Locatelli; Rome, Italy EP.01.1

Features of CMV‑induced memory‑like human NK cells Alessandro Moretta; Genoa, Italy

EP.01.2

On Innate Lymphoid cell signature, plasticity and redundancy Eric Vivier, S. Ugolini; Marseille, France

EP.01.3

The role of NK cells in T‑cell depleted haploidentical stem cell transplantation in pediatric patients Franco Locatelli; Rome, Italy

WEDNESDAY

Manipulation of the innate and adaptive immune response to improve the outcome of allogeneic stem cell transplantation Hermann Einsele; Wuerzburg, Germany

Women in Immunology nnWO.01

She is a Genius

Hall M 12:45 – 14:15

Chairpersons: Anna Fogdell‑Hahn; Stockholm, Sweden Sylvia Cohen Kaminsky; Paris, France WO.01.1

Historical perspective of active exclusion from academy to where we are today Agnes Wold; Gothenburg, Sweden

WO.01.2

A gut feeling from a woman immunologist Nadine Cerf‑Bensussan; Paris, France

WO.01.3

10:45 – 11:15 Current developments in complement analysis and international quality assessment Michael Kirschfink; Heidelberg, Germany

11:45 – 12:15 International Standardization in Autoantibody Testing Luis Andrade; São Paulo, Brasil

EFIS President’s Symposium

EP.01.4

Chairpersons: Rudolf Valenta; Vienna, Austria Michael Kirschfink; Heidelberg, Germany

11:15 – 11:45 Challenges in monoclonal antibody standardization Pablo Engel; Barcelona, Spain

OTHER SESSIONS AND MEETINGS

nnEP.01

Meeting Room 1 (1.85) 10:45 – 14:30

Why have we missed the female genius? Fabrice Papillon; Paris, France

12:15 – 12:45 Approaches for detection and quantification of multiple allergens in allergen extracts Stefan Vieths; Langen, Germany 12:45 – 14:30 Get together for discussion and networking

BUSINESS AND ANCILLARY MEETINGS nnBA.23.1

Austrian Society for Allergology und Immunology (ÖGAI)

Board Meeting (Vorstandssitzung) closed* nnBA.24

Meeting Room 1 (1.85) 16:15 – 17:30

Austrian Society for Allergology und Immunology (ÖGAI)

General Assembly (Generalversammlung) (open to members of the respective society only)

Meeting Room 1 (1.85) 19:15 – 20:45

* on invitation only

MEET THE PROFESSOR BREAKFAST 07:15 – 08:15 Informal breakfast event for early career scientists. The “Meet the Professor Sessions” will provide participants the opportunity to meet the most renowned scientists in an interactive and casual manner. Small breakfast will be provided. Registration is possible via email and onsite at a first-come-first-serve basis. Maximum amount of participants: 30

nnME.06

Mirjam Heemskerk



88

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

Meeting Room 2 (1.61) 07:15 – 08:15

www.eci-vienna2015.org

Program per Day

WEDNESDAY, SEPT. 9, 2015 Posters of the Day according to Tracks A, B, C, D, E POSTERS OF THE DAY ACCORDING TO TRACKS A, B, C, D, E

Track C – Innate Immunity nnP.C.17

Innate Immunity - Inflammation - Part 2

nnP.C.18

NK and NKT Cells - Part 3

Track A – Adaptive Immunity

nnP.C.19

Macrophages - Part 3

nnP.A.20

Dynamics of T Cell Activation and Contraction - Part 1

nnP.C.20

Dendritic Cell Biology - Part 3

nnP.A.21

Lymphocyte Development - Part 2

nnP.C.21

Pattern Recognition Receptors - Part 3

nnP.A.22

Antigen Processing and Presentation - Part 3

nnP.C.22

Complement and Fc Receptors

nnP.A.23

Costimulatory Pathways in Immunity and Tolerance

nnP.C.23

Cytokines - Part 2

nnP.C.24

microRNAs and Epigenetics

nnP.A.24

Th17 Cells - Part 2

nnP.A.25

Regulatory T Cells - Part 4

nnP.A.26

CD8+ T Cells - Part 3

nnP.D.19

Vaccines for Infectious Diseases

nnP.A.27

Germinal Centre Reaction - Part 3

nnP.D.20

Vaccine Adjuvants

nnP.A.28

Dynamics of T cell activation and contraction - Part 2

nnP.D.21

Intervention & Therapy of Allergy - Part 2

nnP.D.22

Cancer Immunotherapy - Part 4

nnP.D.23

Stem Cells & Cell Based Therapies - Part 2

nnP.D.24

Biomarkers of Human Immune Responses & Immunogenicity against Biopharmaceuticals - Part 3

nnP.D.25

Organ Transplantation

nnP.D.26

Immunosuppressive and Tolerogenic Treatment

nnP.D.27

MHC and other Gene Polymorphisms in Health & Disease

nnP.B.29

Immunity to Virus Infection - Part 2

nnP.B.30

Primary Immunodeficiencies - Part 3

nnP.B.31

Secondary Immunodeficiencies

nnP.B.32

Diseases - Inflammation - Part 3

nnP.B.33

Environmental and Genetic Factors in Autoimmunity

nnP.B.34

Multiple Sclerosis

nnP.B.35

Immune Regulation at Barrier Sites - Part 1

nnP.B.36

Immune Regulation at Barrier Sites - Part 2

nnP.B.37

Cytokines in Regulation of Disease

nnP.B.38

Allergen Specific Immune Response - Part 3

nnP.B.39

Tumor Immunity - Part 3

nnP.B.40

Myelo-and Lymphoproliferative Disorders

nnP.B.41

Atherosclerosis and Cardiovascular Diseases

nnP.B.42

Immunity to Virus Infection - Part 3

WEDNESDAY

Track B – Diseases

Track D – Disease Intervention

Track E – Other nnP.E.04

Immune Response in Aging & Systems Biology - Part 2

nnP.E.05

Reproductive Immunology

CLOSING AND AWARD CEREMONY 17:45 – 18:45

Hall A

EFIS-Biolegend Bright Sparks Awards Hannes Stockinger, EFIS treasurer Gene Lay, CEO Biolegend Poster Awards Barbara Bohle, President Scientific Program Committee 4th ECI ECI 2018 Gunnur Deniz, President 5th ECI Closing Words Winfried F. Pickl, President 4th ECI

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Program per Day

RELATED POST CONGRESSIONAL EVENTS IN VIENNA AFTER THE 4TH ECI EDUCATIONAL COURSES & SCIENTIFIC SATELLITE SYMPOSIA

WEDNESDAY

September 10, 2015 2nd TRAINING FOR TRAINERS - International Network of Universities for Molecular Allergology and Immunology Medical University of Vienna, Jugendstilhörsaal, Spitalgasse 23, 1090 Vienna (Registration required) September 10, 2015, 9:00 – 18:00

90

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

INDUSTRY SPONSORED SYMPOSIA, SPONSORS AND EXHIBITORS Acknowledgements. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93 Sponsors‘ Company Descriptions. . . . . . . . . . . . . . . . . . . . . . . 95 Industry Sponsored Symposia . . . . . . . . . . . . . . . . . . . . . . . . . . 97 Exhibition Information. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 Exhibition Floorplan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104

INDUSTRY / EXHIBITION

This section contains information that is promotional in nature, distinct from the scientific / educational elements of the congress.

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PROGRESS AND POSSIBILITY IN IMMUNOLOGY.

VISIT ABBVIE AT BOOTH #111

Industry Sponsored Symposia, Sponsors and Exhibitors

ACKNOWLEDGEMENTS

ECI wishes to thank the following main sponsors for their support of ECI 2015 as follows:

SPONSORS PLATINUM SPONSOR

GOLD SPONSOR

SILVER SPONSORS

INDUSTRY / EXHIBITION

BRONZE SPONSOR

EFIS OFFICIAL JOURNALS

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biolegend.com

08-0052-04

Industry Sponsored Symposia, Sponsors and Exhibitors

SPONSORS’ COMPANY DESCRIPTIONS

nnAbbVie AbbVie, a global, research-based biopharmaceutical company, is committed to addressing some of today’s toughest health challenges. As a leader in Immunology, our scientists use their diverse perspectives and insights to develop new medicines and therapies for addressing chronic, progressive diseases. Our treatments and pipeline in Immunology are designed to target complex, unmet medical needs for patients suffering from difficult-to-treat autoimmune or immune-mediated inflammatory diseases. It’s all part of AbbVie’s promise to pursue the possibilities that help more patients lead healthier lives. nnBD Biosciences BD Biosciences, a segment of Becton, Dickinson and Company, is one of the world’s leading businesses focused on bringing innovative tools to life science researchers and clinicians. Principal product lines include flow cytometers and cell sorters, monoclonal antibodies and kits, reagent systems, and tools to aid in life science research, drug discovery and diagnostic assays. BD Biosciences customers are involved in basic research, discovery and development of drugs and vaccines, clinical trials, diagnostic testing, and disease management. This diverse customer base includes academic and government institutions, pharmaceutical and biotech companies, and clinical laboratories. nnBeckman Coulter Flow Cytometry – Research / Life Science Offering the broadest range of cellular analysis systems in the world, Beckman Coulter provides a variety of reagents, instruments and software to meet the diverse needs of today’s research laboratories. Our extensive line of reagents include human and non-human antigens, signal transduction and immunotoxicology. nnBioLegend BioLegend develops and manufactures world-class, cutting-edge antibodies and reagents for biomedical research, at an outstanding value to customers. The broad product portfolio includes flow cytometry, cell biology, and functional reagents for research in immunology, neuroscience, cancer research, stem cells, and more. BioLegend is certified for ISO 9001:2008 and ISO 13485:2003. nnMiltenyi Biotec Miltenyi Biotec provides products that advance biomedical research and cellular therapy. Our innovative tools support research from basic research to translational research to clinical application. Our more than 25 years of expertise includes immunology, stemcell biology, neuroscience, and cancer. Miltenyi Biotech as more than 1,500 employees in 25 countries. nnFresenius Medical Care/Therapeutic Apheresis Therapeutic Apheresis is a “special care” division of Fresenius Medical Care, the world’s largest provider of dialysis care products and services. nnWiley Wiley is a global provider of knowledge and knowledge-enabled services that improve outcomes in areas of research, professional practice and education. nnElsevier

INDUSTRY / EXHIBITION

Elsevier is a world-leading provider of scientific, technical and medical information products and services.

www.eci-vienna2015.org

Final Program • 4th European Congress of Immunology • September 6–9, Vienna/AT • ECI 2015

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Flow Cytometer

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The instrument is designed to be compact and fits easily on a bench top or a standard biohood. Twenty one (21) standard configurations are available to provide the ultimate in application flexibility with up to three lasers and 15 parameters. The CytoFLEX flow cytometer is easily installable and upgradeable. All lower configuration systems have full upgrade capability to higher configurations enabling future application expansion. Together, the CytoFLEX system and CytExpert software brings high performance flow cytometry to a variety of researchers with simple to complex needs.

Please contact your Beckman Coulter representative for more information.

For Research Use Only. Not to be used in diagnostic procedures. Beckman Coulter, the stylized logo, CytoFLEX, CytExpert and fast track to success. are trademarks of Beckman Coulter, Inc. Beckman Coulter and the stylized logo are registered in the USPTO.

Industry Sponsored Symposia, Sponsors and Exhibitors

INDUSTRY SPONSORED SYMPOSIA MONDAY nnIS.01

Industry Sponsored Lunch Symposium: Fresenius Medical Care New Treatment Opportunities with Immunoadsorption Technology

Chairperson:

Rudolf Valenta; Vienna, Austria

Hall F1 14:00 -15:30

Treatment of Encephalitis with Immunoadsorption Nico Melzer; Muenster, Germany Apheresis in Autoimmune Disease Georg Böhmig; Vienna, Austria New Option for Allergy Treatment. Why IgE? Rudolf Valenta; Vienna, Austria Questions and Answers

nnIS.02

Industry Sponsored Lunch Symposium: Beckman Coulter New reagent and instrument concepts for your Immunology research

Chairperson:

Andreas Böhmler; Krefeld, Germany

Hall N 14:00 -15:30

Innovative Technologies for phenotypic and functional Cell Characterization in Stem cell and Immune therapy Lutz Uharek; Berlin, Germany MAIT cells: their role in antibacterial immunity and beyond Emmanuel Treiner; Toulouse, France Small - smaller - smallest: Extracellular vesicles in inflammation Andreas Spittler; Vienna, Austria

nnIS.03

Industry Sponsored Evening Symposium: Phadia Austria GmbH (Thermo Fisher Scientific) Towards a molecular diagnosis of allergies

Hall F1 19:15 -20:15

Chairpersons: Petra Zieglmayer; Vienna, Austria / Rudolf Valenta; Vienna, Austria Molecular diagnosis of lgE-associated allergies Marianne van Hage; Stockholm, Sweden Early childhood lgE reactivity predicts later disease development Magnus Wickman; Stockholm, Sweden

nnIS.04

Industry Sponsored Progress in Technology Session: Pfizer Personalized Vaccinology

Hall G 19:15 -20:15

Chairpersons: Ursula Wiedermann; Vienna, Austria / Martina Prelog; Würzburg, Germany Vaccine responsiveness in patients with autoimmune disorders Martina Prelog; Würzburg, Germany

Vaccine failures ‑ why and what to do? Ursula Wiedermann; Vienna, Austria

nnIS.05

Industry Sponsored Evening Symposium Bristol-Myers Squibb (BMS) Immune checkpoint modulation – The standard in lung cancer and rheumatoid arthritis?

Chairperson:

Christoph Zielinski; Vienna, Austria

Hall N 19:15 -20:15

Rational to target immune checkpoints in diseases Eric Tartour; Paris, France Evolving immunotherapy combinations for cancer treatment Ignacio Melero; Pamplona, Spain Abatacept: T-cell modulation in rheumatoid arthritis. Clemens-Maria Scheinecker; Vienna, Austria

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INDUSTRY / EXHIBITION

Personalizing vaccination for high risk children Rita Carsetti; Rome, Italy

Value through Innovation

For more than 100 years we have demonstrated our strong research spirit in the interest of future generations. Research is our key to success. Thanks to our innovative medicines, Boehringer Ingelheim is one of the world’s top 20 pharmaceutical companies. Our global center for cancer research as well as facilities for biopharmaceutical research, development and production are located at the Boehringer Ingelheim Regional Center Vienna. In addition, the commercial activities for over 30 countries in Central and Eastern Europe are managed from the Vienna site. Having 1400 employees and investing around 200 million euros in nonclinical and clinical research, Boehringer Ingelheim is considered one of the most important employers in the Austrian life science sector. www.boehringer-ingelheim.at

Boehringer Ingelheim RCV GmbH & Co KG, Dr. Boehringer-Gasse 5-11, 1121 Vienna, phone 01/801 05-0*, fax 804 08 23

Industry Sponsored Symposia, Sponsors and Exhibitors

INDUSTRY SPONSORED SYMPOSIA TUESDAY nnIS.06

Industry Sponsored Progress in Technology Session: Fluidigm Connect cell diversity, stimulus and response with single-cell biology

Hall N 10:00 -11:00

The future of single-cell biology Mark Lynch / Robert Ellis; Amsterdam, The Netherlands Resolving bifurcation of Th1 and Tfh cell fates during Plasmodium infection using single-cell RNA sequencing Tapio Lonnberg; Hinxton, United Kingdom Further Topic & Speaker - To be confirmed

nnIS.07

Industry Sponsored Lunch Symposium: Becton Dickinson Revealing Immune Cell Biology with Multicolor Flow Cytometry

Chairperson:

Nicolas Quoix; Erembodegem, Belgium

Hall F1 14:00 -15:30

Optimizing Strategies for Reliable Multicolor Flow Data Guerric Epron; Erembodegem, Belgium

INDUSTRY / EXHIBITION

Nutrient control of stem cell and T cell differentiation Naomi Taylor; Montpellier, France

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HOW WOULD YOU USE £20 MILLION TO BEAT CANCER SOONER? This October Cancer Research UK will launch our Grand Challenge the world’s biggest boldest cancer grant. A series of £20 million awards for multinational, multidisciplinary teams willing to tackle the toughest questions in cancer today.

Find out more visit: cruk.org/grandchallenge #CRUKGrandChallenge

Cancer Research is a registered charity in England and Wales (1089464), Scotland (SC041666) and the Isle of Man (1103). C 2014 Cancer Research UK. The Cancer Research UK name and logo are registered trademarks of Cancer Research UK.

Industry Sponsored Symposia, Sponsors and Exhibitors

EXHIBITION INFORMATION

The exhibition is an important component of the ECI congress, providing participants with an ideal platform to network with industry partners in the field and an opportunity to gain further insights into the newest advancement from the industry side. 58 companies and publishers are exhibiting at the ECI 2015 congress. The technical exhibition takes place in the hall X2 on the level -2. Please see further details on pages 104 & 105.

Exhibition & Society Village - opening hours: Monday, September 7, 2015 Tuesday, September 8, 2015 Wednesday, September 9, 2015

9:00–18:00 9:00–18:00 9:00–16:30

Exhibitor Registration Counter Exhibitor badges and complimentary congress badges are available for pick-up at the exhibitor registration desk in the entrance hall. Opening times – please see Exhibition Service Desk. Exhibitor badges are to be used solely for staff members of the exhibiting companies and only allow access to the exhibition hall. The complimentary congress registrations allow access to the scientific sessions and receipt of the congress bag including final program. These are also to be used solely by staff members of the exhibiting companies, as they will not show a barcode on the badge, hence will not abtain any CME credits.

Exhibition Service Desk – opening hours Saturday, September 5, 2015 Sunday, September 6, 2015 Monday, September 7, 2015 Tuesday, September 8, 2015 Wednesday, September 9, 2015 Thursday, September 10, 2015

8:00–20:00 8:00–20:00 8:00–18:30 8:00–18:30 8:00–22:00 8:00–14:00

Exhibitor access Exhibitors may enter the exhibition area one hour prior to the official opening and must leave the exhibition halls at the latest 30 min after closing, therefore at 18.30. Meetings or customer events on the booth area before 9:00 and after 18:00 are not allowed.

INDUSTRY / EXHIBITION

Tickets to visit only the exhibition are not available.

www.eci-vienna2015.org

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Neurology journey through time

60 Years Novartis Neuroscience in Austria

Rilatin® / later Ritalin® Tegretol® Leponex® & Anafranil® Lioresal® Sirdalud® Trileptal® Comtan® & Exelon®

Datum der Erstellung: Februar 2015

Gilenya®

AT1503302302

Stalevo®

Novartis Pharma GmbH, Stella-Klein-Löw-Weg 17, 1020 Wien, Tel.: 01-866 57-0, Fax: 01-866 57 6353

Industry Sponsored Symposia, Sponsors and Exhibitors

EXHIBITION INFORMATION

Exhibitors (alphabetical) The following companies are exhibiting at the ECI 2015 (as per August 2015) Booth no.

Company Name

Booth no.

AbbVie Immunology R&D, North Chicago, Illinois, United States

111

MILTENYI BIOTEC GmbH, Bergisch Gladbach, Germany 112 MERCK SHARP & DOHME, Wien, Austria

133

Abcam plc, Cambridge, United Kingdom

114

PBL Assay Science, Piscataway, United States

143

AID GmbH, Straßberg, Germany

135

PEPperPRINT GmbH, Heidelberg, Germany

116

AYOXXA Biosystems GmbH, Köln, Germany

117

PeproTech EC Ltd., London, United Kingdom

142

BECTON DICKINSON FRANCE S.A., Erembodegem, Belgium

110

PerkinElmer Inc., Hopkinton, United States

115

BECKMAN COULTER Eurocenter S.A., Nyon 1, Schweiz 119 BioLegend, San Diego, United States

102

Bio-Rad Laboratories GesmbH, Vienna, Austria

125

BIO-TECHNE, Abingdon, United Kingdom

103

BioVendor Research & Diagnostic Products, Brno, Czech Republic

134

BIOZOL Diagnostica Vertrieb GmbH, Eching, Germany 136 Biozym Biotech Trading GesmbH, Wien, Austria

102

BRISTOL-MYERS SQUIBB GesmbH, Wien, Austria

113

Cell Signaling Technology, Leiden, Netherlands

126

CHEMOMETEC A/S, Allerod, Denmark

145a

CTL Europe GmbH, Bonn, Germany

105

Cytognos S.L., Flow Cytometry Solutions, Salamanca, Spain

144

Danone, Paris, France

100

eBioscience, an Affymetrix company, Wien, Austria

147

Enzo Life Sciences, Farmingdale, NY, United States

109

EXBIO Antibodies, Vestec, Czech Republic

129

Fluidigm Europe B.V., Amsterdam, Netherlands

123

Fresenius Medical Care Deutschland GmbH, Bad Homburg, Germany

122

Hycult Biotech, Uden, Netherlands

139

Illumina, San Diego, United States

140

Immudex, Copenhagen, Denmark

145b

IntelliCyt Corp., Albuquerque, United States

120

InvivoGen, Toulouse, France

106

Jackson ImmunoResearch Europe Ltd, Newmarket, United Kingdom

107

JPT Peptide Technologies GmbH, Berlin, Germany

124

LGC Standards, Teddington, Middlesex, United Kingdom Lophius Biosciences GmbH, Regensburg, Germany

Pivotal Scientific Limited, Oxfordshire, United Kingdom 128 PromoCell GmbH, Heidelberg, Germany

127

Proteintech Europe, Manchester, United Kingdom

146

QUANTA Biosciences, Germantown MD, United States 137 Randox Biosciences, Crumlin, Co. Antrim, United Kingdom

145

Seahorse Bioscience Europe, Copenhagen, Denmark 132 Sony Biotechnology Inc., San Jose, United States

101

STEMCELL Technologies, Grenoble, France

104

SYSMEX Europe GmbH, Norderstedt, Germany

141

Szabo-Scandic HandelsgmbH & Co KG, Wien, Austria 136 Thermo Fisher Scientific, Darmstadt, Germany

138

VWR International GmbH, Wien, Austria

137

Publishers ELSEVIER B.V., Amsterdam, Netherlands

P101

Wiley Blackwell, John Wiley & Sons, Oxford, United Kingdom

P102

Wisepress Ltd, London, United Kingdom

P103

S.KARGER AG, Medical and Scientific Publishers, Basel, Switzerland

P104

Frontiers, Lausanne, Switzerland

P105

Society Village American Association of Immunologists (AAI)

S10

British Society for Immunology (BSI)

S02

European Federation of Immunological Societies (EFIS) S09 French Society for Immunology (SFI)

S07

German Society for Immunology (DGfI)

S04

International Congress of Immunology (ICI 2016)

S01

130

International Union of Immunological Societies (IUIS)

S01

131

Irish Society for Immunology (ISI)

S05

Mabtech AB, Nacka Strand, Sweden

108

Italian Society for Immunology (SIICA)

S06

Merck Millipore, Vienna, Austria

121

Scandinavian Society for Immunology (SSI)

S08

Meso Scale Discovery, Rockville, United States

118

Turkish Society for Immunology (TSI)

S03

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INDUSTRY / EXHIBITION

Company Name

Industry Sponsored Symposia, Sponsors and Exhibitors

EXHIBITION FLOORPLAN LEVEL -2 Level

-2

Anouncement Industry Sponsored Sessions

S01

S02

Desk Poster Help Information

S03

S04

IUIS/ BRITISH TURKISH ICI 2016 SOC. SOC.

Society Village

Society Village

DGfI

Lecture halls

AAI

EFIS

100

S10

S09

S06

S07

Society Village

P102

ELSE- WILEY VIER

P103

P104

WISEPRESS

KARGER

CTL

STEM-CELL

BIO-TECHNE

BIOLEGEND

SONY

105

104

103

102

101

113

Poster Poster

106

INVIVO- JACKGEN SON

107

108

MAB- ENZO TECH

109

ABBVIE BECTON DICKINSON

116

117

AYO- MESOXXA SCALE

118

130

Level

0

132

134

PIVO- EXBIO TAL

FRESENIUS

BECKMAN COULTER

LGC LOPHIUS SEAHORSE MSD BIOVENDOR

AID

129

131

MERCK

120

121

145b

SZABO SCAN- QUANTA DIC

145

146

CELL SIGNALING 126 141

133

136

BIORAD 125

123

137

HYTHER- CULT MOFISHER ILLUMINA 138

145a

INDUSTRY / EXHIBITION

FLUIDIGM

139

IMMUPROCHEMO- DEX RAN- TEINDOX TECH METEC

JPT

124

122

INTELLICYT

135

114

112

119 128

ABCAM

Exhibition (X2) 110

PER- PEPKIN PERELMER PRINT

127

BMS PROMOCELL

111

MILTENYI BIOTEC

115

P105

S08

ISI SIICA FRENCH SOC. SSI FRONTIERS

Society Village & Publishers P101

DANONE

S05

140

142

SYS- PEPROMEX TECH

PBL

CYTOGNOS

143

144

147

eBIOSCIENCE

Exhibition (X2)

104

ECI 2015 • September 6–9, Vienna/AT • 4th European Congress of Immunology • Final Program

www.eci-vienna2015.org

€ €

Industry Sponsored Symposia, Sponsors and Exhibitors

EXHIBITION FLOORPLAN

S ge

PosterPoster AwardAward Candidates Candidates

Booth # Booth Company # Company name name

List of Exhibitors List of Exhibitors

€

€

Danone Danone Sony Biotechnology Sony Biotechnology Inc. Inc. BioLegend BioLegend Biozym Biotech Biozym Trading Biotech GesmbH Trading GesmbH BIO-TECHNEBIO-TECHNE STEMCELL Technologies STEMCELL Technologies CTL Europe GmbH CTL Europe GmbH InvivoGen InvivoGen Jackson ImmunoResearch Jackson ImmunoResearch Europe Ltd Europe Ltd Mabtech AB Mabtech AB Enzo Life Sciences Enzo Life Sciences BECTON DICKINSON BECTON DICKINSON FRANCE S.A.FRANCE S.A. AbbVie Immunology AbbVie Immunology R&D R&D MILTENYI BIOTEC MILTENYI GmbH BIOTEC GmbH BRISTOL-MYERS BRISTOL-MYERS SQUIBB GesmbH SQUIBB GesmbH Abcam plc Abcam plc PerkinElmerPerkinElmer Inc. Inc. PEPperPRINTPEPperPRINT GmbH GmbH AYOXXA Biosystems AYOXXA GmbH Biosystems GmbH Meso Scale Discovery Meso Scale Discovery BECKMAN COULTER BECKMAN Eurocenter COULTERS.A. Eurocenter S.A. IntelliCyt Corp. IntelliCyt Corp. Merck Millipore Merck Millipore Fresenius Medical Fresenius CareMedical Deutschland Care Deutschland GmbH GmbH Fluidigm Europe Fluidigm B.V. Europe B.V. JPT Peptide Technologies JPT Peptide Technologies GmbH GmbH Bio-Rad Laboratories Bio-Rad Laboratories GesmbH GesmbH Cell Signaling Cell Technology Signaling Technology PromoCell GmbH PromoCell GmbH Pivotal Scientific Pivotal Limited Scientific Limited EXBIO Antibodies EXBIO Antibodies LGC Standards LGC Standards Lophius Biosciences Lophius GmbH Biosciences GmbH Seahorse Bioscience SeahorseEurope Bioscience Europe MERCK SHARP MERCK & DOHME SHARP & DOHME BioVendor Research BioVendor & Diagnostic Research &Products Diagnostic Products

www.eci-vienna2015.org

100 101 102 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134

100 101 102 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134

AID GmbH AID GmbH BIOZOL Diagnostica BIOZOL Diagnostica Vertrieb GmbH Vertrieb GmbH Szabo-Scandic Szabo-Scandic HandelsgmbH HandelsgmbH & Co KG & Co KG QUANTA Biosciences QUANTA Biosciences VWR International VWR International GmbH GmbH Thermo Fisher Thermo Scientific Fisher Scientific Hycult Biotech Hycult Biotech Illumina Illumina SYSMEX Europe SYSMEX GmbH Europe GmbH PeproTech ECPeproTech Ltd. EC Ltd. PBL Assay Science PBL Assay Science Cytognos S.L.Cytognos S.L. Randox Biosciences Randox Biosciences Proteintech Europe Proteintech Europe eBioscience eBioscience CHEMOMETEC CHEMOMETEC A/S A/S Immudex Immudex

Booth # Booth # 135 136 136 137 137 138 139 140 141 142 143 144 145 146 147 145a 145b

135 136 136 137 137 138 139 140 141 142 143 144 145 146 147 145a 145b

ELSEVIER B.V. ELSEVIER B.V. P101 Wiley Blackwell, WileyJohn Blackwell, Wiley &John SonsWiley & Sons P102 Wisepress Ltd Wisepress Ltd P103 S.KARGER AG, S.KARGER Medical AG, andMedical Scientific and Publishers Scientific Publishers P104 Frontiers Frontiers P105

P101 P102 P103 P104 P105

PublishersPublishers

INDUSTRY / EXHIBITION

CompanyCompany name name

Poster Poster

Society Village Society Village InternationalInternational Congress of Congress Immunology of Immunology (ICI 2016) (ICI 2016) S01 InternationalInternational Union of Immunological Union of Immunological Societies (IUIS) Societies S01 (IUIS) British Society British for Immunology Society for Immunology (BSI) (BSI) S02 Turkish Society Turkish for Immunology Society for Immunology (TSI) (TSI) S03 German Society German for Immunology Society for Immunology (DGfI) (DGfI) S04 Irish SocietyIrish for Immunology Society for Immunology (ISI) (ISI) S05 Italian Society Italian for Immunology Society for Immunology (SIICA) (SIICA) S06 French Society French for Immunology Society for Immunology (SFI) (SFI) S07 ScandinavianScandinavian Society for Immunology Society for Immunology (SSI) (SSI) S08 European Federation EuropeanofFederation Immunological of Immunological Societies (EFIS) Societies S09(EFIS) American Association American of Association Immunologists of Immunologists (AAI) (AAI) S10

S01 S01 S02 S03 S04 S05 S06 S07 S08 S09 S10

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EFIS Info . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 108 Appointments with EFIS during the ECI 2015. . . . . . . . . . . . . 109 Upcoming Meetings (Sponsored by EFIS) . . . . . . . . . . . . . . . 109

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EFIS

INFO

The European Federation of Immunological Societies (EFIS) is a non-profit umbrella organization that represents 31 immunological societies from all across Europe, and even beyond the borders to Israel. Every active member of any of our member societies is automatically considered an EFIS member and can as such benefit from the EFIS programs. Thus EFIS represents more than 14,000 individual immunologists. The main goals of EFIS are the support of immunological research and education as well as strengthening scientific interaction amongst its members. EFIS especially focuses on supporting early career scientists, e.g. through fellowships or travel grants. The EFIS was founded at a meeting held in Amsterdam in September 1975. In the beginning, the legal body of this society was the International Union of Immunological Societies (IUIS). During a meeting held in Helsinki in 1991, it was decided to incorporate the articles in a notarial deed. EFIS was registered as an individual legal body on the 5th of April 1995, in the form of a society as was stated in the deed of notary Oosterdijk. See the EFIS website www.efis.org to read the statues of EFIS and the minutes of previous EFIS general assemblies.

EFIS Board The EFIS Board is composed of the President, the Vice President, the Past President, the Treasurer and the Secretary General. The Board meets about three times a year. Board Members are elected by the EFIS General Assembly, composed of delegates of national societies (each society is entitled to have one delegate per 500 members), and they are appointed for a period of three years. Lorenzo Moretta (Rome, Italy) President Ospedale Pediatrico Bambino Gesù V.le Ferdinando Baldelli, 41 00146 Rome [e]: [email protected]

Anna Erdei (Budapest, Hungary) Secretary General Department of Immunology University Eötvös Lorand Pazmany s. 1/C H-1117 Budapest, Hungary [e]: [email protected]

René A.W. van Lier (Amsterdam, Netherlands) President elect Sanquin Blood Supply Foundation Plesmanlaan 125 1066 CX Amsterdam [e]: [email protected] Catherine Sautès-Fridman (Paris, France) Past President Centre de recherche des Cordeliers, UMRS 872 15, rue de l'école de médecine F-75006 Paris, France [e]: [email protected]

Hannes Stockinger (Vienna, Austria) Treasurer Institute for Hygiene and Applied Immunology Center for Pathophysiology, Infectiology and Immunology Medical University of Vienna Lazarettgasse 19 A-1090, Vienna, Austria [e]: [email protected]

Contact For general inquiries, please contact:

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Mr. Thomas Wiley EFIS Coordinator [e]: [email protected] [m]: 0039 347 197 7015

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EFIS

APPOINTMENTS WITH EFIS DURING THE ECI 2015

Mark your congress program app to make sure you don’t miss these important EFIS events!

Monday, September 7th - EFIS Awards Lecture Symposium, featuring the winners of the EFIS-IL Most Cited Article and Review Prizes and the EFIS-EJI Ita Askonas Prize, as well as the Laureates of the ACTERIA Prizes awarded by EFIS, from 14:00 – 15:30 c/o Hall F2 of the Austria Center. - "Bright Sparks" Workshops, throughout the day on Monday (c/o Hall F1), during which the 24 authors of abstracts selected by the ECI 2015 Scientific Program Committee will present their work. In addition to her/his recognition as an ECI 2015 "Bright Spark", all speakers in Bright Sparks Workshops will also receive a EUR 500,- cash prize (made possible in part by BioLegend). - Meet the Editor of Immunology Letters, Vito Pistoia, c/o the EFIS Booth from 14.00 to 15.00. - Meet the Editors of European Journal of Immunology - with Hans-Martin Jäck, Steffen Jung and Andreas Radbruch c/o the EFIS Booth from 17.00 to 17.45.

Tuesday, September 8th - Meet the Editors of European Journal of Immunology - with Britta Engelhardt and Francesco Annunziatoc/o the EFIS Booth from 9.45 to 11.15. - Meet the Editors of European Journal of Immunology - with Francesco Annunziato, Hans-Martin Jäck and Andreas Radbruch- c/o the EFIS Booth from 17.00 to 17.45.

Wednesday, September 9th - The inaugural EFIS President’s Symposium, convened by standing EFIS Board President, Prof. Lorenzo Moretta, from 9.45 to 11.15 c/o Hall A, entitled “On NK Cells and NK Cell-Based Therapy of Leukemias”. - Meet the Editor of Immunology Letters, Dr. Vito Pistoia, c/o the EFIS Booth from 12.30 to 13.30. ECI 2015 delegates are also cordially invited to visit the EFIS Booth c/o the Immunology Village for a coffee and to take part in the traditional “EFIS Passport to Prizes” raffle for a chance to win numerous prizes, including travel grants to future immunology events and subscriptions and textbooks from EFIS’ Official Journals.

UPCOMING MEETINGS (SPONSORED BY EFIS) 2015

2016

September 16 – 18, 2015 Cancer: Inflammation and Immunity Finale Ligure, Italy www./nibit.org/meeting/index.php

August 21 – 26, 2016 16th International Congress of Immunology - ICI 2016 Melbourne, Australia www.ici2016.org

October 06 – 08, 2015 15th International Conference on Progress in Vaccination Against Cancer - PIVAC15 Tübingen, Germany www.eacr.org/pivac15/

2018 September 12 – 15, 2018 5th European Congress of Immunology - ECI 2018 Istanbul, Turkey www.eci2018.org

October 07 – 09, 2015 Natural Killer Cell Symposium Göttingen, Germany www.nk-symposium.org October 16 – 19, 2015 7th EFIS/EJI South East European Immunology School Becici, Montenegro www.bnitm.de/seeis2015

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International Congress of Immunology 2016 Invitation from the ICI 2016 President ICI 2016 promises to be an unforgettable event that will bring together delegates from all over the world. We anticipate over 3000 participants, including international leaders at the forefront of the discipline that will present the most recent advances in basic immunology and clinical treatments. This is an opportunity to be part of a major international immunology meeting in Australia as the last ICI was held in Sydney back in 1977. The Congress will provide a key networking and educational interface for colleagues from industry, university, health providers and independent research organisations to come together.

Jose Villadangos President, International Congress of Immunology 2016 Peter Doherty Institute and Bio21 Institute, The University of Melbourne

Scientific Program Highlights The following disciplines / themes will form part of the program. Innate immunity

Dendritic cells

Inflammation

T cell differentiation

Acquired immunity

B cell immunity

Vaccines

Life and death decisions in the immune system

Tumour Immunology Transplantation Allergy Autoimmunity and the maintenance of tolerance Immunoregulatory gene networks Immune deficiencies

Metabolic control of immunity Regulation of the immune system by commensal flora Immunotherapeutic drugs Therapeutic antibodies Mathematic modeling of immune responses.

FAST FACTS

IMMUNOTHERAPY: HARNESSING THE POWER OF THE IMMUNE SYSTEM

Registration opens September 2015 Call for Abstracts open July 2015

ICI 2016

www.ici2016.org Come and say G’day in Melbourne in 2016! Experience the best that Melbourne has to offer – its beaches, entertainment, heritage, culinary traditions, food and wine, festivals, sporting events, friendly people and much more. Melbourne is recognised as an R&D centre of excellence in medical science, business and finance. With Australia’s most culturally diverse population, and repeatedly voted the world’s most liveable city, Melbourne has something to offer for everyone. It is also the perfect opportunity to discover Australia’s famous destinations: the Great Barrier Reef, Twelve Apostles, Ayers Rock, the Sydney Opera House, the iconic MCG Stadium and so much more!

Hosted by

Supported by

Congress Managed by Arinex Pty Ltd 91 – 97 Islington Street, Collingwood Victoria 3066 Australia P: +61 3 8888 9510 F: +61 3 9417 0899 E: [email protected]

NETWORKING EVENTS Networking Events. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112

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Networking Events

NETWORKING EVENTS

Historic Exhibition Emerging Immunology – Vienna’s Contribution Opening: Sunday, September 6 | 19:00 | Austria Center Vienna | Level 0 Exhibition Opening Hours: Sunday, September 6 – Wednesday, September 9 | Austria Center Vienna | Level 0 Vienna has been a cradle of immunology research at the end of the 19th beginning of the 20th century. In fact, some outstanding immunologists around Karl Landsteiner, discoverer among many other immunologically relevant findings of human blood groups, and Clemens von Pirquet, who coined the term ‘allergy’, made ground-breaking contributions to early immunology research. It was the time when the concepts of active and passive vaccination started to become understood from a mechanistic point of view and first preventive but also therapeutic treatment modalities for the devastating infectious diseases threatening large parts of our population at that time became feasible. Some of the outstanding Austrian immunologists - from Karl Landsteiner to Clemens von Pirquet including their colleagues and contemporaries - will be commemorated in this exhibition, which has been curated by Johann Eibl, Othmar Förster and Winfried F. Pickl. Moreover, a short outlook describing major immunology research centers in the Vienna area in the 21st century will be provided.

Networking Mixer Sunday, September 6 | 19:00 | Austria Center Vienna | Level 2 We are pleased to invite you to our Networking Mixer that will take place just after the opening ceremony, starting at 19:00. There you can catch up with “old” colleagues and friends and meet new ones. Having always been a melting pot for numerous cultures, Vienna has strongly been influenced among others, by Jewish, Balkan and Turkish traditions. That is why Klezmer, Kebab, and Coffee have grown to become almost as Viennese as Apfelstrudel and Johann Strauss. You will be able to get a taste of very diverse and wonderful Viennese traditions while being surrounded by an international atmosphere. We are looking very much forward to an interactive, delightful & multicultural evening! Buffet: traditional Viennese cuisine with a touch of international street food. One of our three music acts will be playing in each corner of the triangle-shaped location. Classic: Klezmer: Jazz:

Michael Zlabinger (string quartett) Frejlech Thomas Kugi & Band

The event is entirely at the participants’ own expenses. Participation is included in the registration fee but registration for the event is necessary in advance. No sponsoring is used to fund any part of the evening.

ECI Bright Sparks Pub Crawl Monday, September 7 | 20:15 | Wiener Naschmarkt The ECI 2015 Bright Sparks Pub Crawl connects international Early Career Scientists with their Austrian colleagues to foster networking between the future experts of the discipline. Since networking, apart from many other skills, is an important ingredient of a successful scientific career, ECI offers an informal platform for the facile exchange of thoughts, experiences and perspectives within the community of Early Career Scientists. For that purpose, ECI organizes an event exclusively for this group of participants. We would like to invite our international colleagues to visit typical places in Vienna and to enjoy Viennese hospitality. How to register: Please register at the onsite registration desk. Participants will receive a coupon stating the assigned group, meeting time and meeting point. Participants are divided into 10 groups with approx. 30 people and two local hosts. Each group will be assigned to two different Pubs. The first location is exclusively for the assigned group whereas the second location is a melting pot for all groups. Meeting time: Meeting Point:

20:15 Foyer Hall E / Level 0

Departure: a group departs as soon as the group is complete The event is entirely at the participants’ own expenses. No sponsoring is used to fund any part of the evening.

ECI Networking Heurigen Evening Tuesday, September 8 | 19:15 Enjoy a nice exclusive evening with your colleagues at a traditional Viennese “Heurigen” wine tavern where you are served with wine produced from the surrounding vineyards. We will take you to the picturesque village of Gumpoldskirchen, where you will have the opportunity to experience a very typical Austrian summer evening tradition: enjoying a glass of local wine together with rustic food and embedded into authentic ‘Heurigen’-culture while being surrounded by vineyards. Price per Person: EUR 60,-/limited availability Price includes: shuttle bus to and from Gumpoldskirchen, a meal (a variety of cold & warm dishes), 3 x 0,25 liter of red-or white wine or soft drinks or water. Participants are assigned to a specific Heurigen for Dinner. They will receive one ticket for Dinner & Shuttle Bus together with three tickets for drinks. After Dinner Guests are free to walk around in the picturesque streets or change to another Heurigen to meet their colleagues. 19:15 – 19:30: 20:00: 20:30: From 22:30:

Departure with shuttle busses from the congress venue Reception and folklore dance show at Gumpoldskirchen Dinner and Music at the assigned Heurigen Shuttle busses back to Vienna City Centre (Opera House)

The event is entirely at the participants’ own expenses. No sponsoring is used to fund any part of the evening.

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THE CITY OF VIENNA The City of Vienna. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 114 Vienna City Map. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116 Vienna Public Transport Map . . . . . . . . . . . . . . . . . . . . . . . . . 118

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The City of Vienna

THE CITY OF VIENNA

Where to go in Vienna – Dancing, Beer Gardens, Restaurants - websites If you like fine dining, casual beer gardens, to party, dance or just sit in a bar, there are many places to go to, with a wide range of different music styles. We understand that not everyone has the desire nor the energy to dance the night away after a long day at the congress so do not forget that there is always the possibility to spend a very calm evening in a hotel bar, typical Viennese restaurant or one of the many fantastic coffee houses dotted around the city. The following links will make it easy to find your favorite place according to your mood: www.wien.info/en/shopping-wining-dining/restaurants www.wien.info/en/lifestyle-scene/nightlife

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Public Transportation The fastest and cheapest way to move around Vienna is by public transportation. The easiest to use is the metro – with 5 different lines (identifiable by different colors) running from 5 am to midnight on Mondays-Thursdays as well as Sundays and 24 hours on Fridays, Saturdays and holidays. A regular one-way fare costs EUR 2,20. Twenty-four-, 48- and 72-hour tickets cost EUR 7,60; EUR 13,30; and EUR 16,50; respectively. Tickets are checked before boarding and it may be a good idea to get a deal using multiple-trip tickets. Tickets for public transport can also be purchased online. There are several types of tickets ranging from single fare to weekly ticket. These tickets are valid for all public transportation services in Vienna (busses, trams, subways).

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Business Travel

HIGHLIGHT

What I especially look forward to about flights with myAustrian? First class service, delicious food – and Austrian hospitality. the charming way to fly

The City of Vienna

VIENNA CITY MAP

Vienna City Hall

Hotel Intercontinental

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The City of Vienna

VIENNA CITY MAP ALL DISTRICTS OF VIENNA

ACV

LEGEND

© FREYTAG-BERNDT u. ARTARIA KG, 1230 VIENNA, AUSTRIA, EUROPE

FIRST DISTRICTS - CITY

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The City of Vienna

VIENNA PUBLIC TRANSPORT MAP

ACV

© Wiener Linien, Okt. 2014

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Notes

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Notes

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