Idea Transcript
USE CONDITIONS
about a portal
READ US AND GOOD LUCK! Diseases
Symptoms
Drugs
Reference book
Dictionary of terms
MEDICALMED.US" DRUGS" OTHERS
Dimexidum The description is actual on 08.10.2015 Latin name: Dimexid ATH code: M02AX03 Active ingredient: Dimexidum (dimethyl sulfoxide) / Dimexid (Dimethyl sulfoxide) Producer: PAO "Galichfarm", PAO "Lubnyarm", Ukraine Redkinsky experimental plant, JSC Tatkhimfarmpreparata", LLC Tula Pharmaceutical Factory, Russia RUP of "Belmedpreparata", Republic of Belarus
Drug photo Structure
Release form
Pharmacological action
Indications to use of Dimexidum Interaction
Terms of sale
At pregnancy and a lactation
Contraindications Storage conditions
Responses
Pharmacodynamics and pharmacokinetics Side effects
Application instruction of Dimexidum
Period of validity
Special instructions
Overdose
Analogs
For children
How much is in a drugstore Dimexidum?
Structure of Dimexidum The concentrate for preparation of solution of Dimexidum contains not less than 99% of a dimethyl sulfoxide (DMSO) in not divorced look. Gel Dimexidum contains in the structure DMSO in concentration 0,25 mg/g or 0,5 mg/g, and also nipagin, nipazol, sodium a karmelloza, the purified water. Ointment Dimexidum prepare on the basis of gel poly(ethylene oxide) 1500 (for giving to drug of a necessary consistence add emulsifier to it) or on the basis of mink oil. Concentration of active agent — from 30 to 70%. DMSO also is a part of some gels and ointments (Triakort, Dolobene, Hondroksid, Kapsikam, Remisid, Ketorol),
And whether you know...
however in them it carries out function of a penetrator, but is not actively operating substance.
Pyrazinamidum, side effects
Contain DMSO and candles Propolis-. In addition substances are a part of medicine extract of propolis of 20% and cocoa butter.
Release form
Spray Evkazolin
Dimexidum is issued in shape: concentrate for cutaneous use of 990 mg/ml (bottles of 50 and 100 ml); % gel 25 and 50 (aluminum tubas on 30 and 40 g).
Olanzapine
Pharmacological action Sotaleks
Antiinflammatory, analgeziruyushchy.
Pharmacodynamics and pharmacokinetics Dimexidum — what is it?
Wikipedia answers the question "What Is Dimexidum?" that this outside medicine which is applied mainly to stopping of pain and an inflammation at diseases of the musculoskeletal system (MS), and also to strengthening of penetration into fabrics of some other drugs.
Pharmacodynamics
The mechanism of action of DMSO is connected with ability of this substance to inactivate hydroxylic radicals and to improve the course of exchange processes in the inflammation center.
Drug has local analgeziruyushchy and anesthetic effect. Finds moderate fibrinolitic and antiseptic activity. DMSO contributes to normalization of processes of formation of fibrin, improves microcirculation in fabrics, inhibits aggregation of erythrocytes and a chemotaxis of neutrophils, increases activity and intensity of phagocytosis, reduces the maintenance of the CEC. At topical administration quickly and well passes through biological membranes (mucous, skin, cell walls of bacteria), increasing their permeability for other drugs. These DMSO properties allow to use it as the transporter of other drugs through mucous and skin.
Pharmacokinetics
At application on mucous or skin it is soaked up quickly and almost in full. Bioavailability — 60-70%. And penetration depth and an indicator of bioavailability of DMSO are directly proportional to its concentration. After drawing on skin drug is found in blood serum in ten minutes. Concentration reaches peak values in four-eight hours. Well like in cells of fabrics of all bodies. An exception — cells of nails, hair, an adamantine substance of tooth. In an organism of DMSO is oxidized to a metilsulfonilmetan and then it is recovered to methyl thiomethane. Active agent and products of its metabolism are removed with excrements and urine. Besides, DMSO can be removed through lungs and skin that is followed by emergence of a specific garlick smell. Even at prolonged use of Dimexidum DMSO and its metabolites do not collect in an organism.
Indications to use of Dimexidum Dimexidum is allowed for use in medicine since 1971. Indications to use of medicine: sprains; hypostases of various etiology; purulent wounds; phlegmons; trophic ulcers; lymphostasis; burns; hemorrhages in joints; thrombophlebitises (acute or chronic); eczema; erysipelatous inflammation; diffusion streptoderma; keloid hems; diskoidny lupus erythematosus; limited scleroderma; alopecia; pyoderma; knotty erythema; furunculosis; acne. According to the instruction of the producer, application with Dimexidum appoint at such diseases the ODE as the deforming osteoarthrosis (in case of defeat of periartikulyarny fabrics), an ankylosing spondylitis, a pseudorheumatism, a reactive synovitis, radiculitis. Drug is used in combination with other drugs and procedures. Dimexidum is effective at bruises and at gout, it is used for acceleration of a rassasyvaniye of traumatic infiltrates and for treatment of a calcaneal spur. At a number of neurologic diseases, and also at impossibility of use of the NPVP peroral forms (for example, at a peptic ulcer), the electrophoresis with Dimexidum can be recommended. Resort to such way of treatment when it is necessary to kill a joint pain, pain at osteochondrosis or posttraumatic pain (including if at the patient the nerve is affected). In skin and plastic surgery Dimexidum is used for conservation of the skin gomotransplantat, and also for processing replaced skin gomo-and autografts. In stomatologic practice means is applied at inflammatory processes in maxillofacial area and inflammatory defeat of sialadens, at a pulpitis, a periodontal disease, periodontitis, arthritis / atroze a temporal and mandibular joint. Indications to use in gynecology are the colpitis, an erosion of a neck of uterus, an endometritis, an adnexitis, the milkwoman, the complications developing after gynecologic operations and childbirth, etc. Thanks to bactericidal and antiinflammatory properties drug is quite often used in cosmetology. The mask with Dimexidum and Solkoseril is considered one of the most efficient means from wrinkles and the best replacement of a mesotherapy and to Botox injections, and compresses and wrappings with solution help to reduce displays of cellulitis. Besides, cosmetologists recommend drug as means against spots. Masks for hair with natural oils and Dimexidum reduce a hair loss and stimulate their growth.
Contraindications Contraindications to use: intolerance of components of drug; insufficiency of function of livers/kidneys; stroke; the expressed atherosclerosis; stenocardia; myocardial infarction; cataract; glaucoma; coma; pregnancy; lactation. At purpose of drug consider what it is capable to strengthen not only activity, but also expressiveness of toxic effects of a number of drugs. At a proglatyvaniye even of a small amount of a dimethyl sulfoxide, and also in case of use for applications in an oral cavity, the patient can have a gastric disturbance or enterospasms.
Side effects Most of patients has no side effects against drug use. However development of pruritic dermatitis is in some cases possible. Sometimes patients badly perceive a specific smell of Dimexidum that can become the reason of emergence of nausea and desires on vomiting. In isolated cases it is possible bronskhospazm.
Application instruction of Dimexidum Dimexidum solution: application instruction
Solution on the basis of a concentrate Dimexidum (Dimexidum Zhff, Dimexidum Lugal) is applied as means of outside therapy. Use it for washing of the struck body surfaces (orosheniya) and in the form of applications. In solution of the necessary concentration moisten a gauze napkin and put it for 20-30 minutes on the struck place. From above the napkin is covered with a polyethylene film and linen (or cotton) fabric. It is recommended to repeat procedures 1-3 rubles/day (depending on indications) within 10-15 days. How to part Dimexidum the concentrate depends on that, medicine for what purpose prepares. For treatment of trophic ulcers 30-50% dimethyl sulfoxide solution (for one processing use from 50 to 100 ml of liquid), eczemas — solution with concentration of 40-90% are used. For a local anesthesia drug is used by 2 or 3 rubles/day in the form of compresses from 25-50% solution. A single dose — from 100 to 150 ml. At joint pains (for example, at an atroza of a knee joint) lotions on a joint with the drug divorced to the same concentration are shown. Compresses with Dimexidum for a knee or an ankle impose for 20-60 minutes. The course is calculated on 15-20 procedures.
If the center of defeat is localized on a highly sensitive body part, a concentrate dissolve 10-30% of solution before receiving. To the patients who underwent skin plastic surgery on replaced gomo-and autografts directly after operation and before permanent engraftment of a transplant apply further bandages, the impregnated 10-20% Dimexidum solution. For preservation of skin gomotransplantat 5% DMSO solution in Ringer's solution are used. Less strong solutions are applied to washing of inflammatory and is purulent - the necrotic centers and cavities.
Gel Dimexidum: application instruction
Gel (ointment) is applied as means of outside therapy to treatment of patients is more senior than 12 years. Means is applied on an affected area of a body with a thin layer from 1 to 3 rubles/day. Gel of 50% is intended for processing of an integument, for mucous it is recommended to use gel of 25%. The course lasts from 10 to 15 days. It is possible to repeat it not earlier than in 10 days. At a diffusion streptoderma, eczema, and also applications with gel (50%) in the form of compresses are applied to a local anesthesia. Procedure is repeated by 2-3 times during the day. At thrombophlebitis to the patient appoint simultaneous applications of Dimexidum with gel of heparin or Unguentum Heparini. Application should do to 2-3 rubles/day. The course is calculated on 10-15 procedures. In skin and plastic surgery apply bandages from 25% skin gomo-and autografts gel. The first bandage is applied at once after operation, further it is necessary to repeat procedures before permanent engraftment of an implant.
How to dissolve drug for joints at gout?
At diseases of rheumatic type (in particular, at gout) compresses with Dimexidum allow to reduce significantly pain and to quickly remove an inflammation in them. Well getting into fabrics, drug promotes gradual dissolution of salt outgrowths on the joints of ossicles of foot and joints struck with pathological process. For preparation of a compress the concentrate is parted in the equal volume of water of room temperature. Then the cut of a gauze is put in several layers, impregnated in the received solution, put to a sore point and warm it polyethylene, cotton fabric and a woolen scarf. Influence time — of 20 minutes before half an hour. Treatment depending on extent of damage of joints lasts from 10 days to 2 months. As Dimexidum is a good transporter of other drugs, before its use for strengthening of effect it is possible to grease a sore joint with antiinflammatory ointment / gel (Bystrum-gel, Hondroksid and their analogs). For stopping of megalgias Dimexidum (30 ml) can be mixed with two-percent solution of Novocaine (50 ml). The bandage is applied in the same sequence. Influence time — of 30 minutes till 1 o'clock.
How to part Dimexidum for a compress at spurs on heels?
At a calcaneal spur for simplification of a condition of the patient and improvement of quality of his life Dimexidum is used in a small dosage in the form of compresses or washings. To prepare solution, the concentrate is parted with water in the ratio 1:5. Then the napkin moistened in liquid is imposed on a sore heel and from above put on a sock. Influence time — 30 minutes. The effect of procedure will be more expressed if in 15 minutes prior to overlaying of a compress in a sore point to rub protivovspalitelny ointment. For anesthesia it is recommended to add to solution of Dimexidum solution of the Hydrocortisone, Dropiredol, Novocaine, Analginum. Such structure gives the best antiinflammatory and analgesic effect. It is necessary to clean a compress not later than in 40 minutes, otherwise there can be an irritation of skin.
What Dimexidum is applied in pediatrics to?
At children Dimexidum is applied to treatment of diseases the ODE, inflammatory, purulent and cankers of skin, an ugly face, eczema, a streptoderma, burns, and also diseases of upper parts of a respiratory path. Compresses with drug well warm up, stop inflammatory process and relieve of the cough irritating a throat. Such treatment is reasonable at pharyngitis, tonsillitis, quinsy. Dimexidum compress proportions with Novocaine for cough the following: three-four parts of water on one part of a concentrate (the age of the child is less, the less strong solution should be prepared). For preparation of structure it is possible to take on two parts of a concentrate one part of water, one part of the juice which is wrung out from stalks by an aloe and two parts of the honey kindled on the water bath. Before use mix is a little warmed up. The gauze put five times and moistened in the turned-out mix is put to a throat and fixed polyethylene and cotton fabric, and then a scarf in the beginning. Remove a compress in 50 minutes (at emergence of burning — earlier). To carry out procedure one night better. At bronchitis compresses with Dimexidum promote relaxation of bronchial tubes and improvement of blood circulation. The instruction on a compress with Dimexidum and Novocaine to the child following: one tablespoon of a concentrate dissolve in the same volume boiled / distillirovanoy waters, then in the received mix pour sodium diclofenac (one ampoule) and 10 ml of two-percent solution of Novocaine. The gauze impregnated with means is imposed on feet, a back (in shovels) and a breast, covered with polyethylene and fixed bandage (scarf). The child is covered with a blanket. Procedure duration — 30 minutes. Compresses do to 1 ruble/day for a week and only provided that the child has normal temperature. Medicine is used in a warm look (but we do not heat!). Imposing a gauze on a breast, it is necessary to avoid area of heart. Contraindications to use in pediatrics are pathologists of heart, vessels, kidneys and a liver, a problem with immune system, age till 12 years, the increased body temperature.
Use in gynecology: how to do tampons with Dimexidum?
Dimexidum in gynecology is used in the form of vaginal tampons. For preparation of medicinal mix one part of a concentrate is parted in five parts of water, and then add to the received solution aloe juice, antibiotics or Lidaza. Ready tampons which women use at menstrual bleedings are not suitable for treatment as they quite often become impregnated with various structures which can react with a dimethyl sulfoxide. Therefore tampons should be done independently of sterile cotton wool.
It is necessary to enter a tampon into a vagina so that it could be got easily. Active agent is quickly absorbed, getting to the inflamed ovaries or a uterus even at superficial introduction. Duration of each procedure, as well as course duration, depend on degree of neglect of pathological process. For strengthening of efficiency of the main treatment doctors sometimes recommend to use as a supportive application the drug Propolis-. Thanks to presence at structure of these candles of propolis and DMSO they well anesthetize, stop inflammatory process, render antibacterial action, promote strengthening of immunity and increase efficiency of the main therapy. It is necessary to apply them twice a day on one within 10-14 days.
Dimexidum for hair
Use of Dimexidum in combination with natural oils and vitamins promotes improvement of structure, and also acceleration of growth of hair. What is a dimethyl sulfoxide? The conductor for other substances and a universal stimulator of metabolic processes. Mask with Dimexidum for the hair inclined to fat content: one part of a concentrate of Dimexidum, by one part of ampullary solutions of vitamins A and E, one part of lemon juice (juice it is possible at desire to replace with vodka, cognac or 70-tigradusny alcohol). Such structure on hair it is necessary to hold no more than half an hour. Good responses of trichologists also the mask for an oily hair on the basis of Dimexidum (1 h a spoon) deserved, macadamia oil (1 h a spoon), almonds oil (1 h a spoon), egg (1 piece), cognac (1 tablespoon). Mix is applied on hair for half an hour, then washed away with shampoo and rinse hair water with lemon juice. For preparation of a mask for growth of hair and strengthening of bulbs, it is necessary to mix the castoric and burdock oils taken in equal volumes, to add to them Solutio oleosa of vitamins E and And (on one ampoule) and 5 drops of juice of a lemon. Ingredients carefully mix and pour to them in 1 tablespoon of a concentrate of Dimexidum. After the structure is applied on roots of hair, put on a polyethylene hat the head and tie a towel. In an hour (at emergence of burning — immediately) hair wash out with shampoo. Well affects hair and similar structure in which lemon juice is replaced with a yolk of one egg. For stimulation of growth of hair use a mask with sea-buckthorn oil. For preparation of structure it is necessary to mix the warmed-up oil with a concentrate in a proportion 3:1. Mix is rubbed in roots of hair, warmed polyethylene and a towel, washed away in an hour. Instead of a conditioner at the end of procedure it is possible to use 1:10 apple cider vinegar divorced water in a proportion. About Dimexidum for growth of hair in the majority positive, however it is necessary to remember that drug is powerful pharmaceutical tool which has a number of protivopopokazaniye and can cause quite severe burn.
Dimexidum for the person
In cosmetology for the person Dimexidum it is used for improvement of a condition of the withering skin, and also for treatment of skin, problem, inclined to rashes. Very effective remedy for fight against wrinkles and a face rejuvenation is the mask from Dimexidum and Solkoserila. For a start it is necessary to part one volume of a concentrate in ten volumes of boiled water and to carefully wipe face skin with this solution. Then put Solkoseril. Procedure duration — one hour. During all this time the mask needs to be sprinkled warm water that it did not stiffen. In an hour gel (or ointment) is removed a wet cotton plug, and skin is moistened with cream. For prevention of wrinkles the mask can be done 1-2 times a month, in the presence of deep wrinkles — times in three days within a month. Not less popular conditioning agent is both the face pack with Dimexidum and oil of a melaleuka (a tea tree). Such structure well treats pyoinflammatory damages of skin. For preparation of a mask it is necessary to mix equal volumes of 10% aqueous solution of Dimexidum and essential oil. Means is put on a face by means of a wadded sponzh pointwise at several o'clock or for the night, and then wash away its remains warm water. At emergence of burning the mask is washed away immediately.
Dimexidum from spots
The easiest route of administration from spots — daily wiping of the sites affected with an acne illness Dimexidum solution (concentration of DMSO — no more than 10%). Procedure is repeated twice a day. However responses demonstrate that the best results can achieve, using more complex mixes. It is possible to dissolve two tablets of Erythromycin in 10% solution of drug, and it is possible to mix four tablespoons of a concentrate from 50 ml of two-percent salicyl alcohol, 40 ml of glycerin and contents of 10 ampoules of ten-percentage solution of the Dioxidin. Both structures follow applies on problem sites of skin twice a day. Very powerful tool from spots — the structure prepared from 40 ml of salicyl alcohol (2%), 10 tablets of Metronidazole, 10 capsules of Doxycycline, and 10 ml of Dimexidum (the concentrate is added to the last turn).
Dimexidum from cellulitis
Drug possesses vasodilating action and promotes recovery of metabolic processes in all organism that allows to use for fight against cellulitis. For reduction of "orange-peel" means is used in the form of applications and compresses, previously having mixed with the distilled water. Optimum proportions are selected depending on for what zone drug will be used. For hips the concentrate is parted with water in a proportion 1:1, for area of armpits, a neck and hands — in the ratio 1:20 or 1:10. Then in the gauze moistened in the received solution put to problem zones, cover with polyethylene, warm and leave on skin for 50 minutes. The course is calculated on 12-15 procedures. In cosmetology alginate wrappings with Dimexidum and wrappings with Dimexidum and algas are very popular. Before starting a wrapping, it is recommended to take a warm shower (or a bathtub) and to clear skin a fine-grained srub. Then skin of problem body parts is wiped with the wadded disk impregnated with Dimexidum solution. Women with sensitive skin drug should part one volume of a concentrate in three volumes of the distilled or boiled water. In the absence of an allergy to medicine, it is used in pure form. For processing of legs and a stomach it is enough 1 h a spoon of solution. After drawing Dimexidum in skin rub anticellulite means. When it is absorbed, start alginate preparation. As drug quickly stiffens, it is necessary to prepare it very quickly. The alginate divorced in water is distributed on skin, turned from above in two layers of a foil (food wrap) and a terry towel. Influence time — of 40 minutes till one o'clock. It is not necessary to wash away means after a wrapping. It is rather simple to apply a cosmetic milk or the moisturizing cream on legs and a stomach. By the same principle do also wrappings with seaweed.
Overdose Overdose cases at topical administration in therapeutic doses are not described. Strengthening of dozozavisimy side effects is possible. If after application with Dimexidum or putting gel develops undesirable reactions, washes out the damaged place to remove the remains of a dimetisulfoksid, and drug stops treatment.
Interaction DMSO increases absorption and strengthens effects of some other drugs (including insulin) and ethanol. Let's combine with NPVP, antibacterial drugs, heparin. Increases sensitivity of microflora to a beta laktamnym to antibiotics and aminoglycosides, rifampicin, chloramphenicol, griseofulvin. Sensibilizes an organism to means for the general anesthesia.
Terms of sale Without recipe.
Storage conditions To store in the dry, svetozashchishchenny place at a temperature up to 25 °C.
Period of validity For a concentrate — three years. For gel — two years.
Special instructions Some patients catch a garlic smell in the inhaled air. For definition of possible individual intolerance of drug before its use it is recommended to carry out medicinal test (solution is applied on skin and look at reaction of the patient). The testimony of hypersensitivity are the itch and sharp reddening of an integument. If during treatment by Dimexidum the patient has allergic reactions, he should appoint antihistaminic drug.
Not medical use of drug or how to purify polyurethane foam?
One of few known properties of Dimexidum is its ability to well clean the stiffened polyurethane foam. For this purpose the concentrate should be applied on a cotton plug or a sponge, to rub it in a surface on which foam got and to wait several minutes until foam begins to become covered by well exfoliating crust. In need of manipulation repeat several times. It is necessary to work in rubber gloves not to burn skin of hands.
Than to treat a burn for Dimexidum?
It is possible to get burn from Dimexidum at the wrong cultivation of drug, and also at its use in an undiluted look. Burn photo Dimexidum:
What to do at a burn? Well calms the angry skin the cabbage leaf attached to the burned place (from above it can be recorded a bandage). Also for reduction of pain the struck place can be greased with the starch divorced in water of room temperature, a liquid chlorophyll, sea-buckthorn oil, Panthenol. In case of a severe burn it is possible to use ointment with GKS (A hydrocortisone or Prednisolonum).
Analogs Coincidence on the ATH code of the 4th level:
Apizartron
Menovasinum
Apitoxin
Gevkamen
Menthol oil
Alflutop
Turpentine zhivichny
Kapsikam
Synonyms: Dimeksid-Lugal, Dimexidum Zhff, Dimethyl sulfoxide. Analogs with the similar mechanism of action: Alvipsal, Apifor, Artran, Boromentholum, Viprosal, Bile medical, Diklogen, Camphoric alcohol, Camphor (ointment/oil), Kapsikam, Karmolis, Kolkhuri, Kim, Mataren, Ointment Kuznetsova, Pikhtanol, Revma-gel, Hondroksid, Chonsuridum, Chondroitin, Espol, Eftimetatsin.
Zdravzona Dimexidum of 100 ml fl. / Tatkhimfarmpreparaty/Tatkhimfarmpreparata of joint stock company
to show still Dimexidum of 100 ml fl. (Tula f/f) Tula pharmaceutical factory of Ltd company
Apteka24
Dimexidum gel for external use of 25% 30gfarmamed/Suplement Dimexidum ml liquid 50 flakonlubnyfarm (Ukraine, Lubna)
Drugstore of IFC
Dimexidum solution for external use 50mlzhitomirskaya FF (Ukraine, Zhytomyr) BIOSPHERE Dimexidum solution of outside 100 ml, Tula FF (Tula) Russia Dimeksidlubnyfarm Dimexidum of 50 ml flacon solution. (Ukraine, Lubna) Dimexidum gel of 25% 30 g, Farmamed Ooorossiya Galichfarm (Ukraine) Dimeksidgalichfarm to show still Dimexidum of 100 ml konts. for solution for an external comment
(Ukraine, Lviv) Dimexidum solution of outside 100 ml, Tatkhimfarmpreparata (Kazan) of JSC Marbiofarm (Russia) Russia Section: Others Anesthetics Dimexidum 100mllugansky HFZ (Ukraine, Luhansk)
Paniapteka PAY ATTENTION! Dimexidum 50mllugansky HFZ Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Dimexidum surely consult with the attending physician. Dimexidum 50mllugansky HFZ Dimexidum 50mllugansky HFZ Dimexidum 50mllugansky HFZ
Zofloks
Sodium tetraborate in glycerin
About Aknekutana at forums
Propanorm
Retabolil
All materials presented on the website have exclusively help and fact-finding character and cannot be considered as the method of treatment appointed by the doctor or sufficient consultation. Administration of the website and authors of articles do not bear responsibility for any losses and effects which can arise when using materials of the website.
Medical portal medicalmed.us ©
Tizol