hydrochloric acid | HCl - PubChem [PDF]

These cells contain an extensive secretory network (called canaliculi) from which the HCl is secreted into the lumen of

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NIH



U.S. National Library of Medicine



National Center for Biotechnology Information

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Search Compounds

CHEM ISTRY D A T A B A S E

Compound Summary for CID 313

Hydrochloric Acid STRUCTURE

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PHARMACOLOGY

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LITERATURE

PATENTS

BIOACTIVITIES

PubChem CID:

313

Chemical Names:

Hydrochloric acid; Hydrogen chloride; Muriatic acid; 7647-01-0; Chlorohydric acid; Acide chlorhydrique More...

Molecular Formula:

HCl or ClH

Molecular Weight:

36.458 g/mol

InChI Key:

VEXZGXHMUGYJMC-UHFFFAOYSA-N

Drug Information: Safety Summary:

Therapeutic Uses Clinical Trials FDA UNII Laboratory Chemical Safety Summary (LCSS)

Hydrochloric acid is a strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE. from MeSH Hydrochloric acid constitutes the majority of gastric acid, the human digestive fluid. In a complex process and at a large energetic burden, it is secreted by parietal cells (also known as oxyntic cells). These cells contain an extensive secretory network (called canaliculi) from which the HCl is secreted into the lumen of the stomach. They are part of the epithelial fundic glands (also known as oxyntic glands) in the stomach. The chemical compound hydrochloric acid is the aqueous (water-based) solution of hydrogen chloride gas (HCl). It is a strong acid, the major component of gastric acid and of wide industrial use. Hydrochloric acid must be handled with appropriate safety precautions because it is a highly corrosive liquid. Hydrochloric acid, or muriatic acid by its historical but still occasionally used name, has been an important and frequently used chemical from early history and was discovered by the alchemist Jabir ibn Hayyan around the year 800. Hydrogen chloride, also known under the name HCl, is a highly corrosive and toxic colorless gas that forms white fumes on contact with humidity. These fumes consist of hydrochloric acid which forms when hydrogen chloride dissolves in water. The hydrogen chloride molecule HCl is a simple diatomic molecule consisting of a hydrogen atom H and a chlorine atom Cl connected with a covalent single bond. Since the chlorine atom is much more electronegative than the hydrogen atom, the covalent bond between the atoms is quite polar. Hydrogen chloride forms corrosive hydrochloric acid on contact with body tissue. Inhalation of the fumes can cause coughing, choking, inflammation of the nose, throat, and upper respiratory tract, and in severe cases, pulmonary edema, circulatory system failure, and death. Skin contact can cause redness, pain, and severe skin burns. Hydrogen chloride may cause severe burns to the eye and permanent eye damage. Metabolite Description from Human Metabolome Database (HMDB) Hydrochloric acid has many uses. It is used in the production of chlorides, fertilizers, and dyes, in electroplating, and in the photographic, textile, and rubber industries. Hydrochloric acid is corrosive to the eyes, skin, and mucous membranes. Acute (short-term) inhalation exposure may cause eye, nose, and respiratory tract irritation and inflammation and pulmonary edema in humans. Acute oral exposure may cause corrosion of the mucous membranes, esophagus, and stomach and dermal contact may produce severe burns, ulceration, and scarring in humans. Chronic (longterm) occupational exposure to hydrochloric acid has been reported to cause gastritis, chronic bronchitis, dermatitis, and photosensitization in workers. Prolonged exposure to low concentrations may also cause dental discoloration and erosion. EPA has not classified hydrochloric acid for carcinogenicity. Hazards Summary from EPA Air Toxics PUBCHEM

COMPOUND

HYDROCHLORIC ACID

Modify Date: 2018-04-14; Create Date: 2004-09-16

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