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Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a us

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17 April 2018

Impact factor

2.399

Home Index & Ranking Current Issue Archive Cover Images Author Info Submit Editorial Board Special Issues Contact Theranostics Journal of Cancer International Journal of Biological Sciences Journal of Genomics Journal of Bone and Joint Infection (JBJI) Oncomedicine Journal of Biomedicine Nanotheranostics

Research Paper Inhibition of CRL-NEDD8 pathway as a new approach to enhance ATRA-induced differentiation of acute promyelocytic leukemia cells Shuyuan Liu, Jinhua Wan, Yunyuan Kong, Yonglu Zhang, Lagen Wan, Zhanglin Zhang Int. J. Med. Sci. 2018; 15(7): 674-681. doi:10.7150/ijms.23782 [Abstract] [Full text] [PDF] Research Paper ICOS signal facilitates Foxp3 transcription to favor suppressive function of regulatory T cells Qianmei Chen, Lijun Mo, Xiangsheng Cai, Lili Wei, Zhengneng Xie, Hongwei Li, Jinlong Li, Zhiming Hu Int. J. Med. Sci. 2018; 15(7): 666-673. doi:10.7150/ijms.23940 [Abstract] [Full text] [PDF] Review New Trends in the Therapeutic Approach to Metastatic Colorectal Cancer Julia Sánchez-Gundín, Ana María Fernández-Carballido, Lidia Martínez-Valdivieso, Dolores Barreda-Hernández, Ana Isabel Torres-Suárez Int. J. Med. Sci. 2018; 15(7): 659-665. doi:10.7150/ijms.24453 [Abstract] [Full text] [PDF] Research Paper Impact of matrix metalloproteinase-11 gene polymorphisms upon the development and progression of hepatocellular carcinoma Bin Wang, Chin-Jung Hsu, Hsiang-Lin Lee, Chia-Hsuan Chou, Chen-Ming Su, Shun-Fa Yang, Chih-Hsin Tang Int. J. Med. Sci. 2018; 15(6): 653-658. doi:10.7150/ijms.23733 [Abstract] [Full text] [PDF] Research Paper Verteporfin inhibits YAP-induced bladder cancer cell growth and invasion via Hippo signaling pathway Liang Dong, Fan Lin, Wanjun Wu, Yuchen Liu, Weiren Huang Int. J. Med. Sci. 2018; 15(6): 645-652. doi:10.7150/ijms.23460 [Abstract] [Full text] [PDF] Research Paper AMACR overexpression acts as a negative prognostic factor in oral squamous cell carcinoma Hong-Lin He, Ying-En Lee, Min-Te Chang, Yow-Ling Shiue, Shih-Lun Chang, Tzu-Ju Chen, Chang-Ta Chiu Int. J. Med. Sci. 2018; 15(6): 638-644. doi:10.7150/ijms.23291 [Abstract] [Full text] [PDF] Research Paper Resveratrol attenuates denervation-induced muscle atrophy due to the blockade of atrogin-1 and p62 accumulation Yuka Asami, Miki Aizawa, Masakazu Kinoshita, Junji Ishikawa, Kunihiro Sakuma Int. J. Med. Sci. 2018; 15(6): 628-637. doi:10.7150/ijms.22723 [Abstract] [Full text] [PDF] Research Paper Anti-biofilm and Anti-Virulence Efficacy of Celastrol Against Stenotrophomonas maltophilia Hye-Rim Kim, Dongsup Lee, Yong-Bin Eom Int. J. Med. Sci. 2018; 15(6): 617-627. doi:10.7150/ijms.23924 [Abstract] [Full text] [PDF] Research Paper Potential miRNA-target interactions for the screening of gastric carcinoma development in gastric adenoma/dysplasia Yu Jin Kim, Ki-Chul Hwang, Sang Woo Kim, Yong Chan Lee Int. J. Med. Sci. 2018; 15(6): 610-616. doi:10.7150/ijms.24061 [Abstract] [Full text] [PDF] Research Paper Glucagon-Like Peptide-1 Receptor Agonist and Glucagon Increase Glucose-Stimulated Insulin Secretion in Beta Cells via Distinct Adenylyl Cyclases Young-Sun Lee, Hee-Sook Jun Int. J. Med. Sci. 2018; 15(6): 603-609. doi:10.7150/ijms.24492 [Abstract] [Full text] [PDF] Research Paper Lipopolysaccharide Mediates the Destruction of Intercellular Tight Junction among Renal Tubular Epithelial Cells via RhoT1/SMAD-4/JAM-3 Pathway Shixiang Zheng, Zhuoyong Lin, Zhongwei Liu, Yipeng Liu, Wenwei Wu Int. J. Med. Sci. 2018; 15(6): 595-602. doi:10.7150/ijms.23786 [Abstract] [Full text] [PDF] Research Paper Single nucleotide polymorphisms and haplotypes of carbonic anhydrase 9 can predict invasive squamous cell carcinoma of uterine cervix Huang-Pin Shen, Yi-Hsuan Hsiao, Shun-Fa Yang, Yu-Fan Liu, Jiunn-Liang Ko, Po-Hui Wang Int. J. Med. Sci. 2018; 15(6): 587-594. doi:10.7150/ijms.23359 [Abstract] [Full text] [PDF] Research Paper HMGB1 genetic polymorphisms are biomarkers for the development and progression of breast cancer Bi-Fei Huang, Huey-En Tzeng, Po-Chun Chen, Chao-Qun Wang, Chen-Ming Su, Yan Wang, Gui-Nv Hu, YongMing Zhao, Qian Wang, Chih-Hsin Tang Int. J. Med. Sci. 2018; 15(6): 580-586. doi:10.7150/ijms.23462 [Abstract] [Full text] [PDF]

ISSN 1449-1907

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Indexed in MEDLINE, PubMed, EMBASE, CAS/Chemical Abstracts, CAB Abstracts, Scopus, Science Citation Index (SCI) Expanded .... Full texts of articles appear in PubMed Central and Europe PMC. (For NIH-funded researchers) Save time by submitting your paper to us - this journal is in full compliance with NIH Public Access Requirement. This Journal is ranked very well according to SCImago in the area of Medicine ...details

Impact factor is 2.399 according to 2017 release of Journal Citation Reports®. Cover suggestion: Authors are encouraged to submit high quality, eye catching illustrations or images for consideration as the issue covers of the journal. ...details

Top cited papers: Laxmaiah Manchikanti et al. Evaluation of Lumbar Facet Joint Nerve Blocks in Managing Chronic Low Back Pain: A Randomized, Double-Blind, Controlled Trial with a 2-Year Follow-Up. Cited by 95 DS O'Mahony et al. Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages. Cited by 79 Naomi Brooks et al. Strength training improves muscle quality and insulin sensitivity in Hispanic older adults with type 2 diabetes. Cited by 146 Chikako Kiyohara1 & Kouichi Yoshimasu. Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis. Cited by 137 SL Chen & TR Morgan. The Natural History of Hepatitis C Virus (HCV) Infection. Cited by 283 Vector delivery is still a bottleneck for gene therapy. To overcome some disadvantages of adenoviral and retroviral vectors, we developed a hybrid vector. This hybrid vector, AdLTR-luc, was created by adding two elements from Moloney murine leukemia virus (MoMLV) flanking the luciferase cDNA into an E1/E3-deleted, replication deficient serotype 5 adenovirus vector (Zheng et al., Nature Biotechnol, 2000), and demonstrated that the MoMLV element upstream of the luciferase cDNA was broken during the integration event. The purpose of the current study was to determine if the MoMLV element downstream of the luciferase cDNA was also broken when integration occurred. We used the same A5 cell clones (#10 and 11) from the earlier the paper along with restriction endonuclease digestions, plus Southern hybridization, and PCR. Southern hybridization indicated that the luciferase cDNA was intact in the cloned cells. Results from Xho I and Sal I digestions showed that integration occurred in cloned cells. ...details Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during wound repair. VEGF is estrogen responsive and capable of regulating its own receptor, vascular endothelial growth factor receptor-2 (VEGFR-2). Several agricultural pesticides (e.g., methoxychlor) have estrogenic potential that can initiate inappropriate physiological responses in estrogenic-sensitive tissues following exposure in vivo. Thus, the current study was designed to determine whether the VEGFR-2-Luciferase (Luc) reporter transgenic mouse is a useful model for evaluating estrogenic tendencies of methoxychlor by monitoring wound healing via VEGFR-2-mediated gene expression using bioluminescence and real-time imaging technology. ...details A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. This human head surrogate fills the void between Post-Mortem Human Subject testing (with biofidelity but handling restrictions) and commercial ballistic head forms (with no biofidelity but ease of use). This unique human head surrogate is based on refreshed human craniums and surrogate materials representing human head soft tissues such as the skin, dura, and brain. A methodology for refreshing the craniums is developed and verified through material testing. ...details

Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids for the management of axial or discogenic pain in patients without disc herniation, radiculitis, or facet joint pain. Summary of Background Data: Cervical discogenic Research Paper pain without disc herniation is a common cause of suffering Salmonella Overcomes Drug Resistance in Tumor through P-glycoprotein Downregulation and disability in the adult population. Once conservative Chih-Jen Yang, Wen-Wei Chang, Song-Tao Lin, Man-Chin Chen, Che-Hsin Lee management has failed and facet joint pain has been excluded, cervical epidural injections may be considered as a Int. J. Med. Sci. 2018; 15(6): 574-579. doi:10.7150/ijms.23285 management tool. Despite a paucity of evidence, cervical [Abstract] [Full text] [PDF] epidural injections are one of the most commonly performed Research Paper nonsurgical interventions in the management of chronic axial Dehydroepiandrosterone supplementation combined with Weight-Loading Whole-Body Vibration Training or disc-related neck pain....details

(WWBV) affects exercise performance and muscle glycogen storage in middle-aged C57BL/6 mice Yi-Ming Chen, Hao-Chieh Lee, Mu-Tsung Chen, Chi-Chang Huang, Wen-Chyuan Chen Int. J. Med. Sci. 2018; 15(6): 564-573. doi:10.7150/ijms.23352 [Abstract] [Full text] [PDF] Research Paper Vascular calcification and left ventricular hypertrophy in hemodialysis patients: interrelationship and clinical impacts Hyeon Seok Hwang, Jung Sun Cho, Yu Ah Hong, Yoon Kyung Chang, Suk Young Kim, Seok Joon Shin, Hye Eun Yoon Int. J. Med. Sci. 2018; 15(6): 557-563. doi:10.7150/ijms.23700 [Abstract] [Full text] [PDF] More ... Copyright ©2018 Ivyspring International Publisher. Terms of Use & Privacy

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