Know the signs and Symptoms of Xerophthalmia [PDF]

This is a childhood blinding disease which is caused by a lack of. Vitamin A in the diet. Often the first symptom is nig

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Know the signs and Symptoms of Xerophthalmia Xerophthalmia is the term used to describe the eye signs of Vitamin A deficiency

This is a childhood blinding disease which is caused by a lack of Vitamin A in the diet

Fig. 1. Child, 6 years old. Long history of night blindness. Fine Foamy Line of Bitot’s spots

Lid Retractor Wrinkled Conjunctiva

Bitot’s spots Wrinkled Conjunctiva

Fig. 3. Child, 4 years old. Chronic Bitot’s spots with localized xerosis and dark coloring of the conjunctiva

Although Bitot’s spots differ somewhat in size, location and shape, they have similar appearance.

Often the first symptom is night blindness followed by Bitot’s spots on the conjunctiva

Fine line of Bitot’s spots

Conjunctiva

Cornea

Fig. 2. Child, 3 years old. Night blindness and Bitot’s spots existing for months. Wrinkled conjunctiva at corners

Bitot’s spots Bitot’s spots

Reflection from camera flash

They are accumulations of foamy, cheesy material on the conjunctiva, often in association with other signs of xerophthalmia

As the disease progresses the cornea becomes dry and rough. This is known as conjunctival xerosis

Bitot’s spots

Rough Conjunctiva

Fig. 5. Child, 6 years old. Isolated Bitot’s spots with well defined borders.

Bitot’s spots

Bitot’s spots and conjunctival xerosis are characteristic signs of Vitamin A deficiency.

Fig. 4. Child, 10 months old. Cheesy, smooth Bitot’s spots with dark coloring

Foamy Bitot’s spots

Fig. 6. Child, 5 years old. Cheesy Bitot’s spots on both side of the cornea

When these two signs are present in children, there should be no mistake in recognizing the disease.

Drying of the cornea (corneal xerosis) may develop if the disease is not treated.

Fig. 7. Child, 2 years old. Xerosis, wrinkling and dark coloring of the conjunctiva on one side. Cornea dry and dull (xerosis).

Rough dull cornea

Lid retractor Corneal perforation

Fig. 9. Child, 3 year old. Keratomalacia with grayish, jelly like bulging cornea. The iris and lens have pushed forward into the cornea.

As the nutritional status of the child worsens or if the child develops an infectious disease, the cornea may become increasingly damaged

Corneal Xerosis

Conjunctival xerosis

Fig. 8. Child, 1 year old. Rough, dull, opaque cornea with small perforation (hole). A piece of the iris has pushed through the hole.

Bulging Cornea (keratomalacia)

The dryness may quickly give way to softening of the cornea (keratomalacia). Bulging or rupture of the cornea may follow.

BLINDNESS – The result of Vitamin A deficiency.

Shrunken eyeball following keratomalacia

Fig. 11. Child, 4 years old. The child had measles 1 year ago which caused an eye infection. Now, she is left with a central scar on her cornea.

Staphyloma

If Vitamin A deficiency is not treated, or is treated to late, it may result in severe damage and permanent blindness.

Fig. 10. Child, 3 years old. Blind for the last two years. The other eye is also blind.

Central white scar in the cornea

Fig. 12. Child, 4 years old. The cornea is completely scarred and the eye is blind.

A scar of the cornea impairs it’s transparency and interferes with vision. A perforated eye ball shrinks and leads to complete blindness

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