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Procede de stockage de globules rouges a entretien prolonge de concentrations cellulaires d'atp et de diphospho-2,3 glycerate
Publication number Publication type Application number Publication date Filing date Priority date
WO1991004659 A1 Application PCT/US1990/005817 18 Apr 1991 9 Oct 1990 6 Oct 1989
Also published as
DE69032923D1, 4 More »
Inventors
Harold T. Meryman, 2 More »
pouvant être transfusés, consistant à diminuer l'osmolalité effective de la solution
Applicant
American National Red Cross
en suspension, et à augmenter le pH intracellulaire des cellules avant leur
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stockage. L'invention concerne également des procédes permettant d'aumgenter
Patent Citations (1), Non-Patent Citations (2), Referenced by (18), Classifications (6), Legal Events (8)
WO 1991004659 A1 ABSTRACT Procédé amélioré de prolongation de la durée de conservation de globules rouges
le pH intracellulaire. Ces procédés consistent à collecter les cellules dans un anticoagulant à un pH de 7,0 ou plus et/ou à laver, à diluer ou à remettre en
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suspension les cellules avant de les stocker dans une solution tamponnée biologiquement compatible, laquelle contient au moins un anion ou un non-
électrolyte non pénétrant ou sensiblement non pénétrant, et est exempte d'ions de chlorure.
DESCRIPTION available in English CLAIMS available in English PATENT CITATIONS Cited Patent
Filing date
Publication date
Applicant
Title
US4585735 *
19 Jul 1984
29 Apr 1986
American National Red Cross
Prolonged storage of red blood cells
* Cited by examiner
NON-PATENT CITATIONS Reference 1
*
CHEMICAL ABSTRACTS, Vol. 100, issued 1984 (Columbus, Ohio, USA) MUELLER et al. "The Kinetics of the chloride-pH equilibration in human red blood cells", See page 371 col. 2, Abstract No. 207088P Biomed. Biochim. Acta 1984, 43(1) 77-83 (Eng.).
2
*
See also references of EP0494957A4
* Cited by examiner
REFERENCED BY Citing Patent
Filing date
Publication date
Applicant
Title
EP1082006A1 *
26 May 1999
14 Mar 2001
Lifecell Corporation
Cryoconservation amelioree d'erythrocytes humains
EP1082006A4 *
26 May 1999
11 Sep 2002
Lifecell Corp
Cryoconservation amelioree d'erythrocytes humains
US5906915 *
31 Oct 1996
25 May 1999
Baxter International Inc.
Method for storing red cells using reduced citrate anticoagulant and a solution containing sodium, citrate, phosphate, adenine and mannitol
US8535421
8 Oct 2010
17 Sep 2013
New Health Sciences, Inc.
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US8569052
25 May 2011
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New Health Sciences, Inc.
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US8828226
14 Apr 2009
9 Sep 2014
The Trustees Of Boston University
System for assessing the efficacy of stored red blood cells using microvascular networks
US8895236
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Stephen A. Livesey
Composition for cryopreservation comprising nicotinamide, glycerol and red blood cells
US9005343
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US9067004
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US9095662
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Blood storage bag system and depletion devices with oxygen and carbon dioxide depletion capabilities Fuel injection system with high repeatability and stability of operation for an internal-combustion engine
US9140223
23 Nov 2009
22 Sep 2015
C.R.F. SOCIETá CONSORTILE PER AZIONI
US9199016
3 Jul 2012
1 Dec 2015
New Health Sciences, Inc.
System for extended storage of red blood cells and methods of use
US9296990
26 Sep 2013
29 Mar 2016
New Health Sciences, Inc.
Oxygen depletion devices and methods for removing oxygen from red blood cells
US9314014
17 Feb 2005
19 Apr 2016
University Of Maryland, Baltimore
Compositions and methods for the storage of red blood cells Methods and materials for prolonging useful storage of red blood cell preparations and platelet preparations
US9315775
18 Jun 2014
19 Apr 2016
Mayo Foundation For Medical Education And Research
US9339025
25 Aug 2011
17 May 2016
New Health Sciences, Inc.
Method for enhancing red blood cell quality and survival during storage
US9539375
2 Mar 2015
10 Jan 2017
New Health Sciences, Inc.
Integrated leukocyte, oxygen and/or CO2 depletion, and plasma separation filter device
US9801784
31 Mar 2017
31 Oct 2017
New Health Sciences, Inc.
Anaerobic blood storage containers
* Cited by examiner
CLASSIFICATIONS International Classification
A61K35/14, A01N1/02
Cooperative Classification
A01N1/0226, A01N1/02
European Classification
A01N1/02, A01N1/02C2P
LEGAL EVENTS Date
Code
Event
18 Apr 1991
AK
Designated states
18 Apr 1991
AL
Designated countries for regional patents
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