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The Centre for Phenogenomics

The Centre for Phenogenomics

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Publications Publications made possible by The Centre for Phenogenomics

2017 Allemang-Grand, R., J. Ellegood, L. Spencer Noakes, J. Ruston, M. Justice, B. J. Nieman and J. P. Lerch (2017). "Neuroanatomy in mouse models of Rett syndrome is related to the severity of Mecp2 mutation and behavioral phenotypes." Mol Autism 8: 32. (co-authored by Mouse Imaging Centre staff) Arbogast, T., G. Iacono, C. Chevalier, N. O. Afinowi, X. Houbaert, M. C. van Eede, C. Laliberte, M. C. Birling, K. Linda, H. Meziane, M. Selloum, T. Sorg, N. Nadif Kasri, D. A. Koolen, H. G. Stunnenberg, R. M. Henkelman, M. Kopanitsa, Y. Humeau, B. B. A. De Vries and Y. Herault (2017). "Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition." PLoS Genet 13(7): e1006886. (co-authored by Mouse Imaging Centre staff) Baht, G. S., P. Nadesan, D. Silkstone and B. A. Alman (2017). "Pharmacologically targeting beta-catenin for NF1 associated deficiencies in fracture repair." Bone 98: 31-36. Baker, Z. N., K. Jett, A. Boulet, A. Hossain, P. A. Cobine, B. E. Kim, A. M. El Zawily, L. Lee, G. F. Tibbits, M. J. Petris and S. C. Leary (2017). "The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart." Hum Mol Genet 26(23): 4617-4628. Baribeau, D. A., A. Dupuis, T. A. Paton, S. W. Scherer, R. J. Schachar, P. D. Arnold, P. Szatmari, R. Nicolson, S. Georgiades, J. Crosbie, J. Brian, A. Iaboni, J. Lerch and E. Anagnostou (2017). "Oxytocin Receptor Polymorphisms are Differentially Associated with Social Abilities across Neurodevelopmental Disorders." Sci Rep 7(1): 11618. (co-authored by Mouse Imaging Centre staff) Bartlett, C. S., R. P. Scott, I. A. Carota, M. L. Wnuk, Y. S. Kanwar, J. H. Miner and S. E. Quaggin (2017). "Glomerular mesangial cell recruitment and function require the co-receptor neuropilin-1." Am J Physiol Renal Physiol 313(6): F1232-F1242. Blanco, A. M., M. Gomez-Boronat, A. L. Alonso-Gomez, R. Yufa, S. Unniappan, M. J. Delgado and A. I. Valenciano (2017). "Characterization of Ghrelin O-Acyltransferase (GOAT) in goldfish (Carassius auratus)." PLoS One 12(2): e0171874. Bolon, B., S. Newbigging and K. L. Boyd (2017). "Pathology Evaluation of Developmental Phenotypes in Neonatal and Juvenile Mice." Curr Protoc Mouse Biol 7(3): 191-219. (co-authored by TCP staff) Boudreau, M., C. L. Tardif, N. Stikov, J. G. Sled, W. Lee and G. B. Pike (2017). "B1 mapping for bias-correction in quantitative T1 imaging of the brain at 3T using standard pulse sequences." J Magn Reson Imaging 46(6): 1673-1682. (co-authored by Mouse Imaging Centre staff) Back To Top Bowl, M. R., M. M. Simon, N. J. Ingham, S. Greenaway, L. Santos, H. Cater, S. Taylor, J. Mason, N. Kurbatova, S. Pearson, L. R. Bower, D. A. Clary, H. Meziane, P. Reilly, O. Minowa, L. Kelsey, C. International Mouse Phenotyping, G. P. Tocchini-Valentini, X. Gao, A. Bradley, W. C. Skarnes, M. Moore, A. L. Beaudet, M. J. Justice, J. Seavitt, M. E. Dickinson, W. Wurst, M. H. de Angelis, Y. Herault, S. Wakana, L. M. J. Nutter, A. M. Flenniken, C. McKerlie, S. A. Murray, K. L. Svenson, R. E. Braun, D. B. West, K. C. K. Lloyd, D. J. Adams, J. White, N. Karp, P. Flicek, D. Smedley, T. F. Meehan, H. E. Parkinson, L. M. Teboul, S. Wells, K. P. Steel, A. M. Mallon and S. D. M. Brown (2017). "A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction." Nat Commun 8(1): 886. (co-authored by TCP staff) Cahill, L. S., J. Bishop, L. M. Gazdzinski, A. Dorr, B. Stefanovic and J. G. Sled (2017). "Altered cerebral blood flow and cerebrovascular function after voluntary exercise in adult mice." Brain Struct Funct 222(8): 3395-3405. (co-authored by Mouse Imaging Centre staff) Cahill, L. S., L. M. Gazdzinski, A. K. Tsui, Y. Q. Zhou, S. Portnoy, E. Liu, C. D. Mazer, G. M. Hare, A. Kassner and J. G. Sled (2017). "Functional and anatomical evidence of cerebral tissue hypoxia in young sickle cell anemia mice." J Cereb Blood Flow Metab 37(3): 994-1005. (coauthored by Mouse Imaging Centre staff) Cahill, L. S., M. Y. Rennie, J. Hoggarth, L. X. Yu, A. Rahman, J. C. Kingdom, M. Seed, C. K. Macgowan and J. G. Sled (2017). "Feto- and uteroplacental vascular adaptations to chronic maternal hypoxia in the mouse." J Physiol. (co-authored by Mouse Imaging Centre staff) Calamita, P., A. Miluzio, A. Russo, E. Pesce, S. Ricciardi, F. Khanim, C. Cheroni, R. Alfieri, M. Mancino, C. Gorrini, G. Rossetti, I. Peluso, M. Pagani, D. L. Medina, J. Rommens and S. Biffo (2017). "SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention." PLoS Genet 13(1): e1006552. Capurro, M., T. Izumikawa, P. Suarez, W. Shi, M. Cydzik, T. Kaneiwa, J. Gariepy, L. Bonafe and J. Filmus (2017). "Glypican-6 promotes the growth of developing long bones by stimulating Hedgehog signaling." J Cell Biol 216(9): 2911-2926. Chi, L., A. Ahmed, A. R. Roy, S. Vuong, L. S. Cahill, L. Caporiccio, J. G. Sled, I. Caniggia, M. D. Wilson and P. Delgado-Olguin (2017). "G9a controls placental vascular maturation by activating the Notch Pathway." Development 144(11): 1976-1987. (co-authored by Mouse Imaging Centre staff) Back To Top Du Toit, E., L. Browne, H. Irving-Rodgers, H. M. Massa, N. Fozzard, M. P. Jennings and I. R. Peak (2017). "Effect of GPR84 deletion on obesity and diabetes development in mice fed long chain or medium chain fatty acid rich diets." Eur J Nutr. El-Hassan, A. R., V. Leung, F. Kharfallah, M. C. Guyot, R. Allache, P. Gros and Z. Kibar (2017). "Identification and characterization of a novel chemically induced allele at the planar cell polarity gene Vangl2." Mamm Genome. Farah, O., S. Biechele, J. Rossant and D. Dufort (2017). "Porcupine-dependent Wnt signaling controls stromal proliferation and endometrial gland maintenance through the action of distinct WNTs." Dev Biol 422(1): 58-69. Farkona, S., A. Soosaipillai, P. Filippou, D. Korbakis, S. Serra, F. Ruckert, E. P. Diamandis and I. M. Blasutig (2017). "Generation of monoclonal antibodies and development of an immunofluorometric assay for the detection of CUZD1 in tissues and biological fluids." Clin Biochem 50(18): 1168-1174. Feldcamp, L. A., P. C. Boutros, R. Raymond, P. J. Fletcher, J. N. Nobrega and A. H. C. Wong (2017). "Pdxdc1 modulates prepulse inhibition of acoustic startle in the mouse." Transl Psychiatry 7(5): e1125. Fernandes, D. J., J. Ellegood, R. Askalan, R. D. Blakely, E. Dicicco-Bloom, S. E. Egan, L. R. Osborne, C. M. Powell, A. Raznahan, D. M. Robins, M. W. Salter, A. S. Sengar, J. Veenstra-VanderWeele, R. M. Henkelman and J. P. Lerch (2017). "Spatial gene expression analysis of neuroanatomical differences in mouse models." Neuroimage 163: 220-230. (co-authored by Mouse Imaging Centre staff) Filippou, P., D. Korbakis, S. Farkona, A. Soosaipillai, T. Karakosta and E. P. Diamandis (2017). "A new enzyme-linked immunosorbent assay (ELISA) for human free and bound kallikrein 9." Clin Proteomics 14: 4. Geyer, S. H., L. Reissig, J. Rose, R. Wilson, F. Prin, D. Szumska, R. Ramirez-Solis, C. Tudor, J. White, T. J. Mohun and W. J. Weninger (2017). "A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5)." J Anat 230(5): 710-719. Ghugre, N. R., M. Pop, R. Thomas, S. Newbigging, X. Qi, J. Barry, B. H. Strauss and G. A. Wright (2017). "Hemorrhage promotes inflammation and myocardial damage following acute myocardial infarction: insights from a novel preclinical model and cardiovascular magnetic resonance." J Cardiovasc Magn Reson 19(1): 50. (co-authored by TCP staff) Gomez-Velazquez, M., C. Badia-Careaga, A. V. Lechuga-Vieco, R. Nieto-Arellano, J. J. Tena, I. Rollan, A. Alvarez, C. Torroja, E. F. Caceres, A. R. Roy, N. Galjart, P. Delgado-Olguin, F. Sanchez-Cabo, J. A. Enriquez, J. L. Gomez-Skarmeta and M. Manzanares (2017). "CTCF counterregulates cardiomyocyte development and maturation programs in the embryonic heart." PLoS Genet 13(8): e1006985. Back To Top Gompers, A. L., L. Su-Feher, J. Ellegood, N. A. Copping, M. A. Riyadh, T. W. Stradleigh, M. C. Pride, M. D. Schaffler, A. A. Wade, R. Catta-Preta, I. Zdilar, S. Louis, G. Kaushik, B. J. Mannion, I. Plajzer-Frick, V. Afzal, A. Visel, L. A. Pennacchio, D. E. Dickel, J. P. Lerch, J. N. Crawley, K. S. Zarbalis, J. L. Silverman and A. S. Nord (2017). "Germline Chd8 haploinsufficiency alters brain development in mouse." Nat Neurosci 20(8): 1062-1073. (co-authored by Mouse Imaging Centre staff) Gu, B., J. P. Lambert, K. Cockburn, A. C. Gingras and J. Rossant (2017). "AIRE is a critical spindle-associated protein in embryonic stem cells." Elife 6. Hall, E. A., M. S. Nahorski, L. M. Murray, R. Shaheen, E. Perkins, K. N. Dissanayake, Y. Kristaryanto, R. A. Jones, J. Vogt, M. Rivagorda, M. T. Handley, G. R. Mali, T. Quidwai, D. C. Soares, M. A. Keighren, L. McKie, R. L. Mort, N. Gammoh, A. Garcia-Munoz, T. Davey, M. Vermeren, D. Walsh, P. Budd, I. A. Aligianis, E. Faqeih, A. J. Quigley, I. J. Jackson, Y. Kulathu, M. Jackson, R. R. Ribchester, A. von Kriegsheim, F. S. Alkuraya, C. G. Woods, E. R. Maher and P. Mill (2017). "PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins." Am J Hum Genet 100(5): 706-724. Heyn, C. C., J. Bishop, K. Duffin, W. Lee, J. Dazai, S. Spring, B. J. Nieman and J. G. Sled (2017). "Magnetic resonance thermometry of flowing blood." NMR Biomed 30(11). (co-authored by Mouse Imaging Centre staff) Hoang, B., M. J. Ernsting, W. S. Tang, J. Bteich, E. Undzys, T. Kiyota and S. D. Li (2017). "Cabazitaxel-conjugated nanoparticles for docetaxelresistant and bone metastatic prostate cancer." Cancer Lett 410: 169-179. Huang, J., A. Khan, B. C. Au, D. L. Barber, L. Lopez-Vasquez, N. L. Prokopishyn, M. Boutin, M. Rothe, J. W. Rip, M. Abaoui, M. S. Nagree, S. Dworski, A. Schambach, A. Keating, M. L. West, J. Klassen, P. V. Turner, S. Sirrs, C. A. Rupar, C. Auray-Blais, R. Foley and J. A. Medin (2017). "Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34(+) Cells for Correction of Fabry Disease." Mol Ther Methods Clin Dev 5: 241-258. Jamsai, D., D. N. Watkins, A. E. O'Connor, D. J. Merriner, S. Gursoy, A. D. Bird, B. Kumar, A. Miller, T. J. Cole, B. J. Jenkins and M. K. O'Bryan (2017). "In vivo evidence that RBM5 is a tumour suppressor in the lung." Sci Rep 7(1): 16323. Jang, J. Y., S. Y. Choi, I. Park, D. Y. Park, K. Choe, P. Kim, Y. K. Kim, B. J. Lee, M. Hirashima, Y. Kubota, J. W. Park, S. Y. Cheng, A. Nagy, Y. J. Park, K. Alitalo, M. Shong and G. Y. Koh (2017). "VEGFR2 but not VEGFR3 governs integrity and remodeling of thyroid angiofollicular unit in normal state and during goitrogenesis." EMBO Mol Med 9(6): 750-769. Back To Top Johnson, L., B. Ganss, A. Wang, R. A. Zirngibl, D. E. Johnson, C. Owen, G. Bradley and I. Voronov (2017). "V-ATPases Containing a3 Subunit Play a Direct Role in Enamel Development in Mice." J Cell Biochem 118(10): 3328-3340. (co-authored by TCP staff) Joo, I. L., A. Y. Lai, P. Bazzigaluppi, M. M. Koletar, A. Dorr, M. E. Brown, L. A. Thomason, J. G. Sled, J. McLaurin and B. Stefanovic (2017). "Early neurovascular dysfunction in a transgenic rat model of Alzheimer's disease." Sci Rep 7: 46427. (co-authored by Mouse Imaging Centre staff) Kalin, A. M., M. T. Park, M. M. Chakravarty, J. P. Lerch, L. Michels, C. Schroeder, S. D. Broicher, S. Kollias, R. M. Nitsch, A. F. Gietl, P. G. Unschuld, C. Hock and S. E. Leh (2017). "Subcortical Shape Changes, Hippocampal Atrophy and Cortical Thinning in Future Alzheimer's Disease Patients." Front Aging Neurosci 9: 38. (co-authored by Mouse Imaging Centre staff) Karp, N. A., J. Mason, A. L. Beaudet, Y. Benjamini, L. Bower, R. E. Braun, S. D. M. Brown, E. J. Chesler, M. E. Dickinson, A. M. Flenniken, H. Fuchs, M. H. Angelis, X. Gao, S. Guo, S. Greenaway, R. Heller, Y. Herault, M. J. Justice, N. Kurbatova, C. J. Lelliott, K. C. K. Lloyd, A. M. Mallon, J. E. Mank, H. Masuya, C. McKerlie, T. F. Meehan, R. F. Mott, S. A. Murray, H. Parkinson, R. Ramirez-Solis, L. Santos, J. R. Seavitt, D. Smedley, T. Sorg, A. O. Speak, K. P. Steel, K. L. Svenson, C. International Mouse Phenotyping, S. Wakana, D. West, S. Wells, H. Westerberg, S. Yaacoby and J. K. White (2017). "Prevalence of sexual dimorphism in mammalian phenotypic traits." Nat Commun 8: 15475. (co-authored by TCP staff) Kazazian, K., C. Go, H. Wu, O. Brashavitskaya, R. Xu, J. W. Dennis, A. C. Gingras and C. J. Swallow (2017). "Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton." Cancer Res 77(2): 434-447. Kim, D. Y., J. Yu, R. K. Mui, R. Niibori, H. B. Taufique, R. Aslam, J. W. Semple and S. P. Cordes (2017). "The tyrosine kinase receptor Tyro3 enhances lifespan and neuropeptide Y (Npy) neuron survival in the mouse anorexia (anx) mutation." Dis Model Mech 10(5): 581-595. Kim, K. H., Y. H. Kim, J. E. Son, J. H. Lee, S. Kim, M. S. Choe, J. H. Moon, J. Zhong, K. Fu, F. Lenglin, J. A. Yoo, P. J. Bilan, A. Klip, A. Nagy, J. R. Kim, J. G. Park, S. M. Hussein, K. O. Doh, C. C. Hui and H. K. Sung (2017). "Intermittent fasting promotes adipose thermogenesis and metabolic homeostasis via VEGF-mediated alternative activation of macrophage." Cell Res 27(11): 1309-1326. Kishimoto, K., J. Nomura, J. Ellegood, K. Fukumoto, J. P. Lerch, D. Moreno-De-Luca, T. Bourgeron, K. Tamada and T. Takumi (2017). "Behavioral and neuroanatomical analyses in a genetic mouse model of 2q13 duplication." Genes Cells 22(5): 436-451. (co-authored by Mouse Imaging Centre staff) Back To Top Korbakis, D., A. Soosaipillai and E. P. Diamandis (2017). "Study of kallikrein-related peptidase 6 (KLK6) and its complex with alpha1-antitrypsin in biological fluids." Clin Chem Lab Med 55(9): 1385-1396. Lai, M. C., J. P. Lerch, D. L. Floris, A. N. Ruigrok, A. Pohl, M. V. Lombardo and S. Baron-Cohen (2017). "Imaging sex/gender and autism in the brain: Etiological implications." J Neurosci Res 95(1-2): 380-397. (co-authored by Mouse Imaging Centre staff) Lee, J., J. Koehler, B. Yusta, J. Bahrami, D. Matthews, M. Rafii, P. B. Pencharz and D. J. Drucker (2017). "Enteroendocrine-derived glucagon-like peptide-2 controls intestinal amino acid transport." Mol Metab 6(3): 245-255. Leibinger, M., A. Andreadaki, R. Golla, E. Levin, A. M. Hilla, H. Diekmann and D. Fischer (2017). "Boosting CNS axon regeneration by harnessing antagonistic effects of GSK3 activity." Proc Natl Acad Sci U S A 114(27): E5454-E5463. Lerch, J. P., A. J. van der Kouwe, A. Raznahan, T. Paus, H. Johansen-Berg, K. L. Miller, S. M. Smith, B. Fischl and S. N. Sotiropoulos (2017). "Studying neuroanatomy using MRI." Nat Neurosci 20(3): 314-326. (co-authored by Mouse Imaging Centre staff) Lindqvist, J., E. Torvaldson, J. Gullmets, H. Karvonen, A. Nagy, P. Taimen and J. E. Eriksson (2017). "Nestin contributes to skeletal muscle homeostasis and regeneration." J Cell Sci 130(17): 2833-2842. Logie, J., A. N. Ganesh, A. M. Aman, R. S. Al-Awar and M. S. Shoichet (2017). "Preclinical evaluation of taxane-binding peptide-modified polymeric micelles loaded with docetaxel in an orthotopic breast cancer mouse model." Biomaterials 123: 39-47. Matsumoto, Y., J. La Rose, M. Lim, H. A. Adissu, N. Law, X. Mao, F. Cong, P. Mera, G. Karsenty, D. Goltzman, A. Changoor, L. Zhang, M. Stajkowski, M. D. Grynpas, C. Bergmann and R. Rottapel (2017). "Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism." J Clin Invest 127(7): 2612-2625. (co-authored by TCP staff) Back To Top Meehan, T. F., N. Conte, D. B. West, J. O. Jacobsen, J. Mason, J. Warren, C. K. Chen, I. Tudose, M. Relac, P. Matthews, N. Karp, L. Santos, T. Fiegel, N. Ring, H. Westerberg, S. Greenaway, D. Sneddon, H. Morgan, G. F. Codner, M. E. Stewart, J. Brown, N. Horner, C. International Mouse Phenotyping, M. Haendel, N. Washington, C. J. Mungall, C. L. Reynolds, J. Gallegos, V. Gailus-Durner, T. Sorg, G. Pavlovic, L. R. Bower, M. Moore, I. Morse, X. Gao, G. P. Tocchini-Valentini, Y. Obata, S. Y. Cho, J. K. Seong, J. Seavitt, A. L. Beaudet, M. E. Dickinson, Y. Herault, W. Wurst, M. H. de Angelis, K. C. K. Lloyd, A. M. Flenniken, L. M. J. Nutter, S. Newbigging, C. McKerlie, M. J. Justice, S. A. Murray, K. L. Svenson, R. E. Braun, J. K. White, A. Bradley, P. Flicek, S. Wells, W. C. Skarnes, D. J. Adams, H. Parkinson, A. M. Mallon, S. D. M. Brown and D. Smedley (2017). "Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium." Nat Genet 49(8): 12311238. (co-authored by TCP staff) Mishra, N., P. Wang, D. Goldsmith, X. Zhao, Y. Xue, U. Christians and B. A. Minassian (2017). "Everolimus does not prevent Lafora body formation in murine Lafora disease." Neurol Genet 3(1): e127. Moffitt, A. B., S. L. Ondrejka, M. McKinney, R. E. Rempel, J. R. Goodlad, C. H. Teh, S. Leppa, S. Mannisto, P. E. Kovanen, E. Tse, R. K. H. AuYeung, Y. L. Kwong, G. Srivastava, J. Iqbal, J. Yu, K. Naresh, D. Villa, R. D. Gascoyne, J. Said, M. B. Czader, A. Chadburn, K. L. Richards, D. Rajagopalan, N. S. Davis, E. C. Smith, B. C. Palus, T. J. Tzeng, J. A. Healy, P. L. Lugar, J. Datta, C. Love, S. Levy, D. B. Dunson, Y. Zhuang, E. D. Hsi and S. S. Dave (2017). "Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2." J Exp Med 214(5): 1371-1386. Moreira, S., E. Polena, V. Gordon, S. Abdulla, S. Mahendram, J. Cao, A. Blais, G. A. Wood, A. Dvorkin-Gheva and B. W. Doble (2017). "A Single TCF Transcription Factor, Regardless of Its Activation Capacity, Is Sufficient for Effective Trilineage Differentiation of ESCs." Cell Rep 20(10): 2424-2438. Nitschke, F., M. A. Sullivan, P. Wang, X. Zhao, E. E. Chown, A. M. Perri, L. Israelian, L. Juana-Lopez, P. Bovolenta, S. Rodriguez de Cordoba, M. Steup and B. A. Minassian (2017). "Abnormal glycogen chain length pattern, not hyperphosphorylation, is critical in Lafora disease." EMBO Mol Med 9(7): 906-917. Nosi, U., F. Lanner, T. Huang and B. Cox (2017). "Overexpression of Trophoblast Stem Cell-Enriched MicroRNAs Promotes Trophoblast Fate in Embryonic Stem Cells." Cell Rep 19(6): 1101-1109. Oh, E., R. Jeremian, G. Oh, D. Groot, M. Susic, K. Lee, K. Foy, P. W. Laird, A. Petronis and V. Labrie (2017). "Transcriptional heterogeneity in the lactase gene within cell-type is linked to the epigenome." Sci Rep 7: 41843. Back To Top Panaro, B. L., G. B. Flock, J. E. Campbell, J. L. Beaudry, X. Cao and D. J. Drucker (2017). 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2014 Adissu, H. A., J. D. Baird and G. A. Wood (2014). "A Case of Bilateral Auricular Chondritis in a Heifer." Case Reports in Veterinary Medicine 2014: 1-4. (co-authored by TCP staff) Adissu, H. A., J. Estabel, D. Sunter, E. Tuck, Y. Hooks, D. M. Carragher, K. Clarke, N. A. Karp, P. Sanger Mouse Genetics, S. Newbigging, N. Jones, L. Morikawa, J. K. White and C. McKerlie (2014). "Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen." Dis Model Mech 7(5): 515-524. (co-authored by TCP staff) Amini-Nik, S., E. Cambridge, W. Yu, A. Guo, H. Whetstone, P. Nadesan, R. Poon, B. Hinz and B. A. Alman (2014). "beta-Catenin-regulated myeloid cell adhesion and migration determine wound healing." J Clin Invest 124(6): 2599-2610. Baht, G. S., D. Silkstone, P. Nadesan, H. Whetstone and B. A. Alman (2014). "Activation of hedgehog signaling during fracture repair enhances osteoblastic-dependent matrix formation." J Orthop Res 32(4): 581-586. Behringer, R., M. Gertsenstein, K. V. Nagy and A. Nagy (2014). Manipulating the Mouse Embryo: A Laboratory Manual, Cold Spring Harbor Laboratory Press. (co-authored by TCP staff) Bilodeau, M., S. Shojaie, C. Ackerley, M. Post and J. Rossant (2014). "Identification of a proximal progenitor population from murine fetal lungs with clonogenic and multilineage differentiation potential." Stem Cell Reports 3(4): 634-649. (co-authored by TCP staff) Brayton, C. F., C. McKerlie and S. Brown (2014). Analysis of Phenotype. Transgenic Animal Technology: A Laboratory Handbook: 431. (coauthored by TCP staff) Brown, S. (2014). "Animal models: Mouse already being charted gene by gene." Nature 508(7496): 319-319. (co-authored by TCP staff) Cahill, L. S., C. L. Laliberte, X. J. Liu, J. Bishop, B. J. Nieman, J. S. Mogil, R. E. Sorge, C. D. Jones, M. W. Salter and R. M. Henkelman (2014). "Quantifying blood-spinal cord barrier permeability after peripheral nerve injury in the living mouse." Mol Pain 10(1): 60. (co-authored by Mouse Imaging Centre staff) Back To Top Cardelli, M. and J. E. Aubin (2014). "ERRgamma is not required for skeletal development but is a RUNX2-dependent negative regulator of postnatal bone formation in male mice." PLoS One 9(10): e109592. Chen, F., R. Guo, S. Itoh, L. Moreno, E. Rosenthal, T. Zappitelli, R. A. Zirngibl, A. Flenniken, W. Cole, M. Grynpas, L. R. Osborne, W. Vogel, L. Adamson, J. Rossant and J. E. Aubin (2014). "First mouse model for combined osteogenesis imperfecta and Ehlers-Danlos syndrome." J Bone Miner Res 29(6): 1412-1423. (co-authored by TCP staff) Delgado-Olguin, P., L. T. Dang, D. He, S. Thomas, L. Chi, T. Sukonnik, N. Khyzha, M. W. Dobenecker, J. E. Fish and B. G. Bruneau (2014). "Ezh2-mediated repression of a transcriptional pathway upstream of Mmp9 maintains integrity of the developing vasculature." Development 141(23): 4610-4617. Dib, S., S. Xiao, D. Miletic and J. Robertson (2014). "Gene targeting of mouse Tardbp negatively affects Masp2 expression." PLoS One 9(4): e95373. Figueiredo, C. A., P. C. Drohomyrecky, S. D. McCarthy, D. Leontyev, X. Z. Ma, D. R. Branch and S. E. Dunn (2014). "Optimal attenuation of experimental autoimmune encephalomyelitis by intravenous immunoglobulin requires an intact interleukin-11 receptor." PLoS One 9(7): e101947. Gertsenstein, M. (2014). “Tetraploid Complementation Assay.” The Guide to Investigation of Mouse Pregnancy: 107 & 489. (co-authored by TCP staff) Hayes, M., X. Gao, L. X. Yu, N. Paria, R. M. Henkelman, C. A. Wise and B. Ciruna (2014). "ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease." Nat Commun 5: 4777. (co-authored by Mouse Imaging Centre staff) Back To Top Johnson, R. M., E. Papp, I. Grandal, P. E. Kowalski, L. Nutter, R. C. Wong, A. M. Joseph-George, J. S. Danska and C. J. Guidos (2014). "MuLVrelated endogenous retroviral elements and Flt3 participate in aberrant end-joining events that promote B-cell leukemogenesis." Genes Dev 28(11): 1179-1190. Johswich, A., C. Longuet, J. Pawling, A. Abdel Rahman, M. Ryczko, D. J. Drucker and J. W. Dennis (2014). "N-glycan remodeling on glucagon receptor is an effector of nutrient sensing by the hexosamine biosynthesis pathway." J Biol Chem 289(23): 15927-15941. Kabaroff, L., A. Gupta, S. Menezes, Y. Babichev, R. C. Kandel, C. J. Swallow, B. C. Dickson and R. A. Gladdy (2014). "Development of genetically flexible mouse models of sarcoma using RCAS-TVA mediated gene delivery." PLoS One 9(4): e94817. Kunath, T., Y. Yamanaka, J. Detmar, D. MacPhee, I. Caniggia, J. Rossant and A. Jurisicova (2014). "Developmental differences in the expression of FGF receptors between human and mouse embryos." Placenta 35(12): 1079-1088. Li, H., D. Qu, A. McDonald, S. M. Isaac, K. J. Whiteley, H. K. Sung, A. Nagy and S. L. Adamson (2014). "Trophoblast-specific reduction of VEGFA alters placental gene expression and maternal cardiovascular function in mice." Biol Reprod 91(4): 87. Liu, J., U. Deutsch, I. Fung and C. G. Lobe (2014). "Conditional and inducible transgene expression in endothelial and hematopoietic cells using Cre/ and tetracycline-off systems." Exp Ther Med 8(5): 1351-1356. Michael, I. P., P. D. Westenskow, S. Hacibekiroglu, A. C. Greenwald, B. G. Ballios, T. Kurihara, Z. Li, C. M. Warren, P. Zhang, E. Aguilar, L. Donaldson, V. Marchetti, T. Baba, S. M. Hussein, H. K. Sung, M. L. Iruela-Arispe, J. M. Rini, D. van der Kooy, M. Friedlander and A. Nagy (2014). "Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye." EMBO Mol Med 6(5): 604623. Mishra, A. and T. Bubela (2014). "Legal agreements and the governance of research commons: lessons from materials sharing in mouse genomics." OMICS 18(4): 254-273. Back To Top Perova, T., I. Grandal, L. M. Nutter, E. Papp, I. R. Matei, J. Beyene, P. E. Kowalski, J. K. Hitzler, M. D. Minden, C. J. Guidos and J. S. Danska (2014). "Therapeutic potential of spleen tyrosine kinase inhibition for treating high-risk precursor B cell acute lymphoblastic leukemia." Sci Transl Med 6(236): 236ra262. Peter, M. R., M. Jerkic, V. Sotov, D. N. Douda, D. S. Ardelean, N. Ghamami, F. Lakschevitz, M. A. Khan, S. J. Robertson, M. Glogauer, D. J. Philpott, N. Palaniyar and M. Letarte (2014). "Impaired resolution of inflammation in the Endoglin heterozygous mouse model of chronic colitis." Mediators Inflamm 2014: 767185. Pop, M., V. Ramanan, F. Yang, L. Zhang, S. Newbigging, N. R. Ghugre and G. A. Wright (2014). "High-resolution 3-D T1*-mapping and quantitative image analysis of GRAY ZONE in chronic fibrosis." IEEE Trans Biomed Eng 61(12): 2930-2938. (co-authored by TCP staff) Pop, M., M. Sermesant, S. Oduneye, S. Ghate, L. Biswas, R. Flor, S. Newbigging, E. Crystal, N. Ayache and G. A. Wright (2014). Progress on Customization of Predictive MRI-Based Macroscopic Models from Experimental Data. Statistical Atlases and Computational Models of the Heart. Imaging and Modelling Challenges, Springer: 152-161. (co-authored by TCP staff) Portmann, T., M. Yang, R. Mao, G. Panagiotakos, J. Ellegood, G. Dolen, P. L. Bader, B. A. Grueter, C. Goold, E. Fisher, K. Clifford, P. Rengarajan, D. Kalikhman, D. Loureiro, N. L. Saw, Z. Zhengqui, M. A. Miller, J. P. Lerch, R. M. Henkelman, M. Shamloo, R. C. Malenka, J. N. Crawley and R. E. Dolmetsch (2014). "Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome." Cell Rep 7(4): 1077-1092. (co-authored by Mouse Imaging Centre staff) Rennie, M.Y., J. Mu, A. Rahman, D. Qu, K.J. Whiteley, J.G. Sled, and S.L. Adamson. (2014). “The Uteroplacental, Regoplacental, and Yolk Sac Circulations in the Mouse.” The Guide to Investigation of Mouse Pregnancy: 201. 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"Nanoparticle exposure in animals can be visualized in the skin and analysed via skin biopsy." Nat Commun 5: 3796. Thomson, B. R., S. Heinen, M. Jeansson, A. K. Ghosh, A. Fatima, H. K. Sung, T. Onay, H. Chen, S. Yamaguchi, A. N. Economides, A. Flenniken, N. W. Gale, Y. K. Hong, A. Fawzi, X. Liu, T. Kume and S. E. Quaggin (2014). "A lymphatic defect causes ocular hypertension and glaucoma in mice." J Clin Invest 124(10): 4320-4324. (co-authored by TCP staff) Tsui, A. K., P. A. Marsden, C. D. Mazer, J. G. Sled, K. M. Lee, R. M. Henkelman, L. S. Cahill, Y. Q. Zhou, N. Chan, E. Liu and G. M. Hare (2014). "Differential HIF and NOS responses to acute anemia: defining organ-specific hemoglobin thresholds for tissue hypoxia." Am J Physiol Regul Integr Comp Physiol 307(1): R13-25. . (co-authored by Mouse Imaging Centre staff) Ussher, J. R., L. L. Baggio, J. E. Campbell, E. E. Mulvihill, M. Kim, M. G. Kabir, X. Cao, B. M. Baranek, D. A. Stoffers, R. J. Seeley and D. J. Drucker (2014). "Inactivation of the cardiomyocyte glucagon-like peptide-1 receptor (GLP-1R) unmasks cardiomyocyte-independent GLP-1Rmediated cardioprotection." Mol Metab 3(5): 507-517. Van Doormaal, M., Y. Q. Zhou, X. Zhang, D. A. Steinman and R. Mark Henkelman (2014). "Inputs for subject-specific computational fluid dynamics simulation of blood flow in the mouse aorta." J Biomech Eng 136(10): 101008. . (co-authored by Mouse Imaging Centre staff) Wong, M. D., Y. Maezawa, J. P. Lerch and R. M. Henkelman (2014). "Automated pipeline for anatomical phenotyping of mouse embryos using micro-CT." Development 141(12): 2533-2541. (co-authored by Mouse Imaging Centre staff) Wu, A. M., M. Yang, P. Dalvi, A. L. Turinsky, W. Wang, D. Butcher, S. E. Egan, R. Weksberg, P. A. Harper and S. Ito (2014). "Role of STAT5 and epigenetics in lactation-associated upregulation of multidrug transporter ABCG2 in the mammary gland." Am J Physiol Endocrinol Metab 307(7): E596-610. Zander, M. A., G. I. Cancino, T. Gridley, D. R. Kaplan and F. D. Miller (2014). "The Snail transcription factor regulates the numbers of neural precursor cells and newborn neurons throughout mammalian life." PLoS One 9(8): e104767. Back To Top Cost Estimate

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