Teacher Resources - GeneEd - Genetics, Education, Discovery [PDF]

A key question that is woven through this lesson is how we as a society can use genetics to keep people safe, solve crim

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Lesson plans, genetic educational materials, printable activity sheets, and other teaching resources for educators seeking to increase genetic and genomic literacy.

DNA Forensics DNA, Genes, Chromosomes Epigenetics/Inheritance and the Environment

MATERIALS FOR TEACHER RESOURCES

Evolution

BIOSTATISTICS

Genetic Conditions

Basic Probability and Chi-Squared Tests (Lesson Plans/Lesson Activities) Description: An expert authored advanced in-class exercise teaching critical skills for classic genetic analysis, including probability,

Heredity/Inheritance Patterns

making predictions, and assessment. Source: Genetics Society of America | URL: http://www.genetics-gsa.org/education/GSAPREP.2013.005.shtml

Top Issues In Genetics

Human Genetic Variation: A Flipped Classroom Exercise in Cultural Competency (Lesson Plans/Lesson Activities) Description: An expert authored advanced in-class case discussion teaching concepts of population genetics and genetic variation. Source: Genetics Society of America | URL: http://www.genetics-gsa.org/education/GSAPREP.2013.003.shtml

Iceland’s Genetic Database: Good or Bad Idea? (PDF 28.17 KB, Lesson Plans/Lesson Activities) Description: This lesson examines issues stemming from genetic databanks and population genetics studies. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/genomics/lessons/hlodanlessons.pdf

K-12 Statistics Education Webinars Description: Recorded web-based seminars on K-12 statistics education topics. The webinars aim to support teachers in their efforts to master statistics and incorporate core concepts into their classrooms. Source: American Statistical Association | URL: https://www.amstat.org/asa/education/K-12-Statistics-Education-Webinars.aspx

Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics (Lesson Plans/Lesson Activities) Description: A lesson that requires students to work through a series of questions pertaining to the genetics of sickle cell disease and its relationship to malaria. These questions will probe students' understanding of Mendelian genetics, probability, pedigree analysis, and chi-square statistics. Source: Howard Hughes Medical Institute | URL: https://www.hhmi.org/biointeractive/mendelian-genetics-probability-pedigree-and-chi-square-statistics

Population Genetics (Lesson Plans/Lesson Activities) Description: In this lesson, students simulate what happens to a population containing sickle cell trait carriers over several generations in the presence of a high, medium, or low incidence of malaria. Students analyze class data to understand trends in each population and the selective forces at play. Students also review and discuss real-world data. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=5&l=3&c=0

Population Genetics of Plant Pathogens Description: Population biology focuses on the biological processes that affect populations of organisms. Population biology is relevant to plant pathology because plant diseases are caused by populations of parasites. Explore concepts of gene mutation, genetic drift, gene flow and more through this series. Source: The American Phytopathological Society | URL: http://www.apsnet.org/edcenter/advanced/topics/PopGenetics/Pages/default.aspx

Retinoblastoma, Cystic Fibrosis, and Body Mass Index, Oh My! (PDF 196.72 KB, Lesson Plans/Lesson Activities) Description: Building on their intuitive understanding of twin study correlations, students analyze subsets of data to determine how strong the environmental and genetic influences are for three different traits/conditions. Students use mean, standard deviation, and Pearson correlation coefficient to describe and make meaning of their data. They also graph their data and correlations, and compare the results from their subset of data to the results of a group using a different subset of the data. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/NatureNurture_L2_corrected.pdf

Scitable Faculty Resources Description: The Scitable faculty resource pages include a tool for creating virtual classrooms, the Scitable Faculty Discussion Group, and a variety of instructive courses for educators. Source: Nature Education | URL: http://www.nature.com/scitable/faculty-page

Statistics Education Web (STEW) Description: STEW is a resource for peer-reviewed lesson plans for K-12 teachers. The statistical concepts follow the recommendations of the Guidelines for Assessment and Instruction in Statistics Education (GAISE) Report: A Pre-K-12 Curriculum Framework, Common Core State Standards for Mathematics, and NCTM Principles and Standards for School Mathematics. Source: American Statistical Association | URL: http://www.amstat.org/education/stew/index.cfm

The Probabilities of Problems: A Look at Inheritance (Lesson Plans/Lesson Activities) Description: Students learn how to calculate the the probabilities of passing on certain genetic disorders and then evaluate case studies involving genetic testing. Source: PBS & WGBH Educational Foundation | URL: http://www.pbs.org/inthebalance/archives/ourgenes/lesson_probabilities.html

BIOTECHNOLOGY Biotechnology: An Agricultural Dilemma (PDF 28.17 KB, Lesson Plans/Lesson Activities) Description: Students develop an understanding of agricultural needs in developing nations, research the types of genetically modified crop plants, examine the impacts of genetically modified plants on the environment, analyze the benefits and risks of genetically modified crop plants, support and debate a view based on biological knowledge, and apply scientific information to resolve a societal issue. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/biotechnology/lessons/altierilessons.pdf

Can you taste PTC? (PDF 1,989.26 KB, Lesson Plans/Lesson Activities) Description: In this lesson, students use a Single Nucleotide Polymorphism (SNP) kit to determine their genotype for the TAS2R38 gene. While waiting for their results, students also test their PTC tasting ability (phenotype). The class then analyzes both phenotype and genotype data to determine which allele is the taster allele and which allele is the non-taster allele. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/GeneticsOfTaste_L3_corrected.pdf

Catch Up on Tomato Technology (505.5 KB, Lesson Plans/Lesson Activities) Description: This lesson is a tool to demonstrate how various technological advances have changed the tomato and the tomato industry over the years. The technology includes both selective breeding and genetic engineering. Source: California Foundation for Agriculture in the Classroom | URL: http://archives.lessoncorner.com/e9f8ef1e4c901b193.pdf

Cloning Animals and Plants: Any Difference? (PDF 21.04 KB, Lesson Plans/Lesson Activities) Description: In this lesson plan students storyboard the history of famous animal clones, examine the differences between animal and plant cloning, experiment cloning a Coleus plant, and design a controlled plant experiment. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/biotechnology/lessons/pecorino.pdf

Debating the Ethical and Legal Implications of Genetic Testing (PDF 904.59 KB, Lesson Plans/Lesson Activities) Description: Students explore the difference between ethical and legal issues and use an analytical framework to work through an ethical scenario before researching and debating two genetic testing scenarios. Additional chapters from DNA: Promise and Peril (McCabe, Linda L. and McCabe, Edward R.B. Regents of the University of California Press, 2008.) provide a starting point for their research. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/ELSI_L3.pdf

Direct-to-Consumer Genetic Testing (Lesson Plans/Lesson Activities) Description: This lesson provides students the opportunity to explore the excitement and challenges related to the direct-toconsumer (DTC) genetic testing industry. How do consumers react to genetic information gleaned from DTC services? What information can be learned through a DTC test, and do consumers need or want a doctor or genetic counselor to access this information? Source: Personal Genetics Education Project | URL: http://www.pged.org/lesson-plans/#DTC

Extracting DNA (Lesson Plans/Lesson Activities) Description: In this lesson, students develop understanding of DNA by modeling the process of DNA extraction. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/extracting-dna/

Genetic Testing: Road Map or Crystal Ball? (Lesson Plans/Lesson Activities) Description: Students are exposed to the pros and cons of genetic testing and must take a stand by writing a position paper, after viewing the "Who Gets to Know?" video and/or reading case studies from the Our Genes/Our Choices series. Source: PBS & WGBH Educational Foundation | URL: http://www.pbs.org/inthebalance/archives/ourgenes/lesson_genetictesting.html

Genetics and Reproduction (Lesson Plans/Lesson Activities) Description: This lesson addresses the genetic reproductive technologies that are being used by individuals who, for a variety of reasons, wish to know and/or have some choice about the genetic makeup of their children. It begins with a discussion of the technologies that can reveal the genetic makeup of fetuses and then moves on to a technology called preimplantation genetic diagnosis (PGD). The goal of this lesson is to give students an opportunity to discuss many aspects of PGD such that they become aware of the diversity of opinions surrounding PGD. Source: Personal Genetics Education Project | URL: http://www.pged.org/lesson-plans/#reproduction

How does genotyping work? (Lesson Plans/Lesson Activities) Description: Students learn about DNA extraction, PCR, restriction digest, and gel electrophoresis through a combination of virtual labs and class discussion. Students learn about the TAS2R38 gene which is involved in the ability to taste bitter foods. Students perform simple bioinformatics using primer sequences and allele sequences of TAS2R38. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=4&l=2&c=0

Introduction to Genetically Modified Organisms (Lesson Plans/Lesson Activities) Description: Students take a pre-test to help the instructor guage pre-existing knowledge and attitudes about genetic modification. After a presentation on the basics of recombinant DNA technology, students read an article about genetically modified foods that presents both the benefits and concerns this use of recombinant DNA technology has brought up. Students then work in small groups reading articles that go more in depth about either a pro or con of GMOs. After each group briefly presents the arguments for or against GMOs from their article, students are asked to write an opinion paper for homework. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=8&l=1&c=0

Is it Genetically Modified? (PDF 198.25 KB, Lesson Plans/Lesson Activities) Description: Students are introduced to and asked to think about the procedures used to detect GMO foods, namely PCR and gel electrophoresis. In small groups, student then get to test foods brought from home for the presence of GMO ingredients using the Bio-Rad GMO Investigator Kit. At every step of the way, students are asked to think about why each step is important. Finally, students must analyze and interpret their experimental results, write a comprehensive lab report, present their findings to their classmates. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/VeggieAndFruitTales_L2.pdf

Maintaining Plant Genebanks (PDF 44.43 KB, Lesson Plans/Lesson Activities) Description: A lesson plan exploring the benefits and problems of maintaining plant genebanks globally. Students research the science behind and the need for plant genebanks, consider the rationale for gaining ownership over scientific information, formulate an opinion about the costs and uses of high tech scientific applications, and understand the implications of reliance on biotechnology. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/biodiversity/lessons/hawtin_cherfaslessons.pdf

Personalized Medicine (Lesson Plans/Lesson Activities) Description: Personalized medicine, also referred to as precision medicine, holds great promise to improve healthcare. As the cost of genetic analysis decreases and research advances, it is becoming increasingly possible to include the genetic make-up of a person in the repertoire of tools that inform his or her healthcare. This lesson asks students to delve into the hopes and challenges of personalized medicine and to consider the practical applications of genetic analysis in medicine. Source: Personal Genetics Education Project | URL: http://www.pged.org/lesson-plans/#PM

Personalized Medicine (aka Pharmacogenomics) (Lesson Plans/Lesson Activities) Description: In this teaching module students will learn about the concept of personalized medicine; how differences in our genes affect whether a drug treatment will be successful or have serious side effects, and how we can use this information to customize treatments for individual patients. Students will participate in a hands-on activity to further demonstrate how subtle genetic differences affect a patients response to medication. Source: UNC School of Medicine | URL: http://ncdnaday.org/learn-more/resources-2/

Protecting Athletes with Genetic Conditions: Sickle Cell Trait (Lesson Plans/Lesson Activities) Description: As the genetic basis for many health conditions is revealed, some doctors, coaches, and academic and athletic organizations are wondering whether genetic analysis can provide health and safety benefits for athletes. As of 2013, the National Collegiate Athletic Association (NCAA), the governing body of college sports in the United States, began screening all of its athletes for the genetic condition sickle cell trait (SCT). This lesson explores the discussion surrounding this policy and asks students to examine how genetics might impact their own athletic choices and options. Source: Personal Genetics Education Project | URL: http://www.pged.org/lesson-plans/#SCT

Risks and Benefits (Lesson Plans/Lesson Activities) Description: This lesson provides students with an opportunity to further their understanding of the risks and benefits associated with innovations in science and technology. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/risks-and-benefits/

Spot the Difference - Zebrafish (Lesson Plans/Lesson Activities) Description: Step into the shoes of a genetic scientist and carry out a phenotype analysis with the model organism, zebrafish. Source: Genome Research Limited and Wellcome Trust Sanger Institute | URL: http://www.yourgenome.org/activities/spot-the-difference-zebrafish

Teacher Guide - Cloning (Lesson Plans/Lesson Activities) Description: Four captivating lesson guides on cloning methods, legislation, and history/timeline. Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/cloning/

Technological Advances in Health (Lesson Plans/Lesson Activities) Description: Students will learn how technology influences human existence by examining the benefits and risks of different biotechnological advances. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/technological-advances-in-health/

What Can I Learn From Worms? Regeneration, Stem Cells, and Models (Lesson Plans/Lesson Activities) Description: A series of high quality lesson plans exploring a variety of topics including the cell cycle and the use of model species in biomedical research. You may need to register to view the lesson plans, but the plans and registration is free. Source: Project NEURON, University of Illinois | URL: https://neuron.illinois.edu/units/what-can-i-learn-from-worms

What Changes Our Minds? Toxicants, Exposure, and the Environment (Lesson Plans/Lesson Activities) Description: A series of lesson plans and laboratory experiments exploring the effects of environmental exposure to chemicals. You may need to register to view the plans, but the lesson plans and registration is free. Source: Project NEURON, University of Illinois | URL: https://neuron.illinois.edu/units/what-changes-our-minds-toxicants

Who Owns Rights To Pharmacogenetic Information? (PDF 28.17 KB, Lesson Plans/Lesson Activities) Description: This lesson examines potential benefits, risks, and ethical concerns of designer drugs. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/genomics/lessons/barashlessons.pdf

CELL BIOLOGY Cell Differentiation and Gene Expression (Lesson Plans/Lesson Activities) Description: This lesson uses the example of cell differentiation to introduce the concept of differential gene expression. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=7&l=1&c=0

Cells 2: The Cell as a System (Lesson Plans/Lesson Activities) Description: In this lesson, students review cell structures and investigate how the components of a cell operate as a system. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/cells-2-the-cell-as-a-system/

cK-12 Foundation - Teachers Description: Ck-12 Foundation offers life-science simulations to immerse students in an interactive learning experience, practice problems, free full-text FlexBook Textbooks, tools for leading group discussions and more. Source: cK-12 Foundation | URL: http://www.ck12.org/life-science/

Genes in Motion - Mitosis Lesson Guide (PDF 331.37 KB, Lesson Plans/Lesson Activities) Description: This collaborative program was developed by a diverse group of experts including the Liz Lerman Dance Exchange to teach genetics through movement, spoken word, and creative applications of technology. Topics covered in this program include mitosis, bioinformatics, induced mutation, and natural mutation. These topics support materials currently taught in a high school biology classrooms. Source: National Human Genome Research Institute | URL: http://www.genome.gov/Pages/Education/DNADay/NewsAndFeatures/GenesinMotionLessonGuide.pdf

Mitosis (Lesson Plans/Lesson Activities) Description: In this lesson students learn about mitosis using the Mitosis app. They make physical representations of mitosis on a poster board, and write and preform a skit to show the process of mitosis. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/mitosis/

Mitosis - The Dance of the Chromosomes (PDF 304.58 KB, Lesson Plans/Lesson Activities) Description: A PowerPoint presentation on mitosis Source: National Human Genome Research Institute | URL: http://www.genome.gov/Pages/Education/DNADay/NewsAndFeatures/MitosisCHD4-30-07.pdf

Teacher Guide - Amazing Cells (Lesson Plans/Lesson Activities) Description: From the structure and function of organelles to communication on a molecular level, these 8 lesson plans explore the inner-most workings of cells in a dynamic and realistic way. Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/cells/

The Invisible Kingdom (Lesson Plans/Lesson Activities) Description: This lesson helps students develop an understanding of the characteristics and diversity of microbial life. Readings prompt discussions a variety of topics ranging from antibiotic resistance to horizontal gene transfer. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/the-invisible-kingdom/

Using Technology to Study Cellular and Molecular Biology (Lesson Plans/Lesson Activities) Description: A curriculum supplement for high school students exploring how technology advancements in cell biology have been used to enhanced health Source: National Center for Research Resources and Office of Science Education | URL: https://science.education.nih.gov/HighSchool/CellularAndMolecularBiology

What Can I Learn From Worms? Regeneration, Stem Cells, and Models (Lesson Plans/Lesson Activities) Description: A series of high quality lesson plans exploring a variety of topics including the cell cycle and the use of model species in biomedical research. You may need to register to view the lesson plans, but the plans and registration is free. Source: Project NEURON, University of Illinois | URL: https://neuron.illinois.edu/units/what-can-i-learn-from-worms

DNA FORENSICS DNA - A Molecular Identity (Lesson Plans/Lesson Activities) Description: This lesson plan engages students in learning what DNA is and about different DNA profiling techniques. Students examine three real cases where DNA evidence was an essential component and evaluate the benefits and possible misuses of DNA information. Source: US National Library of Medicine | URL: https://www.nlm.nih.gov/visibleproofs/education/dna/index.html

DNA, Crime and Law Enforcement (Lesson Plans/Lesson Activities) Description: The collection and analysis of DNA is an important tool in law enforcement. This lesson explores the challenge of establishing ethical and legal frameworks in a timely manner to guide the use of newly developed technologies. A key question that is woven through this lesson is how we as a society can use genetics to keep people safe, solve crimes and, at the same time, develop policies that provide appropriate safeguards and privacy protections. Source: Personal Genetics Education Project | URL: http://pged.org/genetics-and-crime/

Entomology in Action (Lesson Plans/Lesson Activities) Description: Lesson plans and teaching aids on entomology Source: US National Library of Medicine | URL: http://www.nlm.nih.gov/visibleproofs/education/entomology/index.html

Entomology Resources for Educators Description: Lesson plans, student contests, educator awards, and teacher workshops to help educators increase science literacy. Source: Entomological Foundation | URL: http://www.entfdn.org/

Forensics (Lesson Plans/Lesson Activities) Description: This module teaches shows students how DNA is analyzed by forensic scientists in order to link a DNA sample to a particular individual. To do this, forensic scientists use powerful molecular biology techniques such as PCR, restriction digests and gel electrophoresis. To learn more about DNA and how it is used by forensic scientists, students will isolate their own DNA from saliva. Using their new-found understanding of DNA and forensics techniques, students will help solve the case of the missing mascot. Source: UNC School of Medicine | URL: http://ncdnaday.org/learn-more/resources-2/

Short Tandem Repeats...and Murder! (Lesson Plans/Lesson Activities) Description: The lesson plan guides students through PCR and gel electrophoresis simulations for six short tandem repeat (STR) loci. They use their data to solve a murder. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=10&l=1&c=0

Short Tandem Repeats...and Murder! (Short Version) (Lesson Plans/Lesson Activities) Description: This lesson plan involves solving a murder case through analysis of short tandem repeat (STR) loci of forensic DNA samples. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=10&l=2&c=0

Take the Case: Chain of Evidence (Lesson Plans/Lesson Activities) Description: Students will use the interactive Take the Case - Chain of Evidence to investigate a crime scene and analyze evidence, interview suspects, and solve the case. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/take-case-chain-evidence/

Using QR Codes in Forensic Science (Lesson Plans/Lesson Activities) Description: In this lesson, students use mobile technology and knowledge of forensic science to research a crime case. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/forensic-science/

DNA, GENES, CHROMOSOMES Analyzing Chromosomes (PDF 7,056.8 KB, Lesson Plans/Lesson Activities) Description: Students learn about chromosome analysis by completing a partial karyotype and assess the karyotype for anomalies. Students practice sharing bad news to parents. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/AdventuresInKaryotyping_L2.pdf

Breakfast Proteins Description: Model the central dogma of molecular biology by constructing a colorful chain using a simple code (and some delicious cereal). Source: Exploratorium | URL: https://www.exploratorium.edu/snacks/breakfast-proteins

Cell Differentiation and Gene Expression (Lesson Plans/Lesson Activities) Description: This lesson uses the example of cell differentiation to introduce the concept of differential gene expression. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=7&l=1&c=0

cK-12 Foundation - Teachers Description: Ck-12 Foundation offers life-science simulations to immerse students in an interactive learning experience, practice problems, free full-text FlexBook Textbooks, tools for leading group discussions and more. Source: cK-12 Foundation | URL: http://www.ck12.org/life-science/

Cracking the Genetic Code (Lesson Plans/Lesson Activities) Description: This lesson explores what the knowledge of DNA can tell us about ourselves and other organisms and species. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/cracking-the-genetic-code/

Decoding the Flu (Lesson Plans/Lesson Activities) Description: This classroom activity teaches how to read and interpret information stored in DNA. It makes use of personal response systems (clickers) and a PowerPoint presentation. The story centers on a CDC student intern, Jason. While working with a CDC team in Mexico, Jason is the only person who does not get sick from a new strain of flu. It is up to Jason to use molecular data collected from different local strains of flu to identify which one may be causing the illness. Source: National Center for Case Study Teaching in Science, University at Buffalo | URL: http://sciencecases.lib.buffalo.edu/cs/collection/detail.asp?case_id=597&id=597

DNA Repair - Exploring the 2015 Nobel Prize Winning work of two NC scientists (Lesson Plans/Lesson Activities) Description: This University of North Carolina teaching module explores several built-in protection mechanisms our bodies use to prevent and repair damage to DNA. In 2015, Dr. Aziz Sancar from UNC Chapel Hill and Dr. Paul Modrich from Duke University were awarded the Nobel Prize in Chemistry for their work on understanding DNA repair. Students will extract their own DNA from saliva and analyze REAL data from Dr. Sancars Nobel-winning research. Source: UNC School of Medicine | URL: http://ncdnaday.org/learn-more/resources-2/

DNA Replication: A case discussion of a landmark paper by Meselson and Stahl (Lesson Plans/Lesson Activities) Description: An expert authored advanced in-class exercise involving literature assessment and detailed exploration of DNA replication Source: Genetics Society of America | URL: http://www.genetics-gsa.org/education/GSAPREP.2013.006.shtml

Do you have good taste? (PDF 173.5 KB, Lesson Plans/Lesson Activities) Description: Students explore their sense of taste by recording the taste sensations detected when standardized solutions are applied to different areas of their tongue. Students learn that their genotype for certain genes influences their tasting phenotype through the processes of transcription and translation of the genes to produce taste receptor proteins. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/GeneticsOfTaste_L1.pdf

Environmental Factors, Inducible Promoters, and Gene Expression (Lesson Plans/Lesson Activities) Description: Students explore how changes in gene expression are induced by environmental conditions. The lesson plan involves a bacterial transformation experiment, discussion on skin tanning, and a presentation assignment on regulated gene expression. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=7&l=2&c=0

Extracting DNA (Lesson Plans/Lesson Activities) Description: In this lesson, students develop understanding of DNA by modeling the process of DNA extraction. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/extracting-dna/

Genetic Timeline (Lesson Plans/Lesson Activities) Description: A lesson plan highlighting key discoveries that have led to our present understanding of the human genome Source: National Human Genome Research Institute | URL: http://www.genome.gov/10506099

Genomics and Human Identity (Lesson Plans/Lesson Activities) Description: Bring genomics to life for your high school students with this lesson plan. The lessons encourage hands-on, inquirybased learning and include genomic concepts and research projects. Source: National Human Genome Research Institute and the Smithsonian National Museum of Natural History | URL: https://unlockinglifescode.org/connections/newsletter/genomics-and-human-identity

Inside/Outside the Human Genome Project (Lesson Plans/Lesson Activities) Description: In this cooperative learning activity for grades 6-8, students combine a jigsaw learning technique with an inside/outside review game to learn about DNA, genes, chromosomes and the Human Genome Project. Source: PBS & WGBH Educational Foundation | URL: http://www.pbs.org/inthebalance/archives/ourgenes/lesson_insideoutside.html

Measuring Gene Expression (PDF 1,317.88 KB, Lesson Plans/Lesson Activities) Description: Students come up with an experimental design to test 1) that different cell types from the same person result from differences in gene expression OR 2) that tanning is result of skin cells changing their gene expression. Students complete a virtual lab that introduces them to microarray technology. Macromodel Microarrays are used in small groups to measure the gene expression for cancerous versus normal breast tissue, and each group must make a treatment recommendation based on the gene expression results. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/GeneExpression_L3_corrected.pdf

Molecular Genetics (Lesson Plans/Lesson Activities) Description: Lesson guides and video slide show presentation on HIV viral replication and other molecular genetic topics Source: Baylor College of Medicine Center for Educational Outreach | URL: http://www.bioedonline.org/lessons-and-more/lessons-by-topic/molecular-genetics/

Origami DNA (Lesson Plans/Lesson Activities) Description: This activity brings to life the double helix structure of DNA by enabling your students to make their own paper model. Instructions and model templates are available for download. Source: Wellcome Trust Sanger Institute | URL: http://www.yourgenome.org/activities/origami-dna

PBS LearningMedia Description: A Web site providing teachers with strategies, tools, and professional development resources for incorporating digital learning in the classroom Source: WGBH Educational Foundation | URL: http://www.pbslearningmedia.org/

Power My Learning Description: A web-based platform with online learning activities for K-12 students, parents, and educators. You will need to register to use the site, but registration is free. Source: Power My Learning | URL: http://powermylearning.org/

Reading DNA (PDF 313.02 KB, Lesson Plans/Lesson Activities) Description: Students use edible models of the DNA molecule to transcribe an mRNA sequence, then translate it into a protein. Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/dna/ReadingDNA.pdf

Scitable Faculty Resources Description: The Scitable faculty resource pages include a tool for creating virtual classrooms, the Scitable Faculty Discussion Group, and a variety of instructive courses for educators. Source: Nature Education | URL: http://www.nature.com/scitable/faculty-page

Secrete Codon Description: With beads on a string, use the one-letter abbreviations for amino acids to make a secret message. Source: Exploratorium | URL: https://www.exploratorium.edu/snacks/secret-codon

Sequence Bracelets Description: In this activity you can make a bracelet of DNA sequence from organisms including a human, chimpanzee, butterfly, carnivorous plant or flesh-eating bacteria. Source: Genome Research Limited and Wellcome Trust Sanger Institute | URL: http://www.yourgenome.org/activities/sequence-bracelets

Teacher Guide - Have Your DNA and Eat It Too (PDF 266.17 KB, Lesson Plans/Lesson Activities) Description: Lesson plan on the structure of DNA and a class activity building an edible double helix Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/dna/HaveYourDNAandEatItToo.pdf

Ten Captivating Tools for the DNA Classroom Description: Whether you are searching for something for DNA Day, looking for a little spice in your genetics unit, or offering resources to parents, students or colleagues - these ten perennial favorites are sure to please. Bookmark this for year-round use. Source: National Human Genome Research Institute and the Smithsonian National Museum of Natural History | URL: https://unlockinglifescode.org/captivating-tools-for-the-dna-classroom

Visualizing Gene-Expression Patterns Description: A slide show with video clips illustrating how scientists detect when a gene is being expressed in tissues Source: Howard Hughes Medical Institute | URL: http://media.hhmi.org/biointeractive/click/Visualizing_Gene_Expression/01.html

X or Y: Does it Make a Difference? (Lesson Plans/Lesson Activities) Description: Students learn and describe the functional differences between X and Y chromosomes, and explain the significance of these differences in the human genome. Source: Baylor College of Medicine Center for Educational Outreach | URL: http://www.bioedonline.org/lessons-and-more/lessons-by-topic/molecular-genetics/x-or-y-does-it-make-a-

difference/

Yummy Gummy DNA Description: Make your own edible DNA double helix out of sweets. Source: Genome Research Limited and Wellcome Trust Sanger Institute | URL: http://www.yourgenome.org/activities/yummy-gummy-dna

EPIGENETICS/INHERITANCE AND THE ENVIRONMENT Epigenetics Module (Lesson Plans/Lesson Activities) Description: These three lesson plans explore some of the mechanisms that turn genes on and off and how our environment can affect this. Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/epigenetics/

Genes, Environment and Genetic Complexity: Aggression in Humans (Lesson Plans/Lesson Activities) Description: Questions about whether genetics can, in part, explain violent, aggressive behavior in humans are not new. Recent episodes of large-scale violence, whether in schools or other public places, have renewed discussion about the intersection of crime, mental health and genetics. In this lesson, students are asked to examine popular but incorrect ideas related to the idea that a single gene or even set of genes can cause humans to behave aggressively. Source: Personal Genetics Education Project | URL: http://pged.org/lesson-plans/#aggression

NOVA scienceNOW - Epigenetics (Lesson Plans/Lesson Activities) Description: Students make a model of chromatin and use it to show how chemical tags that bond to the chromatin can influence its uncoiling. Source: WGBH Educational Foundation | URL: http://www.pbs.org/wgbh/nova/education/activities/3411_02_nsn.html

The Mystery of Calico Cats (Lesson Plans/Lesson Activities) Description: In this lesson, students explore the genetics and epigenetics behind calico cats. Using sex-linked Punnett squares, students must determine what the genotype for coat color is for calico cats. The class then discusses why dosage compensation for the X chromosome is necessary in females and how that relates to the patchy appearance and female sex of calico cats. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=1&l=3&c=0

What Changes Our Minds? Toxicants, Exposure, and the Environment Description: A series of lesson plans and laboratory experiments exploring the effects of environmental exposure to chemicals. You may need to register to view the plans, but the lesson plans and registration is free. Source: Project NEURON, University of Illinois | URL: https://neuron.illinois.edu/units/what-changes-our-minds-toxicants

What Makes Honey Bees Work Together? (Lesson Plans/Lesson Activities) Description: A series of lesson plans exploring how genes and environment affect behavior, as well as introduces students to research tools used to investigate gene expression. You may need to register to view the lesson plans, but the plans and registration is free. Source: Project NEURON, University of Illinois | URL: https://neuron.illinois.edu/units/what-makes-honey-bees-work-together

What Makes Me Tick...Tock? Circadian Rhythms, Genetics, and Health (Lesson Plans/Lesson Activities) Description: A series of lesson plans exploring how environment, genes, and proteins affect behavior. The lesson plans incorporate real-life examples, case studies, and interactive online components to teach concepts of epigenetics. You may need to register to view the lesson plans, but the plans and registration is free. Source: Project NEURON, University of Illinois | URL: https://neuron.illinois.edu/units/what-makes-me-tick-tock

EVOLUTION Applied Evolution: How Will We Get There from Here? (PDF 28.17 KB, Lesson Plans/Lesson Activities) Description: Students perform a simulated natural selection activity with candy, prepare a mock HIV court case, imagine Earth in the future, track a Hantavirus outbreak, conduct “Marty the Mutating Marcescens” experiment, and brainstorm a potential detergent enzyme. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/genomics/lessons/bulllessons.pdf

Beanbag Population Genetics (PDF 46.88 KB, Lesson Plans/Lesson Activities) Description: Classroom exercises demonstrating genetic drift and natural selection Source: Smithsonian National Museum of Natural History | URL: http://anthropology.si.edu/outreach/Teaching_Activities/pdf/BEANBAG.96.pdf

Bird Beaks (Lesson Plans/Lesson Activities) Description: In this lesson, students will explore the relationship between a birds beak and its ability to find food and survive in a given environment. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/bird-beaks/

cK-12 Foundation - Teachers Description: Ck-12 Foundation offers life-science simulations to immerse students in an interactive learning experience, practice problems, free full-text FlexBook Textbooks, tools for leading group discussions and more. Source: cK-12 Foundation | URL: http://www.ck12.org/life-science/

Classroom Activities - Natural Selection and Adaptation (Lesson Plans/Lesson Activities) Description: A teachers guide, educational video, student quiz, and activity plans for teaching natural selection and adaptation Source: Howard Hughes Medical Institute | URL: http://www.hhmi.org/biointeractive/making-fittest-natural-selection-and-adaptation

Classroom Activities: Battling Beetles (Lesson Plans/Lesson Activities) Description: A series of activities teaching concepts of natural selection, genetic variation, and evolution Source: Howard Hughes Medical Institute | URL: http://www.hhmi.org/biointeractive/classroom-activities-battling-beetles

Classroom Activities: Gene Switches (Lesson Plans/Lesson Activities) Description: Teaching materials on evolution and genetic variation with a classroom activity to model a gene switch Source: Howard Hughes Medical Institute | URL: http://www.hhmi.org/biointeractive/classroom-activities-gene-switches

Classroom Activities: Variations in the Clam Species Clamys sweetus (Lesson Plans/Lesson Activities) Description: An activity to engage students in thinking about the mechanism of natural selection Source: Howard Hughes Medical Institute | URL: http://www.hhmi.org/biointeractive/classroom-activities-variations-clam-species-clamys-sweetus

Clipbirds (Lesson Plans/Lesson Activities) Description: This variation on the classic bird beak activity demonstrates variation of beak size within a population and shows how the proportion of big-, medium-, and small-beaked birds changes in response to the available types of food. Source: Janulaw A, Scotchmoor J. UC Museum of Paleontology | URL: http://www.ucmp.berkeley.edu/education/lessons/clipbirds/

Color Variation Over Time in Rock Pocket Mouse Populations (Lesson Plans/Lesson Activities) Description: This activity provides an introduction to natural selection and the role of genetic variation by asking students to analyze illustrations of rock pocket mouse populations (dark/light fur) on different color substrates in the Sonoran Desert (light/dark) over time. Based on this evidence, and what they learn about variation and natural selection in the accompanying short film, students use this evidence to explain the change in the rock pocket mouse populations on the lava flow (dark substrate) over time. Source: Howard Hughes Medical Institute | URL: http://www.hhmi.org/biointeractive/color-variation-over-time-rock-pocket-mouse-populations

Comparing Species through the Fossil Record (Lesson Plans/Lesson Activities) Description: In this lesson, students begin to understand how physical features noted in the fossil record provide clues about the evolution of species. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/comparing-species-through-the-fossil-record/

Comparing Theories - Lamarck and Darwin (Lesson Plans/Lesson Activities) Description: This lesson provides an opportunity for students to compare the theories of two historically important evolutionary scientists: Jean Baptiste Lamarck and Charles Darwin. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/comparing-theories-lamarck-and-darwin/

Cystic Fibrosis: Exploration of Evolutionary Explanations for the High Frequency of a Common Disorder (Lesson Plans/Lesson Activities) Description: An expert authored advanced in-class exercise making and testing hypotheses to explain the high incidence of cystic fibrosis in certain populations Source: Genetics Society of America | URL: http://www.genetics-gsa.org/education/GSAPREP.2013.004.shtml

DNA to Darwin (Lesson Plans/Lesson Activities) Description: Allows students aged 16-19 to explore the molecular evidence for evolution through practical bioinformatics activities that use data analysis tools and molecular data. Source: NCBE, University of Reading | URL: http://www.dnadarwin.org/

Do You See What I See? (Lesson Plans/Lesson Activities) Description: A series of lesson plans and laboratory exercises exploring vision, color perception, color-blindness, diversity of vision across species, and how this diversity affects survival and reproduction. You may need to register to view the lesson plans, but the plans and registration is free. Source: Project NEURON, University of Illinois | URL: https://neuron.illinois.edu/units/do-you-see-what-i-see

Evolution - Variation + Selection and Time (Lesson Plans/Lesson Activities) Description: Lesson plans and quizzes on geologic time, misconceptions about natural selection and evolution, and sexual and asexual reproduction. Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/evolution/

Evolution and Medicine (Lesson Plans/Lesson Activities) Description: Lesson plans on how evolution informs human health, biomedical problems, and disease treatment Source: National Institutes of Health | URL: https://science.education.nih.gov/HighSchool/EvolutionAndMedicine

Evolution in a Ring (PDF 28.17 KB, Lesson Plans/Lesson Activities) Description: This lesson engages students in critical thinking about ring species and how the process of speciation occurs. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/evolution/lessons/irwinlessons.pdf

Evolution: Are There Really Missing Links? (PDF 13.91 KB, Lesson Plans/Lesson Activities) Description: This lesson focuses on applying evidence for evolutionary transitions to the general theory of evolution. Students can investigate how Darwin’s finches would adapt to simulated island environments, create an exhibit of “missing links” art, market a virtual natural history museum and more. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/evolution/lessons/benton2lessons.pdf

Evolution: Is It Fact and/or Theory? (PDF 26.75 KB, Lesson Plans/Lesson Activities) Description: This lesson examines patterns of change in nature, mechanisms of evolution, and factual evidence for evolution. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/evolution/lessons/lenskilessons.pdf

Exploring Learned and Innate Behavior (Lesson Plans/Lesson Activities) Description: This lesson explores the differences and similarities between innate and learned behavior and skills among humans and monkeys. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/exploring-learned-and-innate-behavior/

Extinction: Is It Inevitable? (PDF 28.17 KB, Lesson Plans/Lesson Activities) Description: This lesson explores the cycle of extinction and biotic recovery, with special emphasis on the causes of extinction. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/evolution/lessons/eldredge2lessons.pdf

Feathers - The Evolution of a Natural Miracle (Lesson Plans/Lesson Activities) Description: This lesson will help students learn more about the predictive power of scientific theories and fossil evidence by studying the evolution of feathers. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/feathers-evolution-natural-miracle/

Genes, Variation and Human History (Lesson Plans/Lesson Activities) Description: Interactive classroom activities on genetic variation Source: National Human Genome Research Institute | URL: http://www.genome.gov/25019893

Genetic Variation (PDF 492.28 KB, Lesson Plans/Lesson Activities) Description: A presentation on genetic variation intended for classroom use Source: National Human Genome Research Institute | URL: http://www.genome.gov/Pages/Education/Modules/GeneticVariation.pdf

Genetic Variation within the One Human Race (Lesson Plans/Lesson Activities) Description: Through this lesson, students will understand the pattern of genetic variation among humans. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/genetic-variation-within-one-human-race/

How Do New Species Form? (PDF 28.17 KB, Lesson Plans/Lesson Activities) Description: This lesson explores speciation, stasis, and change with activities that focus on comparing gradualism to punctuated equilibrium. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/evolution/lessons/eldredgelessons.pdf

Identifying Angiosperms (PDF 28.17 KB, Lesson Plans/Lesson Activities) Description: The lessons use photography and guided discussion to engage students in learning about classification, co-evolution, and the mystery of disappearing bees crucial to the pollination of flowers. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/genomics/lessons/Soltislessons.pdf

Introduction to Natural Selection (Lesson Plans/Lesson Activities) Description: This lesson is an introduction to natural selection. Students read an article on the evolution of finch species in Hawaii, answer questions about their reading, then complete a worksheet, group activity, and short written summary. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/introduction-to-natural-selection/

Mapping Change Over Time (Lesson Plans/Lesson Activities) Description: Collect information about the organisms alive at different times since the Earth formed. Discuss reasons for extinctions. Discuss advantages of change Source: Nuffield Foundation | URL: http://www.nuffieldfoundation.org/print/3210

mtDNA: So What Did You Inherit from Your Mom? (PDF 26.75 KB, Lesson Plans/Lesson Activities) Description: This lesson examines the structure and function of mitochondria and its role in evolution Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/evolution/lessons/ingmanlessons.pdf

Natural Selection (PDF 13.91 KB, Lesson Plans/Lesson Activities) Description: In this lesson plan students develop a conversation with Darwin, chart examples of natural selection in action, and speculate on the future of evolutionary history. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/evolution/lessons/futuymalessons.pdf

NIH Curriculum Supplements for High School: Human Genetic Variation (Lesson Plans/Lesson Activities) Description: Study the basics of human genetics, its potential to improve human health, and its application toward understanding and describing human evolution through these five lesson plans. Teacher guides are available for download. Source: National Institutes of Health, Office of Science Education | URL: https://science.education.nih.gov/HighSchool/HumanGeneticVariation

Nowhere to Hide (Lesson Plans/Lesson Activities) Description: Through the use of an interactive activity, this lesson focuses on the concept of natural selection. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/nowhere-to-hide/

Population Genetics (Lesson Plans/Lesson Activities) Description: In this lesson, students simulate what happens to a population containing sickle cell trait carriers over several generations in the presence of a high, medium, or low incidence of malaria. Students analyze class data to understand trends in each population and the selective forces at play. Students also review and discuss real-world data. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=5&l=3&c=0

Poster: Fossil Evidence and Evolution Description: A printable poster for your classroom. Students are challenged to place seven types of fossils into the proper geological era. Source: Howard Hughes Medical Institute | URL: http://www.hhmi.org/biointeractive/poster-fossil-evidence-and-evolution

Preserving Health through Biological Diversity (Lesson Plans/Lesson Activities) Description: This lesson advances student understanding of why diversity within and among species is important. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/preserving-health-through-biological-diversity/

Roots: The Ancestry of Modern People (PDF 13.91 KB, Lesson Plans/Lesson Activities) Description: This lesson examines the two main models of the origin of modern humans. Students can map the movements of early humans, consider what it takes to be a paleoanthropologist, write a news flash about Lucy’s discovery, chart a book plot about the adventures of an early hominid, and create a sketchbook of hominid fossils. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/evolution/lessons/johansonlessons.pdf

Selection In Action - Peppered Moths (Lesson Plans/Lesson Activities) Description: Use web-sourced material, maps and population data to explore the industrial melanism of the Peppered Moth Source: Nuffield Foundation | URL: http://www.nuffieldfoundation.org/print/3214

Sooty Selection (Lesson Plans/Lesson Activities) Description: A classroom activity adaptable for grades 3rd, 4th or 9th. Includes detailed teacher guide with common science standards, tips, quiz and PDF handout. Source: Ask A Biologist, Arizona Board of Regents | URL: https://askabiologist.asu.edu/experiments/sooty-selection

Sun, Natural Selection, and Skin Color (Lesson Plans/Lesson Activities) Description: In this lesson, students explore how the intensity of the sun at different latitudes has contributed to variations in human skin color. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/sun-natural-selection-and-skin-color/

Teaching Materials: Understanding Evolution Description: Resources for teaching evolutionary patterns, processes, and theory Source: The University of California Museum of Paleontology, and the Regents of University of California | URL: http://evolution.berkeley.edu/evolibrary/teach/index.php

The History of Evolutionary Theory (Lesson Plans/Lesson Activities) Description: This lesson provides high-school students with an introduction to a more detailed study of evolution by focusing on the historical origins of Darwin theory and the ideas that came before it. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/the-history-of-evolutionary-theory/

The Teacher-Friendly Guide™ to Evolution Using Bivalves as a Model Organism Description: A guide providing teachers with background information to support existing curricula and aid in teaching the concept of evolution. Source: Paleontological Research Institution | URL: http://bivalves.teacherfriendlyguide.org/index.php?option=com_content&view=article&id=41&Itemid=101

Visualizing Gene-Expression Patterns Description: A slide show with video clips illustrating how scientists detect when a gene is being expressed in tissues Source: Howard Hughes Medical Institute | URL: http://media.hhmi.org/biointeractive/click/Visualizing_Gene_Expression/01.html

What Makes Honey Bees Work Together? (Lesson Plans/Lesson Activities) Description: A series of lesson plans exploring how genes and environment affect behavior, as well as introduces students to research tools used to investigate gene expression. You may need to register to view the lesson plans, but the plans and registration is free. Source: Project NEURON, University of Illinois | URL: https://neuron.illinois.edu/units/what-makes-honey-bees-work-together

GENETIC CONDITIONS A Recipe for Traits (PDF 1,129.11 KB , Lesson Plans/Lesson Activities) Description: Students create and decode DNA for mans best friend to observe how variations in DNA lead to the inheritance of different traits. Strips of paper that represent DNA are randomly selected and used to assemble the dogs DNA. Students read the DNA and create a drawing of their pet, and compare it with others in the class to check for similarities and differences. Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/heredity/files/Traits-Recipe.pdf

Analyzing Chromosomes (PDF 7,056.8 KB, Lesson Plans/Lesson Activities) Description: Students learn about chromosome analysis by completing a partial karyotype and assess the karyotype for anomalies. Students practice sharing bad news to parents. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/AdventuresInKaryotyping_L2.pdf

Cancer Risks (Lesson Plans/Lesson Activities) Description: In this lesson students examine environmental and hereditary factors that increase the chance of developing cancer. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/cancer-risks/

Cell Biology and Cancer (Lesson Plans/Lesson Activities) Description: This NIH Curriculum Supplement is for high school teachers. It includes lesson plans, class activities, and videos. Source: BSCS and Videodiscovery, Inc. | URL: https://science.education.nih.gov/HighSchool/CellBiologyAndCancer

Creating Genetic Counselor Pamphlets (Lesson Plans/Lesson Activities) Description: After discussing the benefits and potential misuses of prenatal genetic testing, students in grades 9-12 research a particular genetic disorder and then create pamphlets about the disorder from a genetic counselor's point of view. Source: PBS & WGBH Educational Foundation | URL: http://www.pbs.org/inthebalance/archives/ourgenes/lesson_pamphlets.html

Cystic Fibrosis: Exploration of Evolutionary Explanations for the High Frequency of a Common Disorder (Lesson Plans/Lesson Activities) Description: An expert authored advanced in-class exercise making and testing hypotheses to explain the high incidence of cystic fibrosis in certain populations Source: Genetics Society of America | URL: http://www.genetics-gsa.org/education/GSAPREP.2013.004.shtml

DNA Repair - Exploring the 2015 Nobel Prize Winning work of two NC scientists (Lesson Plans/Lesson Activities) Description: This University of North Carolina teaching module explores several built-in protection mechanisms our bodies use to prevent and repair damage to DNA. In 2015, Dr. Aziz Sancar from UNC Chapel Hill and Dr. Paul Modrich from Duke University were awarded the Nobel Prize in Chemistry for their work on understanding DNA repair. Students will extract their own DNA from saliva and analyze REAL data from Dr. Sancars Nobel-winning research. Source: UNC School of Medicine | URL: http://ncdnaday.org/learn-more/resources-2/

Do You See What I See? (Lesson Plans/Lesson Activities) Description: A series of lesson plans and laboratory exercises exploring vision, color perception, color-blindness, diversity of vision across species, and how this diversity affects survival and reproduction. You may need to register to view the lesson plans, but the plans and registration is free. Source: Project NEURON, University of Illinois | URL: https://neuron.illinois.edu/units/do-you-see-what-i-see

Does Sunscreen Protect My DNA? (Lesson Plans/Lesson Activities) Description: Explore how effectively different sunscreens protect yeast cells from damage caused by ultraviolet (UV) radiation. Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/labs/#item3

Environment and Gene Interactions Cancer Module (PDF 3,266.9 KB, Lesson Plans/Lesson Activities) Description: This PowerPoint presentation offers a detailed introduction to genetic and environmental risk factors for cancer. Source: The University of Texas MD Anderson Cancer Center | URL: http://www.niehs.nih.gov/health/assets/docs_a_e/environment_and_gene_interactions_cancer_module.pdf

Exploring Twin Studies (PDF 1,037.91 KB, Lesson Plans/Lesson Activities) Description: This lesson challenges students to list complex traits, and includes a reading on genetic and environmental influences in type II diabetes. Students are challenged to design a study to determine the relative contribution of environment and genetics for a given trait/condition. Finally, students are introduced to the most common design used for this purpose, the twin study. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/NatureNurture_L1.pdf

From Genomes of Species (PDF 28.17 KB, Lesson Plans/Lesson Activities) Description: Students create a play, interview a medical patient or doctor, explore advances in genomics at a local university, and consider the feasibility and ethical use of bonobos as a model organism. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/genomics/lessons/hhmilessons.pdf

Gene Therapy - Molecular Bandage (Lesson Plans/Lesson Activities) Description: A module with six engaging lesson plans and activities on gene therapy. Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/genetherapy/

Genetic Disease Webquest (Lesson Plans/Lesson Activities) Description: A game perfect for the classroom. Your students become members of an elite medical investigation team, called into action because of a high number of mysterious infant deaths in a remote community in New Mexico. It is unclear whether the deaths are a result of an infectious disease or an inherited gene. As part of the investigation, your students must determine the cause of the deaths and what can be done to save the lives of other children in this community. Source: National Academy of Sciences | URL: https://koshland-science-museum.org/explore/genetic-disease-webquest-student

Genetics Education Materials for School Success - Cystic Fibrosis Description: This robust guide for teachers and parents aims to help children with genetic conditions succeed in school-life. Source: The New England Genetics Collaborative | URL: https://www.gemssforschools.org/conditions/cystic-fibrosis/default

Genetics Education Materials for School Success - Down syndrome Description: This robust guide for teachers and parents aims to help children with genetic conditions succeed in school-life. Source: The New England Genetics Collaborative | URL: https://www.gemssforschools.org/conditions/down/default

Genetics Education Materials for School Success - Sickle Cell Disease Description: This robust guide for teachers and parents aims to help children with genetic conditions succeed in school-life. Source: The New England Genetics Collaborative | URL: https://www.gemssforschools.org/conditions/sickle-cell-disease/default

Genome Editing and CRISPR Lesson Plan (Lesson Plans/Lesson Activities) Description: Through this lesson plan you will explore with your students how advances in our ability to change genomes may impact individuals and society. Source: Personal Genetics Education Project | URL: http://pged.org/lesson-plans/#CRISPR

Genomics and Human Identity (Lesson Plans/Lesson Activities) Description: Bring genomics to life for your high school students with this lesson plan. The lessons encourage hands-on, inquirybased learning and include genomic concepts and research projects. Source: National Human Genome Research Institute and the Smithsonian National Museum of Natural History | URL: https://unlockinglifescode.org/connections/newsletter/genomics-and-human-identity

Genomics and Inheritance (Lesson Plans/Lesson Activities) Description: This University of North Carolina teaching module teaches students about the human genome and what makes us each unique, how traits are inherited, and how Genome Wide Association Studies (GWAS) are helping to identify genes responsible for complex human diseases. Hands on activities include the Genetic Wheel (which shows how inherited traits make each of us incredibly unique) and a GWAS activity where students get to identify a genetic marker contributing to a human disease. Source: UNC School of Medicine | URL: http://ncdnaday.org/learn-more/resources-2/

Good Cells Gone Bad (PDF 102.28 KB, Lesson Plans/Lesson Activities) Description: Use this simple activity to teach your students about differences between a healthy cell and a cancerous one. Source: Arizona Cancer Center at the University of Arizona | URL: http://www.niehs.nih.gov/health/assets/docs_f_o/good_cells_gone_bad_2001.pdf

Inheriting Sickle Cell Anemia (Lesson Plans/Lesson Activities) Description: Students learn about the most commonly inherited mutation in hemoglobin beta that causes sickle cell anemia. Students learn how to construct a pedigree from family history information, will practice generating RNA and protein sequences from a DNA sequence, and will connect changes in DNA sequence to changes in protein behavior to symptoms of an inherited disease. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=5&l=2&c=0

Inside Cancer - Teacher Center Description: Use this Web tool to build classroom presentations, find lesson plans, and align content with national and local education standards. Source: Dolan DNA Learning Center | URL: http://teachercenter.insidecancer.org/

Introduction to Heredity and Traits (Lesson Plans/Lesson Activities) Description: Five easy-to-implement clasroom activities teach the basics of heritable traits. Three take-home activities help students share what they're learning with their families. Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/heredity/

Juniors Family Tree (PDF 122.19 KB, Lesson Plans/Lesson Activities) Description: The learner will trace the family history of a horse named Junior as they explore why he has the characteristic traits that he does. The lesson includes an interview with a horse breeder and demonstrates how traits are passed from generation to generation. The lesson makes it clear that each parent contributes to the traits of the offspring, demonstrating cause and effect. Source: Agriculture in the Classroom, University of Utah | URL: http://cals.arizona.edu/fps/sites/cals.arizona.edu.fps/files/education/juniors_tree.pdf

KRAS: Cancer Mutation (Lesson Plans/Lesson Activities) Description: Use real genomic data to find mutations in a gene associated with pancreatic, lung and colorectal cancers. Source: Genome Research Limited and Wellcome Trust Sanger Institute | URL: http://www.yourgenome.org/activities/kras-cancer-mutation

Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics (Lesson Plans/Lesson Activities) Description: A lesson that requires students to work through a series of questions pertaining to the genetics of sickle cell disease and its relationship to malaria. These questions will probe students' understanding of Mendelian genetics, probability, pedigree analysis, and chi-square statistics. Source: Howard Hughes Medical Institute | URL: https://www.hhmi.org/biointeractive/mendelian-genetics-probability-pedigree-and-chi-square-statistics

Personalized Medicine (aka Pharmacogenomics) (Lesson Plans/Lesson Activities) Description: In this teaching module students will learn about the concept of personalized medicine; how differences in our genes affect whether a drug treatment will be successful or have serious side effects, and how we can use this information to customize treatments for individual patients. Students will participate in a hands-on activity to further demonstrate how subtle genetic differences affect a patients response to medication. Source: UNC School of Medicine | URL: http://ncdnaday.org/learn-more/resources-2/

Population Genetics (Lesson Plans/Lesson Activities) Description: In this lesson, students simulate what happens to a population containing sickle cell trait carriers over several generations in the presence of a high, medium, or low incidence of malaria. Students analyze class data to understand trends in each population and the selective forces at play. Students also review and discuss real-world data. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=5&l=3&c=0

Race and Genes (Lesson Plans/Lesson Activities) Description: Visible traits of the human phenotype associated with specific races are influenced by a common set of genes all humans share, the genome, and environmental interactions. Culture determines how they are perceived. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/race-and-genes/

Rare Diseases and Scientific Inquiry (Lesson Plans/Lesson Activities) Description: In this NIH curriculum supplement for middle school, students explore how scientists use inquiry to research rare diseases and treatments and to further understand the workings of the human body. The supplement contains two weeks of lessons that are easily integrated into your curriculum and are aligned to national and state standards. Source: National Institutes of Health | URL: https://science.education.nih.gov/MiddleSchool/RareDiseasesAndScientificInquiry

Retinoblastoma, Cystic Fibrosis, and Body Mass Index, Oh My! (PDF 196.72 KB, Lesson Plans/Lesson Activities) Description: Building on their intuitive understanding of twin study correlations, students analyze subsets of data to determine how strong the environmental and genetic influences are for three different traits/conditions. Students use mean, standard deviation, and Pearson correlation coefficient to describe and make meaning of their data. They also graph their data and correlations, and compare the results from their subset of data to the results of a group using a different subset of the data. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/NatureNurture_L2_corrected.pdf

Skin Cancer 1 - Exposing Healthy Skin to the Sun (Lesson Plans/Lesson Activities) Description: Use this lesson plan to give your students an understanding of the science behind keeping their skin healthy. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/skin-cancer-1/

Skin Cancer 2 - Types, Prevention, and Detection (Lesson Plans/Lesson Activities) Description: This lesson is on skin cancer, its different types, how it can be detected, and how it can be prevented. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/skin-cancer-2/

Sun and Skin (Lesson Plans/Lesson Activities) Description: In this lesson, students discuss what they already know about the impact sun exposure has on their skin and what they typically do to protect themselves. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/sun-skin/

Symptoms of a Mystery Disease (PDF 305.56 KB, Lesson Plans/Lesson Activities) Description: Students read a description of a patient with a mysterious disease and must decide what tests might help them understand the disease. Then, they investigate how the patient's oddly shaped blood cells (discovered in a blood test) lead to his symptoms. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/SickleCellAnemia_L1.pdf

Technological Advances in Health (Lesson Plans/Lesson Activities) Description: Students will learn how technology influences human existence by examining the benefits and risks of different biotechnological advances. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/technological-advances-in-health/

The Chernobyl Disaster (Lesson Plans/Lesson Activities) Description: Students explore how a nuclear accident can affect biological systems. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/the-chernobyl-disaster/

The Science of Cancer (Lesson Plans/Lesson Activities) Description: Visit this Web page to find a collection of lesson plans, tool, science updates, and videos about cancer and cancer research. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/collections/science-cancer/

Traits Activities (Lesson Plans/Lesson Activities) Description: Activities on genetic traits and disease risk, including traits bingo, inventorying common traits among your students, and tracking traits through three generations of ginger-bread people. Source: Genetics Science Learning Center at the University of Utah | URL: http://learn.genetics.utah.edu/content/basics/activities/

Variation in Human Skin Color (Lesson Plans/Lesson Activities) Description: In this lesson, students explore the factors that control variation in human skin color and the implications of this information for human society. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/variation-in-human-skin-color/

Who Gets Sick? (Lesson Plans/Lesson Activities) Description: Students learn that disease is influenced by genetic factors. They also learn about how the likelihood of inheriting gene mutations for a particular disease is linked to the branches of the human family tree from which one descends. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/health-connections/

HEREDITY/INHERITANCE PATTERNS A Mendel Seminar (Lesson Plans/Lesson Activities) Description: Students learn about Gregor Mendel. Mendel discovered the process of biological evolution, how recessive and dominant traits are passed on. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/a-mendel-seminar/

A Recipe for Traits (PDF 1,129.11 KB , Lesson Plans/Lesson Activities) Description: Students create and decode DNA for mans best friend to observe how variations in DNA lead to the inheritance of different traits. Strips of paper that represent DNA are randomly selected and used to assemble the dogs DNA. Students read the DNA and create a drawing of their pet, and compare it with others in the class to check for similarities and differences. Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/heredity/files/Traits-Recipe.pdf

Asexual vs Sexual Reproduction (Lesson Plans/Lesson Activities) Description: An illustrated article, video, and practice problems teaching asexual and sexual reproduction, including how to distinguish between sexual and asexual reproduction, the different types of asexual reproduction, and how plants and animals reproduce sexually. Source: cK-12 Foundation | URL: http://www.ck12.org/book/CK-12-Life-Science-Concepts-For-Middle-School/section/2.20/

Asparagus Odor Description: Chances are there is a kind of food you like that at least one friend finds disgusting, and vice versa. The same goes for smells. And while many factors undoubtedly affect our personal tastes, this Science Update examines how scientists are learning that things simply smell and taste different to different people. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/science-news/science-updates/asparagus-odor/

Basic Probability and Chi-Squared Tests (Lesson Plans/Lesson Activities) Description: An expert authored advanced in-class exercise teaching critical skills for classic genetic analysis, including probability, making predictions, and assessment. Source: Genetics Society of America | URL: http://www.genetics-gsa.org/education/GSAPREP.2013.005.shtml

Can you taste PTC? (PDF 1,989.26 KB, Lesson Plans/Lesson Activities) Description: In this lesson, students use a Single Nucleotide Polymorphism (SNP) kit to determine their genotype for the TAS2R38 gene. While waiting for their results, students also test their PTC tasting ability (phenotype). The class then analyzes both phenotype and genotype data to determine which allele is the taster allele and which allele is the non-taster allele. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/GeneticsOfTaste_L3_corrected.pdf

Complex Trait Genetics (PDF 2,053.35 KB, Lesson Plans/Lesson Activities) Description: The lesson begins with students contrasting histograms of a discrete trait (sex) and a continuous trait (height). Students then explore polygenic inheritance of height with a three-gene system, in the process modeling segregation of alleles and independent assortment during meiosis, as well as sexual reproduction. Finally, students discuss limitations of their model and add environmental influences. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/ComplexTraitGenetics_L1.pdf

Constructing a Pedigree (PDF 360.58 KB, Lesson Plans/Lesson Activities) Description: This lesson uses the Simpsons to introduce the utility of pedigrees in studying family health. Students then apply their knowledge by acting as genetic counselors to construct and analyze a pedigree based on a case study of new or perspective parents who are concerned about the health of their child. As homework, students also have the opportunity to apply pedigree construction to their own family health history. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/AdventuresInKaryotyping_L1.pdf

DNA from the Beginning Description: An animated primer of 75 experiments that made modern genetics Source: Cold Spring Harbor Laboratory | URL: http://www.dnaftb.org/

Do You See What I See? (Lesson Plans/Lesson Activities) Description: A series of lesson plans and laboratory exercises exploring vision, color perception, color-blindness, diversity of vision across species, and how this diversity affects survival and reproduction. You may need to register to view the lesson plans, but the plans and registration is free. Source: Project NEURON, University of Illinois | URL: https://neuron.illinois.edu/units/do-you-see-what-i-see

Exploring Twin Studies (PDF 1,037.91 KB, Lesson Plans/Lesson Activities) Description: This lesson challenges students to list complex traits, and includes a reading on genetic and environmental influences in type II diabetes. Students are challenged to design a study to determine the relative contribution of environment and genetics for a given trait/condition. Finally, students are introduced to the most common design used for this purpose, the twin study. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/NatureNurture_L1.pdf

Gene Puzzles (Lesson Plans/Lesson Activities) Description: In this lesson, students will examine a fictional pedigree and determine which gene is responsible for a given trait Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/gene-puzzles/

Gene U - Genetics and Inheritance Description: Lesson guides, videos, slides, and other teaching resources on genes and inheritance. Teacher guide includes lesson plans using domestic dogs as a model to teach core genetic concepts. Source: Baylor College of Medicine Center for Educational Outreach | URL: http://www.bioedonline.org/lessons-and-more/resource-collections/gene-u-genetics-and-inheritance/

Genes, Environments, and Behavior (Lesson Plans/Lesson Activities) Description: This lesson focuses on how behavior is defined by scientists and on the genetic and environmental forces that interact to shape behavior. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/genes-environments-and-behavior-1/

Genes, Environments, and Behavior 2 (Lesson Plans/Lesson Activities) Description: This lesson helps students understand how scientists study the genetic and environmental factors that interact to produce variation in behavior across a population. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/genes-environments-and-behavior-2/

Genomics and Human Identity (Lesson Plans/Lesson Activities) Description: Bring genomics to life for your high school students with this lesson plan. The lessons encourage hands-on, inquirybased learning and include genomic concepts and research projects. Source: National Human Genome Research Institute and the Smithsonian National Museum of Natural History | URL: https://unlockinglifescode.org/connections/newsletter/genomics-and-human-identity

Genomics and Inheritance (Lesson Plans/Lesson Activities) Description: This University of North Carolina teaching module teaches students about the human genome and what makes us each unique, how traits are inherited, and how Genome Wide Association Studies (GWAS) are helping to identify genes responsible for complex human diseases. Hands on activities include the Genetic Wheel (which shows how inherited traits make each of us incredibly unique) and a GWAS activity where students get to identify a genetic marker contributing to a human disease. Source: UNC School of Medicine | URL: http://ncdnaday.org/learn-more/resources-2/

Genotype Versus Phenotype Description: A song on genotype and phenotype by Greg Crowther, an Acting Assistant Professor at the University of Washington. Source: Greg Crowther | URL: http://faculty.washington.edu/crowther/Misc/Songs/genotype.shtml

Harry Potter's World Description: Activities for teaching basic genetic concepts as well as characteristics of complex traits Source: National Library of Medicine | URL: http://www.nlm.nih.gov/exhibition/harrypottersworld/science.html

Health Family History Module (Lesson Plans/Lesson Activities) Description: Engage students in learning about family health history and the connection between genetics and health. Through this module students will understand basic information about common diseases and disease risk, assess personal risk, and devise ways to reduce disease risk. Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/familyhistory/

Introducing Ideas About Inheritance (Lesson Plans/Lesson Activities) Description: A classroom exercise illustrating genetic vs environmental influences on human traits Source: Nuffield Foundation | URL: http://www.nuffieldfoundation.org/print/3196

Introduction to Complex Inheritance (Lesson Plans/Lesson Activities) Description: At the beginning of this lesson, students' prior understanding of non-Mendelian (complex) inheritance, the nature of genetic information, and how genetic information can be used is assessed using a Genetic Pretest and a creative writing assignment. Then, students learn about some of the many complexities of inheritance of non-Mendelian traits. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=2&l=1&c=0

Introduction to Heredity and Traits (Lesson Plans/Lesson Activities) Description: Five easy-to-implement clasroom activities teach the basics of heritable traits. Three take-home activities help students share what they're learning with their families. Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/heredity/

Investigating Reproductive Strategies (Lesson Plans/Lesson Activities) Description: A lesson plan comparing sexual and asexual reproduction in several organisms. Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/evolution/files/ReproductiveStrategies.pdf

It is Genetic--Or Is It? (Lesson Plans/Lesson Activities) Description: This lesson for grades 9-12 explores the age-old discussion of nature vs. nurture: how much of our individuality is based on inheritance, and how much is shaped by our environment? Students explore different traits as genetic or environmental and then discuss issues of accountability for genetically-influenced personality traits. Source: PBS & WGBH Educational Foundation | URL: http://www.pbs.org/inthebalance/archives/ourgenes/lesson_genetic.html

Juniors Family Tree (PDF 122.19 KB, Lesson Plans/Lesson Activities) Description: The learner will trace the family history of a horse named Junior as they explore why he has the characteristic traits that he does. The lesson includes an interview with a horse breeder and demonstrates how traits are passed from generation to generation. The lesson makes it clear that each parent contributes to the traits of the offspring, demonstrating cause and effect. Source: Agriculture in the Classroom, University of Utah | URL: http://cals.arizona.edu/fps/sites/cals.arizona.edu.fps/files/education/juniors_tree.pdf

Multifactorial Traits (PDF 2.53 MB, Lesson Plans/Lesson Activities) Description: Detailed book chapter on multifactorial traits with practice problems Source: McGraw-Hill Higher Education | URL: http://highered.mheducation.com/sites/dl/free/0072995394/518219/lew95394_ch07_131_150_modified.pdf

Nature and Nurture (Lesson Plans/Lesson Activities) Description: In this lesson, students develop an understanding of the role both nature and nurture play in determining human traits. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/nature-and-nurture/

Pets - Oh Behave (Lesson Plans/Lesson Activities) Description: This lesson helps students develop an understanding of how innate and learned behaviors and the environment determine behavior. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/pets-oh-behave/

Pigeonetics Guide (Lesson Plans/Lesson Activities) Description: This game, with 26 pigeon-breeding puzzles of increasing complexity, helps students learn about mechanisms of inheritance, and it brings together often disconnected concepts from Mendelian inheritance and molecular genetics. Source: Genetics Science Learning Center at the University of Utah | URL: http://learn.genetics.utah.edu/content/pigeons/pigeonetics/

Race and Genes (Lesson Plans/Lesson Activities) Description: Visible traits of the human phenotype associated with specific races are influenced by a common set of genes all humans share, the genome, and environmental interactions. Culture determines how they are perceived. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/race-and-genes/

Reproduction (Lesson Plans/Lesson Activities) Description: The learner explores ways in which organisms reproduce, and discusses the role that reproduction plays in the cycle of life. By watching short videos and participating in follow-up discussion, students observe that 1. No individual organism lives forever and in order to continue species, organisms must pass their genetic instructions on to the next generation. 2. They learn that organisms reproduce asexually, by dividing and producing two identical copies of themselves. 3. They learn that many plants reproduce sexually, often using complex strategies that have evolved over millions of years. 4. They explore the pros and cons of asexual and sexual reproduction and the reasons both strategies persist. Source: PBS & WGBH Educational Foundation | URL: http://ca.pbslearningmedia.org/resource/tdc02.sci.life.repro.lp_reproduce/reproduction/

Sex Determination (Lesson Plans/Lesson Activities) Description: This lesson explores sex determination in mammals. Students first share their conceptions about the genetics of sex determination, then using normal and abnormal human karyotypes, students hone in on their hypothesis. The case of XY females is used to explain the presence of the SRY gene on the Y chromosome, which must produce active protein in order for a male to develop. The lesson ends by exploring other sex-determination systems in animals and their similarities and differences. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=1&l=1&c=0

Sex-Linked Inheritance (Lesson Plans/Lesson Activities) Description: In this lesson, students take on the role of scientists as they explore the results of T.H. Morgan's famous white-eyed flies experiment. Students construct Punnett squares for different hypotheses in order to determine which hypothesis fits Morgan's actual results. Students work toward an understanding that white eyes in flies are an X-linked recessive trait. They explore the hallmarks of this type of sex-linked inheritance as well as the much rarer types, X-linked dominant and Y-linked. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=1&l=2&c=0

The Chernobyl Disaster (Lesson Plans/Lesson Activities) Description: Students explore how a nuclear accident can affect biological systems. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/the-chernobyl-disaster/

The Mystery of Calico Cats (Lesson Plans/Lesson Activities) Description: In this lesson, students explore the genetics and epigenetics behind calico cats. Using sex-linked Punnett squares, students must determine what the genotype for coat color is for calico cats. The class then discusses why dosage compensation for the X chromosome is necessary in females and how that relates to the patchy appearance and female sex of calico cats. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=1&l=3&c=0

Traits Activities (Lesson Plans/Lesson Activities) Description: Activities on genetic traits and disease risk, including traits bingo, inventorying common traits among your students, and tracking traits through three generations of ginger-bread people. Source: Genetics Science Learning Center at the University of Utah | URL: http://learn.genetics.utah.edu/content/basics/activities/

Variation in Human Skin Color (Lesson Plans/Lesson Activities) Description: In this lesson, students explore the factors that control variation in human skin color and the implications of this information for human society. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/variation-in-human-skin-color/

What Makes Honey Bees Work Together? (Lesson Plans/Lesson Activities) Description: A series of lesson plans exploring how genes and environment affect behavior, as well as introduces students to research tools used to investigate gene expression. You may need to register to view the lesson plans, but the plans and registration is free. Source: Project NEURON, University of Illinois | URL: https://neuron.illinois.edu/units/what-makes-honey-bees-work-together

Who Gets Sick? (Lesson Plans/Lesson Activities) Description: Students learn that disease is influenced by genetic factors. They also learn about how the likelihood of inheriting gene mutations for a particular disease is linked to the branches of the human family tree from which one descends. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/health-connections/

Wild Type and Mutant (Lesson Plans/Lesson Activities) Description: A lesson plan introducing the common fruit fly as a model organism, as well as phenotype, genotype, and genetic inheritance patterns. Source: Exploratorium | URL: https://www.exploratorium.edu/imaging_station/activities/classroom/wild_mutant/ca_wild_mutant.php

Your Family Health History - A DNA Day Activity (PDF 119.18 KB, Lesson Plans/Lesson Activities) Description: A PowerPoint presentation on using a pedigree to record your family health history Source: National Human Genome Research Institute | URL: http://www.genome.gov/Pages/Education/Modules/YourFamilyHealthHistory.pdf

TOP ISSUES IN GENETICS Advanced Bioinformatics: Genetic Research (Lesson Plans/Lesson Activities) Description: A curriculum unit exploring how bioinformatics is used to perform genetic research. Specifically, the bioinformatics tools of BLAST, ORFinder, ClustalW and Cn3D are used to analyze genetic sequences. Source: The Northwest Association for Biomedical Research | URL: https://www.nwabr.org/teacher-center/advanced-bioinformatics-genetic-research#overview

Animals in Research (Lesson Plans/Lesson Activities) Description: A curriculum supplement introducing the complex topic of animal research using structured discussion, stakeholder activities, case studies, and ethical frameworks. Source: The Northwest Association for Biomedical Research | URL: https://www.nwabr.org/teacher-center/animals-research#overview

Athletics and Genetics (Lesson Plans/Lesson Activities) Description: In this lesson, students are asked to consider how their own genetic information might influence their athletic path. Source: Personal Genetics Education Project | URL: http://pged.org/lesson-plans/#athletics

Barcoding 101 (Lesson Plans/Lesson Activities) Description: DNA barcoding provides a practical way to bring open-ended experimentation into biology classes. Find all you need to bring DNA barcoding to your classroom. Source: Dolan DNA Learning Center | URL: http://www.dnabarcoding101.org/

Barcoding 101 Classroom Downloads Description: Download lesson plans, worksheets, DNA barcoding instructions, animations and more to bring DNA barcoding to your classroom. Source: Dolan DNA Learning Center | URL: http://www.dnabarcoding101.org/resources/index.html

Bioethics 101 (Lesson Plans/Lesson Activities) Description: A five-lesson introductory course to help science teachers in guiding their students to analyze issues using scientific facts, ethical principles, and reasoned judgment Source: The Northwest Association for Biomedical Research | URL: https://www.nwabr.org/teacher-center/bioethics-101#overview

Bioinformatics (PDF 13.91 KB, Lesson Plans/Lesson Activities) Description: Students use inquiry skills to make and test predictions about genes and their corresponding proteins, understand the use of bioinformatics programs, and pursue their own studies of genes and proteins of interest to them. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/genomics/lessons/gregorylessons.pdf

Cracking the Genetic Code (Lesson Plans/Lesson Activities) Description: This lesson explores what the knowledge of DNA can tell us about ourselves and other organisms and species. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/cracking-the-genetic-code/

Creating Genetic Counselor Pamphlets (Lesson Plans/Lesson Activities) Description: After discussing the benefits and potential misuses of prenatal genetic testing, students in grades 9-12 research a particular genetic disorder and then create pamphlets about the disorder from a genetic counselor's point of view. Source: PBS & WGBH Educational Foundation | URL: http://www.pbs.org/inthebalance/archives/ourgenes/lesson_pamphlets.html

Debating the Ethical and Legal Implications of Genetic Testing (PDF 904.59 KB, Lesson Plans/Lesson Activities) Description: Students explore the difference between ethical and legal issues and use an analytical framework to work through an ethical scenario before researching and debating two genetic testing scenarios. Additional chapters from DNA: Promise and Peril (McCabe, Linda L. and McCabe, Edward R.B. Regents of the University of California Press, 2008.) provide a starting point for their research. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/ELSI_L3.pdf

Decoding the Flu (Lesson Plans/Lesson Activities) Description: This classroom activity teaches how to read and interpret information stored in DNA. It makes use of personal response systems (clickers) and a PowerPoint presentation. The story centers on a CDC student intern, Jason. While working with a CDC team in Mexico, Jason is the only person who does not get sick from a new strain of flu. It is up to Jason to use molecular data collected from different local strains of flu to identify which one may be causing the illness. Source: National Center for Case Study Teaching in Science, University at Buffalo | URL: http://sciencecases.lib.buffalo.edu/cs/collection/detail.asp?case_id=597&id=597

Direct-to-Consumer Genetic Testing (Lesson Plans/Lesson Activities) Description: This lesson provides students the opportunity to explore the excitement and challenges related to the direct-toconsumer (DTC) genetic testing industry. How do consumers react to genetic information gleaned from DTC services? What information can be learned through a DTC test, and do consumers need or want a doctor or genetic counselor to access this information? Source: Personal Genetics Education Project | URL: http://www.pged.org/lesson-plans/#DTC

Direct-to-Consumer Genetic Testing (196 KB, Lesson Plans/Lesson Activities) Description: Students explore common complex traits and diseases by creating a FAQ sheet about a trait or disease listed in their fictitious 23andMe "Spit Kit" results. They also explore the caveats of the genetic testing offered by 23andMe for their trait or disease of interest, and in small groups, decide how relevant they think the results are. This leads to a class discussion about the benefits and drawbacks of direct-to-consumer genetic testing. Finally, students read about the pervasiveness of genetic determinism attitudes in modern society and the unethical behavior these attitudes have led to in the past. Source: The American Society of Human Genetics | URL: http://www.ashg.org/education/gena/ELSI_L2.pdf

DNA Barcoding and the International Barcode of Life (iBOL) Project Description: A rich source of teaching materials and instructional guides for one of the largest biodiversity genomics initiatives Source: Coastal Marine Biolabs | URL: http://www.educationandbarcoding.org/getting_started.php

DNA from the Beginning Description: An animated primer of 75 experiments that made modern genetics Source: Cold Spring Harbor Laboratory | URL: http://www.dnaftb.org/

DNA Repair - Exploring the 2015 Nobel Prize Winning work of two NC scientists (Lesson Plans/Lesson Activities) Description: This University of North Carolina teaching module explores several built-in protection mechanisms our bodies use to prevent and repair damage to DNA. In 2015, Dr. Aziz Sancar from UNC Chapel Hill and Dr. Paul Modrich from Duke University were awarded the Nobel Prize in Chemistry for their work on understanding DNA repair. Students will extract their own DNA from saliva and analyze REAL data from Dr. Sancars Nobel-winning research. Source: UNC School of Medicine | URL: http://ncdnaday.org/learn-more/resources-2/

Does Our Background Shape Our Thinking About Environmental Issues? (PDF 175.67 KB, Lesson Plans/Lesson Activities) Description: A lesson guide exploring personal attitues and impressions of environmental issues Source: Smithsonian National Museum of Natural History | URL: http://anthropology.si.edu/outreach/Teaching_Activities/pdf/EnvironmentalActivity.pdf

Ethics and Reproductive Issues - The Dilemma of Choice (Lesson Plans/Lesson Activities) Description: This lesson introduces students to the ethical implications of using our growing knowledge about the human genome to improve our personal and public health. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/ethics-and-reproductive-issues/

Ethics Primer (Lesson Plans/Lesson Activities) Description: Engaging, interactive, and classroom-friendly lesson ideas for integrating ethical issues into a science classroom. Source: The Northwest Association for Biomedical Research | URL: https://www.nwabr.org/teacher-center/ethics-primer#overview

Exploring Bioethics (Lesson Plans/Lesson Activities) Description: Curriculum supplement, teacher guide, and support materials on bioethics Source: National Institutes of Health | URL: https://science.education.nih.gov/HighSchool/ExploringBioethics

Exploring Learned and Innate Behavior (Lesson Plans/Lesson Activities) Description: This lesson explores the differences and similarities between innate and learned behavior and skills among humans and monkeys. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/exploring-learned-and-innate-behavior/

Forensics (Lesson Plans/Lesson Activities) Description: This module teaches shows students how DNA is analyzed by forensic scientists in order to link a DNA sample to a particular individual. To do this, forensic scientists use powerful molecular biology techniques such as PCR, restriction digests and gel electrophoresis. To learn more about DNA and how it is used by forensic scientists, students will isolate their own DNA from saliva. Using their new-found understanding of DNA and forensics techniques, students will help solve the case of the missing mascot. Source: UNC School of Medicine | URL: http://ncdnaday.org/learn-more/resources-2/

Genes, Environment and Genetic Complexity: Aggression in Humans (Lesson Plans/Lesson Activities) Description: Questions about whether genetics can, in part, explain violent, aggressive behavior in humans are not new. Recent episodes of large-scale violence, whether in schools or other public places, have renewed discussion about the intersection of crime, mental health and genetics. In this lesson, students are asked to examine popular but incorrect ideas related to the idea that a single gene or even set of genes can cause humans to behave aggressively. Source: Personal Genetics Education Project | URL: http://pged.org/lesson-plans/#aggression

Genes, Environments, and Behavior Description: This lesson focuses on how behavior is defined by scientists and on the genetic and environmental forces that interact to shape behavior. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/genes-environments-and-behavior-1/

Genes, Environments, and Behavior 2 Description: This lesson helps students understand how scientists study the genetic and environmental factors that interact to produce variation in behavior across a population. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/genes-environments-and-behavior-2/

Genetic Disease Webquest (Lesson Plans/Lesson Activities) Description: A game perfect for the classroom. Your students become members of an elite medical investigation team, called into action because of a high number of mysterious infant deaths in a remote community in New Mexico. It is unclear whether the deaths are a result of an infectious disease or an inherited gene. As part of the investigation, your students must determine the cause of the deaths and what can be done to save the lives of other children in this community. Source: National Academy of Sciences | URL: https://koshland-science-museum.org/explore/genetic-disease-webquest-student

Genetic Testing - Protecting Health or Denying Rights? (Lesson Plans/Lesson Activities) Description: Case scenario and discussion questions on genetic testing Source: National Human Genome Research Institute | URL: http://www.genome.gov/25019907

Genetic Testing: Road Map or Crystal Ball? (Lesson Plans/Lesson Activities) Description: Students are exposed to the pros and cons of genetic testing and must take a stand by writing a position paper, after viewing the "Who Gets to Know?" video and/or reading case studies from the Our Genes/Our Choices series. Source: PBS & WGBH Educational Foundation | URL: http://www.pbs.org/inthebalance/archives/ourgenes/lesson_genetictesting.html

Genetic Timeline (Lesson Plans/Lesson Activities) Description: A lesson plan highlighting key discoveries that have led to our present understanding of the human genome Source: National Human Genome Research Institute | URL: http://www.genome.gov/10506099

Genetic Variation within the One Human Race (Lesson Plans/Lesson Activities) Description: Through this lesson, students will understand the pattern of genetic variation among humans. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/genetic-variation-within-one-human-race/

Genetics and Reproduction (Lesson Plans/Lesson Activities) Description: This lesson addresses the genetic reproductive technologies that are being used by individuals who, for a variety of reasons, wish to know and/or have some choice about the genetic makeup of their children. It begins with a discussion of the technologies that can reveal the genetic makeup of fetuses and then moves on to a technology called preimplantation genetic diagnosis (PGD). The goal of this lesson is to give students an opportunity to discuss many aspects of PGD such that they become aware of the diversity of opinions surrounding PGD. Source: Personal Genetics Education Project | URL: http://www.pged.org/lesson-plans/#reproduction

Genetics, Jobs and Your Rights (Lesson Plans/Lesson Activities) Description: The lesson explores the Genetic Information Nondiscrimination Act (GINA), called the first civil rights legislation of the 21st century by former Massachusetts Senator Ted Kennedy. Learning about the history of genetic discrimination in the workplace, along with the progress being made to ensure workers do not have information about their DNA used inappropriately, is key to seeing the potential of personal genetics come to fruition. Source: Personal Genetics Education Project | URL: http://www.pged.org/lesson-plans/#GINA

Genome Editing and CRISPR Lesson Plan (Lesson Plans/Lesson Activities) Description: Through this lesson plan you will explore with your students how advances in our ability to change genomes may impact individuals and society. Source: Personal Genetics Education Project | URL: http://pged.org/lesson-plans/#CRISPR

Genomic Resource Center - Gender and Genetics Description: A seven part module with case studies to help your student explore the relationship between gender and genetics. Through the module they will learn more about how biological and sociocultural factors interact to influence behavior and gender identity. Source: World Health Organization | URL: http://www.who.int/genomics/gender/en/

Genomics and Human Identity (Lesson Plans/Lesson Activities) Description: Bring genomics to life for your high school students with this lesson plan. The lessons encourage hands-on, inquirybased learning and include genomic concepts and research projects. Source: National Human Genome Research Institute and the Smithsonian National Museum of Natural History | URL: https://unlockinglifescode.org/connections/newsletter/genomics-and-human-identity

Genomics and Inheritance (Lesson Plans/Lesson Activities) Description: This University of North Carolina teaching module teaches students about the human genome and what makes us each unique, how traits are inherited, and how Genome Wide Association Studies (GWAS) are helping to identify genes responsible for complex human diseases. Hands on activities include the Genetic Wheel (which shows how inherited traits make each of us incredibly unique) and a GWAS activity where students get to identify a genetic marker contributing to a human disease. Source: UNC School of Medicine | URL: http://ncdnaday.org/learn-more/resources-2/

History, Eugenics and Genetics (Lesson Plans/Lesson Activities) Description: This lesson provides students with a historical overview of the American eugenics movement and highlights some of the advances and breakthroughs that have been achieved through genetic and genomic research. Many people fear that new advances in genetics, particularly embryo screening and analysis of fetal DNA, could lead to a new era of eugenics. The goal of this lesson is for students to start discussing these topics so that they can understand the complexity of the issues and engage in conversations that contrast the dangers of eugenics with the benefits that can come from genetic information. Source: Personal Genetics Education Project | URL: http://www.pged.org/lesson-plans/#eugenics

HIV Vaccines (Lesson Plans/Lesson Activities) Description: A curriculum unit exploring the scientific and ethical issues involved in clinical HIV vaccine trials using human research participants. Source: The Northwest Association for Biomedical Research | URL: https://www.nwabr.org/teacher-center/hiv-vaccines#overview

How does genotyping work? (Lesson Plans/Lesson Activities) Description: Students learn about DNA extraction, PCR, restriction digest, and gel electrophoresis through a combination of virtual labs and class discussion. Students learn about the TAS2R38 gene which is involved in the ability to taste bitter foods. Students perform simple bioinformatics using primer sequences and allele sequences of TAS2R38. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=4&l=2&c=0

Human Genetic Variation: A Flipped Classroom Exercise in Cultural Competency (Lesson Plans/Lesson Activities) Description: An expert authored advanced in-class case discussion teaching concepts of population genetics and genetic variation. Source: Genetics Society of America | URL: http://www.genetics-gsa.org/education/GSAPREP.2013.003.shtml

Humans in Research (Lesson Plans/Lesson Activities) Description: A curriculum supplement introducing how research with humans is conducted, the rules and regulations involved, and the bioethical principles that guide scientists when involving humans in research. Source: The Northwest Association for Biomedical Research | URL: https://www.nwabr.org/teacher-center/humans-research#overview

Immunology (Lesson Plans/Lesson Activities) Description: This teaching module will give students an understanding of the two major arms of our immune system: innate immunity and adaptive immunity. Students will participate in two interactive games that demonstrate how antibiotic resistant bacteria come into existence and how vaccines work. This model will explore the importance of vaccines for public health. Source: UNC School of Medicine | URL: http://ncdnaday.org/learn-more/resources-2/

Inside/Outside the Human Genome Project (Lesson Plans/Lesson Activities) Description: In this cooperative learning activity for grades 6-8, students combine a jigsaw learning technique with an inside/outside review game to learn about DNA, genes, chromosomes and the Human Genome Project. Source: PBS & WGBH Educational Foundation | URL: http://www.pbs.org/inthebalance/archives/ourgenes/lesson_insideoutside.html

Introduction to Personal Genetics (Lesson Plans/Lesson Activities) Description: This lesson introduces students to the recent advances in genetics, genetic testing and personal genome sequencing, and presents some of the decisions and ethical challenges an individual may face regarding the use of this technology. It also highlights some of the likely benefits of personal genetics, such as gaining the motivation to take action to reduce health risks, tailoring medicines and interventions, and becoming more active and engaged healthcare consumers. Source: Personal Genetics Education Project | URL: http://www.pged.org/lesson-plans/#intro

Introductory Bioinformatics: Genetic Testing (Lesson Plans/Lesson Activities) Description: A curriculum unit exploring how bioinformatics is applied to genetic testing. Specifically, the bioinformatics tools of BLAST and Cn3D are used to investigate the genetic and molecular consequences of a mutation to the Breast Cancer Susceptibility 1 (BRCA1) gene. Source: The Northwest Association for Biomedical Research | URL: https://www.nwabr.org/teacher-center/introductory-bioinformatics-genetic-testing#overview

It is Genetic--Or Is It? (Lesson Plans/Lesson Activities) Description: This lesson for grades 9-12 explores the age-old discussion of nature vs. nurture: how much of our individuality is based on inheritance, and how much is shaped by our environment? Students explore different traits as genetic or environmental and then discuss issues of accountability for genetically-influenced personality traits. Source: PBS & WGBH Educational Foundation | URL: http://www.pbs.org/inthebalance/archives/ourgenes/lesson_genetic.html

Microbes: Too Smart for Antibiotics? (PDF 13.91 KB, Lesson Plans/Lesson Activities) Description: This lesson focuses on examining why microbes become resistant to antibiotics, as well as their roles in human health and the environment. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/evolution/lessons/meade_callahanlessons.pdf

Molecular Genetics (Lesson Plans/Lesson Activities) Description: Lesson guides and video slide show presentation on HIV viral replication and other molecular genetic topics Source: Baylor College of Medicine Center for Educational Outreach | URL: http://www.bioedonline.org/lessons-and-more/lessons-by-topic/molecular-genetics/

MRSA Gene Hunt (Lesson Plans/Lesson Activities) Description: Explore antibiotic resistannce by taking a closer look at the genomes of two strains of the bacterium, staphylococcus aureus. Source: Genome Research Limited and Wellcome Trust Sanger Institute | URL: http://www.yourgenome.org/activities/mrsa-gene-hunt

mtDNA: So What Did You Inherit from Your Mom? (PDF 26.75 KB, Lesson Plans/Lesson Activities) Description: This lesson examines the structure and function of mitochondria and its role in evolution Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/evolution/lessons/ingmanlessons.pdf

Nature and Nurture Description: In this lesson, students develop an understanding of the role both nature and nurture play in determining human traits. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/nature-and-nurture/

Origami DNA (Lesson Plans/Lesson Activities) Description: This activity brings to life the double helix structure of DNA by enabling your students to make their own paper model. Instructions and model templates are available for download. Source: Wellcome Trust Sanger Institute | URL: http://www.yourgenome.org/activities/origami-dna

Personalized Medicine (Lesson Plans/Lesson Activities) Description: Personalized medicine, also referred to as precision medicine, holds great promise to improve healthcare. As the cost of genetic analysis decreases and research advances, it is becoming increasingly possible to include the genetic make-up of a person in the repertoire of tools that inform his or her healthcare. This lesson asks students to delve into the hopes and challenges of personalized medicine and to consider the practical applications of genetic analysis in medicine. Source: Personal Genetics Education Project | URL: http://www.pged.org/lesson-plans/#PM

Personalized Medicine (aka Pharmacogenomics) (Lesson Plans/Lesson Activities) Description: In this teaching module students will learn about the concept of personalized medicine; how differences in our genes affect whether a drug treatment will be successful or have serious side effects, and how we can use this information to customize treatments for individual patients. Students will participate in a hands-on activity to further demonstrate how subtle genetic differences affect a patients response to medication. Source: UNC School of Medicine | URL: http://ncdnaday.org/learn-more/resources-2/

Protecting Athletes with Genetic Conditions: Sickle Cell Trait (Lesson Plans/Lesson Activities) Description: As the genetic basis for many health conditions is revealed, some doctors, coaches, and academic and athletic organizations are wondering whether genetic analysis can provide health and safety benefits for athletes. As of 2013, the National Collegiate Athletic Association (NCAA), the governing body of college sports in the United States, began screening all of its athletes for the genetic condition sickle cell trait (SCT). This lesson explores the discussion surrounding this policy and asks students to examine how genetics might impact their own athletic choices and options. Source: Personal Genetics Education Project | URL: http://www.pged.org/lesson-plans/#SCT

Race and Genes (Lesson Plans/Lesson Activities) Description: Visible traits of the human phenotype associated with specific races are influenced by a common set of genes all humans share, the genome, and environmental interactions. Culture determines how they are perceived. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/race-and-genes/

Risks and Benefits (Lesson Plans/Lesson Activities) Description: This lesson provides students with an opportunity to further their understanding of the risks and benefits associated with innovations in science and technology. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/risks-and-benefits/

Roots: The Ancestry of Modern People (PDF 13.91 KB, Lesson Plans/Lesson Activities) Description: This lesson examines the two main models of the origin of modern humans. Students can map the movements of early humans, consider what it takes to be a paleoanthropologist, write a news flash about Lucy’s discovery, chart a book plot about the adventures of an early hominid, and create a sketchbook of hominid fossils. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/evolution/lessons/johansonlessons.pdf

Scientific Themes in Personal Genetics (Lesson Plans/Lesson Activities) Description: This lesson introduces students to scientific concepts in genetics that have broad implications for individuals and for society. Students will be asked to consider the role of DNA in our personal and cultural identities as well as our understanding of diversity. They will come away with a perspective that the benefits of personal genetics can only come to light when we understand the potential and the concerns. Source: Personal Genetics Education Project | URL: http://www.pged.org/lesson-plans/#primer

Sequence Bracelets Description: In this activity you can make a bracelet of DNA sequence from organisms including a human, chimpanzee, butterfly, carnivorous plant or flesh-eating bacteria. Source: Genome Research Limited and Wellcome Trust Sanger Institute | URL: http://www.yourgenome.org/activities/sequence-bracelets

Sex Determination (Lesson Plans/Lesson Activities) Description: This lesson explores sex determination in mammals. Students first share their conceptions about the genetics of sex determination, then using normal and abnormal human karyotypes, students hone in on their hypothesis. The case of XY females is used to explain the presence of the SRY gene on the Y chromosome, which must produce active protein in order for a male to develop. The lesson ends by exploring other sex-determination systems in animals and their similarities and differences. Source: The American Society of Human Genetics | URL: http://www.ashg.org/cgi-bin/gena/glesson.pl?s=LSN&t=1&l=1&c=0

Stem Cell Research (Lesson Plans/Lesson Activities) Description: Lesson plans exploring the scientific and ethical issues involved in stem cell research. Source: The Northwest Association for Biomedical Research | URL: https://www.nwabr.org/teacher-center/stem-cell-research#overview

Stem Cells (Lesson Plans/Lesson Activities) Description: A collection of activities to help students learn about stem cells and consider their potential in research and health. Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/stemcells/

Teacher Guide - Have Your DNA and Eat It Too (PDF 266.17 KB, Lesson Plans/Lesson Activities) Description: Lesson plan on the structure of DNA and a class activity building an edible double helix Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/dna/HaveYourDNAandEatItToo.pdf

Technological Advances in Health (Lesson Plans/Lesson Activities) Description: Students will learn how technology influences human existence by examining the benefits and risks of different biotechnological advances. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/technological-advances-in-health/

Technology and Inequality (Lesson Plans/Lesson Activities) Description: In this lesson, students become more familiar with different types of technology, and to understand that not all people have the same access to technology. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/technology-and-inequality/

The Human Genome Project Description: Download component parts of the educational CD, The Human Genome Project Source: National Human Genome Research Institute | URL: http://www.genome.gov/Pages/EducationKit/download.html

The Illusion of Race (Lesson Plans/Lesson Activities) Description: The goal of this lesson is to have students investigate both genetic and societal consequences of these often artificial and evolving classifications. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/the-illusion-of-race/

The New Science of Addiction - Genetics and the Brain (Lesson Plans/Lesson Activities) Description: Nine high quality lesson plans teaching a variety of topics, including the genetics of drug addiction and the origin, effect, and medical consequence of drug abuse Source: Genetics Science Learning Center at the University of Utah | URL: http://teach.genetics.utah.edu/content/addiction/

The Probabilities of Problems: A Look at Inheritance (Lesson Plans/Lesson Activities) Description: Students learn how to calculate the the probabilities of passing on certain genetic disorders and then evaluate case studies involving genetic testing. Source: PBS & WGBH Educational Foundation | URL: http://www.pbs.org/inthebalance/archives/ourgenes/lesson_probabilities.html

The Social Nature of Scientific Research (Lesson Plans/Lesson Activities) Description: A curriculum supplement introducing students to ways in which scientific research is conducted, how social forces influence scientific priorities, and how basic scientific research may, or may not, support medical applications for human health Source: The Northwest Association for Biomedical Research | URL: https://www.nwabr.org/teacher-center/nature-scientific-research-0#overview

Thinnest Material Description: Learn about the thinnest material in the world that was created using nanotechnology. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/science-news/science-updates/thinnest-material/

Variation in Human Skin Color (Lesson Plans/Lesson Activities) Description: In this lesson, students explore the factors that control variation in human skin color and the implications of this information for human society. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/variation-in-human-skin-color/

What Can I Learn From Worms? Regeneration, Stem Cells, and Models (Lesson Plans/Lesson Activities) Description: A series of high quality lesson plans exploring a variety of topics including the cell cycle and the use of model species in biomedical research. You may need to register to view the lesson plans, but the plans and registration is free. Source: Project NEURON, University of Illinois | URL: https://neuron.illinois.edu/units/what-can-i-learn-from-worms

Who Owns Rights To Pharmacogenetic Information? (PDF 28.17 KB, Lesson Plans/Lesson Activities) Description: This lesson examines potential benefits, risks, and ethical concerns of designer drugs. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/genomics/lessons/barashlessons.pdf

Why Teach Bioethics? Description: An article exploring why it is important for teachers to incorporate bioethics in their classrooms and links to additional resources. Source: American Institute of Biological Sciences | URL: http://www.actionbioscience.org/education/csongradi.html

Women in Medicine - Past and Future (Lesson Plans/Lesson Activities) Description: In this investigation, students will compare the careers of two women, a century apart, involved in medical research. Source: American Association for the Advancement of Science | URL: http://sciencenetlinks.com/lessons/women-in-medicine-past-and-future/

Yummy Gummy DNA Description: Make your own edible DNA double helix out of sweets. Source: Genome Research Limited and Wellcome Trust Sanger Institute | URL: http://www.yourgenome.org/activities/yummy-gummy-dna

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