Front Cell Infect Microbiol. 2013; 3: 106. Published online 2013 Dec 24. Prepublished online 2013 Oct 31. doi: 10.3389/fcimb.2013.00106
PMCID: PMC3871965 PMID: 24400226
Yersinia pestis: mechanisms of entry into and resistance to the host cell Yuehua Ke, 1,2 Zeliang Chen, 1,* and Ruifu Yang2,* 1 Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China 2 Laboratory of Analytical Microbiology, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, China Edited by: Thomas Dandekar, University of Würzburg, Germany Reviewed by: William Picking, Oklahoma State University, USA; Stacey Gilk, Indiana University School of Medicine, USA *Correspondence: Zeliang Chen, Department of Infectious Disease Control, Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing 100071, China e-mail:
[email protected]; Ruifu Yang, Laboratory of Analytical Microbiology, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing 100071, China e-mail:
[email protected] This article was submitted to the journal Frontiers in Cellular and Infection Microbiology. Received 2013 Oct 8; Accepted 2013 Dec 10. Copyright © 2013 Ke, Chen and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. This article has been cited by other articles in PMC.
Abstract
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Introduction
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Life cycle of Y. pestis during infection
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Phagocytic receptors of host cells and invasive ligands of bacteria
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Invasion factors
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Ail
Plasminogen activator
Other
Antiphagocytic factor
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Psa
F1
YopH
YopE
YopT
YpkA/YopO
Switch from invasive to antiphagocytic status
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Conclusions
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Conflict of interest statement
Acknowledgments
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References
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